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Brenda J. Weigel
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Journal Articles

Efficacy of the Allosteric MEK Inhibitor Trametinib in Relapsed and Refractory Juvenile Myelomonocytic Leukemia: A Report from the Children's Oncology Group

Elliot Stieglitz, Alex Lee, Steven P. Angus, Christopher Davis, Donald Barkauskas, David Hall, Scott C. Kogan, Julia Meyer, Steven D. Rhodes, Xiaoling Xuei, Kevin Shannon, Mignon L. Loh, Elizabeth Fox, Brenda J. Weigel
Journal: Blood
Blood (2023) 142 (Supplement 1): 74.
https://doi.org/10.1182/blood-2023-173153
Published: 2023
Journal Articles

Safety and Activity of Flotetuzumab in Pediatric and Young Adult Patients with Relapsed/Refractory Acute Myeloid Leukemia: Results from the COG PEPN1812 Phase 1 Trial

Adam J. Lamble, Xiaowei Liu, Charles Minard, Olga Militano, Melanie Brooke Bernhardt, Todd M. Cooper, Edward A. Kolb, Erin H. Breese, Elizabeth Fox, Sarah K Tasian, Brenda J. Weigel
Journal: Blood
Blood (2022) 140 (Supplement 1): 6209–6210.
https://doi.org/10.1182/blood-2022-158029
Published: 2022
Journal Articles

MEK Inhibition Demonstrates Activity in Relapsed, Refractory Patients with Juvenile Myelomonocytic Leukemia: Results from COG Study ADVL1521

Elliot Stieglitz, Mignon L. Loh, Julia Meyer, Chujing Zhang, Donald A Barkauskas, David Hall, Elizabeth Fox, Brenda J. Weigel
Journal: Blood
Blood (2021) 138 (Supplement 1): 3679.
https://doi.org/10.1182/blood-2021-144850
Published: 2021
Journal Articles

Safety of Palbociclib in Combination with Chemotherapy in Pediatric and Young Adult Patients with Relapsed/Refractory Acute Lymphoblastic Leukemia and Lymphoma: A Children's Oncology Group Pilot Study

Elizabeth A. Raetz, MD, David T. Teachey, MD, Charles Minard, PhD, Xiaowei Liu, MS, Robin Norris, MD MS, MPH, Joel Reid, PhD, Thalia Beeles, MPh, Lia Gore, MD, Elizabeth Fox, MD, Mignon L. Loh, MD, Brenda J. Weigel, MDMSc, William L. Carroll, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 20–21.
https://doi.org/10.1182/blood-2020-141572
Published: 2020
Journal Articles

Coexpression of Tim-3 and PD-1 identifies a CD8 + T-cell exhaustion phenotype in mice with disseminated acute myelogenous leukemia

Qing Zhou, Meghan E. Munger, Rachelle G. Veenstra, Brenda J. Weigel, Mitsuomi Hirashima, David H. Munn, William J. Murphy, Miyuki Azuma, Ana C. Anderson, Vijay K. Kuchroo, Bruce R. Blazar
Journal: Blood
Blood (2011) 117 (17): 4501–4510.
https://doi.org/10.1182/blood-2010-10-310425
Published: 2011
Includes: Supplemental data
Journal Articles

Program death-1 signaling and regulatory T cells collaborate to resist the function of adoptively transferred cytotoxic T lymphocytes in advanced acute myeloid leukemia

Qing Zhou, Meghan E. Munger, Steven L. Highfill, Jakub Tolar, Brenda J. Weigel, Megan Riddle, Arlene H. Sharpe, Daniel A. Vallera, Miyuki Azuma, Bruce L. Levine, Carl H. June, William J. Murphy, David H. Munn, Bruce R. Blazar
Journal: Blood
Blood (2010) 116 (14): 2484–2493.
https://doi.org/10.1182/blood-2010-03-275446
Published: 2010
Includes: Supplemental data
Journal Articles

Depletion of endogenous tumor-associated regulatory T cells improves the efficacy of adoptive cytotoxic T-cell immunotherapy in murine acute myeloid leukemia

Qing Zhou, Christoph Bucher, Meghan E. Munger, Steven L. Highfill, Jakub Tolar, David H. Munn, Bruce L. Levine, Megan Riddle, Carl H. June, Daniel A. Vallera, Brenda J. Weigel, Bruce R. Blazar
Journal: Blood
Blood (2009) 114 (18): 3793–3802.
https://doi.org/10.1182/blood-2009-03-208181
Published: 2009
Includes: Supplemental data
Journal Articles

Insights into the mechanism of FTY720 and compatibility with regulatory T cells for the inhibition of graft-versus-host disease (GVHD)

Patricia A. Taylor, Michael J. Ehrhardt, Christopher J. Lees, Jakub Tolar, Brenda J. Weigel, Angela Panoskaltsis-Mortari, Jonathan S. Serody, Volker Brinkmann, Bruce R. Blazar
Journal: Blood
Blood (2007) 110 (9): 3480–3488.
https://doi.org/10.1182/blood-2007-05-087940
Published: 2007
Journal Articles

Comparative analysis of murine marrow–derived dendritic cells generated by Flt3L or GM-CSF/IL-4 and matured with immune stimulatory agents on the in vivo induction of antileukemia responses

Brenda J. Weigel, Narender Nath, Patricia A. Taylor, Angela Panoskaltsis-Mortari, Wei Chen, Arthur M. Krieg, Kenneth Brasel, Bruce R. Blazar
Journal: Blood
Blood (2002) 100 (12): 4169–4176.
https://doi.org/10.1182/blood-2002-04-1063
Published: 2002
Journal Articles

In vitro tumor-pulsed or in vivo Flt3 ligand–generated dendritic cells provide protection against acute myelogenous leukemia in nontransplanted or syngeneic bone marrow–transplanted mice

Anna B. Pawlowska, Satoshi Hashino, Hilary McKenna, Brenda J. Weigel, Patricia A. Taylor, Bruce R. Blazar
Journal: Blood
Blood (2001) 97 (5): 1474–1482.
https://doi.org/10.1182/blood.V97.5.1474
Published: 2001