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Journal Articles

Drilling down interferon in GVHD/GVL

William J. Murphy

Blood (2023) 141 (8): 821–823.

https://doi.org/10.1182/blood.2022019232

Published: 2023

Journal Articles

Giving alloHSCT a needed LIF(t)

William J. Murphy

Blood (2022) 140 (19): 2008–2009.

https://doi.org/10.1182/blood.2022018006

Published: 2022

Journal Articles

BET-bromodomain and EZH2 inhibitor–treated chronic GVHD mice have blunted germinal centers with distinct transcriptomes

Blood (2022) 139 (19): 2983–2997.

https://doi.org/10.1182/blood.2021014557

Published: 2022

Includes: Supplemental data

Journal Articles

Increased efficacy of dual proinflammatory cytokine blockade on acute GVHD while maintaining GVT effects

Lam T. Khuat, Logan V. Vick, Cordelia Dunai, Craig P. Collins, Shyam K. More, Catherine T. Le, Chien-Chun Steven Pai, Kevin M. Stoffel, Emanual Maverakis, Robert J. Canter, Arta M. Monjazeb, Dan L. Longo, Mehrdad Abedi, Eunju Choi, Bruce R. Blazar, Maneesh Dave, William J. Murphy

Blood (2021) 138 (24): 2583–2588.

https://doi.org/10.1182/blood.2021011216

Published: 2021

Includes: Supplemental data

Journal Articles

AML Cell Vaccines Co-Expressing CD80 and IL-15/IL-15 Receptor Alpha Induce Activation and Cytolytic Activity in Post Remission Autologous Patient PBMC Ex Vivo

Xinyue Wang, Jeffrey P. Fung, Giulia Parisi, Francesca M. Olguin, Nathaniel Z. Rothschild, Kenneth I. Weinberg, William J. Murphy, Donald B. Kohn, Karin L. Gaensler

Blood (2021) 138 (Supplement 1): 1706.

https://doi.org/10.1182/blood-2021-151614

Published: 2021

Journal Articles

Repurposing a novel anti-cancer RXR agonist to attenuate murine acute GVHD and maintain graft-versus-leukemia responses

Blood (2021) 137 (8): 1090–1103.

https://doi.org/10.1182/blood.2020005628

Published: 2021

Includes: Supplemental data

Journal Articles

Inhibition of inositol kinase B controls acute and chronic graft-versus-host disease

Blood (2020) 135 (1): 28–40.

https://doi.org/10.1182/blood.2019000032

Published: 2020

Includes: Supplemental data

Journal Articles

Obesity-Induced Microbiome Alterations Result in Severe Gastrointestinal Graft-Versus-Host Disease Following Allogeneic Hematopoietic Stem Cell Transplantation

Blood (2019) 134 (Supplement_1): 1922.

https://doi.org/10.1182/blood-2019-127743

Published: 2019

Journal Articles

Danger-associated extracellular ATP counters MDSC therapeutic efficacy in acute GVHD

Blood (2019) 134 (19): 1670–1682.

https://doi.org/10.1182/blood.2019001950

Published: 2019

Journal Articles

Small-molecule BCL6 inhibitor effectively treats mice with nonsclerodermatous chronic graft-versus-host disease

Blood (2019) 133 (1): 94–99.

https://doi.org/10.1182/blood-2018-03-839993

Published: 2019

Journal Articles

Therapeutic regulatory T-cell adoptive transfer ameliorates established murine chronic GVHD in a CXCR5-dependent manner

Cameron McDonald-Hyman, Ryan Flynn, Angela Panoskaltsis-Mortari, Nicholas Peterson, Kelli P. A. MacDonald, Geoffrey R. Hill, Leo Luznik, Jonathan S. Serody, William J. Murphy, Ivan Maillard, David H. Munn, Laurence A. Turka, John Koreth, Corey S. Cutler, Robert J. Soiffer, Joseph H. Antin, Jerome Ritz, Bruce R. Blazar

Blood (2016) 128 (7): 1013–1017.

https://doi.org/10.1182/blood-2016-05-715896

Published: 2016

Journal Articles

Targeted Rho-associated kinase 2 inhibition suppresses murine and human chronic GVHD through a Stat3-dependent mechanism

Blood (2016) 127 (17): 2144–2154.

https://doi.org/10.1182/blood-2015-10-678706

Published: 2016

Includes: Supplemental data

Journal Articles

Mouse host unlicensed NK cells promote donor allogeneic bone marrow engraftment

Maite Alvarez, Kai Sun, William J. Murphy

Blood (2016) 127 (9): 1202–1205.

https://doi.org/10.1182/blood-2015-08-665570

Published: 2016

Includes: Supplemental data

Journal Articles

ASXL1-Mutated Donor HSCs Evolved into FLT3-ITD Positive AML in the Unrelated Donor and FLT3-ITD Negative AML in the Recipient after Transplant

Zhongwen Liu, MD, Hongxing Liu, MD, Yanli Zhang, MD, Dai Kong, MD, Jie Shi, MD, Yin Zhang, MD, Meiying Wen, Yongping Song, MD PhD, Chunrong Tong, MD, Mingyi Chen, MD PhD, William J. Murphy, PhD, Kai Sun, MD PhD

Blood (2015) 126 (23): 5403.

https://doi.org/10.1182/blood.V126.23.5403.5403

Published: 2015

Journal Articles

Loss of Programmed Death Ligand-1 Expression on Donor T Cells Lessens Acute Graft-Versus-Host Disease Lethality

Blood (2015) 126 (23): 147.

https://doi.org/10.1182/blood.V126.23.147.147

Published: 2015

Journal Articles

GVHD-associated, inflammasome-mediated loss of function in adoptively transferred myeloid-derived suppressor cells

Brent H. Koehn, Petya Apostolova, Jessica M. Haverkamp, Jeffrey S. Miller, Valarie McCullar, Jakub Tolar, David H. Munn, William J. Murphy, Willie June Brickey, Jonathan S. Serody, Dmitry I. Gabrilovich, Vincenzo Bronte, Peter J. Murray, Jenny P.-Y. Ting, Robert Zeiser, Bruce R. Blazar

Blood (2015) 126 (13): 1621–1628.

https://doi.org/10.1182/blood-2015-03-634691

Published: 2015

Includes: Supplemental data

Journal Articles

Targeting Syk-activated B cells in murine and human chronic graft-versus-host disease

Blood (2015) 125 (26): 4085–4094.

https://doi.org/10.1182/blood-2014-08-595470

Published: 2015

Includes: Supplemental data

Journal Articles

B7-H3 expression in donor T cells and host cells negatively regulates acute graft-versus-host disease lethality

Rachelle G. Veenstra, Ryan Flynn, Katharina Kreymborg, Cameron McDonald-Hyman, Asim Saha, Patricia A. Taylor, Mark J. Osborn, Angela Panoskaltsis-Mortari, Annette Schmitt-Graeff, Elisabeth Lieberknecht, William J. Murphy, Jonathan S. Serody, David H. Munn, Gordon J. Freeman, James P. Allison, Tak W. Mak, Marcel van den Brink, Robert Zeiser, Bruce R. Blazar

Blood (2015) 125 (21): 3335–3346.

https://doi.org/10.1182/blood-2014-09-603357

Published: 2015

Includes: Supplemental data

Journal Articles

Adiposity As a Principal Component of Lethal Cytokine Storm Following Cancer Immunotherapy in Aged Mice

Annie Mirsoian, Myriam N. Bouchlaka, BS, PhD, Gail Sckisel, PhD, Mingyi Chen, MD PhD, Chien-Chun Steven Pai, Emanuel Maverakis, MD, Richard Spencer, MD PhD FACP, Kenneth Fishbein, PhD, Sana Siddiqui, PhD, Arta Monjazeb, MDPhD, Bronwen Martin, PhD, Stuart Maudsley, PhD, Charles Hesdorffer, Luigi Ferrucci, MD PhD, Dan L. Longo, MD, Bruce R. Blazar, MD, Robert Wiltrout, PhD, Dennis D Taub, PhD, William J Murphy, PhD

Blood (2014) 124 (21): 460.

https://doi.org/10.1182/blood.V124.21.460.460

Published: 2014

Journal Articles

Targeting BCL6 and Germinal Centers (GCs) in Chronic Graft-Versus-Host Disease (cGVHD) Using Direct and Epigenomic Therapies

Blood (2014) 124 (21): 535.

https://doi.org/10.1182/blood.V124.21.535.535

Published: 2014

NARROW

Drilling down interferon in GVHD/GVL

Giving alloHSCT a needed LIF(t)

BET-bromodomain and EZH2 inhibitor–treated chronic GVHD mice have blunted germinal centers with distinct transcriptomes

Increased efficacy of dual proinflammatory cytokine blockade on acute GVHD while maintaining GVT effects

AML Cell Vaccines Co-Expressing CD80 and IL-15/IL-15 Receptor Alpha Induce Activation and Cytolytic Activity in Post Remission Autologous Patient PBMC Ex Vivo

Repurposing a novel anti-cancer RXR agonist to attenuate murine acute GVHD and maintain graft-versus-leukemia responses

Inhibition of inositol kinase B controls acute and chronic graft-versus-host disease

Obesity-Induced Microbiome Alterations Result in Severe Gastrointestinal Graft-Versus-Host Disease Following Allogeneic Hematopoietic Stem Cell Transplantation

Danger-associated extracellular ATP counters MDSC therapeutic efficacy in acute GVHD

Small-molecule BCL6 inhibitor effectively treats mice with nonsclerodermatous chronic graft-versus-host disease

Therapeutic regulatory T-cell adoptive transfer ameliorates established murine chronic GVHD in a CXCR5-dependent manner

Targeted Rho-associated kinase 2 inhibition suppresses murine and human chronic GVHD through a Stat3-dependent mechanism

Mouse host unlicensed NK cells promote donor allogeneic bone marrow engraftment

ASXL1-Mutated Donor HSCs Evolved into FLT3-ITD Positive AML in the Unrelated Donor and FLT3-ITD Negative AML in the Recipient after Transplant

Loss of Programmed Death Ligand-1 Expression on Donor T Cells Lessens Acute Graft-Versus-Host Disease Lethality

GVHD-associated, inflammasome-mediated loss of function in adoptively transferred myeloid-derived suppressor cells

Targeting Syk-activated B cells in murine and human chronic graft-versus-host disease

B7-H3 expression in donor T cells and host cells negatively regulates acute graft-versus-host disease lethality

Adiposity As a Principal Component of Lethal Cytokine Storm Following Cancer Immunotherapy in Aged Mice

Targeting BCL6 and Germinal Centers (GCs) in Chronic Graft-Versus-Host Disease (cGVHD) Using Direct and Epigenomic Therapies

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American Society of Hematology

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American Society of Hematology

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