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Alexandra Zanin-Zhorov
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Journal Articles

KD025-208: A Phase 2a Study of KD025 for Patients with Chronic Graft Versus Host Disease (cGVHD) — Pharmacodynamics and Updated Results

Madan Jagasia, MD MS, Amandeep Salhotra, MD, Carlos R. Bachier, MD, James Essell, MD, Daniel J. Weisdorf, MD, Behyar Zoghi, MD PhD, Laurie S. Green, MD, Olivier Schueller, PhD, Alexandra Zanin-Zhorov, PhD, Jonathan M. Weiss, PhD, David Eiznhamer, PhD, Sanjay K. Aggarwal, Bruce R. Blazar, MD, Stephanie J. Lee, MD MPH
Journal: Blood
Blood (2018) 132 (Supplement 1): 602.
https://doi.org/10.1182/blood-2018-99-111896
Published: 2018
Journal Articles

Initial Results of KD025-208: A Phase 2a Open Label Trial of KD025 for Steroid-Dependent Chronic Graft Versus Host Disease

Aleksandr Lazaryan, MD PhD MPH, Stephanie J Lee, MD MPH, Amandeep Salhotra, MD, Madan Jagasia, MD MBBS, MS, James Essell, MD, Alexandra Zanin-Zhorov, PhD, Beth Mac Gillivray, MSc, Olivier Schueller, PhD, David Eiznhamer, PhD, Bruce Blazar, MD, John L. Ryan, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3256.
https://doi.org/10.1182/blood.V130.Suppl_1.3256.3256
Published: 2017
Journal Articles

Targeted Rho-associated kinase 2 inhibition suppresses murine and human chronic GVHD through a Stat3-dependent mechanism

Ryan Flynn, Katelyn Paz, Jing Du, Dawn K. Reichenbach, Patricia A. Taylor, Angela Panoskaltsis-Mortari, Ante Vulic, Leo Luznik, Kelli K. P. MacDonald, Geoffrey R. Hill, Melanie S. Nyuydzefe, Jonathan M. Weiss, Wei Chen, Alissa Trzeciak, Jon S. Serody, Ethan G. Aguilar, William J. Murphy, Ivan Maillard, David Munn, John Koreth, Corey S. Cutler, Joseph H. Antin, Jerome Ritz, Samuel D. Waksal, Alexandra Zanin-Zhorov, Bruce R. Blazar
Journal: Blood
Blood (2016) 127 (17): 2144–2154.
https://doi.org/10.1182/blood-2015-10-678706
Published: 2016
Includes: Supplemental data
Journal Articles

A Selective and Potent Rock 2 Inhibitor (KD025) Decreases Human STAT3-Dependent IL-21 and IL-17 Production and Experimental Chronic Graft-Versus-Host Disease (cGVHD)

Alexandra Zanin-Zhorov, PhD, Ryan Flynn, Leo Luznik, MD, Angela Panoskaltsis-Mortari, PhD, Du Jing, Katelyn Goodman, Jonathan Weiss, PhD, Melanie Nyuydzefe, Wei Chen, PhD, Jonathan S Serody, MD, Kelli PA MacDonald, Geoffrey R Hill, John O'Shea, MD, Maria Roche, Sara Weiss, PhD, Samuel Waksal, PhD, Bruce R. Blazar, MD
Journal: Blood
Blood (2014) 124 (21): 540.
https://doi.org/10.1182/blood.V124.21.540.540
Published: 2014
Journal Articles

Toll-like receptors and their ligands control mesenchymal stem cell functions

Meirav Pevsner-Fischer, Vered Morad, Michal Cohen-Sfady, Liat Rousso-Noori, Alexandra Zanin-Zhorov, Shmuel Cohen, Irun R. Cohen, Dov Zipori
Journal: Blood
Blood (2006) 109 (4): 1422–1432.
https://doi.org/10.1182/blood-2006-06-028704
Published: 2006