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Jerome Ritz
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Journal Articles

Phase 1 study of CAR-37 T cells in patients with relapsed or refractory CD37 + lymphoid malignancies

Clinical Trials & Observations
Matthew J. Frigault, Charlotte E. Graham, Trisha R. Berger, Julie Ritchey, Nora K. Horick, Areej El-Jawahri, Irene Scarfò, Andrea Schmidts, Nicholas J. Haradhvala, Marc Wehrli, Won-Ho Lee, Aiyana L. Parker, Hadley R. Wiggin, Amanda Bouffard, Aonkon Dey, Mark B. Leick, Katelin Katsis, Eva L. Elder, Maria A. Dolaher, Daniella T. Cook, Alena A. Chekmasova, Lu Huang, Sarah Nikiforow, Heather Daley, Jerome Ritz, Myriam Armant, Fred Preffer, John F. DiPersio, Valentina Nardi, Yi-Bin Chen, Kathleen M. E. Gallagher, Marcela V. Maus
Journal: Blood
Blood (2024) 144 (11): 1153–1167.
https://doi.org/10.1182/blood.2024024104
Published: 2024
Includes: Supplemental data
Journal Articles

Baseline Immune State and T-cell Clonal Kinetics are Associated with Durable Response to CAR-T Therapy in Large B-cell Lymphoma

Clinical Trials & Observations
Katie Maurer, Isabella N Grabski, Roch Houot, Satyen H. Gohil, Shogo Miura, Robert A Redd, Haoxiang Lyu, Wesley Lu, Yohei Arihara, Justin Budka, Mikaela McDonough, Michela Ansuinelli, Carol G Reynolds, Heather Jacene, Shuqiang Li, Kenneth J Livak, Jerome Ritz, Brodie Miles, Mike Mattie, Donna S. Neuberg, Rafael A. Irizarry, Philippe Armand, Catherine J Wu, Caron A. Jacobson
Journal: Blood
Blood blood.2024024381.
https://doi.org/10.1182/blood.2024024381
Published: 2024
Includes: Supplemental data
Journal Articles

Differentiation of BCMA-specific induced pluripotent stem cells into rejuvenated CD8αβ + T cells targeting multiple myeloma

Jooeun Bae, Shuichi Kitayama, Zach Herbert, Laurence Daheron, Keiji Kurata, Derin B. Keskin, Kenneth Livak, Shuqiang Li, Mubin Tarannum, Rizwan Romee, Mehmet Samur, Nikhil C. Munshi, Shin Kaneko, Jerome Ritz, Kenneth C. Anderson
Journal: Blood
Blood (2024) 143 (10): 895–911.
https://doi.org/10.1182/blood.2023020528
Published: 2024
Includes: Supplemental data
Journal Articles

Expansion, Persistence, and Characteristics of Autologous, Bhv-1100 Armored Memory-like NK Cells Infused Prior to Autologous Stem Cell Transplant in MRD+ Multiple Myeloma Patients: A First-in-Human Trial

Grace Caroline Birch, Juliana Vergara-Cadavid, Mohsin Maqbool, Alba Martini, Khanlinh Dinh, Roman M. Shapiro, Michela Ansuinelli, Tuyet Nguyen, Carol Reynolds, Im Soo Y, Hope Wei, Sarah Hogan, Elizabeth Kendricken, Adam S. Sperling, Omar Nadeem, Jacob Laubach, Alissa Rybicki, Steven Schnittman, Elyse Stock, Diego Hernandez Rodriguez, Heather Daley, Sarah Nikiforow, Jerome Ritz, Robert J. Soiffer, Giada Bianchi, Rizwan Romee
Journal: Blood
Blood (2023) 142 (Supplement 1): 2105.
https://doi.org/10.1182/blood-2023-180224
Published: 2023
Journal Articles

Epitope Edited Hematopoietic Stem Cells to Enable Synergistic Immunotherapy Combinations for Acute Myeloid Leukemia

Gabriele Casirati, Andrea Cosentino, Adele Mucci, Mohammed S Mahmoud, Iratxe Ugarte Zabala, Jing Zeng, Scott Ficarro, Denise Klatt, Christian Brendel, Alessandro Rambaldi, Jerome Ritz, Jarrod Marto, Danilo Pellin, Daniel E. Bauer, Scott A Armstrong, Pietro Genovese
Journal: Blood
Blood (2023) 142 (Supplement 1): 7130.
https://doi.org/10.1182/blood-2023-189980
Published: 2023
Journal Articles

CTLA-4 Blockade Results in the Enrichment of Proliferative CD56 dim CD16 + NK Cells Following Infusion of Haploidentical Donor Memory-like Natural Killer Cells Plus IL-15 Superagonist in a Phase 1 Trial

Roman M. Shapiro, Michal Sheffer, Matthew Aaron Booker, Michael Yevgeniy Tolstorukov, Michela Ansuinelli, Moshe Sade-Feldman, Jacy Fang, Grace Caroline Birch, Juliana Vergara-Cadavid, Yasmin Z Abdulhamid, Isabel E Kaplan, Dinh Khanhlinh, Robert A. Redd, Alejandro Alonso, Denbaa Bat-Erdene, Ravindra Uppaluri, Heather Daley, Diego Hernandez Rodriguez, John Koreth, Jerome Ritz, Sarah Nikiforow, Robert J. Soiffer, Glenn J Hanna, Rizwan Romee
Journal: Blood
Blood (2023) 142 (Supplement 1): 6850.
https://doi.org/10.1182/blood-2023-178362
Published: 2023
Journal Articles

ASXL1 Truncating Mutations Drive Leukemic Resistance to T Cell Attack

Dustin McCurry, Zhongqi Ge, Jaehyun Lee, Pranaya Raparla, Thomas Koehnke, Rishi Pasumarthi, Xiaohong Leng, Oren Pasvolsky, Vinhkhang Nguyen, Katie Maurer, Shuqiang Li, Kenneth J. Livak, Elham Azizi, Robert J. Soiffer, Sachet Shukla, Ravindra Majeti, Jerome Ritz, Catherine J Wu, Jeffrey J. Molldrem, Pavan Bachireddy
Journal: Blood
Blood (2023) 142 (Supplement 1): 364.
https://doi.org/10.1182/blood-2023-189177
Published: 2023
Journal Articles

An Analytic Framework for the Prediction of Gvl Minor Histocompatibility Antigens to Prevent or Treat Post-Transplant Relapse

Nicoletta Cieri, Liang Li, Nidhi Hookeri, Kari Stromhaug, Julia Keating, Jonathan Stevens, Kameron Kooshesh, Helen Ji, Gabrielle M. Hernandez, Jennifer Abelin, Susan Klaeger, Cleo Forman, Karl Clauser, Siranush Sarkizova, Giacomo Oliveira, Livius Penter, Haesook T. Kim, William Lane, Shuqiang Li, Kenneth J. Livak, Steven A. Carr, Derin B. Keskin, Vincent T. Ho, Jerome Ritz, Robert J. Soiffer, Donna S. Neuberg, Chip Stewart, Gad Getz, Catherine J Wu
Journal: Blood
Blood (2023) 142 (Supplement 1): 361.
https://doi.org/10.1182/blood-2023-187705
Published: 2023
Journal Articles

Coordinated Immune Cell Networks in the Bone Marrow Microenvironment Define the Graft Versus Leukemia Response with Adoptive Cellular Therapy

Alexandria Maurer, Cameron Y Park, Shouvik Mani, Mehdi Borji, Crystal Shin, Livius Penter, James R Brenner, Jackson Southard, Wesley S Lu, Haoxiang Lyu, Shuqiang Li, Kenneth J. Livak, Jerome Ritz, Robert J. Soiffer, Elham Azizi, Catherine J Wu
Journal: Blood
Blood (2023) 142 (Supplement 1): 363.
https://doi.org/10.1182/blood-2023-189292
Published: 2023
Journal Articles

T-Charge™ Manufacturing of the Anti-BCMA CAR-T, Durcabtagene Autoleucel (PHE885), Promotes Expansion and Persistence of CAR-T Cells with High TCR Repertoire Diversity

Shuntaro Ikegawa, Adam S. Sperling, Michela Ansuinelli, Sarah Nikiforow, David Quinn, Dexiu Bu, Jennifer Mataraza, David Pearson, Lawrence Rispoli, Marc A Credi, Nina Orwitz, Yohei Arihara, Rao Prabhala, Lakshmi Bhavani Potluri, Carol Reynolds, Serena De Vita, Nikhil C Munshi, Jerome Ritz
Journal: Blood
Blood (2023) 142 (Supplement 1): 3469.
https://doi.org/10.1182/blood-2023-177721
Published: 2023
Journal Articles

Integrative Single-Cell Tracking of Clonal Evolution, Leukemia Phenotypes and Donor Engraftment Following Allogeneic Stem Cell Transplant Using Mitochondrial DNA Mutations

Livius Penter, Nicoletta Cieri, Katie Maurer, Haoxiang Lyu, Wesley S Lu, Giacomo Oliveira, Satyen H Gohil, Caleb Lareau, Leif S Ludwig, Shuqiang Li, Jerome Ritz, Jacqueline S. Garcia, Robert J. Soiffer, Kenneth J. Livak, Catherine J Wu
Journal: Blood
Blood (2023) 142 (Supplement 1): 3580.
https://doi.org/10.1182/blood-2023-180113
Published: 2023
Journal Articles

Effective Prevention of Steroid-Requiring Chronic Graft-Vs.-Host Disease with B Cell Depletion: A Randomized, Placebo-Controlled Trial

Corey Cutler, Haesook T. Kim, Hassan El Banna, Elizabeth Halloran, Emily Matozel, Vincent Ho, John Koreth, Mahasweta Gooptu, Roman M. Shapiro, Amar H Kelkar, Christopher James Gibson, Carol Reynolds, Michela Ansuinelli, Rayuko Tamada, Chloe Au, Zachariah Defilipp, Areej El-Jawahri, Yi-Bin Chen, Najla H El Jurdi, Daniel Weisdorf, Daniel R. Couriel, Catherine J. Lee, Bita Sahaf, Juliana Craig, Kathleen Ji, Robert J. Soiffer, David B. Miklos, Joseph Antin, Jerome Ritz
Journal: Blood
Blood (2023) 142 (Supplement 1): 649.
https://doi.org/10.1182/blood-2023-180142
Published: 2023
Journal Articles

Tracking of Leukemia and Immune Single Cell Phenotypes during Ipilimumab-Based Treatment By Long-Read Sequencing

Livius Penter, Mehdi Borji, Adi Nagler, Haoxiang Lyu, Wesley S Lu, Nicoletta Cieri, Alexandria Maurer, Giacomo Oliveira, Aziz M. Al'Khafaji, Kiran Garimella, Shuqiang Li, Donna S. Neuberg, Jerome Ritz, Robert J. Soiffer, Jacqueline S. Garcia, Kenneth J. Livak, Catherine J Wu
Journal: Blood
Blood (2023) 142 (Supplement 1): 1596.
https://doi.org/10.1182/blood-2023-180016
Published: 2023
Journal Articles

Systematic Prediction of Minor Histocompatibility Antigens to Inform GvHD Outcomes after Allogeneic Stem Cell Transplantation

Nicoletta Cieri, Nidhi Hookeri, Kari Stromhaug, Liang Li, Julia Keating, Jonathan Stevens, Kameron Kooshesh, Helen Ji, Gabrielle M. Hernandez, Jennifer Abelin, Susan Klaeger, Cleo Forman, Karl Clauser, Siranush Sarkizova, Giacomo Oliveira, Livius Penter, Haesook T. Kim, William Lane, Shuqiang Li, Kenneth J. Livak, Steven A. Carr, Derin B. Keskin, Vincent T. Ho, Jerome Ritz, Robert J. Soiffer, Donna S. Neuberg, Chip Stewart, Gad Getz, Catherine J Wu
Journal: Blood
Blood (2023) 142 (Supplement 1): 652.
https://doi.org/10.1182/blood-2023-187451
Published: 2023
Journal Articles

Post-Transplant T Cell Clonotype Diversity Is Associated with Survival in Patients with TP53-Mutated Acute Myeloid Leukemia

Nurefsan Sariipek, Kseniia R. Safina, Corey Cutler, Vincent T. Ho, John Koreth, Coleman Lindsley, Marlise R. Luskin, Jacqueline S. Garcia, Doreen Hearsey, Wesley S Lu, Shuqiang Li, Kenneth J. Livak, Gabriel K. Griffin, Robert J. Soiffer, Jerome Ritz, Catherine J Wu, Joseph H. Antin, Andrew A. Lane, Peter Van Galen, Mahasweta Gooptu
Journal: Blood
Blood (2023) 142 (Supplement 1): 2176.
https://doi.org/10.1182/blood-2023-181863
Published: 2023
Journal Articles

Baseline Immune State and T Cell Clonal Kinetics Are Associated with Response to CAR-T Therapy in Large B-Cell Lymphoma

Katie Maurer, Isabella N. Grabski, Roch Houot, Satyen H Gohil, Shogo Miura, Robert A. Redd, Haoxiang Lyu, Wesley S Lu, Brodie Miles, Mike Mattie, Yohei Arihara, Mikaela M. McDonough, Carol Reynolds, Michela Ansuinelli, Shuqiang Li, Kenneth J. Livak, Jerome Ritz, Scott Rodig, Rafael A. Irizarry, Philippe Armand, Catherine J Wu, Caron A. Jacobson
Journal: Blood
Blood (2023) 142 (Supplement 1): 223.
https://doi.org/10.1182/blood-2023-180819
Published: 2023
Journal Articles

Ipilimumab plus decitabine for patients with MDS or AML in posttransplant or transplant-naïve settings

Clinical Trials & Observations
Jacqueline S. Garcia, Yael Flamand, Livius Penter, Michael Keng, Benjamin K. Tomlinson, Lourdes M. Mendez, Paul Koller, Nicole Cullen, Yohei Arihara, Kathleen Pfaff, Jacquelyn O. Wolff, Andrew M. Brunner, Ilene Galinsky, Asad Bashey, Joseph H. Antin, Corey Cutler, Vincent Ho, Brian A. Jonas, Marlise R. Luskin, Martha Wadleigh, Eric S. Winer, Alexandra Savell, Rebecca Leonard, Taylor Robertson, Matthew S. Davids, Howard Streicher, Scott J. Rodig, Jerome Ritz, Catherine J. Wu, Daniel J. DeAngelo, Donna Neuberg, Richard M. Stone, Robert J. Soiffer
Journal: Blood
Blood (2023) 141 (15): 1884–1888.
https://doi.org/10.1182/blood.2022017686
Published: 2023
Includes: Supplemental data
Journal Articles

Mechanisms of response and resistance to combined decitabine and ipilimumab for advanced myeloid disease

Clinical Trials & Observations
Livius Penter, Yang Liu, Jacquelyn O. Wolff, Lin Yang, Len Taing, Aashna Jhaveri, Jackson Southard, Manishkumar Patel, Nicole M. Cullen, Kathleen L. Pfaff, Nicoletta Cieri, Giacomo Oliveira, Seunghee Kim-Schulze, Srinika Ranasinghe, Rebecca Leonard, Taylor Robertson, Elizabeth A. Morgan, Helen X. Chen, Minkyung H. Song, Magdalena Thurin, Shuqiang Li, Scott J. Rodig, Carrie Cibulskis, Stacey Gabriel, Pavan Bachireddy, Jerome Ritz, Howard Streicher, Donna S. Neuberg, F. Stephen Hodi, Matthew S. Davids, Sacha Gnjatic, Kenneth J. Livak, Jennifer Altreuter, Franziska Michor, Robert J. Soiffer, Jacqueline S. Garcia, Catherine J. Wu
Journal: Blood
Blood (2023) 141 (15): 1817–1830.
https://doi.org/10.1182/blood.2022018246
Published: 2023
Includes: Supplemental data
Journal Articles

Mechanisms of Response and Resistance to Combination Decitabine and Ipilimumab for Transplant Naïve and Post-Transplant AML/MDS

Livius Penter, Yang Liu, Lin Yang, Len Taing, Aashna Jhaveri, Jackson Southard, Manishkumar Patel, Jacquelyn Wolff, Nicole Cullen, Kathleen Pfaff, Nicoletta Cieri, Giacomo Oliveira, Seunghee Kim-Schulze, Srinika Ranasinghe, Rebecca Leonard, Taylor Robertson, Helen Chen, Magdalena Thurin, Shuqiang Li, Scott J. Rodig, Carrie Cibulskis, Stacey Gabriel, Jerome Ritz, Howard Streicher, Donna S. Neuberg, Stephen Hodi, Sacha Gnjatic, Kenneth J Livak, Jennifer Altreuter, Franziska Michor, Robert J Soiffer, Jacqueline S. Garcia, Catherine J. Wu
Journal: Blood
Blood (2022) 140 (Supplement 1): 10198–10199.
https://doi.org/10.1182/blood-2022-157339
Published: 2022
Journal Articles

Maintenance Therapy with Venetoclax/Azacitidine Can be Safely Given after Venetoclax/FluBu2 RIC Allogeneic Transplantation for the Treatment of High Risk MDS/AML: Results of a Phase 1 Study

Jacqueline S. Garcia, Haesook T Kim, Jennifer Brock, H. Moses Murdock, Corey S. Cutler, Daniel J. DeAngelo, Christopher J. Gibson, Mahasweta Gooptu, Vincent Ho, John Koreth, Marlise R. Luskin, Sarah Nikiforow, Rizwan Romee, Roman M Shapiro, Richard M. Stone, Martha Wadleigh, Eric S. Winer, Michela Ansuinelli, Eliza Elliot, Geoffrey Fell, Hannah Karp, Jeremy Ryan, Anthony G. Letai, Coleman Lindsley, Robert J Soiffer, Joseph H. Antin, Fiona Loschi, Jerome Ritz
Journal: Blood
Blood (2022) 140 (Supplement 1): 917–919.
https://doi.org/10.1182/blood-2022-157611
Published: 2022