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Nathalie Javidi-Sharifi
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Journal Articles

Pharmacodynamic Analysis of Mcl-1 and RNA Pol II Ser2 Phosphorylation in Blasts from Patients with Relapsed or Refractory Acute Myeloid Leukemia Treated on a Phase 1 Study of Venetoclax Plus Voruciclib

Nathalie Javidi-Sharifi, Jeremy Zhang, Sandra Wiley, Richard G Ghalie, Alexey V. Danilov, Matthew S. Davids
Journal: Blood
Blood (2024) 144 (Supplement 1): 4147.
https://doi.org/10.1182/blood-2024-203689
Published: 2024
Journal Articles

A Phase 1 Study of the Oral CDK9 Inhibitor Voruciclib in Combination with Venetoclax in Relapsed/Refractory (R/R) Acute Myeloid Leukemia (AML)

Yesid Alvarado-Valero, Rachel J. Cook, Shira N. Dinner, Michael Keng, Kebede Begna, Sameem Abedin, MHD Monzr M. Al Malki, Vijaya Raj Bhatt, Nathalie Javidi-Sharifi, Prabhu Rajagopolan, Sandra Wiley, Richard G Ghalie, Matthew S. Davids
Journal: Blood
Blood (2024) 144 (Supplement 1): 2878.
https://doi.org/10.1182/blood-2024-198718
Published: 2024
Journal Articles

A Phase 1 Study of the Oral CDK9 Inhibitor Voruciclib in Relapsed/Refractory (R/R) B-Cell Lymphoma (NHL) or Acute Myeloid Leukemia (AML)

Matthew S Davids, Yesid Alvarado Valero, Catherine Diefenbach, Daniel N. Egan, Shira N. Dinner, Monzr M. Al Malki, Kebede Begna, Avyakta Kallam, Sameem Abedin, Rachel Cook, Nathalie Javidi-Sharifi, Edward Dominguez, Lu Miao, Richard G Ghalie, Alexey Danilov
Journal: Blood
Blood (2023) 142 (Supplement 1): 4286.
https://doi.org/10.1182/blood-2023-179577
Published: 2023
Journal Articles

Marrow Stromal Cells Secrete FGF2 in Exosomes, Providing Paracrine Protection for Leukemia Cells from Kinase Inhibitors

Elie Traer, MD PhD, Brian J. Druker, MD, Jakki Martinez, Nathalie Javidi-Sharifi, Isabel English, BA, Anupriya Agarwal, PhD, Jennifer Dunlap, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 306.
https://doi.org/10.1182/blood.V130.Suppl_1.306.306
Published: 2017
Journal Articles

Effective Combination of CPX-351 with FLT3 Inhibitors in AML Blasts Harboring the FLT3-ITD Mutation

David K. Edwards, V, BA, BS, Nathalie Javidi-Sharifi, Angela Rofelty, Claire Rosenfeld, Riley Roth-Carter, Paul Tardi, PhD, Lawrence Mayer, PhD, Jeffrey W. Tyner
Journal: Blood
Blood (2016) 128 (22): 5124.
https://doi.org/10.1182/blood.V128.22.5124.5124
Published: 2016
Journal Articles

FGF2 from Bone Marrow Stroma Protects Acute Myeloid Leukemia Cells from the FLT3 Inhibitor Quizartinib and Facilitates Acquisition of Resistance Mutations

Elie Traer, MD, Nathalie Javidi-Sharifi, Jacqueline Martinez, MS, Isabel English, Jennifer Dunlap, MD, Anupriya Agarwal, Tibor J. Kovacsovics, MD, Jeffrey W. Tyner, Melissa Wong, PhD, Brian J. Druker, MD
Journal: Blood
Blood (2016) 128 (22): 1080.
https://doi.org/10.1182/blood.V128.22.1080.1080
Published: 2016
Journal Articles

FGF2-Containing Exosomes Secreted from Bone Marrow Stromal Cells Protect Leukemia Cells from Tyrosine Kinase Inhibitors

Jacqueline Martinez, MS, Nathalie Javidi-Sharifi, Isabel English, Shelton A. Viola, MD, Danielle Jorgens, PhD, Brian J. Druker, MD, Elie Traer, MD PhD
Journal: Blood
Blood (2015) 126 (23): 2465.
https://doi.org/10.1182/blood.V126.23.2465.2465
Published: 2015
Journal Articles

GNB1 Activating Mutations Promote Myeloid and Lymphoid Neoplasms Targetable By Combined PI3K/mTOR Inhibition

Akinori Yoda, PhD, Guillaume Adelmant, PhD, Jerome Tamburini, MD PhD, Bjoern Chapuy, MD PhD, Nobuaki Shindoh, PhD, Yuka Yoda, MPh, Oliver Weigert, MD, Nadja Kopp, MA, Shuo-Chieh Wu, Sunhee S. Kim, Huiyun Liu, Trevor Tivey, Amanda L Christie, Kutlu G Elpek, Joseph Card, Kira Gritsman, MD PhD, Jason Gotlib, MD MS, Michael W. Deininger, Hideki Makishima, MD PhD, Shannon Turley, PhD, Nathalie Javidi-Sharifi, Jaroslaw P. Maciejewski, MD PhD, Scott J Rodig, MD PhD, Jeffrey W. Tyner, Jarrod A Marto, PhD, David M. Weinstock, MD, Andrew A. Lane, MD PhD
Journal: Blood
Blood (2014) 124 (21): 3567.
https://doi.org/10.1182/blood.V124.21.3567.3567
Published: 2014
Journal Articles

Ponatinib overcomes FGF2-mediated resistance in CML patients without kinase domain mutations

Elie Traer, Nathalie Javidi-Sharifi, Anupriya Agarwal, Jennifer Dunlap, Isabel English, Jacqueline Martinez, Jeffrey W. Tyner, Melissa Wong, Brian J. Druker
Journal: Blood
Blood (2014) 123 (10): 1516–1524.
https://doi.org/10.1182/blood-2013-07-518381
Published: 2014
Includes: Supplemental data
Journal Articles

FGF2 Promotes Resistance To Quizartinib In Vitro, and FGF2 Increases In The Marrow Of Patients Prior To Resistance

Elie Traer, MD, PhD, Nathalie Javidi-Sharifi, Anupriya Agarwal, Jennifer B Dunlap, MD, Isabel English, Jacqueline Martinez, Tibor J. Kovacsovics, MD, Jeffrey W. Tyner, Melissa Wong, PhD, Brian J. Druker
Journal: Blood
Blood (2013) 122 (21): 2541.
https://doi.org/10.1182/blood.V122.21.2541.2541
Published: 2013
Journal Articles

FGF2 Mediates Resistance In CML Patients In The Absence Of Kinase Domain Mutations, and Resistance Is Overcome By Ponatinib

Elie Traer, MD, PhD, Nathalie Javidi-Sharifi, Anupriya Agarwal, Jennifer B Dunlap, MD, Isabel English, Jacqueline Martinez, Jeffrey W. Tyner, Melissa Wong, PhD, Brian J. Druker
Journal: Blood
Blood (2013) 122 (21): 3983.
https://doi.org/10.1182/blood.V122.21.3983.3983
Published: 2013