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Alexey V. Danilov
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Journal Articles

T-bet suppresses proliferation of malignant B cells in chronic lymphocytic leukemia

Philipp M. Roessner, Isabelle Seufert, Vicente Chapaprieta, Ruparoshni Jayabalan, Hannah Briesch, Ramon Massoni-Badosa, Pavle Boskovic, Julian Benckendorff, Tobias Roider, Lavinia Arseni, Mariana Coelho, Supriya Chakraborty, Alicia M. Vaca, Mariela Sivina, Markus Muckenhuber, Sonia Rodriguez-Rodriguez, Alice Bonato, Sophie A. Herbst, Marc Zapatka, Clare Sun, Helene Kretzmer, Thomas Naake, Peter-Martin Bruch, Felix Czernilofsky, Elisa ten Hacken, Martin Schneider, Dominic Helm, Deyan Y. Yosifov, Joseph Kauer, Alexey V. Danilov, Moritz Bewarder, Kristina Heyne, Christof Schneider, Stephan Stilgenbauer, Adrian Wiestner, Jan-Philipp Mallm, Jan A. Burger, Dimitar G. Efremov, Peter Lichter, Sascha Dietrich, José I. Martin-Subero, Karsten Rippe, Martina Seiffert
Journal: Blood
Blood (2024) 144 (5): 510–524.
https://doi.org/10.1182/blood.2023021990
Published: 2024
Includes: Supplemental data
Journal Articles

Glofitamab stimulates immune cell infiltration of CNS tumors and induces clinical responses in secondary CNS lymphoma

James K. Godfrey, Lei Gao, Geoffrey Shouse, Joo Y. Song, Stacy Pak, Brian Lee, Bihong T. Chen, Avyakta Kallam, John H. Baird, Guido Marcucci, Lucy Ghoda, Stephanie Vauleon, Alexey V. Danilov, Alex F. Herrera, Larry W. Kwak, Lihua E. Budde
Journal: Blood
Blood (2024) 144 (4): 457–461.
https://doi.org/10.1182/blood.2024024168
Published: 2024
Includes: Supplemental data
Journal Articles

Cost-effectiveness of polatuzumab vedotin combined with chemoimmunotherapy in untreated diffuse large B-cell lymphoma

Clinical Trials & Observations
Swetha Kambhampati, Monica Saumoy, Yecheskel Schneider, Stacy Pak, Lihua Elizabeth Budde, Matthew G. Mei, Tanya Siddiqi, Leslie L. Popplewell, Yi-Ping Wen, Jasmine Zain, Stephen J. Forman, Larry W. Kwak, Steven T. Rosen, Alexey V. Danilov, Alex F. Herrera, Nikhil R. Thiruvengadam
Journal: Blood
Blood (2022) 140 (25): 2697–2708.
https://doi.org/10.1182/blood.2022016624
Published: 2022
Includes: Supplemental data
Journal Articles

Double Hit/Double Expressor Lymphomas: A Multicenter Analysis of Survival Outcomes with CD19-Directed CAR T-Cell Therapy

Joanna Zurko, Geoffrey Shouse, Pallawi Torka, Tamara K. Moyo, Jason T. Romancik, Imran A. Nizamuddin, Kaitlin Annunzio, Jieqi Liu, Stefan K. Barta, Robert Ferdman, Rahul Bhansali, Jonathon B. Cohen, Sayan Mullick Chowdhury, Nirav N. Shah, Elyse I. Harris, Vaishalee P. Kenkre, McKenzie Sorrell, Brian T. Hess, Deborah M. Stephens, Lindsey A. Fitzgerald, Thomas A. Ollila, Ishan Roy, Shuo Ma, Jane N. Winter, Barbara Pro, Jonathan Moreira, Leo I. Gordon, Alexey V Danilov, Andrew M. Evens, Narendranath Epperla, Reem Karmali
Journal: Blood
Blood (2022) 140 (Supplement 1): 375–377.
https://doi.org/10.1182/blood-2022-163438
Published: 2022
Journal Articles

Impact of Race and Social Determinants of Health on Outcomes in Patients with Aggressive B-Cell Lymphomas Treated with Chimeric Antigen Receptor T-Cell (CART) Therapy

Reem Karmali, Narendranath Epperla, Geoffrey Shouse, Jason T. Romancik, Tamara K. Moyo, Vaishalee P. Kenkre, Thomas A. Ollila, Lindsey A. Fitzgerald, Brian T. Hess, Andrew M. Evens, Ishan Roy, Joanna Zurko, Sayan Mullick Chowdhury, Kaitlin Annunzio, Robert Ferdman, Rahul Bhansali, Elyse I. Harris, McKenzie Sorrell, Jieqi Liu, Imran A. Nizamuddin, Shuo Ma, Jonathan Moreira, Jane N. Winter, Barbara Pro, Deborah M. Stephens, Alexey V Danilov, Nirav N. Shah, Jonathon B. Cohen, Stefan K. Barta, Pallawi Torka, Leo I. Gordon
Journal: Blood
Blood (2022) 140 (Supplement 1): 10955–10957.
https://doi.org/10.1182/blood-2022-160431
Published: 2022
Journal Articles

Phase 1b/2a Study of AZD4573 (CDK9i) and Acalabrutinib in Patients with Relapsed/Refractory Diffuse Large B-Cell Lymphoma (r/r DLBCL): Results from Dose-Escalation

Paolo Strati, Tae Min Kim, Alexey V Danilov, Chan Y. Cheah, Dok Hyun Yoon, Wojciech Jurczak, Shringi Sharma, Jeong Lim Yoon, Serena Arduini, Jamal Saeh, Richard F. Olsson, Gareth Gregory
Journal: Blood
Blood (2022) 140 (Supplement 1): 6656–6658.
https://doi.org/10.1182/blood-2022-165979
Published: 2022
Journal Articles

A Phase I Trial of PI3Kαδ Inhibitor Copanlisib in Combination with Nivolumab in Patients with Richter's Transformation (RT) or Transformed Non-Hodgkin Lymphoma (tNHL)

Geoffrey Shouse, Tanya Siddiqi, Leslie L. Popplewell, Alexandra Muir, Ivana Melgar, Kirsten Orand, Brandy Gonzalez, Sandrine Puverel, Lili Wang, Adam S Kittai, Lu Chen, Matthew S. Davids, Alexey V Danilov
Journal: Blood
Blood (2022) 140 (Supplement 1): 6633–6634.
https://doi.org/10.1182/blood-2022-160157
Published: 2022
Journal Articles

A Phase II Trial of Acalabrutinib in Combination with PI3Kδ Inhibitor Umbralisib and the Anti-CD20 Antibody Ublituximab (AU2) in Patients with Previously Untreated Mantle Cell Lymphoma (MCL)

Alexey V Danilov, Alexandra Muir, Ivana Melgar, Sandrine Puverel, Peter Sportelli, Hari P. Miskin, Lu Chen, Geoffrey Shouse
Journal: Blood
Blood (2022) 140 (Supplement 1): 3633–3634.
https://doi.org/10.1182/blood-2022-159805
Published: 2022
Journal Articles

Consensus Cachexia Criteria Are Independently Linked to Progression Free and Overall Survival in Multi-Site Analysis of Patients with Aggressive B-Cell Lymphomas Treated with CAR T-Cell Therapy

Ishan Roy, Narendranath Epperla, Geoffrey Shouse, Jason T. Romancik, Tamara K. Moyo, Vaishalee P. Kenkre, Thomas A. Ollila, Lindsey A. Fitzgerald, Brian T. Hess, Andrew M. Evens, Joanna Zurko, Sayan Mullick Chowdhury, Kaitlin Annunzio, Robert Ferdman, Rahul S. Bhansali, Elyse I. Harris, McKenzie Sorrell, Jieqi Liu, Imran A. Nizamuddin, Jonathan Moreira, Shuo Ma, Jane N. Winter, Barbara Pro, Deborah M. Stephens, Alexey V Danilov, Nirav N. Shah, Jonathon B. Cohen, Stefan K. Barta, Pallawi Torka, Leo I. Gordon, Reem Karmali
Journal: Blood
Blood (2022) 140 (Supplement 1): 2416–2418.
https://doi.org/10.1182/blood-2022-163822
Published: 2022
Journal Articles

Targeting Sumoylation with Subasumstat (TAK-981), a Selective Inhibitor of SUMO-Activating Enzyme (SAE), Induces Mitochondrial Dysfunction in Preclinical Models of Non-Hodgkin Lymphoma (NHL)

Tingting Liu, Vi Lam, Elana Thieme, Olga Danilova, Nur Bruss, Lapo Alinari, Jeffrey W. Tyner, Stephen E. Kurtz, Zheng Xia, Alexey V Danilov
Journal: Blood
Blood (2022) 140 (Supplement 1): 6016–6017.
https://doi.org/10.1182/blood-2022-159691
Published: 2022
Journal Articles

Impact of a Validated Composite Comorbidity Score on Outcomes in Patients Treated with CAR T-Cell Therapy for Diffuse Large B Cell Lymphoma (DLBCL): A Multicenter Real-World Evidence (RWE) Study

Geoffrey Shouse, Andy Kaempf, Max J. Gordon, David Yashar, Audrey M. Sigmund, Gordon Smilnak, Steven M. Bair, Agrima Mian, Lindsey A. Fitzgerald, Amneet Bajwa, Samantha Jaglowski, Neil Bailey, Mazyar Shadman, Krish Patel, Deborah M. Stephens, Manali Kamdar, Brian T. Hill, Jordan Gauthier, Reem Karmali, Loretta J. Nastoupil, Adam S Kittai, Alexey V Danilov
Journal: Blood
Blood (2022) 140 (Supplement 1): 2048–2050.
https://doi.org/10.1182/blood-2022-169872
Published: 2022
Journal Articles

A Phase 1b Study of IDH Inhibition with Enasidenib and MEK Inhibition with Cobimetinib in Patients with Relapsed or Refractory Acute Myeloid Leukemia Who Have Co-Occurring IDH2 and RAS Signaling Gene Mutations

Brian J Ball, Eytan Stein, Marjorie Robbins, Jianying Zhang, Ross L. Levine, Timothy Synold, Anthony S. Stein, Guido Marcucci, Yilun Liu, Alexey V Danilov
Journal: Blood
Blood (2022) 140 (Supplement 1): 11761–11762.
https://doi.org/10.1182/blood-2022-170820
Published: 2022
Journal Articles

Association of Non-Hodgkin Lymphoma (NHL), Comorbidity and Death Due to Other Cancers in 30,000 Older Adults from SEER-Medicare

Max J. Gordon, Zhigang Duan, Hui Zhao, Loretta J. Nastoupil, Alessandra Ferrajoli, Alexey V Danilov, Sharon Giordano
Journal: Blood
Blood (2022) 140 (Supplement 1): 8034–8035.
https://doi.org/10.1182/blood-2022-163472
Published: 2022
Journal Articles

Disrupting MGA-MYC Driven Metabolic Reprogramming in Richter's Syndrome Pre-Clinical Models Via Novel Therapeutic Approaches

Prajish Iyer, Bo Zhang, Tingting Liu, Meiling Jin, Kevyn Hart, Joo Y. Song, Wing C Chan, Tanya Siddiqi, Alexey V Danilov, Steve T Rosen, Lili Wang
Journal: Blood
Blood (2022) 140 (Supplement 1): 9842–9843.
https://doi.org/10.1182/blood-2022-162664
Published: 2022
Journal Articles

NX-2127-001, a First-in-Human Trial of NX-2127, a Bruton's Tyrosine Kinase-Targeted Protein Degrader, in Patients with Relapsed or Refractory Chronic Lymphocytic Leukemia and B-Cell Malignancies

Anthony R. Mato, William G. Wierda, Weiyun Z. Ai, Ian W. Flinn, Michael Tees, Manish R. Patel, Krish Patel, Susan O'Brien, David A. Bond, Lindsey E. Roeker, Tanya Siddiqi, Michael L. Wang, Clare Sun, Omar Abdel-Wahab, Amanda Schwab, May Tan, Erin Meredith, Melissa A. Gessner, Su Young Kim, Adrian Wiestner, Alexey V Danilov
Journal: Blood
Blood (2022) 140 (Supplement 1): 2329–2332.
https://doi.org/10.1182/blood-2022-164772
Published: 2022
Journal Articles

Cost-effectiveness of second-line axicabtagene ciloleucel in relapsed refractory diffuse large B-cell lymphoma

Clinical Trials & Observations
Swetha Kambhampati, Monica Saumoy, Yecheskel Schneider, Steve Serrao, Pejman Solaimani, Lihua Elizabeth Budde, Matthew G. Mei, Leslie L. Popplewell, Tanya Siddiqi, Jasmine Zain, Stephen J. Forman, Larry W. Kwak, Steven T. Rosen, Alexey V. Danilov, Alex F. Herrera, Nikhil R. Thiruvengadam
Journal: Blood
Blood (2022) 140 (19): 2024–2036.
https://doi.org/10.1182/blood.2022016747
Published: 2022
Includes: Supplemental data
Journal Articles

Immunity in CLL: corrupt at inception?

Alexey V. Danilov
Journal: Blood
Blood (2022) 139 (14): 2104–2105.
https://doi.org/10.1182/blood.2022015413
Published: 2022
Journal Articles

MGA deletion Leads to Richter's Transformation Via NME1

Prajish Iyer, Bo Zhang, Tingting Liu, Meiling Jin, Kevyn Hart, Joo Y. Song, John Chan, Raju Pillai, Tanya Siddiqi, Alexey V. Danilov, Steven T. Rosen, Lili Wang
Journal: Blood
Blood (2021) 138 (Supplement 1): 252.
https://doi.org/10.1182/blood-2021-148953
Published: 2021
Journal Articles

Outcomes and Treatment Patterns in Patients with Aggressive B-Cell Lymphoma after Failure of Anti-CD19 CAR T-Cell Therapy

Joanna C. Zurko, Narendranath Epperla, Imran Nizamuddin, Pallawi Torka, Kevin A. David, Thomas A. Ollila, Brian T. Hess, Jonathon B. Cohen, Robert Ferdman, Jieqi Liu, Sayan Mullick Chowdhury, Kaitlyn O'Shea, Jason Romancik, Rahul Bhansali, Elyse Harris, Mckenzie Sorrell, Rebecca Masel, Lindsey Fitzgerald, Carlos Galvez, Shuo Ma, Jane N. Winter, Barbara Pro, Leo I. Gordon, Alexey V. Danilov, Deborah M. Stephens, Nirav N. Shah, Geoffrey Shouse, Vaishalee P. Kenkre, Stefan K. Barta, Reem Karmali
Journal: Blood
Blood (2021) 138 (Supplement 1): 884.
https://doi.org/10.1182/blood-2021-147433
Published: 2021
Journal Articles

A Large Multicenter Real-World Evidence (RWE) Analysis of Autoimmune (AI) Diseases and Lymphoma: Histologic Associations, Disease Characteristics, Survival, and Prognostication

Jordan Carter, Adam J. Olszewski, Tatyana A. Feldman, Reem Karmali, Jean L. Koff, Sabarish Ayyappan, Matthew A. Lunning, Shazia Nakohda, Nadia Khan, Aryeh Pelcovits, Jason Lofters, Timothy Seijung Oh, Colin Burke O'Leary, Kittika Poonsombudlert, Carman Tong, Elaine Kuhn, Mingen Liu, Andrea Anampa-Guzman, Megha Shalavadi, Colin Thomas, Melissa Kives, Ning C. Dong, Alexander Hershey, Neil Palmisiano, Alexey V. Danilov, Francisco J. Hernandez-Ilizaliturri, Stefan K. Barta, Frederick Lansigan, Kerry J. Savage, Andrew M. Evens
Journal: Blood
Blood (2021) 138 (Supplement 1): 50.
https://doi.org/10.1182/blood-2021-149728
Published: 2021