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Peter-Martin Bruch
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Journal Articles

CD20-bispecific antibodies improve response to CD19-CAR T cells in lymphoma in vitro and CLL in vivo models

Brief Report
Berit J. Brinkmann, Alessia Floerchinger, Christina Schniederjohann, Tobias Roider, Mariana Coelho, Norman Mack, Peter-Martin Bruch, Nora Liebers, Sarah Dötsch, Dirk H. Busch, Michael Schmitt, Frank Neumann, Philipp M. Roessner, Martina Seiffert, Sascha Dietrich
Journal: Blood
Blood (2024) 144 (7): 784–789.
https://doi.org/10.1182/blood.2023022682
Published: 2024
Includes: Supplemental data
Journal Articles

T-bet suppresses proliferation of malignant B cells in chronic lymphocytic leukemia

Philipp M. Roessner, Isabelle Seufert, Vicente Chapaprieta, Ruparoshni Jayabalan, Hannah Briesch, Ramon Massoni-Badosa, Pavle Boskovic, Julian Benckendorff, Tobias Roider, Lavinia Arseni, Mariana Coelho, Supriya Chakraborty, Alicia M. Vaca, Mariela Sivina, Markus Muckenhuber, Sonia Rodriguez-Rodriguez, Alice Bonato, Sophie A. Herbst, Marc Zapatka, Clare Sun, Helene Kretzmer, Thomas Naake, Peter-Martin Bruch, Felix Czernilofsky, Elisa ten Hacken, Martin Schneider, Dominic Helm, Deyan Y. Yosifov, Joseph Kauer, Alexey V. Danilov, Moritz Bewarder, Kristina Heyne, Christof Schneider, Stephan Stilgenbauer, Adrian Wiestner, Jan-Philipp Mallm, Jan A. Burger, Dimitar G. Efremov, Peter Lichter, Sascha Dietrich, José I. Martin-Subero, Karsten Rippe, Martina Seiffert
Journal: Blood
Blood (2024) 144 (5): 510–524.
https://doi.org/10.1182/blood.2023021990
Published: 2024
Includes: Supplemental data
Journal Articles

Improving Anti-Tumor Efficacy of CAR T-Cell Therapy for Acute Myeloid Leukemia (AML): Results from a Multi-Drug Interaction Screening Approach

Julia M. Unglaub, Berit Brinkmann, Qian Chen, David Sedloev, Peter-Martin Bruch, Carolin Kolb, Volker Eckstein, Yi Liu, Anita Schmitt, Simon Raffel, Michael Schmitt, Carsten Müller-Tidow, Junyan Lu, Sascha Dietrich, Tim Sauer
Journal: Blood
Blood (2023) 142 (Supplement 1): 5969.
https://doi.org/10.1182/blood-2023-181251
Published: 2023
Journal Articles

Venetoclax synergizes with gilteritinib in FLT3 wild-type high-risk acute myeloid leukemia by suppressing MCL-1

Maike Janssen, Christina Schmidt, Peter-Martin Bruch, Maximilian F. Blank, Christian Rohde, Alexander Waclawiczek, Daniel Heid, Simon Renders, Stefanie Göllner, Lisa Vierbaum, Birgit Besenbeck, Sophie A. Herbst, Mareike Knoll, Carolin Kolb, Adriana Przybylla, Katharina Weidenauer, Anne Kathrin Ludwig, Margarete Fabre, Muxin Gu, Richard F. Schlenk, Friedrich Stölzel, Martin Bornhäuser, Christoph Röllig, Uwe Platzbecker, Claudia Baldus, Hubert Serve, Tim Sauer, Simon Raffel, Caroline Pabst, George Vassiliou, Binje Vick, Irmela Jeremias, Andreas Trumpp, Jeroen Krijgsveld, Carsten Müller-Tidow, Sascha Dietrich
Journal: Blood
Blood (2022) 140 (24): 2594–2610.
https://doi.org/10.1182/blood.2021014241
Published: 2022
Includes: Supplemental data
Journal Articles

Humoral and cellular responses after COVID-19 vaccination in anti-CD20-treated lymphoma patients

Clinical Trials & Observations
Nora Liebers, Claudius Speer, Louise Benning, Peter-Martin Bruch, Isabelle Kraemer, Julia Meissner, Paul Schnitzler, Hans-Georg Kräusslich, Peter Dreger, Carsten Mueller-Tidow, Isabel Poschke, Sascha Dietrich
Journal: Blood
Blood (2022) 139 (1): 142–147.
https://doi.org/10.1182/blood.2021013445
Published: 2022
Includes: Supplemental data
Journal Articles

Proteogenomic Subtyping of Chronic Lymphocytic Leukemia Identifies a Novel Poor Outcome Subgroup with a Distinct Drug Response Profile

Sophie A. Herbst, MSc, Mattias Vesterlund, Rozbeh Jafari, PhD, Ioannis Siavelis, Matthias Stahl, Eva Schitter, Alexander J. Helmboldt, Murat Iskar, Nora Liebers, MD, Felix Czernilofsky, Tobias Roider, MD, Peter-Martin Bruch, Junyan Lu, Sarah Richter, Georgios Mermelekas, Husen Muhammad Umer, Mareike Knoll, Carolin Kolb, Angela Lenze, Xiaofang Cao, Cecilia Österholm-Corbascio, Sebastian Scheinost, Matthias Ganzinger, Larry Mansouri, PhD, Katharina Kriegsmann, MD, Mark Kriegsmann, MD, Carsten Mueller-Tidow, MD, Peter Dreger, MD, Simon Anders, PhD, Marc Zapatka, Marco Herling, MD, Richard Rosenquist, MD, Stephan Stilgenbauer, MD, Thorsten Zenz, Wolfgang Huber, PhD, Eugen Tausch, MD, Janne Lehtiö, Sascha Dietrich, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 10–11.
https://doi.org/10.1182/blood-2020-137528
Published: 2020
Journal Articles

Ex-Vivo Drug Response Profiling for Tailoring Treatment in Hematologic Malignancies: The Prospective Non-Interventional SMART-Trial

Nora Liebers, Peter-Martin Bruch, Agnes Gambietz, Holly Giles, BA, Junyan Lu, PhD, Mareike Knoll, Carolin Kolb, Peter Dreger, Carsten Mueller-Tidow, MD, Wolfgang Huber, PhD, Axel Benner, Thorsten Zenz, MD, Sascha Dietrich, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 376.
https://doi.org/10.1182/blood-2019-125324
Published: 2019
Journal Articles

Systematic Investigation of Microenvironmental Drug Resistance Mechanisms in Chronic Lymphocytic Leukemia

Peter-Martin Bruch, Holly Giles, BA, Carolin Kolb, Sophie Rabe, MSc, Tobias Roider, MD, Mareike Knoll, Mark Kriegsmann, MD, Katharina Kriegsmann, MD, Christiane Zgorzelski, Sebastian Scheinost, Lena Wagner, Carsten Müller-Tidow, MD, Thorsten Zenz, MD, Wolfgang Huber, PhD, Sascha Dietrich, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3363.
https://doi.org/10.1182/blood-2019-128392
Published: 2019
Journal Articles

The Influence of the Bone Marrow Niche on Drug Response Phenotypes of Blood Cancers

Sophie Rabe, MSc, Eva Schitter, Tobias Roider, Peter-Martin Bruch, Carolin Kolb, Marta Stolarczyk, Jennifer Hüllein, Junyan Lu, Christof von Kalle, Christoph Lutz, Peter Dreger, Carsten Mueller-Tidow, Thorsten Zenz, MD, Wolfgang Huber, Sascha Dietrich, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 262.
https://doi.org/10.1182/blood-2018-99-116053
Published: 2018