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Journal Articles

Somatic TET2 Mutations Prime the Immune System for Response to Immune Checkpoint Blockade

Robert Vanner, Andy G.X. Zeng, Michelle Chan-Seng-Yue, Suraj Bansal, Elisa Donato, Liqing Jin, Sofia Genta, Enrique Sanz Garcia, Steven M. Chan, Andreas Trumpp, John E. Dick

Blood (2023) 142 (Supplement 1): 2689.

https://doi.org/10.1182/blood-2023-177740

Published: 2023

Journal Articles

A noncanonical enzymatic function of PIWIL4 maintains genomic integrity and leukemic growth in AML

Blood (2023) 142 (1): 90–105.

https://doi.org/10.1182/blood.2022018651

Published: 2023

Includes: Supplemental data

Journal Articles

Venetoclax synergizes with gilteritinib in FLT3 wild-type high-risk acute myeloid leukemia by suppressing MCL-1

Blood (2022) 140 (24): 2594–2610.

https://doi.org/10.1182/blood.2021014241

Published: 2022

Includes: Supplemental data

Journal Articles

Frequent Whole Blood Donations Select for DNMT3A variants Mediating Enhanced Response to Erythropoietin

Darja Karpova, Hector Huerga Encabo, Elisa Donato, Iuliia Kotova, Silvia Calderazzo, Aino-Maija Leppä, Panten Jasper, Adriana Przybylla, Erhard Seifried, Annette Kopp-Schneider, Terrence N Wong, Dominique Bonnet, Halvard Bonig, Andreas Trumpp

Blood (2022) 140 (Supplement 1): 8605–8606.

https://doi.org/10.1182/blood-2022-167821

Published: 2022

Journal Articles

Exploring Genetic and Non-Genetic Changes Driving Tumor Evolution in CK-AML at Single-Cell Resolution

Aino-Maija Leppä, Karen Grimes, Hyobin Jeong, Tobias Boch, Darja Karpova, Florian Grünschläger, Anna Jauch, Anna Dolnik, Bernardo Rodriguez-Martin, Lars Bullinger, Alwin Krämer, Ashley D Sanders, Jan O Korbel, Andreas Trumpp

Blood (2022) 140 (Supplement 1): 9170–9172.

https://doi.org/10.1182/blood-2022-166007

Published: 2022

Journal Articles

Macs - a Leukemic Stem Cell- Based Predictor of Clinical Response to Venetoclax and Other BH3 Mimetics for Acute Myeloid Leukemia

Simon Renders, Alexander Waclawiczek, Aino-Maija Leppä, Cecilia Reyneri, Barbara Betz, Karolin Stumpf, Maike Janssen, Julia M. Unglaub, Elisa Donato, Rabia Shahswar, Simon Raffel, Michael Heuser, Richard F. Schlenk, Michael Hundemer, Tim Sauer, Carsten Müller-Tidow, Andreas Trumpp

Blood (2022) 140 (Supplement 1): 2023–2024.

https://doi.org/10.1182/blood-2022-164831

Published: 2022

Journal Articles

Driving differentiation: targeting APA in AML

Pia Sommerkamp, Andreas Trumpp

Blood (2022) 139 (3): 317–319.

https://doi.org/10.1182/blood.2021013814

Published: 2022

Journal Articles

Leukemic Stem Cells of Monocytic AMLs Are Not-Resistant to BCL-2 Inhibition

Simon Renders, Aino-Maija Leppä, Alexander Waclawiczek, Maike Janssen, Elisa Donato, Cecilia Reyneri, Julia M. Unglaub, Michael Hundemer, Richard F. Schlenk, Simon Raffel, Carsten Müller-Tidow, Tim Sauer, Andreas Trumpp

Blood (2021) 138 (Supplement 1): 3469.

https://doi.org/10.1182/blood-2021-149781

Published: 2021

Journal Articles

Mouse multipotent progenitor 5 cells are located at the interphase between hematopoietic stem and progenitor cells

Pia Sommerkamp, Mari Carmen Romero-Mulero, Andreas Narr, Luisa Ladel, Lucie Hustin, Katharina Schönberger, Simon Renders, Sandro Altamura, Petra Zeisberger, Karin Jäcklein, Daniel Klimmeck, Alejo Rodriguez-Fraticelli, Fernando D. Camargo, Leïla Perié, Andreas Trumpp, Nina Cabezas-Wallscheid

Blood (2021) 137 (23): 3218–3224.

https://doi.org/10.1182/blood.2020007876

Published: 2021

Includes: Supplemental data

Journal Articles

Adult blood stem cell localization reflects the abundance of reported bone marrow niche cell types and their combinations

Konstantinos D. Kokkaliaris, Leo Kunz, Nina Cabezas-Wallscheid, Constantina Christodoulou, Simon Renders, Fernando Camargo, Andreas Trumpp, David T. Scadden, Timm Schroeder

Blood (2020) 136 (20): 2296–2307.

https://doi.org/10.1182/blood.2020006574

Published: 2020

Includes: Multimedia, Supplemental data

Journal Articles

Quantitative proteomics reveals specific metabolic features of acute myeloid leukemia stem cells

Blood (2020) 136 (13): 1507–1519.

https://doi.org/10.1182/blood.2019003654

Published: 2020

Includes: Supplemental data

Journal Articles

Characteristic Amino Acid and Energy Metabolism in AML Stem Cells As Revealed By Quantitative Multiplex Proteomics

Simon Raffel, MD, Jenny Hansson, Mattia Falcone, Christoph Lutz, Oliver Bischel, MD, Anthony D Ho, Jeroen Krijgsveld, Andreas Trumpp, Prof, PhD

Blood (2018) 132 (Supplement 1): 2780.

https://doi.org/10.1182/blood-2018-99-117046

Published: 2018

Journal Articles

Combined Single-Cell and Spatial Transcriptomics to Deconvolute the Hematopoietic Stem Cell Niche

Simon Haas, PhD, Chiara Baccin, Jude Al-Sabah, Lars Velten, PhD, Steinmetz Lars, PhD, Andreas Trumpp, Prof, PhD

Blood (2018) 132 (Supplement 1): 876.

https://doi.org/10.1182/blood-2018-99-118479

Published: 2018

Journal Articles

Absence of NKG2D Ligands Defines Human Acute Myeloid Leukaemia Stem Cells and Mediates Their Immune Evasion

Blood (2018) 132 (Supplement 1): 769.

https://doi.org/10.1182/blood-2018-99-118047

Published: 2018

Journal Articles

The Netrin-1 - Neogenin Axis Regulates Hematopoietic Stem Cell Dormancy and Function with Implications for Stem Cell Ageing

Simon Renders, Pia Sommerkamp, Jasper Panten, Luisa Ladel, Katharina Schönberger, Daniel Klimmeck, PhD, Nina Cabezas-Wallscheid, PhD, Andreas Trumpp, Prof, PhD

Blood (2018) 132 (Supplement 1): 637.

https://doi.org/10.1182/blood-2018-99-118152

Published: 2018

Journal Articles

A Stem Cell-Based Epigenetic Memory Mediates Interferon Response-Heterogeneity within the Hematopoietic System

Simon Haas, PhD, Christoph Hirche, PhD, Alexandra Schnell, Can Sönmezer, Jens Langstein, Stephan Wurzer, PhD, Marc Thier, PhD, Sandra Blaszkiewicz, Franziska Pilz, Michael D. Milsom, PhD, Andreas Trumpp, Prof, PhD, Daniel Lipka, MD, Ulrich Kalinke, Prof, PhD, Marieke A. G. Essers, PhD

Blood (2017) 130 (Supplement 1): 634.

https://doi.org/10.1182/blood.V130.Suppl_1.634.634

Published: 2017

Journal Articles

Branched Chain Amino Acid Catabolism Restricts Alpha-Ketoglutarate Levels Resembling IDH mut -Driven DNA Hypermethylation in AML Stem Cells

Blood (2017) 130 (Supplement 1): 472.

https://doi.org/10.1182/blood.V130.Suppl_1.472.472

Published: 2017

Journal Articles

A Cluster of Enhancer Modules Directs Differential Myc Expression Along the Normal and Leukemic Hematopoietic Stem Cell Hierarchies

Carsten Bahr, MSc, Lisa von Paleske, PhD, Veli Vural Uslu, PhD, Silvia Remeseiro, PhD, Naoya Takayama, MD PhD, Stanley W.K. Ng, Alex Murison, PhD, Katja Langenfeld, Massimo Petretich, PhD, Roberta Scognamiglio, PhD, Petra Zeisberger, Amelie Benk, PhD, Ido Amit, PhD, Peter W. Zandstra, PhD, John E. Dick, PhD, Mathieu Lupien, PhD, Andreas Trumpp, Prof, PhD, Francois Spitz, PhD

Blood (2017) 130 (Supplement 1): 1150.

https://doi.org/10.1182/blood.V130.Suppl_1.1150.1150

Published: 2017

Journal Articles

Transition out of HSC Dormancy By a Continuous Upregulation of Metabolism Is Controlled Via Dietary Vitamin A/ Retinoic Acid Signaling

Blood (2016) 128 (22): LBA-4.

https://doi.org/10.1182/blood.V128.22.LBA-4.LBA-4

Published: 2016

Journal Articles

Mutational hierarchies in myelodysplastic syndromes dynamically adapt and evolve upon therapy response and failure

Blood (2016) 128 (9): 1246–1259.

https://doi.org/10.1182/blood-2015-11-679167

Published: 2016

Includes: Supplemental data

NARROW

Somatic TET2 Mutations Prime the Immune System for Response to Immune Checkpoint Blockade

A noncanonical enzymatic function of PIWIL4 maintains genomic integrity and leukemic growth in AML

Venetoclax synergizes with gilteritinib in FLT3 wild-type high-risk acute myeloid leukemia by suppressing MCL-1

Frequent Whole Blood Donations Select for DNMT3A variants Mediating Enhanced Response to Erythropoietin

Exploring Genetic and Non-Genetic Changes Driving Tumor Evolution in CK-AML at Single-Cell Resolution

Macs - a Leukemic Stem Cell- Based Predictor of Clinical Response to Venetoclax and Other BH3 Mimetics for Acute Myeloid Leukemia

Driving differentiation: targeting APA in AML

Leukemic Stem Cells of Monocytic AMLs Are Not-Resistant to BCL-2 Inhibition

Mouse multipotent progenitor 5 cells are located at the interphase between hematopoietic stem and progenitor cells

Adult blood stem cell localization reflects the abundance of reported bone marrow niche cell types and their combinations

Quantitative proteomics reveals specific metabolic features of acute myeloid leukemia stem cells

Characteristic Amino Acid and Energy Metabolism in AML Stem Cells As Revealed By Quantitative Multiplex Proteomics

Combined Single-Cell and Spatial Transcriptomics to Deconvolute the Hematopoietic Stem Cell Niche

Absence of NKG2D Ligands Defines Human Acute Myeloid Leukaemia Stem Cells and Mediates Their Immune Evasion

The Netrin-1 - Neogenin Axis Regulates Hematopoietic Stem Cell Dormancy and Function with Implications for Stem Cell Ageing

A Stem Cell-Based Epigenetic Memory Mediates Interferon Response-Heterogeneity within the Hematopoietic System

Branched Chain Amino Acid Catabolism Restricts Alpha-Ketoglutarate Levels Resembling IDH mut -Driven DNA Hypermethylation in AML Stem Cells

A Cluster of Enhancer Modules Directs Differential Myc Expression Along the Normal and Leukemic Hematopoietic Stem Cell Hierarchies

Transition out of HSC Dormancy By a Continuous Upregulation of Metabolism Is Controlled Via Dietary Vitamin A/ Retinoic Acid Signaling

Mutational hierarchies in myelodysplastic syndromes dynamically adapt and evolve upon therapy response and failure

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ASH Publications

American Society of Hematology

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ASH Publications

American Society of Hematology

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