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Journal Articles

Is Allogeneic Hematopoietic Stem Cell Transplant (HCT) in First Remission Beneficial to Acute Myeloid Leukemia (AML) Patients with Isocitrate Dehydrogenase(IDH) Mutations?

Ayman Sayyed, Taehyung Simon Kim, Silvia Park, Jae-Sook Ahn, Aly Karsan, Marie-France Gagnon, Julie Bergeron, Hyeoung-Joon Kim, Heeje Kim, David Sanford, Andre C. Schuh, Dennis Dong Hwan Kim

Blood (2023) 142 (Supplement 1): 4960.

https://doi.org/10.1182/blood-2023-191113

Published: 2023

Journal Articles

Acute Myeloid Leukemia (AML) Patients with Myelodysplasia (MDS) Related-Gene Mutations in First Complete Remission (CR1) Found to Have Benefit from Allogeneic Hematopoietic Stem Cell Transplant (HCT)

Ayman Sayyed, Taehyung Simon Kim, Silvia Park, Jae-Sook Ahn, Aly Karsan, Marie-France Gagnon, Julie Bergeron, Hee-Je Kim, Hyeoung-Joon Kim, David Sanford, Andre C. Schuh, Dennis Dong Hwan Kim

Blood (2023) 142 (Supplement 1): 4954.

https://doi.org/10.1182/blood-2023-191011

Published: 2023

Journal Articles

The Presence of Somatic Mutations on Specific Pathways Such As Chromatin Modifier, Spliceosome, and Myeloid Transcription Factor at Diagnosis Was Found to Have Benefit from Allogeneic Hematopoietic Stem Cell Transplantation (HCT) in 1,228 Patients with Acute Myeloid Leukemia in First Complete Remission (CR1)

Ayman Sayyed, Taehyung Simon Kim, Silvia Park, Jae-Sook Ahn, Aly Karsan, Marie-France Gagnon, Julie Bergeron, Hyeoung-Joon Kim, Heeje Kim, David Sanford, Andre C. Schuh, Dennis Dong Hwan Kim

Blood (2023) 142 (Supplement 1): 4949.

https://doi.org/10.1182/blood-2023-190545

Published: 2023

Journal Articles

A noncanonical enzymatic function of PIWIL4 maintains genomic integrity and leukemic growth in AML

Blood (2023) 142 (1): 90–105.

https://doi.org/10.1182/blood.2022018651

Published: 2023

Includes: Supplemental data

Journal Articles

Loss of FBXO11 Function Establishes a Stem Cell Program in Acute Myeloid Leukemia through Dysregulation of the Mitochondrial Protease LONP1

Angela Mo, Hayle Kincross, Xuan Wang, Linda Ya-Ting Chang, Gerben Duns, Harwood Kwan, Tammy Lau, Rod Docking, Se-Wing Grace Cheng, Shujun Huang, Nadia Gharaee, Elijah Willie, Jihong Jiang, Jeremy Parker, Josh Bridgers, Gregg Morin, Aly Karsan

Blood (2022) 140 (Supplement 1): 8688–8689.

https://doi.org/10.1182/blood-2022-170689

Published: 2022

Journal Articles

Relapse Timing Is Associated with Distinct Evolutionary Dynamics and Response to Salvage Therapy in DLBCL

Blood (2022) 140 (Supplement 1): 1310–1312.

https://doi.org/10.1182/blood-2022-160187

Published: 2022

Journal Articles

Meis1 Establishes the Pre-Hemogenic Endothelial State Prior to Runx1 Expression

Grace Cole, Patrick Coulombe, Amanda Fentiman, Jeremy Parker, Eric Yung, Lemlem Degefie, Patrick Lac, Maggie Ling, Derek Tam, R. Keith Humphries, Aly Karsan

Blood (2022) 140 (Supplement 1): 2857–2858.

https://doi.org/10.1182/blood-2022-170397

Published: 2022

Journal Articles

Chromatin Architecture Protein CTCF Plays a Role in Determining 5-Azacytidine Response of Leukemic Cells By Potentially Regulating Hoxb Genes

Aparna Gopal, Derek Tam, Ryan J. Stubbins, Kieran O'Neill, Marion Shadbolt, Deborah Deng, Rena Buckstein, Aly Karsan

Blood (2022) 140 (Supplement 1): 5850–5851.

https://doi.org/10.1182/blood-2022-170674

Published: 2022

Journal Articles

Inflammation and myeloid malignancy: quenching the flame

Ryan J. Stubbins, Uwe Platzbecker, Aly Karsan

Blood (2022) 140 (10): 1067–1074.

https://doi.org/10.1182/blood.2021015162

Published: 2022

Journal Articles

Elucidating the Importance and Regulation of Key Enhancers for Human MEIS1 Expression

Xining Yang, Ping Xiang, Leo Escano, Ishpreet Dhillon, Edith Schneider, Jack Clemans-Gibbon, Wei Wei, Jasper Wong, Simon Xufeng Wang, Gregg Morin, Pamela A Hoodless, Martin Hirst, Aly Karsan, Florian Kuchenbauer, R. Keith Humphries, Arefeh Rouhi

Blood (2021) 138 (Supplement 1): 3302.

https://doi.org/10.1182/blood-2021-151467

Published: 2021

Journal Articles

Elucidating the Mechanisms of Leukemogenesis Driven By FBXO11 Depletion

Angela Mo, Linda Ya-Ting Chang, Gerben Duns, Xuan Wang, Gregg Morin, Tammy Lau, Rod Docking, Shane Colborne, Se-Wing Grace Cheng, Shujun Huang, Hayle Kincross, Nadia Gharaee, Elijah Willie, Jihong Jiang, Jeremy Parker, Aly Karsan

Blood (2021) 138 (Supplement 1): 3328.

https://doi.org/10.1182/blood-2021-145384

Published: 2021

Journal Articles

Single-Cell Profiling Reveals Clinically Relevant Evolutionary Trajectories and Alternate Biologies in Human Follicular Lymphoma

Blood (2021) 138 (Supplement 1): 450.

https://doi.org/10.1182/blood-2021-153237

Published: 2021

Journal Articles

TIRAP Drives Marrow Failure through an Ifnγ-Hmgb1 Axis That Disrupts the Endothelial Niche

Aparna Gopal, Rawa Ibrahim, Megan Fuller, Patricia Umlandt, Jeremy Parker, Jessica Tran, Linda Ya-Ting Chang, Jeff Lam, Jenny Li, Melody Lu, Aly Karsan

Blood (2021) 138 (Supplement 1): 2169.

https://doi.org/10.1182/blood-2021-149245

Published: 2021

Journal Articles

SF3B1 -mutant MDS as a distinct disease subtype: a proposal from the International Working Group for the Prognosis of MDS

Blood (2020) 136 (2): 157–170.

https://doi.org/10.1182/blood.2020004850

Published: 2020

Journal Articles

Altered microRNA expression links IL6 and TNF-induced inflammaging with myeloid malignancy in humans and mice

Jennifer M. Grants, Joanna Wegrzyn, Tony Hui, Kieran O’Neill, Marion Shadbolt, David J. H. F. Knapp, Jeremy Parker, Yu Deng, Aparna Gopal, T. Roderick Docking, Megan Fuller, Jenny Li, Mark Boldin, Connie J. Eaves, Martin Hirst, Aly Karsan

Blood (2020) 135 (25): 2235–2251.

https://doi.org/10.1182/blood.2019003105

Published: 2020

Includes: Supplemental data

Journal Articles

Resistance to Lenalidomide in Del(5q) MDS Is Mediated By Inhibition of Drug-Induced Megakaryocytic Differentiation

Sergio Martinez-Høyer, PhD, Angela Mo, Deborah Deng, Jihong Jiang, Rod Docking, MSc, Jenny Li, Simon Chan, Patricia Umlandt, Megan Fuller, Martin Jädersten, Eva Hellström-Lindberg, MD PhD, Uwe Platzbecker, Jeremy Parker, PhD, Aly Karsan, MD

Blood (2018) 132 (Supplement 1): 176.

https://doi.org/10.1182/blood-2018-176

Published: 2018

Journal Articles

Outcomes of Patients with Low Variant Allele Fraction JAK2V617F : A 5-Year Retrospective Analysis

Wasithep Limvorapitak, MD, Jeremy Parker, PhD, Lynda Foltz, MD FRCPC, Aly Karsan, MD

Blood (2018) 132 (Supplement 1): 4286.

https://doi.org/10.1182/blood-2018-99-111592

Published: 2018

Journal Articles

Synthetic De Novo Modeling of Human T-Cell Acute Lymphoblastic Leukemia Reveals HOXB Genes Drive Expansion of Leukemia Cells-of-Origin and Established Tumor Clones

Blood (2018) 132 (Supplement 1): 1322.

https://doi.org/10.1182/blood-2018-99-120120

Published: 2018

Journal Articles

Improved Clinical Assessment of Myeloid Malignancies By Transcriptome Profiling

Rod Docking, MSc, Aly Karsan, MD

Blood (2017) 130 (Supplement 1): 3938.

https://doi.org/10.1182/blood.V130.Suppl_1.3938.3938

Published: 2017

Journal Articles

Single Cell-Resolution Analysis of HSC Dysfunction in Mir-146a knockout Mice

Jennifer Grants, PhD, Joanna Wegrzyn, PhD, David Knapp, PhD, Tony Hui, Kieran O'Neill, PhD, Jeremy Parker, PhD, Deborah Deng, Mark Boldin, PhD, Martin Hirst, PhD, Connie J. Eaves, PhD, Aly Karsan, MD

Blood (2017) 130 (Supplement 1): 714.

https://doi.org/10.1182/blood.V130.Suppl_1.714.714

Published: 2017

NARROW

Is Allogeneic Hematopoietic Stem Cell Transplant (HCT) in First Remission Beneficial to Acute Myeloid Leukemia (AML) Patients with Isocitrate Dehydrogenase(IDH) Mutations?

Acute Myeloid Leukemia (AML) Patients with Myelodysplasia (MDS) Related-Gene Mutations in First Complete Remission (CR1) Found to Have Benefit from Allogeneic Hematopoietic Stem Cell Transplant (HCT)

A noncanonical enzymatic function of PIWIL4 maintains genomic integrity and leukemic growth in AML

Loss of FBXO11 Function Establishes a Stem Cell Program in Acute Myeloid Leukemia through Dysregulation of the Mitochondrial Protease LONP1

Relapse Timing Is Associated with Distinct Evolutionary Dynamics and Response to Salvage Therapy in DLBCL

Meis1 Establishes the Pre-Hemogenic Endothelial State Prior to Runx1 Expression

Chromatin Architecture Protein CTCF Plays a Role in Determining 5-Azacytidine Response of Leukemic Cells By Potentially Regulating Hoxb Genes

Inflammation and myeloid malignancy: quenching the flame

Elucidating the Importance and Regulation of Key Enhancers for Human MEIS1 Expression

Elucidating the Mechanisms of Leukemogenesis Driven By FBXO11 Depletion

Single-Cell Profiling Reveals Clinically Relevant Evolutionary Trajectories and Alternate Biologies in Human Follicular Lymphoma

TIRAP Drives Marrow Failure through an Ifnγ-Hmgb1 Axis That Disrupts the Endothelial Niche

SF3B1 -mutant MDS as a distinct disease subtype: a proposal from the International Working Group for the Prognosis of MDS

Altered microRNA expression links IL6 and TNF-induced inflammaging with myeloid malignancy in humans and mice

Resistance to Lenalidomide in Del(5q) MDS Is Mediated By Inhibition of Drug-Induced Megakaryocytic Differentiation

Outcomes of Patients with Low Variant Allele Fraction JAK2V617F : A 5-Year Retrospective Analysis

Synthetic De Novo Modeling of Human T-Cell Acute Lymphoblastic Leukemia Reveals HOXB Genes Drive Expansion of Leukemia Cells-of-Origin and Established Tumor Clones

Improved Clinical Assessment of Myeloid Malignancies By Transcriptome Profiling

Single Cell-Resolution Analysis of HSC Dysfunction in Mir-146a knockout Mice

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American Society of Hematology

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ASH Publications

American Society of Hematology

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