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Manuela Cruz
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Journal Articles

Motive and opportunity: MYC rearrangements in high-grade B-cell lymphoma with MYC and BCL2 rearrangements (an LLMPP study)

Laura K. Hilton, Brett Collinge, Susana Ben-Neriah, Waleed Alduaij, Haya Shaalan, Andrew P. Weng, Manuela Cruz, Graham W. Slack, Pedro Farinha, Tomoko Miyata-Takata, Merrill Boyle, Barbara Meissner, James R. Cook, Sarah L. Ondrejka, German Ott, Andreas Rosenwald, Elias Campo, Catalina Amador, Timothy C. Greiner, Philipp W. Raess, Joo Y. Song, Giorgio Inghirami, Elaine S. Jaffe, Dennis D. Weisenburger, Wing C. Chan, Klaus Beiske, Kai Fu, Jan Delabie, Stefania Pittaluga, Javeed Iqbal, George Wright, Laurie H. Sehn, Kerry J. Savage, Andrew J. Mungall, Andrew L. Feldman, Louis M. Staudt, Christian Steidl, Lisa M. Rimsza, Ryan D. Morin, David W. Scott
Journal: Blood
Blood (2024) 144 (5): 525–540.
https://doi.org/10.1182/blood.2024024251
Published: 2024
Includes: Supplemental data
Journal Articles

Large-Scale Genomic Analysis of Mutational Hotspots in Burkitt Lymphoma and Diffuse Large B-Cell Lymphoma

Manuela Cruz, Kostiantyn Dreval, Prasath Pararajalingam, Laura Hilton, Jasper Wong, Christopher Rushton, Ryan Morin
Journal: Blood
Blood (2023) 142 (Supplement 1): 2992.
https://doi.org/10.1182/blood-2023-185914
Published: 2023
Journal Articles

Genetic subdivisions of follicular lymphoma defined by distinct coding and noncoding mutation patterns

Kostiantyn Dreval, Laura K. Hilton, Manuela Cruz, Haya Shaalan, Susana Ben-Neriah, Merrill Boyle, Brett Collinge, Krysta M. Coyle, Gerben Duns, Pedro Farinha, Bruno M. Grande, Barbara Meissner, Prasath Pararajalingam, Christopher K. Rushton, Graham W. Slack, Jasper Wong, Andrew J. Mungall, Marco A. Marra, Joseph M. Connors, Christian Steidl, David W. Scott, Ryan D. Morin
Journal: Blood
Blood (2023) 142 (6): 561–573.
https://doi.org/10.1182/blood.2022018719
Published: 2023
Includes: Supplemental data
Journal Articles

Genetic subgroups inform on pathobiology in adult and pediatric Burkitt lymphoma

Nicole Thomas, Kostiantyn Dreval, Daniela S. Gerhard, Laura K. Hilton, Jeremy S. Abramson, Richard F. Ambinder, Stefan Barta, Nancy L. Bartlett, Jeffrey Bethony, Kishor Bhatia, Jay Bowen, Anthony C. Bryan, Ethel Cesarman, Corey Casper, Amy Chadburn, Manuela Cruz, Dirk P. Dittmer, Maureen A. Dyer, Pedro Farinha, Julie M. Gastier-Foster, Alina S. Gerrie, Bruno M. Grande, Timothy Greiner, Nicholas B. Griner, Thomas G. Gross, Nancy L. Harris, John D. Irvin, Elaine S. Jaffe, David Henry, Rebecca Huppi, Fabio E. Leal, Michael S. Lee, Jean Paul Martin, Marie-Reine Martin, Sam M. Mbulaiteye, Ronald Mitsuyasu, Vivian Morris, Charles G. Mullighan, Andrew J. Mungall, Karen Mungall, Innocent Mutyaba, Mostafa Nokta, Constance Namirembe, Ariela Noy, Martin D. Ogwang, Abraham Omoding, Jackson Orem, German Ott, Hilary Petrello, Stefania Pittaluga, James D. Phelan, Juan Carlos Ramos, Lee Ratner, Steven J. Reynolds, Paul G. Rubinstein, Gerhard Sissolak, Graham Slack, Shaghayegh Soudi, Steven H. Swerdlow, Alexandra Traverse-Glehen, Wyndham H. Wilson, Jasper Wong, Robert Yarchoan, Jean C. ZenKlusen, Marco A. Marra, Louis M. Staudt, David W. Scott, Ryan D. Morin
Journal: Blood
Blood (2023) 141 (8): 904–916.
https://doi.org/10.1182/blood.2022016534
Published: 2023
Includes: Supplemental data
Journal Articles

Relapse Timing Is Associated with Distinct Evolutionary Dynamics and Response to Salvage Therapy in DLBCL

Laura K Hilton, Henry S. Ngu, Brett Collinge, Kostiantyn Dreval, Susana Ben-Neriah, Christopher K Rushton, Jasper Wong, Manuela Cruz, Andrew Roth, Merrill Boyle, Barbara Meissner, Graham W. Slack, Pedro Farinha, Jeffrey W. Craig, Alina S. Gerrie, Ciara L. Freeman, Diego Villa, Kerry J. Savage, Laurie H. Sehn, Marco A. Marra, Aly Karsan, Christian Steidl, Ryan D. Morin, David W. Scott
Journal: Blood
Blood (2022) 140 (Supplement 1): 1310–1312.
https://doi.org/10.1182/blood-2022-160187
Published: 2022
Journal Articles

Towards a Unified Genetic Classification System for Diffuse Large B-Cell Lymphoma (DLBCL)

Kostiantyn Dreval, Laura K Hilton, Krysta M. Coyle, Jasper Wong, Merrill Boyle, Brett Collinge, Manuela Cruz, Barbara Meissner, Christopher K Rushton, Marco A. Marra, David W. Scott, Christian Steidl, Ryan D. Morin
Journal: Blood
Blood (2022) 140 (Supplement 1): 3495–3497.
https://doi.org/10.1182/blood-2022-167043
Published: 2022
Journal Articles

Recurrent Copy Number Alterations Contribute to a Unique Genetic Landscape in Relapsed-Refractory DLBCL

Christopher K Rushton, Ryan N Rys, Elizabeth Chavez, Laura K Hilton, Miguel Alcaide, Kostiantyn Dreval, Matthew Cheung, Manuela Cruz, Krysta M. Coyle, Barbara Meissner, Susana Ben-Neriah, Neil R. Michaud, Scott Daigle, Jordan Davidson, Jasper Wong, Annette E. Hay, Michael D. Jain, Lois E. Shepherd, Marco A. Marra, John Kuruvilla, Michael Crump, Koren Kathleen Mann, Sarit Assouline, Christian Steidl, David W. Scott, Nathalie A. Johnson, Ryan D. Morin
Journal: Blood
Blood (2022) 140 (Supplement 1): 9259–9260.
https://doi.org/10.1182/blood-2022-169623
Published: 2022
Journal Articles

Constrained FL: A Genetically Distinct Subgroup of Follicular Lymphoma with Low Rates of Somatic Hypermutation and a Reduced Propensity for Histologic Transformation

Laura K Hilton, Kostiantyn Dreval, Shaghayegh Soudi, Susana Ben-Neriah, Manuela Cruz, Brett Collinge, Krysta M. Coyle, Bruno M. Grande, Gerben Duns, Christopher K Rushton, Merrill Boyle, Barbara Meissner, Pedro Farinha, Graham W Slack, Andrew J. Mungall, Marco A. Marra, Joseph M. Connors, Christian Steidl, David W. Scott, Ryan D Morin
Journal: Blood
Blood (2021) 138 (Supplement 1): 807.
https://doi.org/10.1182/blood-2021-153445
Published: 2021
Journal Articles

An Open-Source Toolkit That Powers the Genome-Wide Analysis of Mature B-Cell Lymphomas (GAMBL) Project

Kostiantyn Dreval, Bruno M. Grande, Helena Winata, Jasper Wong, Lakshay Sethi, Christopher K. Rushton, Prasath Pararajalingam, Sarah E. Arthur, Lauren C. Chong, Brett Collinge, Krysta M. Coyle, Manuela Cruz, Stacy Hung, Shaghayegh Soudi, Nicole Thomas, Christian Steidl, David W. Scott, Ryan D Morin, Laura K Hilton
Journal: Blood
Blood (2021) 138 (Supplement 1): 1873.
https://doi.org/10.1182/blood-2021-147548
Published: 2021
Journal Articles

Novel Genetic Subgroups Inform on Shared Pathobiology within Adult and Pediatric Burkitt Lymphoma

Nicole Thomas, Kostiantyn Dreval, Daniela S. Gerhard, Laura K Hilton, Jeremy S. Abramson, Nancy L. Bartlett, Jeffrey Bethony, Jay Bowen, Anthony Bryan, Corey Casper, Manuela Cruz, Maureen Dyer, Julie M Gastier-Foster, Alina S. Gerrie, Bruno M. Grande, Timothy C. Greiner, Nicholas B. Griner, Thomas G. Gross, Nancy Lee Harris, John D. Irvin, Elaine S. Jaffe, Fabio Leal, Jean Paul Martin, Marie-Reine Martin, Sam M. Mbulaiteye, Charles G. Mullighan, Andrew J. Mungall, Karen Mungall, Constance Namirembe, Ariela Noy, Martin Ogwang, Jackson Orem, German Ott, Hilary Petrello, Steven Reynolds, Shaghayegh Soudi, Steven H. Swerdlow, Alexandra Traverse-Glehen, Wyndham H. Wilson, Jasper Wong, Marco A. Marra, Louis M. Staudt, David W. Scott, Ryan D Morin
Journal: Blood
Blood (2021) 138 (Supplement 1): 806.
https://doi.org/10.1182/blood-2021-147916
Published: 2021