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Kostiantyn Dreval
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Journal Articles

Large-Scale Genomic Analysis of Mutational Hotspots in Burkitt Lymphoma and Diffuse Large B-Cell Lymphoma

Manuela Cruz, Kostiantyn Dreval, Prasath Pararajalingam, Laura Hilton, Jasper Wong, Christopher Rushton, Ryan Morin
Journal: Blood
Blood (2023) 142 (Supplement 1): 2992.
https://doi.org/10.1182/blood-2023-185914
Published: 2023
Journal Articles

Hnrnpu mutations Are Haploinsufficient and Alter the Transcriptome of MYC-Driven Lymphomas

Qurat Ul Ain Qureshi, Krysta Mila Coyle, Nicole Thomas, Brett Collinge, Kostiantyn Dreval, Laura Hilton, Jasper Wong, David W. Scott, Timothy Audas, Ryan Morin
Journal: Blood
Blood (2023) 142 (Supplement 1): 1399.
https://doi.org/10.1182/blood-2023-190409
Published: 2023
Journal Articles

Concerning data inconsistencies in Burkitt lymphoma genome study

Christopher K. Rushton, Kostiantyn Dreval, Ryan D. Morin
Journal: Blood
Blood (2023) 142 (10): 933–936.
https://doi.org/10.1182/blood.2022016505
Published: 2023
Includes: Supplemental data
Journal Articles

Genetic subdivisions of follicular lymphoma defined by distinct coding and noncoding mutation patterns

Kostiantyn Dreval, Laura K. Hilton, Manuela Cruz, Haya Shaalan, Susana Ben-Neriah, Merrill Boyle, Brett Collinge, Krysta M. Coyle, Gerben Duns, Pedro Farinha, Bruno M. Grande, Barbara Meissner, Prasath Pararajalingam, Christopher K. Rushton, Graham W. Slack, Jasper Wong, Andrew J. Mungall, Marco A. Marra, Joseph M. Connors, Christian Steidl, David W. Scott, Ryan D. Morin
Journal: Blood
Blood (2023) 142 (6): 561–573.
https://doi.org/10.1182/blood.2022018719
Published: 2023
Includes: Supplemental data
Journal Articles

Genetic subgroups inform on pathobiology in adult and pediatric Burkitt lymphoma

Nicole Thomas, Kostiantyn Dreval, Daniela S. Gerhard, Laura K. Hilton, Jeremy S. Abramson, Richard F. Ambinder, Stefan Barta, Nancy L. Bartlett, Jeffrey Bethony, Kishor Bhatia, Jay Bowen, Anthony C. Bryan, Ethel Cesarman, Corey Casper, Amy Chadburn, Manuela Cruz, Dirk P. Dittmer, Maureen A. Dyer, Pedro Farinha, Julie M. Gastier-Foster, Alina S. Gerrie, Bruno M. Grande, Timothy Greiner, Nicholas B. Griner, Thomas G. Gross, Nancy L. Harris, John D. Irvin, Elaine S. Jaffe, David Henry, Rebecca Huppi, Fabio E. Leal, Michael S. Lee, Jean Paul Martin, Marie-Reine Martin, Sam M. Mbulaiteye, Ronald Mitsuyasu, Vivian Morris, Charles G. Mullighan, Andrew J. Mungall, Karen Mungall, Innocent Mutyaba, Mostafa Nokta, Constance Namirembe, Ariela Noy, Martin D. Ogwang, Abraham Omoding, Jackson Orem, German Ott, Hilary Petrello, Stefania Pittaluga, James D. Phelan, Juan Carlos Ramos, Lee Ratner, Steven J. Reynolds, Paul G. Rubinstein, Gerhard Sissolak, Graham Slack, Shaghayegh Soudi, Steven H. Swerdlow, Alexandra Traverse-Glehen, Wyndham H. Wilson, Jasper Wong, Robert Yarchoan, Jean C. ZenKlusen, Marco A. Marra, Louis M. Staudt, David W. Scott, Ryan D. Morin
Journal: Blood
Blood (2023) 141 (8): 904–916.
https://doi.org/10.1182/blood.2022016534
Published: 2023
Includes: Supplemental data
Journal Articles

Minimal information for reporting a genomics experiment

Kostiantyn Dreval, Paul C. Boutros, Ryan D. Morin
Journal: Blood
Blood (2022) 140 (24): 2549–2555.
https://doi.org/10.1182/blood.2022016095
Published: 2022
Includes: Supplemental data
Journal Articles

Mutations of the RNA Binding Protein hnRNP U Modulate MYC Expression in MYC-Driven Lymphomas

Qurat Ul Ain Qureshi, Krysta M. Coyle, Nicole Thomas, Brett Collinge, Kostiantyn Dreval, David W. Scott, Timothy E Audas, Ryan D. Morin
Journal: Blood
Blood (2022) 140 (Supplement 1): 2036–2037.
https://doi.org/10.1182/blood-2022-167934
Published: 2022
Journal Articles

Recurrent Copy Number Alterations Contribute to a Unique Genetic Landscape in Relapsed-Refractory DLBCL

Christopher K Rushton, Ryan N Rys, Elizabeth Chavez, Laura K Hilton, Miguel Alcaide, Kostiantyn Dreval, Matthew Cheung, Manuela Cruz, Krysta M. Coyle, Barbara Meissner, Susana Ben-Neriah, Neil R. Michaud, Scott Daigle, Jordan Davidson, Jasper Wong, Annette E. Hay, Michael D. Jain, Lois E. Shepherd, Marco A. Marra, John Kuruvilla, Michael Crump, Koren Kathleen Mann, Sarit Assouline, Christian Steidl, David W. Scott, Nathalie A. Johnson, Ryan D. Morin
Journal: Blood
Blood (2022) 140 (Supplement 1): 9259–9260.
https://doi.org/10.1182/blood-2022-169623
Published: 2022
Journal Articles

Relapse Timing Is Associated with Distinct Evolutionary Dynamics and Response to Salvage Therapy in DLBCL

Laura K Hilton, Henry S. Ngu, Brett Collinge, Kostiantyn Dreval, Susana Ben-Neriah, Christopher K Rushton, Jasper Wong, Manuela Cruz, Andrew Roth, Merrill Boyle, Barbara Meissner, Graham W. Slack, Pedro Farinha, Jeffrey W. Craig, Alina S. Gerrie, Ciara L. Freeman, Diego Villa, Kerry J. Savage, Laurie H. Sehn, Marco A. Marra, Aly Karsan, Christian Steidl, Ryan D. Morin, David W. Scott
Journal: Blood
Blood (2022) 140 (Supplement 1): 1310–1312.
https://doi.org/10.1182/blood-2022-160187
Published: 2022
Journal Articles

Exploring Splicing Factor Aberrations As a Therapeutic Target in Mature B-Cell Malignancies

Krysta M. Coyle, Qurat Ul Ain Qureshi, Balwinder Ruprai, Tejdeep Kang, Laura K Hilton, Kostiantyn Dreval, Prasath Pararajalingam, Christopher K Rushton, Nicole Thomas, Timothy E Audas, Ryan D. Morin
Journal: Blood
Blood (2022) 140 (Supplement 1): 1747–1748.
https://doi.org/10.1182/blood-2022-160377
Published: 2022
Journal Articles

DNA Methylation-Based Burkitt Lymphoma Epitypes Have Distinct Molecular and Clinical Features

Nicole Thomas, Kostiantyn Dreval, Daniela S. Gerhard, Laura K Hilton, Jeremy S. Abramson, Nancy L. Bartlett, Jeffrey Bethony, Jay Bowen, Anthony Bryan, Corey Casper, Maureen Dyer, Manel Esteller, Carlos Garcia-Prieto, Julie M Gastier-Foster, Alina S. Gerrie, Bruno M. Grande, Timothy C. Greiner, Nicholas B. Griner, Thomas G. Gross, Nancy Lee Harris, John D. Irvin, Elaine S. Jaffe, Fabio Leal, Jean Paul Martin, Marie-Reine Martin, Sam M. Mbulaiteye, Charles G. Mullighan, Andrew J. Mungall, Karen Mungall, Constance Namirembe, Ariela Noy, Martin D Ogwang, Jackson Orem, German Ott, Hilary Petrello, Steven J Reynolds, Steven H. Swerdlow, Alexandra Traverse-Glehen, Wyndham H. Wilson, Marco A. Marra, Louis M. Staudt, David W. Scott, Ryan D. Morin
Journal: Blood
Blood (2022) 140 (Supplement 1): 1734–1736.
https://doi.org/10.1182/blood-2022-163728
Published: 2022
Journal Articles

Towards a Unified Genetic Classification System for Diffuse Large B-Cell Lymphoma (DLBCL)

Kostiantyn Dreval, Laura K Hilton, Krysta M. Coyle, Jasper Wong, Merrill Boyle, Brett Collinge, Manuela Cruz, Barbara Meissner, Christopher K Rushton, Marco A. Marra, David W. Scott, Christian Steidl, Ryan D. Morin
Journal: Blood
Blood (2022) 140 (Supplement 1): 3495–3497.
https://doi.org/10.1182/blood-2022-167043
Published: 2022
Journal Articles

Complex Structural Variation Associated with Enhancer Hijacking and Loss of Tumor Suppressors in Mantle Cell Lymphoma

Prasath Pararajalingam, Laura K Hilton, Krysta M. Coyle, Kostiantyn Dreval, Barbara Meissner, Ari Melnick, Marco A. Marra, David W. Scott, Ryan D Morin
Journal: Blood
Blood (2021) 138 (Supplement 1): 675.
https://doi.org/10.1182/blood-2021-153162
Published: 2021
Journal Articles

Shared and Distinct Genetic Features in Human and Canine B-Cell Lymphomas

Tiana Hillman, Matthew Cheung, Bruno M. Grande, Kevin R Bushell, Sarah E. Arthur, Miguel Alcaide, Nicole Thomas, Kostiantyn Dreval, Jovanveer Shoker, Krishanna Campbell, Stephanie Wong, Ryan D Morin, Krysta M. Coyle
Journal: Blood
Blood (2021) 138 (Supplement 1): 3509.
https://doi.org/10.1182/blood-2021-153928
Published: 2021
Journal Articles

An Open-Source Toolkit That Powers the Genome-Wide Analysis of Mature B-Cell Lymphomas (GAMBL) Project

Kostiantyn Dreval, Bruno M. Grande, Helena Winata, Jasper Wong, Lakshay Sethi, Christopher K. Rushton, Prasath Pararajalingam, Sarah E. Arthur, Lauren C. Chong, Brett Collinge, Krysta M. Coyle, Manuela Cruz, Stacy Hung, Shaghayegh Soudi, Nicole Thomas, Christian Steidl, David W. Scott, Ryan D Morin, Laura K Hilton
Journal: Blood
Blood (2021) 138 (Supplement 1): 1873.
https://doi.org/10.1182/blood-2021-147548
Published: 2021
Journal Articles

Novel Genetic Subgroups Inform on Shared Pathobiology within Adult and Pediatric Burkitt Lymphoma

Nicole Thomas, Kostiantyn Dreval, Daniela S. Gerhard, Laura K Hilton, Jeremy S. Abramson, Nancy L. Bartlett, Jeffrey Bethony, Jay Bowen, Anthony Bryan, Corey Casper, Manuela Cruz, Maureen Dyer, Julie M Gastier-Foster, Alina S. Gerrie, Bruno M. Grande, Timothy C. Greiner, Nicholas B. Griner, Thomas G. Gross, Nancy Lee Harris, John D. Irvin, Elaine S. Jaffe, Fabio Leal, Jean Paul Martin, Marie-Reine Martin, Sam M. Mbulaiteye, Charles G. Mullighan, Andrew J. Mungall, Karen Mungall, Constance Namirembe, Ariela Noy, Martin Ogwang, Jackson Orem, German Ott, Hilary Petrello, Steven Reynolds, Shaghayegh Soudi, Steven H. Swerdlow, Alexandra Traverse-Glehen, Wyndham H. Wilson, Jasper Wong, Marco A. Marra, Louis M. Staudt, David W. Scott, Ryan D Morin
Journal: Blood
Blood (2021) 138 (Supplement 1): 806.
https://doi.org/10.1182/blood-2021-147916
Published: 2021
Journal Articles

Constrained FL: A Genetically Distinct Subgroup of Follicular Lymphoma with Low Rates of Somatic Hypermutation and a Reduced Propensity for Histologic Transformation

Laura K Hilton, Kostiantyn Dreval, Shaghayegh Soudi, Susana Ben-Neriah, Manuela Cruz, Brett Collinge, Krysta M. Coyle, Bruno M. Grande, Gerben Duns, Christopher K Rushton, Merrill Boyle, Barbara Meissner, Pedro Farinha, Graham W Slack, Andrew J. Mungall, Marco A. Marra, Joseph M. Connors, Christian Steidl, David W. Scott, Ryan D Morin
Journal: Blood
Blood (2021) 138 (Supplement 1): 807.
https://doi.org/10.1182/blood-2021-153445
Published: 2021