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Journal Articles

Narazaciclib, a Differentiated CDK4/6 Antagonist, Prolongs Cell Cycle Arrest and Metabolomic Reprogramming, Enabling Restoration of Ibrutinib Sensitivity in Btki-Resistant Mantle Cell Lymphoma

Nuria Profitos-Peleja, Marcelo Lima Ribeiro, Jeronimo Parra, Miranda Fernandez-Serrano, Pau Marin-Escudero, Joan Josep Bech, Carolina De La Torre, Adar Makovski Silverstein, Steve Cosenza, Steven M. Fruchtman, Manel Esteller, Gael Roue

Blood (2023) 142 (Supplement 1): 4181.

https://doi.org/10.1182/blood-2023-189838

Published: 2023

Journal Articles

Deciphering Transcriptomic and (Epi)Genetic Signatures of Central Nervous System Infiltration in Patients Diagnosed with Diffuse Large B-Cell Lymphoma

Carlota Pages-Geli, Sabela Bobillo, Pau Abrisqueta, Josep Castellvi, Laura Palomo, Damiana Alvarez, Manel Esteller, Francesc Bosch, Marta Crespo

Blood (2023) 142 (Supplement 1): 1618.

https://doi.org/10.1182/blood-2023-174653

Published: 2023

Journal Articles

Multiomic Characterization of Myelodysplastic Neoplasms (MDS) with Micromegakaryocytes Highlights the Role of EZH2-RUNX1 deregulation in Disease Physiopathology and Response to Targeted Therapies

Blood (2023) 142 (Supplement 1): 4116.

https://doi.org/10.1182/blood-2023-188848

Published: 2023

Journal Articles

CD155 on Multiple Myeloma Cells Is Epigenetically Regulated, Reduce Patients Survival and Compromises the Action of Novel Immunotherapies

Laura Martinez-Verbo, Lorea Villanueva, Pere Llinàs-Arias, Carlos Antonio García-Prieto, David Piñeyro, Aina Oliver-Caldes, Almudena García-Ortiz, Antonio Valeri, Carlos Fernández de Larrea, Joaquin Martinez-Lopez, Gerardo Ferrer, Manel Esteller

Blood (2023) 142 (Supplement 1): 6567.

https://doi.org/10.1182/blood-2023-179313

Published: 2023

Journal Articles

Bone Marrow WT1 mRNA Upregulation in Acute Myeloid Leukemia (AML) in Complete Molecular Remission (mCR): Understanding the Limitations and Advantages of WT1 As a Measurable Residual Disease (MRD) Target

Albert Esquirol, Yolanda Guillén, Elena Bussaglia, Vanesa Criado, Maite Carricondo, Pamela Acha, Manel Esteller, Jorge Sierra, Francesc Solé, Anna Bigas, Josep F Nomdedeu

Blood (2022) 140 (Supplement 1): 11786–11787.

https://doi.org/10.1182/blood-2022-166117

Published: 2022

Journal Articles

DNA Methylation-Based Burkitt Lymphoma Epitypes Have Distinct Molecular and Clinical Features

Blood (2022) 140 (Supplement 1): 1734–1736.

https://doi.org/10.1182/blood-2022-163728

Published: 2022

Journal Articles

Epigenetic loss of m 1 A RNA demethylase ALKBH3 in Hodgkin lymphoma targets collagen, conferring poor clinical outcome

Blood (2021) 137 (7): 994–999.

https://doi.org/10.1182/blood.2020005823

Published: 2021

Includes: Supplemental data

Journal Articles

Induced Transdifferentiation of Leukemia B-Cells to Macrophages Involves Reconfiguration of the DNA Methylome

Alberto Bueno-Costa, David Piñeyro, Marta Soler, Biola Maria Javierre, José Angel Martínez-Climent, Manel Esteller, MD PhD

Blood (2018) 132 (Supplement 1): 5115.

https://doi.org/10.1182/blood-2018-99-111580

Published: 2018

Journal Articles

Efficacy of a New Small-Molecule Inhibitor of Histone Deacetylase 6 (HDAC6) in Preclinical Models of B-Cell Lymphoma and Acute Myeloid Leukemia

Blood (2018) 132 (Supplement 1): 5383.

https://doi.org/10.1182/blood-2018-99-111578

Published: 2018

Journal Articles

Epigenomic Analysis of Acute Myeloid Leukemia Identifies Specific Patterns and Markes with Clinical and Biological Relevance.

Sara Alvarez, MD, PhD, Javier Suela, PhD, Ana Valencia, MD, Agustin Fernandez, PhD, Mark Wunderlich, MS, Xabier Agirre, PhD, Felipe Prosper, MD, Jose Ignacio Martin-Subero, PhD, Alba Maiques, MSc, Francesco Acquadro, MSc, Sandra Rodriguez-Perales, PhD, Maria J. Calasanz, PhD, Jose Roman-Gomez, MD, Reiner Siebert, MD, PhD, James C. Mulloy, PhD, José Cervera, MD, PhD, Miguel A. Sanz, MD, PhD, Manel Esteller, MD, PhD, Juan C Cigudosa, PhD

Blood (2009) 114 (22): 2394.

https://doi.org/10.1182/blood.V114.22.2394.2394

Published: 2009

Journal Articles

New insights into the biology and origin of mature aggressive B-cell lymphomas by combined epigenomic, genomic, and transcriptional profiling

Blood (2009) 113 (11): 2488–2497.

https://doi.org/10.1182/blood-2008-04-152900

Published: 2009

Includes: Supplemental data

Journal Articles

The novel DNA methylation inhibitor zebularine is effective against the development of murine T-cell lymphoma

Michel Herranz, Juan Martín-Caballero, Mario F. Fraga, Jesús Ruiz-Cabello, Juana Maria Flores, Manuel Desco, Victor Marquez, Manel Esteller

Blood (2006) 107 (3): 1174–1177.

https://doi.org/10.1182/blood-2005-05-2033

Published: 2006

Includes: Supplemental data

Journal Articles

Characterization of 8p21.3 chromosomal deletions in B-cell lymphoma: TRAIL-R1 and TRAIL-R2 as candidate dosage-dependent tumor suppressor genes

Fanny Rubio-Moscardo, David Blesa, Cinta Mestre, Reiner Siebert, Theo Balasas, Adalberto Benito, Andreas Rosenwald, Joan Climent, Jose I. Martinez, Markus Schilhabel, E. Lorraine Karran, Stefan Gesk, Manel Esteller, Ronald deLeeuw, Louis M. Staudt, Jose Luis Fernandez-Luna, Daniel Pinkel, Martin J. S. Dyer, Jose A. Martinez-Climent

Blood (2005) 106 (9): 3214–3222.

https://doi.org/10.1182/blood-2005-05-2013

Published: 2005

Includes: Supplemental data

Journal Articles

The Histone Deacetylase 9 Gene Is Regulated by Multiple Promoters and Expresses Lymphoid-Specific Isoforms.

Kevin Petrie, BSc, Louise Howell, MSc, Estella Matutes, MD, Samuel Waxman, MD, Miguel Angel Piris, MD, Manel Esteller, MD, Arthur Zelent, PhD

Blood (2004) 104 (11): 1120.

https://doi.org/10.1182/blood.V104.11.1120.1120

Published: 2004

Journal Articles

SOCS-1, a negative regulator of cytokine signaling, is frequently silenced by methylation in multiple myeloma

Oliver Galm, Hirohide Yoshikawa, Manel Esteller, Rainhardt Osieka, James G. Herman

Blood (2003) 101 (7): 2784–2788.

https://doi.org/10.1182/blood-2002-06-1735

Published: 2003

Journal Articles

CHK2-decreased protein expression and infrequent genetic alterations mainly occur in aggressive types of non-Hodgkin lymphomas

Frederic Tort, Silvia Hernàndez, Silvia Beà, Antonio Martı́nez, Manel Esteller, James G. Herman, Xavier Puig, Emma Camacho, Montse Sánchez, Iracema Nayach, Armando Lopez-Guillermo, Pedro L. Fernández, Dolors Colomer, Luis Hernàndez, Elias Campo

Blood (2002) 100 (13): 4602–4608.

https://doi.org/10.1182/blood-2002-04-1078

Published: 2002

NARROW

Narazaciclib, a Differentiated CDK4/6 Antagonist, Prolongs Cell Cycle Arrest and Metabolomic Reprogramming, Enabling Restoration of Ibrutinib Sensitivity in Btki-Resistant Mantle Cell Lymphoma

Deciphering Transcriptomic and (Epi)Genetic Signatures of Central Nervous System Infiltration in Patients Diagnosed with Diffuse Large B-Cell Lymphoma

Multiomic Characterization of Myelodysplastic Neoplasms (MDS) with Micromegakaryocytes Highlights the Role of EZH2-RUNX1 deregulation in Disease Physiopathology and Response to Targeted Therapies

CD155 on Multiple Myeloma Cells Is Epigenetically Regulated, Reduce Patients Survival and Compromises the Action of Novel Immunotherapies

Bone Marrow WT1 mRNA Upregulation in Acute Myeloid Leukemia (AML) in Complete Molecular Remission (mCR): Understanding the Limitations and Advantages of WT1 As a Measurable Residual Disease (MRD) Target

DNA Methylation-Based Burkitt Lymphoma Epitypes Have Distinct Molecular and Clinical Features

Epigenetic loss of m 1 A RNA demethylase ALKBH3 in Hodgkin lymphoma targets collagen, conferring poor clinical outcome

Induced Transdifferentiation of Leukemia B-Cells to Macrophages Involves Reconfiguration of the DNA Methylome

Efficacy of a New Small-Molecule Inhibitor of Histone Deacetylase 6 (HDAC6) in Preclinical Models of B-Cell Lymphoma and Acute Myeloid Leukemia

Epigenomic Analysis of Acute Myeloid Leukemia Identifies Specific Patterns and Markes with Clinical and Biological Relevance.

New insights into the biology and origin of mature aggressive B-cell lymphomas by combined epigenomic, genomic, and transcriptional profiling

The novel DNA methylation inhibitor zebularine is effective against the development of murine T-cell lymphoma

Characterization of 8p21.3 chromosomal deletions in B-cell lymphoma: TRAIL-R1 and TRAIL-R2 as candidate dosage-dependent tumor suppressor genes

The Histone Deacetylase 9 Gene Is Regulated by Multiple Promoters and Expresses Lymphoid-Specific Isoforms.

SOCS-1, a negative regulator of cytokine signaling, is frequently silenced by methylation in multiple myeloma

CHK2-decreased protein expression and infrequent genetic alterations mainly occur in aggressive types of non-Hodgkin lymphomas

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American Society of Hematology

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ASH Publications

American Society of Hematology

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