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Mario F. Fraga
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Journal Articles

NG2 is a target gene of MLL-AF4 and underlies glucocorticoid resistance in MLLr B-ALL by regulating NR3C1 expression

Belén Lopez-Millan, Alba Rubio-Gayarre, Meritxell Vinyoles, Juan L. Trincado, Mario F. Fraga, Narcís Fernandez-Fuentes, Mercedes Guerrero-Murillo, Alba Martinez, Talia Velasco-Hernandez, Aïda Falgàs, Carla Panisello, Gemma Valcarcel, José Luis Sardina, Paula López-Martí, Biola M. Javierre, Beatriz Del Valle-Pérez, Antonio García de Herreros, Franco Locatelli, Rob Pieters, Michela Bardini, Giovanni Cazzaniga, Juan Carlos Rodríguez-Manzaneque, Thomas Hanewald, Rolf Marschalek, Thomas A. Milne, Ronald W. Stam, Juan Ramón Tejedor, Pablo Menendez, Clara Bueno
Journal: Blood
Blood (2024) 144 (19): 2002–2017.
https://doi.org/10.1182/blood.2023022050
Published: 2024
Includes: Supplemental data
Journal Articles

A human genome editing–based MLL :: AF4 ALL model recapitulates key cellular and molecular leukemogenic features

Clara Bueno, Raul Torres-Ruiz, Talia Velasco-Hernandez, Oscar Molina, Paolo Petazzi, Alba Martinez, Virginia Rodriguez, Meritxell Vinyoles, Sandra Cantilena, Owen Williams, Nerea Vega-Garcia, Sandra Rodriguez-Perales, Jose C. Segovia, Oscar Quintana-Bustamante, Anindita Roy, Claus Meyer, Rolf Marschalek, Alastair L. Smith, Thomas A. Milne, Mario F. Fraga, Juan Ramón Tejedor, Pablo Menéndez
Journal: Blood
Blood (2023) 142 (20): 1752–1756.
https://doi.org/10.1182/blood.2023020858
Published: 2023
Includes: Supplemental data
Journal Articles

Epigenetic loss of m 1 A RNA demethylase ALKBH3 in Hodgkin lymphoma targets collagen, conferring poor clinical outcome

Rosaura Esteve-Puig, Fina Climent, David Piñeyro, Eva Domingo-Domènech, Veronica Davalos, Maite Encuentra, Anna Rea, Nadia Espejo-Herrera, Marta Soler, Miguel Lopez, Vanessa Ortiz-Barahona, Gustavo Tapia, José-Tomás Navarro, Joan Cid, Lourdes Farré, Alberto Villanueva, Isolda Casanova, Ramon Mangues, Pablo Santamarina-Ojeda, Agustín F. Fernández, Mario F. Fraga, Miguel Angel Piris, Nitzan Kol, Chen Avrahami, Sharon Moshitch-Moshkovitz, Gideon Rechavi, Anna Sureda, Manel Esteller
Journal: Blood
Blood (2021) 137 (7): 994–999.
https://doi.org/10.1182/blood.2020005823
Published: 2021
Includes: Supplemental data
Journal Articles

Natural history and cell of origin of TC F3 - ZN F384 and PTPN11 mutations in monozygotic twins with concordant BCP-ALL

Clara Bueno, J. Ramón Tejedor, Rachael Bashford-Rogers, Laura González-Silva, Rafael Valdés-Mas, Antonio Agraz-Doblás, Rafael Díaz de la Guardia, Jordi Ribera, Lurdes Zamora, Chrystele Bilhou-Nabera, Nassera Abermil, Hélène Guermouche, Elodie Gouache, Guy Leverger, Mario F. Fraga, Agustín F. Fernández, Paola Ballerini, Ignacio Varela, Pablo Menendez
Journal: Blood
Blood (2019) 134 (11): 900–905.
https://doi.org/10.1182/blood.2019000893
Published: 2019
Includes: Supplemental data
Journal Articles

New insights into the biology and origin of mature aggressive B-cell lymphomas by combined epigenomic, genomic, and transcriptional profiling

José I. Martín-Subero, Markus Kreuz, Marina Bibikova, Stefan Bentink, Ole Ammerpohl, Eliza Wickham-Garcia, Maciej Rosolowski, Julia Richter, Lidia Lopez-Serra, Esteban Ballestar, Hilmar Berger, Xabier Agirre, Heinz-Wolfram Bernd, Vincenzo Calvanese, Sergio B. Cogliatti, Hans G. Drexler, Jian-Bing Fan, Mario F. Fraga, Martin L. Hansmann, Michael Hummel, Wolfram Klapper, Bernhard Korn, Ralf Küppers, Roderick A. F. MacLeod, Peter Möller, German Ott, Christiane Pott, Felipe Prosper, Andreas Rosenwald, Carsten Schwaenen, Dirk Schübeler, Marc Seifert, Benjamin Stürzenhofecker, Michael Weber, Swen Wessendorf, Markus Loeffler, Lorenz Trümper, Harald Stein, Rainer Spang, Manel Esteller, David Barker, Dirk Hasenclever, for the Molecular Mechanisms in Malignant Lymphomas Network Project of the Deutsche Krebshilfe, Reiner Siebert
Journal: Blood
Blood (2009) 113 (11): 2488–2497.
https://doi.org/10.1182/blood-2008-04-152900
Published: 2009
Includes: Supplemental data
Journal Articles

The novel DNA methylation inhibitor zebularine is effective against the development of murine T-cell lymphoma

Brief Report
Michel Herranz, Juan Martín-Caballero, Mario F. Fraga, Jesús Ruiz-Cabello, Juana Maria Flores, Manuel Desco, Victor Marquez, Manel Esteller
Journal: Blood
Blood (2006) 107 (3): 1174–1177.
https://doi.org/10.1182/blood-2005-05-2033
Published: 2006
Includes: Supplemental data