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    Alastair L. Smith
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    Journal Articles

    A human genome editing–based MLL :: AF4 ALL model recapitulates key cellular and molecular leukemogenic features

    Clara Bueno, Raul Torres-Ruiz, Talia Velasco-Hernandez, Oscar Molina, Paolo Petazzi, Alba Martinez, Virginia Rodriguez, Meritxell Vinyoles, Sandra Cantilena, Owen Williams, Nerea Vega-Garcia, Sandra Rodriguez-Perales, Jose C. Segovia, Oscar Quintana-Bustamante, Anindita Roy, Claus Meyer, Rolf Marschalek, Alastair L. Smith, Thomas A. Milne, Mario F. Fraga, Juan Ramón Tejedor, Pablo Menéndez
    Journal: Blood
    Blood (2023) 142 (20): 1752–1756.
    https://doi.org/10.1182/blood.2023020858
    Published: 2023
    Includes: Supplemental data
    Journal Articles

    Sustained MYB Activity Is Necessary for Oncogenic Transcription in KMT2A -Rearranged Acute Lymphoblastic Leukemia through Enhancer-Promoter Interactions and Epigenetic Modifications at Enhancers

    I-Jun Lau, Joe R Harman, Nicole E Jackson, Nicholas Denny, Alastair L Smith, Paresh Vyas, James Oliver Davies, Jim Hughes, Nicholas Crump, Thomas Arthur Milne
    Journal: Blood
    Blood (2023) 142 (Supplement 1): 40.
    https://doi.org/10.1182/blood-2023-185172
    Published: 2023

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