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Journal Articles

Off-the-shelf dual CAR-iNKT cell immunotherapy eradicates medullary and leptomeningeal high-risk KMT2A-rearranged leukemia

Open Access
Hongwei Ren, Natalina Elliott, Bryan Lye, Mohammad Umer Sharif Shohan, Joe Wilson Cross, Lucy May Field, Kanagaraju Ponnusamy, Siobhan Rice, Thomas Jackson, Ilia Leontari, Nouhad El Ouazzani, Rebecca Thomas, Sarah Inglott, Jack Bartram, Owen Smith, Professor, Jonathan Bond, Irene Roberts, Christina Halsey, Rachael Bashford-Rogers, Thomas A Milne, Anindita Roy, Anastasios Karadimitris
Journal: Blood
Blood blood.2025029302.
https://doi.org/10.1182/blood.2025029302
Published: 2025
Includes: Supplemental data
Journal Articles

Enhancer heterogeneity in acute lymphoblastic leukemia drives differential gene expression in patients

Open Access
Alastair Smith, Nicholas David Robert Denny, Catherine Chahrour, Kim Sharp, Marta Arachi, Ana Maria Dopico-Fernandez, Natalina Elliott, Joe Harman, Thomas Jackson, Huimin Geng, Owen Smith, Professor, Jonathan Bond, Irene Roberts, Ronald W. W. Stam, Nicholas Crump, James Davies, Anindita Roy, Thomas A Milne
Journal: Blood
Blood blood.2024028019.
https://doi.org/10.1182/blood.2024028019
Published: 2025
Includes: Supplemental data
Journal Articles

Differential Gene Expression in KMT2A::AFF1 Leukemia Is Driven By Enhancer Heterogeneity

Free
Alastair L Smith, Nicholas Denny, Catherine M Chahrour, Natalina Elliott, Thomas Jackson, Joe Harman, Huimin Geng, Irene Roberts, Nicholas Crump, James Oliver Davies, Anindita Roy, Thomas A Milne
Journal: Blood
Blood (2024) 144 (Supplement 1): 201.
https://doi.org/10.1182/blood-2024-208035
Published: 2024
Journal Articles

The Fetal Specific Gene LIN28B Is Essential for Human Fetal B-Lymphopoiesis and Initiation of KMT2A-AFF1+ Infant Acute Lymphoblastic Leukemia

Free
Rebecca E Ling, Thomas Jackson, Natalina Elliott, Joe W Cross, Lucy Hamer, Arundhati S Wuppalapati, Alastair L Smith, Catherine M Chahrour, Okan Sevim, Deena Iskander, Guanlin Wang, Sorcha I O'Byrne, Siobhan Rice, Joe R Harman, Bethan Psaila, Rhys G Morgan, Irene Roberts, Thomas A Milne, Anindita Roy
Journal: Blood
Blood (2024) 144 (Supplement 1): 199.
https://doi.org/10.1182/blood-2024-198819
Published: 2024
Journal Articles

The BET inhibitor CPI203 promotes ex vivo expansion of cord blood long-term repopulating HSCs and megakaryocytes

Free
Brief Report
Peng Hua, Joanna Hester, George Adigbli, Rong Li, Bethan Psaila, Anindita Roy, Carole J. R. Bataille, Graham M. Wynne, Thomas Jackson, Thomas A. Milne, Angela J. Russell, James Davies, Irene Roberts, Fadi Issa, Suzanne M. Watt
Journal: Blood
Blood (2020) 136 (21): 2410–2415.
https://doi.org/10.1182/blood.2020005357
Published: 2020
Includes: Supplemental data