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Journal Articles

Bispecific CAR-iNKT Immunotherapy for High Risk MLL-Rearranged Acute Lymphoblastic Leukemia

Hongwei Ren, Natalina Elliott, Bryan Lye, Joe Cross, Lucy Field, Kanagaraju Ponnusamy, Irene Roberts, Christina Halsey, Thomas Arthur Milne, Anindita Roy, Anastasios Karadimitris

Blood (2023) 142 (Supplement 1): 766.

https://doi.org/10.1182/blood-2023-186442

Published: 2023

Journal Articles

Leukaemia and the CNS Niche: Insights on Bidirectional Communication from a Model of Infant Leukaemia

Alasdair Duguid, Camille Malouf, Vasiliki Symeonidou, Christina Halsey, Katrin Ottersbach

Blood (2022) 140 (Supplement 1): 3038–3039.

https://doi.org/10.1182/blood-2022-160176

Published: 2022

Journal Articles

miR-130b and miR-128a are essential lineage-specific codrivers of t(4;11) MLL-AF4 acute leukemia

Camille Malouf, Eric T. B. Antunes, Michael O’Dwyer, Hélène Jakobczyk, Franziska Sahm, Sophie-Luise Landua, Richard A. Anderson, Abdenour Soufi, Christina Halsey, Katrin Ottersbach

Blood (2021) 138 (21): 2066–2092.

https://doi.org/10.1182/blood.2020006610

Published: 2021

Includes: Supplemental data

Journal Articles

The age of the bone marrow microenvironment influences B-cell acute lymphoblastic leukemia progression via CXCR5-CXCL13

Blood (2021) 138 (19): 1870–1884.

https://doi.org/10.1182/blood.2021011557

Published: 2021

Includes: Multimedia, Supplemental data

Journal Articles

A “Goldilocks” approach to CNS leukemia is needed

Christina Halsey, Gabriele Escherich

Blood (2021) 138 (4): 288–289.

https://doi.org/10.1182/blood.2021011461

Published: 2021

Journal Articles

Stearoyl-CoA Desaturase (SCD) Enhances Central Nervous System Leukemia

Angela Maria Savino, PhD, Orianne Olivares, PhD, Shani Barel, Lev Yakimov, Ifat Geron, Hila Fishman, Inbal Mor, Ifat Abramovich, Sara Isabel Fernandes, Eyal Gottlieb, Christina Halsey, MD PhD, Shai Izraeli, MD

Blood (2018) 132 (Supplement 1): 389.

https://doi.org/10.1182/blood-2018-99-114749

Published: 2018

Journal Articles

Acute Neurotoxicity during ALL Therapy Is Associated with Treatment Intensity, Age and Female Sex - an Analysis of SAE Reports from the UKALL 2003 Trial

Qurat-ul-Ain Wahid, Lina Hamadeh, Sheena McGowan, Rachael Hough, MD BMBS, FRCP, FRCPath, Ajay Vora, MD, Anthony V. Moorman, PhD, Christina Halsey, MD PhD

Blood (2018) 132 (Supplement 1): 1379.

https://doi.org/10.1182/blood-2018-99-113267

Published: 2018

Journal Articles

IL7R is associated with CNS infiltration and relapse in pediatric B-cell precursor acute lymphoblastic leukemia

Ameera Alsadeq, Lennart Lenk, Anila Vadakumchery, Antony Cousins, Christian Vokuhl, Ahmad Khadour, Fotini Vogiatzi, Felix Seyfried, Lueder-Hinrich Meyer, Gunnar Cario, Elias Hobeika, Klaus-Michael Debatin, Christina Halsey, Martin Schrappe, Denis M. Schewe, Hassan Jumaa

Blood (2018) 132 (15): 1614–1617.

https://doi.org/10.1182/blood-2018-04-844209

Published: 2018

Includes: Supplemental data

Journal Articles

Upregulated Cholesterol Biosynthesis Is a Biomarker for Isolated Central Nervous System Relapse in Acute Lymphoblastic Leukaemia

Antony Cousins, Elke Markert, Matilda Degn, PhD, Orianne Olivares, Yasar Mehmood Yousafzai, MBBS,PhD, Saeeda Bhatti, PhD, Pawel Herzyk, Alison M. Michie, PhD BSc, Kjeld Schmiegelow, MD DMSc, Eyal Gottlieb, PhD, Christina Halsey

Blood (2017) 130 (Supplement 1): 3992.

https://doi.org/10.1182/blood.V130.Suppl_1.3992.3992

Published: 2017

Journal Articles

Functional SCD1 Is Critical for Acute Lymphoblastic Leukaemia Maintenance in the Central Nervous System

Orianne Olivares, Antony Cousins, Elke Markert, Sergey Tumanov, Gillian Mackay, Jurre Kamphorst, Karen Keeshan, Pawel Herzyk, Eyal Gottlieb, Christina Halsey

Blood (2017) 130 (Supplement 1): 2608.

https://doi.org/10.1182/blood.V130.Suppl_1.2608.2608

Published: 2017

Journal Articles

The ability to cross the blood–cerebrospinal fluid barrier is a generic property of acute lymphoblastic leukemia blasts

Blood (2016) 127 (16): 1998–2006.

https://doi.org/10.1182/blood-2015-08-665034

Published: 2016

Includes: Supplemental data

Journal Articles

Carma1 Is Important for T-ALL CNS Infiltration and Survival in an Animal Model of T-ALL

Sreenivasa Rao Oruganti, MSc, PhD, Christina Halsey, MDPhD, Savannah Krebsbach, Francois Asperti-Boursin, PhD, Sumit Patel, Ksenia Matlawska-Wasowska, PhD, Stuart S. Winter, MD, Judy Cannon, PhD

Blood (2014) 124 (21): 934.

https://doi.org/10.1182/blood.V124.21.934.934

Published: 2014

Journal Articles

Ras pathway mutations are prevalent in relapsed childhood acute lymphoblastic leukemia and confer sensitivity to MEK inhibition

Julie Irving, Elizabeth Matheson, Lynne Minto, Helen Blair, Marian Case, Christina Halsey, Isabella Swidenbank, Frida Ponthan, Renate Kirschner-Schwabe, Stefanie Groeneveld-Krentz, Jana Hof, James Allan, Christine Harrison, Josef Vormoor, Arend von Stackelberg, Cornelia Eckert

Blood (2014) 124 (23): 3420–3430.

https://doi.org/10.1182/blood-2014-04-531871

Published: 2014

Includes: Supplemental data

Journal Articles

Interleukin-15 enhances cellular proliferation and upregulates CNS homing molecules in pre-B acute lymphoblastic leukemia

Mark T. S. Williams, Yasar Yousafzai, Charlotte Cox, Allison Blair, Ruaidhrí Carmody, Shuji Sai, Karen E. Chapman, Rachel McAndrew, Angela Thomas, Alison Spence, Brenda Gibson, Gerard J. Graham, Christina Halsey

Blood (2014) 123 (20): 3116–3127.

https://doi.org/10.1182/blood-2013-05-499970

Published: 2014

Includes: Supplemental data

Journal Articles

An Analysis Of Mechanisms Of Central Nervous System Infiltration In Acute Lymphoblastic Leukaemia Using Primary Cells Xenografted Into Immunodeficient Mice

Blood (2013) 122 (21): 3866.

https://doi.org/10.1182/blood.V122.21.3866.3866

Published: 2013

Journal Articles

RAS Pathway Mutations Are Highly Prevalent In Relapsed Childhood Acute Lymphoblastic Leukaemia, Are Frequently Relapse-Drivers and Confer Sensitivity To MEK Inhibition

Julie Irving, PhD, Elizabeth C. Matheson, MPhil, Lynne Minto, Helen Blair, PhD, Marian Case, MSc, Christina Halsey, MD, PhD, Isabella Swidenbank, MRes, Frida Ponthan, PhD, Renate Kirschner-Schwabe, PhD, Stefanie Groeneveld-Krentz, MSc, Jana Hof, MSc, James Allan, PhD, Christine J. Harrison, PhD, Josef Vormoor, MD, Arend Stackelberg, MD, Cornelia Eckert, PhD

Blood (2013) 122 (21): 823.

https://doi.org/10.1182/blood.V122.21.823.823

Published: 2013

Journal Articles

Central Nervous System Involvement in a Xenograft Model of Pre-B Acute Lymphoblastic Leukaemia Is Associated with Dysfunctional CXCR4 Expression and Upregulation of the Neurotropic Chemokine Receptors CCR6 and CX3CR1,

Christina Halsey, MD, PhD, Mark TS Williams, PhD, Yasar Yousafzai, MD, Klaus Rehe, MD, Olaf Heidenreich, PhD, Josef Vormoor, MD, Brenda Gibson, Gerard Graham, PhD

Blood (2011) 118 (21): 3449.

https://doi.org/10.1182/blood.V118.21.3449.3449

Published: 2011

Journal Articles

Role of GATA-1s in early hematopoiesis and differences between alternative splicing in human and murine GATA-1

Christina Halsey, Oliver Tunstall, Brenda Gibson, Irene Roberts, Gerard Graham

Blood (2010) 115 (16): 3415–3416.

https://doi.org/10.1182/blood-2010-02-267930

Published: 2010

Journal Articles

A Novel Therapeutic Approach in Triosephosphate Isomerase Deficiency.

Christina Halsey, Solomon A. Ndoni, Roya Babaei-Jadidi, David Roper, Barbara J. Wild, Tom J. Vulliamy, Paul J. Thornalley, Mark Layton

Blood (2006) 108 (11): 3735.

https://doi.org/10.1182/blood.V108.11.3735.3735

Published: 2006

Journal Articles

Analysis of GATA-1 Mutations in Chronic Myeloid Leukaemia.

Christina Halsey, Chris Fisher, Brenda Gibson, Paresh Vyas, Gerry Graham

Blood (2006) 108 (11): 4774.

https://doi.org/10.1182/blood.V108.11.4774.4774

Published: 2006

NARROW

Bispecific CAR-iNKT Immunotherapy for High Risk MLL-Rearranged Acute Lymphoblastic Leukemia

Leukaemia and the CNS Niche: Insights on Bidirectional Communication from a Model of Infant Leukaemia

miR-130b and miR-128a are essential lineage-specific codrivers of t(4;11) MLL-AF4 acute leukemia

The age of the bone marrow microenvironment influences B-cell acute lymphoblastic leukemia progression via CXCR5-CXCL13

A “Goldilocks” approach to CNS leukemia is needed

Stearoyl-CoA Desaturase (SCD) Enhances Central Nervous System Leukemia

Acute Neurotoxicity during ALL Therapy Is Associated with Treatment Intensity, Age and Female Sex - an Analysis of SAE Reports from the UKALL 2003 Trial

IL7R is associated with CNS infiltration and relapse in pediatric B-cell precursor acute lymphoblastic leukemia

Upregulated Cholesterol Biosynthesis Is a Biomarker for Isolated Central Nervous System Relapse in Acute Lymphoblastic Leukaemia

Functional SCD1 Is Critical for Acute Lymphoblastic Leukaemia Maintenance in the Central Nervous System

The ability to cross the blood–cerebrospinal fluid barrier is a generic property of acute lymphoblastic leukemia blasts

Carma1 Is Important for T-ALL CNS Infiltration and Survival in an Animal Model of T-ALL

Ras pathway mutations are prevalent in relapsed childhood acute lymphoblastic leukemia and confer sensitivity to MEK inhibition

Interleukin-15 enhances cellular proliferation and upregulates CNS homing molecules in pre-B acute lymphoblastic leukemia

An Analysis Of Mechanisms Of Central Nervous System Infiltration In Acute Lymphoblastic Leukaemia Using Primary Cells Xenografted Into Immunodeficient Mice

RAS Pathway Mutations Are Highly Prevalent In Relapsed Childhood Acute Lymphoblastic Leukaemia, Are Frequently Relapse-Drivers and Confer Sensitivity To MEK Inhibition

Central Nervous System Involvement in a Xenograft Model of Pre-B Acute Lymphoblastic Leukaemia Is Associated with Dysfunctional CXCR4 Expression and Upregulation of the Neurotropic Chemokine Receptors CCR6 and CX3CR1,

Role of GATA-1s in early hematopoiesis and differences between alternative splicing in human and murine GATA-1

A Novel Therapeutic Approach in Triosephosphate Isomerase Deficiency.

Analysis of GATA-1 Mutations in Chronic Myeloid Leukaemia.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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