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Journal Articles

Single-Cell Genomics Details the Maturation Block in BCP-ALL and Identifies Therapeutic Vulnerabilities in DUX4 -Rearranged Cases

Hanna Thorsson, Rasmus Henningsson, Noelia Puente-Moncada, Ludvig Sjöström, Helena Ågerstam, Pablo Enrique Peña-Martínez, Carl Sandén, Marianne Rissler, Anders Castor, Hanne Vibeke Marquart, Signe Modvig, Kajsa Paulsson, Cornelis Pronk, Kjeld Schmiegelow, Axel Hyrenius Wittsten, Christina Orsmark-Pietras, Henrik PhD Lilljebjörn, Thoas Fioretos

Blood (2023) 142 (Supplement 1): 842.

https://doi.org/10.1182/blood-2023-173350

Published: 2023

Journal Articles

STAG2/LMO2 Gamma-Delta (γδ) T-ALL: Identification and Characterization of an Extremely High Risk Group of T-ALL in the Very Young

Shunsuke Kimura, Petri Pölönen, Lindsey Montefiori, Kenneth Caldwell, Ilaria Iacobucci, Chelsey Chen, Anthony Brown, Katie Han, Yen-Chun Liu, Yunchao Chang, Zhongshan Cheng, Zhou Yinmei, Chun Shik Park, Sharnise Mitchell, Noemi Reyes, Allen Yeoh, Andishe Attarbaschi, Andrew Moore, Atsushi Manabe, Barbara Buldini, Kean Hui Chiew, Chi Kong Li, Ching-Hon Pui, Chunxu Qu, Daisuke Tomizawa, Elisabeth Paietta, Franco Locatelli, Gabriele Escherich, Gao Qingsong, Hannah Elisa Muhle, Hanne Vibeke Marquart, Hester A. de Groot-Kruseman, Jacob M. Rowe, Jan Stary, Jan Trka, John Kim Choi, Jules P.P. Meijerink, Junko Takita, Katarzyna Pawinska-Wasikowska, Kjeld Schmiegelow, Mariko Eguchi, Martin Schrappe, Martin Zimmermann, Masatoshi Takagi, Melissa Maybury, Michael Svaton, Michaela Reiterova, Michal Kicinski, Motohiro Kato, Orietta Spinelli, Pauline Mazilier, Paul G. Thomas, Riccardo Masetti, Rishi Sury Kotecha, Rob Pieters, Sarah Elitzur, Selina M Luger, Shuhong Shen, Sima Jeha, Steven M. Kornblau, Szymon Skoczen, Takako Miyamura, Tiffaney Vincent, Toshihiko Imamura, Valentino Conter, Yanjing Tang, Zhaohui Gu, Kathryn G. Roberts, David T. Teachey, Kristine R Crews, Cheng Cheng, Jun J. Yang, Hiroto Inaba, Charles G. Mullighan

Blood (2023) 142 (Supplement 1): 845.

https://doi.org/10.1182/blood-2023-178688

Published: 2023

Journal Articles

Single-Cell Transcriptomics Points to a Role of Stemness and Bone Marrow Niche Interactions in the Poor Response to Induction Therapy in T-Cell Acute Lymphoblastic Leukemia

Signe Modvig, Hanna Thorsson, Bodil Als-Nielsen, Claus Christensen, Nina Friesgaard Øbro, Hans O. Madsen, Henrik Lilljebjörn, Kjeld Schmiegelow, Thoas Fioretos, Hanne Vibeke Marquart

Blood (2023) 142 (Supplement 1): 4345.

https://doi.org/10.1182/blood-2023-188631

Published: 2023

Journal Articles

Gut Microbiome Links to Disease Stage and Immune Microenvironment in Patients with Chronic Lymphocytic Leukemia

Tereza Faitova, Caspar Da Cunha-Bang, Hans Jakob Hartling, Jakob Thaning Bay, Hanne Vibeke Marquart, Arnon P. Kater, Mark-David Levin, Sabina Kersting, Carsten Utoft Niemann, Rebecka Svanberg

Blood (2023) 142 (Supplement 1): 6515.

https://doi.org/10.1182/blood-2023-186158

Published: 2023

Journal Articles

Single Cell Multi-Omic Profiling of Acute Lymphoblastic Leukemia Identifies Altered Cellular Pathways and Highlights Heterogeneity in the Maturation Block of DUX4 -Rearranged ALL

Hanna Thorsson, Rasmus Henningsson, Noelia Puente-Moncada, Carl Sandén, Signe Modvig, Marianne Rissler, Kajsa Paulsson, Anders Castor, Cornelis Jan Pronk, Hanne Vibeke Marquart, Kjeld Schmiegelow, Christina Orsmark-Pietras, Henrik Lilljebjörn, Thoas Fioretos

Blood (2022) 140 (Supplement 1): 3467–3468.

https://doi.org/10.1182/blood-2022-163031

Published: 2022

Journal Articles

Bone Marrow Plasma Proteome Analysis By Differential Ultracentrifugation and Tandem Mass Spectrometry Allow for Characterization of Leukemia-Derived Extracellular Vesicles in Patients with Acute Lymphoblastic Leukemia

Ole Østergaard, Hanne Vibeke Marquart, Maria Thastrup, Christian Mirian, Bodil Als-Nielsen, Kjeld Schmiegelow, Jesper V Olsen, Signe Modvig

Blood (2022) 140 (Supplement 1): 3473–3474.

https://doi.org/10.1182/blood-2022-166141

Published: 2022

Journal Articles

The Molecular Landscape of KMT2A -Rearranged Leukemia from Infancy to Adulthood Reveals Age and Leukemia-Specific Mutational Patterns

Blood (2021) 138 (Supplement 1): 3479.

https://doi.org/10.1182/blood-2021-152082

Published: 2021

Journal Articles

Relapse risk following truncation of pegylated asparaginase in childhood acute lymphoblastic leukemia

Sofie Gottschalk Højfeldt, Kathrine Grell, Jonas Abrahamsson, Bendik Lund, Kim Vettenranta, Ólafur G. Jónsson, Thomas L. Frandsen, Benjamin O. Wolthers, Hanne Vibeke Marquart, Goda Vaitkeviciene, Kristi Lepik, Mats Heyman, Kjeld Schmiegelow, Birgitte Klug Albertsen

Blood (2021) 137 (17): 2373–2382.

https://doi.org/10.1182/blood.2020006583

Published: 2021

Includes: Supplemental data

Journal Articles

Value of Flow Cytometry for MRD-Based Relapse Prediction in B-Cell Precursor Acute Lymphoblastic Leukemia in a Multi-Center Setting

Blood (2019) 134 (Supplement_1): 2755.

https://doi.org/10.1182/blood-2019-122311

Published: 2019

Journal Articles

A Comprehensive Study of Human Integrins in Pediatric Lymphoblastic Leukemia Supports a Role of CD49f (Integrin α6) in the Localization to Bone Marrow but Not Spinal Fluid

Bibi F. S. S. Scharff, Signe Modvig, MD PhD, Maria Thastrup, PhD, Mette Levinsen, PhD, Matilda Degn, PhD, Lars Peter Ryder, MSc, Kjeld Schmiegelow, Professor MD DMSc., Claus René Lykke Christensen, MSc, MSc.Eng, PhD, Hanne Vibeke Marquart, MD PhD

Blood (2019) 134 (Supplement_1): 5205.

https://doi.org/10.1182/blood-2019-126701

Published: 2019

Journal Articles

Intensive Chemotherapy for High-Risk ALL in Children - the Nordic Collaborative Approach

Atte Nikkilä, MD, Olli Lohi, MD PhD, Ólafur Gísli Jónsson, MD PhD, Bendik Lund, MD PhD, Jonas Abrahamsson, Goda Elizabeta Vaitkeviciene, MD PhD, Kaie Pruunsild, MD, Mats Heyman, MD PhD, Hanne Vibeke Marquart, MD PhD, Kim Vettenranta, MD PhD, Kjeld Schmiegelow, MD PhD

Blood (2019) 134 (Supplement_1): 742.

https://doi.org/10.1182/blood-2019-122914

Published: 2019

Journal Articles

Improved Relapse-Free Survival and Overall Survival in Patients with High Immune Reconstitution of Gamma Delta T Cells 2 Months after Allogeneic Hematopoietic Stem Cell Transplantation

Lia Minculescu, MD, Hanne Vibeke Marquart, MD PhD, Lars Peter Ryder, MSc, PhD, Ida Schjødt, MD PhD, Lone Smidstrup Friis, MD PhD, Brian Thomas Kornblit, MD PhD, Søren Lykke Petersen, MD DMSc., Niels Smedegaard Andersen, MD PhD, Eva Kannik Hastrup, MD PhD, Anne Fischer-Nielsen, MD PhD, Henrik Sengeloev, MD DMSc

Blood (2018) 132 (Supplement 1): 3396.

https://doi.org/10.1182/blood-2018-99-111777

Published: 2018

Journal Articles

Central Nervous System Involvement Detected By Flow Cytometry Is a Risk Factor for Relapse in Childhood Acute Lymphoblastic Leukemia

Maria Thastrup, PhD, Hanne Vibeke Marquart, MD PhD, Mette Levinsen, PhD, Kathrine Grell, PhD, Jonas Abrahamsson, Birgitte Klug Albertsen, MD, Thomas Leth Frandsen, MD PhD, Arja Harila-Saari, MD Associate professor, Päivi Maria Lähteenmäki, MD PhD, Riitta Niinimäki, MD, Cornelis Jan Pronk, MD PhD, Aina Ulvmoen, PhD, Goda Vaitkeviciene, MD, Mervi Taskinen, MD PhD, Kjeld Schmiegelow, MD DMSc

Blood (2018) 132 (Supplement 1): 657.

https://doi.org/10.1182/blood-2018-99-114173

Published: 2018

Journal Articles

International cooperative study identifies treatment strategy in childhood ambiguous lineage leukemia

Blood (2018) 132 (3): 264–276.

https://doi.org/10.1182/blood-2017-12-821363

Published: 2018

Includes: Supplemental data

Journal Articles

Assessing the Subclonal Genetic Landscape of KMT2A -Rearranged Infant Acute Lymphoblastic Leukemia By Single-Cell Genomics

Mattias Pilheden, MSc, Axel Hyrenius Wittsten, MSc, Veronica Gonzalez-Pena, PhD, Helena Sturesson, PhD, Michael P Walsh, PhD, Guangchun Song, PhD, Hanne Vibeke Marquart, MD PhD, Birgitte Lausen, MD PhD, Anders Castor, MD PhD, Jinghui Zhang, PhD, James R. Downing, MD, Jing Ma, PhD, Charles Gawad, MD PhD, Anna K. Andersson, PhD

Blood (2017) 130 (Supplement 1): 2709.

https://doi.org/10.1182/blood.V130.Suppl_1.2709.2709

Published: 2017

Journal Articles

Flow Cytometry Based MRD Monitoring Is an Accurate Risk Stratification Tool in Acute T-Lymphoblastic Leukemia

Signe Modvig, MD PhD, Hans O Madsen, Sanna M. Siitonen, MD PhD, Susanne Rosthøj, PhD, Vesa Juvonen, PhD, Liv T. N. Osnes, MD PhD, Helen Vålerhaugen, Magnus Hultdin, MD PhD, M Marincevic, PhD, Reda Matuzeviciene, MD PhD, Mindaugas Stoskus, Aili Lilleorg, PhD, Nina Toft, MD PhD, Ólafur G. Jónsson, MD, Kjeld Schmiegelow, MD, Hanne Vibeke Marquart, MD PhD

Blood (2017) 130 (Supplement 1): 372.

https://doi.org/10.1182/blood.V130.Suppl_1.372.372

Published: 2017

Journal Articles

High Expression of Legumain in Pediatric B-Cell Precursor Acute Lymphoblastic Leukemia Is Associated with Central Nervous System Involvement

Maria Jeppesen, Mette Levinsen, MD, Nicolas Rapin, PhDMSc, Line Groth-Pedersen, PhD, Kristina Aluzaite, Birgitte Klug Albertsen, MD, Rehannah Borup, PhD, Thomas Leth Frandsen, MD PhD, Hans O Madsen, Hanne Vibeke Marquart, MD PhD, Steen Rosthøj, Bibi F. S. S. Scharff, Peder S. Wehner, Bo Porse, PhD, Kjeld Schmiegelow, MD DMSc

Blood (2017) 130 (Supplement 1): 3990.

https://doi.org/10.1182/blood.V130.Suppl_1.3990.3990

Published: 2017

Journal Articles

Individualized 6-Mercaptopurine Increments in Consolidation Treatment of Childhood Acute Lymphoblastic Leukemia: A NOPHO ALL2008 Randomized Controlled Trial

Morten Tulstrup, MD, Thomas Leth Frandsen, MD PhD, Jonas Abrahamsson, MD PhD, Bendik Lund, MD PhD, Kim Vettenranta, MD PhD, Olafur G. Jonsson, MD PhD, Hanne Vibeke Marquart, MD PhD, Birgitte Klug Albertsen, MD, Mats Heyman, MD PhD, Kjeld Schmiegelow, MD

Blood (2017) 130 (Supplement 1): 142.

https://doi.org/10.1182/blood.V130.Suppl_1.142.142

Published: 2017

Journal Articles

An Immature Immunophenotype (CD34pos, CD38dim, nTdTdim) on Malignant B-Cell Precursor Blasts at Diagnosis Predicts High Minimal Residual Disease in BCP-ALL

Signe Modvig, MD PhD, Nina Friesgaard Øbro, PhD, Susanne Rosthøj, PhD, Gitte W Jürgensen, MD, Kjeld Schmiegelow, MD DMSc, Hanne Vibeke Marquart, MD PhD

Blood (2016) 128 (22): 1728.

https://doi.org/10.1182/blood.V128.22.1728.1728

Published: 2016

Journal Articles

Acute Leukemia of Ambiguous Lineage: A Comprehensive Survival Analysis Enables Designing New Treatment Strategies

Ondrej Hrusak, MD PhD, Valerie De Haas, MD PhD, Ales Luks, Iveta Janotova, Ester Mejstrikova, MD PhD, Kirsten Bleckmann, MD, Anja Moricke, MD, Julie Irving, PhD, Benigna Konatkowska, Thomas B. Alexander, MD MPH, Hiroto Inaba, MD PhD, Kjeld Schmiegelow, MD DMSc, Simone Stokley, FRCPath,, Jorge Gabriel Rossi, PhD, Maria Sara Felice, MD PhD, Luciano Dalla-Pozza, MB BS FRACP, Jessa Morales, Michael Dworzak, MD, Barbara Buldini, MD, Giuseppe Basso, Myriam Campbell, Maria Elena Cabrera, Neda Marinov, Sarah Elitzur, MD, Shai Izraeli, MD, Drorit Luria, PhD, Tamar Feuerstein, PhD, Alexandra Kolenova, MD PhD, Peter Svec, Elena Kreminska, Karen R. Rabin, MD, Sophia Polychronopoulou, MD PhD, Elaine da Costa, Hanne Vibeke Marquart, MD PhD, Antonis Kattamis, MD, Richard Ratei, Dirk Reinhardt, MD PhD, Anthony V Moorman, PhD, Martin Schrappe, MD, Jan Stary, MD D.Sc.

Blood (2016) 128 (22): 584.

https://doi.org/10.1182/blood.V128.22.584.584

Published: 2016

NARROW

Single-Cell Genomics Details the Maturation Block in BCP-ALL and Identifies Therapeutic Vulnerabilities in DUX4 -Rearranged Cases

STAG2/LMO2 Gamma-Delta (γδ) T-ALL: Identification and Characterization of an Extremely High Risk Group of T-ALL in the Very Young

Single-Cell Transcriptomics Points to a Role of Stemness and Bone Marrow Niche Interactions in the Poor Response to Induction Therapy in T-Cell Acute Lymphoblastic Leukemia

Gut Microbiome Links to Disease Stage and Immune Microenvironment in Patients with Chronic Lymphocytic Leukemia

Single Cell Multi-Omic Profiling of Acute Lymphoblastic Leukemia Identifies Altered Cellular Pathways and Highlights Heterogeneity in the Maturation Block of DUX4 -Rearranged ALL

Bone Marrow Plasma Proteome Analysis By Differential Ultracentrifugation and Tandem Mass Spectrometry Allow for Characterization of Leukemia-Derived Extracellular Vesicles in Patients with Acute Lymphoblastic Leukemia

The Molecular Landscape of KMT2A -Rearranged Leukemia from Infancy to Adulthood Reveals Age and Leukemia-Specific Mutational Patterns

Relapse risk following truncation of pegylated asparaginase in childhood acute lymphoblastic leukemia

Value of Flow Cytometry for MRD-Based Relapse Prediction in B-Cell Precursor Acute Lymphoblastic Leukemia in a Multi-Center Setting

A Comprehensive Study of Human Integrins in Pediatric Lymphoblastic Leukemia Supports a Role of CD49f (Integrin α6) in the Localization to Bone Marrow but Not Spinal Fluid

Intensive Chemotherapy for High-Risk ALL in Children - the Nordic Collaborative Approach

Improved Relapse-Free Survival and Overall Survival in Patients with High Immune Reconstitution of Gamma Delta T Cells 2 Months after Allogeneic Hematopoietic Stem Cell Transplantation

Central Nervous System Involvement Detected By Flow Cytometry Is a Risk Factor for Relapse in Childhood Acute Lymphoblastic Leukemia

International cooperative study identifies treatment strategy in childhood ambiguous lineage leukemia

Assessing the Subclonal Genetic Landscape of KMT2A -Rearranged Infant Acute Lymphoblastic Leukemia By Single-Cell Genomics

Flow Cytometry Based MRD Monitoring Is an Accurate Risk Stratification Tool in Acute T-Lymphoblastic Leukemia

High Expression of Legumain in Pediatric B-Cell Precursor Acute Lymphoblastic Leukemia Is Associated with Central Nervous System Involvement

Individualized 6-Mercaptopurine Increments in Consolidation Treatment of Childhood Acute Lymphoblastic Leukemia: A NOPHO ALL2008 Randomized Controlled Trial

An Immature Immunophenotype (CD34pos, CD38dim, nTdTdim) on Malignant B-Cell Precursor Blasts at Diagnosis Predicts High Minimal Residual Disease in BCP-ALL

Acute Leukemia of Ambiguous Lineage: A Comprehensive Survival Analysis Enables Designing New Treatment Strategies

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American Society of Hematology

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American Society of Hematology

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