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Journal Articles

Single-cell genomics details the maturation block in BCP-ALL and identifies therapeutic vulnerabilities in DUX4 -r cases

Hanna Thorsson, Rasmus Henningsson, Noelia Puente-Moncada, Pablo Peña-Martínez, Ludvig Sjöström, Helena Ågerstam, Carl Sandén, Marianne Rissler, Anders Castor, Hanne Marquart, Signe Modvig, Kajsa Paulsson, Cornelis Jan Pronk, Kjeld Schmiegelow, Axel Hyrenius-Wittsten, Christina Orsmark-Pietras, Henrik Lilljebjörn, Thoas Fioretos

Blood (2024) 144 (13): 1399–1411.

https://doi.org/10.1182/blood.2023021705

Published: 2024

Includes: Supplemental data

Journal Articles

The 3D Chromatin Landscape of B-Cell Precursor Childhood Acute Lymphoblastic Leukemia

Larissa Helena Moura-Castro, Minjun Yang, Eleanor Woodward, Anders Castor, Thoas Fioretos, Bertil Johansson, Marcus Järås, Anna Hagström, Kajsa Paulsson

Blood (2023) 142 (Supplement 1): 4151.

https://doi.org/10.1182/blood-2023-178491

Published: 2023

Journal Articles

Constitutional and Somatic Variants in ARID5B in Pediatric B-Cell Precursor Acute Lymphoblastic Leukemia

Charlotte Ragnarsson, Minjun Yang, Larissa Helena Moura-Castro, Rebeqa Gunnarsson, Linda Olsson-Arvidsson, Nicolas Duployez, Marketa Zaliova, Jan Zuna, Anders Castor, Bertil Johansson, Kajsa Paulsson

Blood (2023) 142 (Supplement 1): 5736.

https://doi.org/10.1182/blood-2023-179488

Published: 2023

Journal Articles

Single-Cell Genomics Details the Maturation Block in BCP-ALL and Identifies Therapeutic Vulnerabilities in DUX4 -Rearranged Cases

Hanna Thorsson, Rasmus Henningsson, Noelia Puente-Moncada, Ludvig Sjöström, Helena Ågerstam, Pablo Enrique Peña-Martínez, Carl Sandén, Marianne Rissler, Anders Castor, Hanne Vibeke Marquart, Signe Modvig, Kajsa Paulsson, Cornelis Pronk, Kjeld Schmiegelow, Axel Hyrenius Wittsten, Christina Orsmark-Pietras, Henrik PhD Lilljebjörn, Thoas Fioretos

Blood (2023) 142 (Supplement 1): 842.

https://doi.org/10.1182/blood-2023-173350

Published: 2023

Journal Articles

The Relapse Mechanisms and Genomic Landscape Differ in KMT2A -r Pediatric Leukemia in Relation to Relapse Time

Louise Ahlgren, Mattias Pilheden, Helena Sturesson, Varsha Singh, Qirui Zhang, Michael Walsh, Guangchun Song, Anders Castor, Cornelis Jan Pronk, Pauline Schneider, Ronald W. Stam, Gisela Barbany, Katja Pokrovskaja Tamm, Jonas Abrahamsson, Linda Fogelstrand, Olli Lohi, Jing Ma, Jinghui Zhang, Anna K. Hagstroem-Andersson

Blood (2023) 142 (Supplement 1): 2978.

https://doi.org/10.1182/blood-2023-185044

Published: 2023

Journal Articles

Single Cell Multi-Omic Profiling of Acute Lymphoblastic Leukemia Identifies Altered Cellular Pathways and Highlights Heterogeneity in the Maturation Block of DUX4 -Rearranged ALL

Hanna Thorsson, Rasmus Henningsson, Noelia Puente-Moncada, Carl Sandén, Signe Modvig, Marianne Rissler, Kajsa Paulsson, Anders Castor, Cornelis Jan Pronk, Hanne Vibeke Marquart, Kjeld Schmiegelow, Christina Orsmark-Pietras, Henrik Lilljebjörn, Thoas Fioretos

Blood (2022) 140 (Supplement 1): 3467–3468.

https://doi.org/10.1182/blood-2022-163031

Published: 2022

Journal Articles

The Rise and Fall of Leukemia Clones in Longitudinal Samples from Diagnosis to Relapse in KMT2A- rearranged Infant and Childhood Leukemia

Louise Ahlgren, Mattias Pilheden, Helena Sturesson, Varsha Singh, Qirui Zhang, Anders Castor, Cornelis Jan Pronk, Gisela Barbany, Katja Pokrovskaja Tamm, Linda Fogelstrand, Michael P Walsh, Guangchun Song, Jinghui Zhang, Jing Ma, Anna Hagstroem-Andersson

Blood (2022) 140 (Supplement 1): 9189–9190.

https://doi.org/10.1182/blood-2022-165869

Published: 2022

Journal Articles

The Molecular Landscape of KMT2A -Rearranged Leukemia from Infancy to Adulthood Reveals Age and Leukemia-Specific Mutational Patterns

Blood (2021) 138 (Supplement 1): 3479.

https://doi.org/10.1182/blood-2021-152082

Published: 2021

Journal Articles

A Treatment Protocol with Imatinib and Intensive Chemotherapy for Pediatric Philadelphia Positive Acute Lymphoblastic Leukemia Patients: A Single-Arm, Intergroup Study (EsPhALL 2010-2014)

Andrea Biondi, MD, Virginie Gandemer, MDPhD, Myriam Campbell, MD, Anders Castor, MD PhD, Rob Pieters, MD PhD, Paola De Lorenzo, PhD, Veronica Leoni, MD, Jan Stary, Gabriele Escherich, MD, Chi Kong Li, MD, Giovanni Cazzaniga, PhD, Helene Cave, PharmD, PhD, Silja Roettgers, PhD, Valentino Conter, MD, Vaskar Saha, MD PhD, Martin Schrappe, MD PhD, Maria Grazia Valsecchi, PhD

Blood (2017) 130 (Supplement 1): 97.

https://doi.org/10.1182/blood.V130.Suppl_1.97.97

Published: 2017

Journal Articles

Assessing the Subclonal Genetic Landscape of KMT2A -Rearranged Infant Acute Lymphoblastic Leukemia By Single-Cell Genomics

Mattias Pilheden, MSc, Axel Hyrenius Wittsten, MSc, Veronica Gonzalez-Pena, PhD, Helena Sturesson, PhD, Michael P Walsh, PhD, Guangchun Song, PhD, Hanne Vibeke Marquart, MD PhD, Birgitte Lausen, MD PhD, Anders Castor, MD PhD, Jinghui Zhang, PhD, James R. Downing, MD, Jing Ma, PhD, Charles Gawad, MD PhD, Anna K. Andersson, PhD

Blood (2017) 130 (Supplement 1): 2709.

https://doi.org/10.1182/blood.V130.Suppl_1.2709.2709

Published: 2017

Journal Articles

Comprehensive Genetic Characterization of Pediatric T-Cell Acute Lymphoblastic Leukemia

Kristina Karrman, MD PhDstudent, Anders Castor, Mikael Behrendtz, MD, Erik Forestier, Linda Olsson, PhDstudent, Mats Ehinger, MD PhD, Andrea Biloglav, Thoas Fioretos, MD PhD, Kajsa Paulsson, MSc, PhD, Bertil Johansson, MD PhD

Blood (2014) 124 (21): 1084.

https://doi.org/10.1182/blood.V124.21.1084.1084

Published: 2014

Journal Articles

Comparison of MRD Monitoring By IG/TR Rearrangement and BCR/ABL1 Transcript in Ph+ Pediatric Acute Lymphoblastic Leukemia Patients Treated with Imatinib in the Esphall Study

Blood (2014) 124 (21): 3782.

https://doi.org/10.1182/blood.V124.21.3782.3782

Published: 2014

Journal Articles

Role of MRD in Ph+ Pediatric Acute Lymphoblastic Leukemia Patients Treated with and without Tirosine Kinase Inhibitor in the Esphall Study

Giovanni Cazzaniga, Martin Schrappe, Paola de Lorenzo, Anders Castor, Giovanna Lucchini, Virginie Gandemer, Rob Pieters, MD, PhD, Jan Stary, Gabriele Escherich, Jeremy Hancock, Maurizio Arico', Silja Röttgers, Vaskar Saha, Andrea Biondi, MD, Maria Grazia Valsecchi

Blood (2012) 120 (21): 1467.

https://doi.org/10.1182/blood.V120.21.1467.1467

Published: 2012

Journal Articles

Efficacy and Safety of Imatinib on Top of BFM-Like Chemotherapy in Pediatric Patients with Ph+/BCR-ABL+ Acute Lymphoblastic Leukemia (Ph+ALL). the EsPhALL Study

Andrea Biondi, MD, Martin Schrappe, MD, Paola Di Lorenzo, Anders Castor, Giovanna Lucchini, Virginie Gandemer, Rob Pieters, Jan Stary, M.D., Gabriele Escherich, Myriam Campbell, Ci Kong-Li, Ajay J Vora, Gudmar Lonnerholm, Maurizio Arico‘, Jochen Harbott, Vaskar Saha, Maria Grazia Valsecchi

Blood (2011) 118 (21): 873.

https://doi.org/10.1182/blood.V118.21.873.873

Published: 2011

Journal Articles

Selective Persistence of Distinct Stem/B Leukaemic Stem Cells In Childhood Acute Lymphoblastic Leukaemia In Clinical Remission.

Christoph Lutz, MD, Petter Woll, PhD, Anders Castor, MD, PhD, Helen Ferry, PhD, Christina Jensen, PhD, Joanne Green, Helene Dreau, Michael Lutteropp, Anna Schuh, MD, PhD, Georgina Hall, MD, PhD, Chris Mitchell, MD, PhD, Jan Zuna, MD, PhD, Veronica Buckle, PhD, Sten Eirik W Jacobsen, MD, PhD, Tariq Enver, PhD

Blood (2010) 116 (21): 1585.

https://doi.org/10.1182/blood.V116.21.1585.1585

Published: 2010

Journal Articles

High GATA-2 expression inhibits human hematopoietic stem and progenitor cell function by effects on cell cycle

Alex J. Tipping, Cristina Pina, Anders Castor, Dengli Hong, Neil P. Rodrigues, Lorenza Lazzari, Gillian E. May, Sten Eirik W. Jacobsen, Tariq Enver

Blood (2009) 113 (12): 2661–2672.

https://doi.org/10.1182/blood-2008-06-161117

Published: 2009

Includes: Supplemental data

Journal Articles

Protein kinase B (c-akt) regulates hematopoietic lineage choice decisions during myelopoiesis

Miranda Buitenhuis, Liesbeth P. Verhagen, Hanneke W. M. van Deutekom, Anders Castor, Sandra Verploegen, Leo Koenderman, Sten-Eirik W. Jacobsen, Paul J. Coffer

Blood (2008) 111 (1): 112–121.

https://doi.org/10.1182/blood-2006-07-037572

Published: 2008

Includes: Supplemental data

Journal Articles

Haploidentical Peripheral Blood Stem Cell Transplantation for Relapsing/Refractory Neuroblastoma.

Jacek Toporski, Helga Björgvinsdóttir, Anders Castor, Josefina Dykes-Horwath, Mikael Garkavij, Solveig Hafsteinsdóttir, Jesper Heldrup, Lars Hjorth, Gunnar Juliusson, Helena Mörse, Charlotta Schaedel, Stefan Scheding, Jan Tenvall, Thomas Wiebe, Albert N. Bekassy

Blood (2006) 108 (11): 5420.

https://doi.org/10.1182/blood.V108.11.5420.5420

Published: 2006

Journal Articles

Enforced Expression of GATA-2 Confers Quiescence on Human Hematopoietic Stem and Progenitor Cells In Vitro and In Vivo .

Alex J. Tipping, Cristina Pina, Anders Castor, Ann Atzberger, Dengli Hong, Lorenza Lazzari, Gillian May, Sten Eirik Jacobsen, Tariq Enver

Blood (2006) 108 (11): 83.

https://doi.org/10.1182/blood.V108.11.83.83

Published: 2006

Journal Articles

Differential regulation of granulopoiesis by the basic helix-loop-helix transcriptional inhibitors Id1 and Id2

Miranda Buitenhuis, Hanneke W. M. van Deutekom, Liesbeth P. Verhagen, Anders Castor, Sten Eirik W. Jacobsen, Jan-Willem J. Lammers, Leo Koenderman, Paul J. Coffer

Blood (2005) 105 (11): 4272–4281.

https://doi.org/10.1182/blood-2004-12-4883

Published: 2005

NARROW

Single-cell genomics details the maturation block in BCP-ALL and identifies therapeutic vulnerabilities in DUX4 -r cases

The 3D Chromatin Landscape of B-Cell Precursor Childhood Acute Lymphoblastic Leukemia

Constitutional and Somatic Variants in ARID5B in Pediatric B-Cell Precursor Acute Lymphoblastic Leukemia

Single-Cell Genomics Details the Maturation Block in BCP-ALL and Identifies Therapeutic Vulnerabilities in DUX4 -Rearranged Cases

The Relapse Mechanisms and Genomic Landscape Differ in KMT2A -r Pediatric Leukemia in Relation to Relapse Time

Single Cell Multi-Omic Profiling of Acute Lymphoblastic Leukemia Identifies Altered Cellular Pathways and Highlights Heterogeneity in the Maturation Block of DUX4 -Rearranged ALL

The Rise and Fall of Leukemia Clones in Longitudinal Samples from Diagnosis to Relapse in KMT2A- rearranged Infant and Childhood Leukemia

The Molecular Landscape of KMT2A -Rearranged Leukemia from Infancy to Adulthood Reveals Age and Leukemia-Specific Mutational Patterns

A Treatment Protocol with Imatinib and Intensive Chemotherapy for Pediatric Philadelphia Positive Acute Lymphoblastic Leukemia Patients: A Single-Arm, Intergroup Study (EsPhALL 2010-2014)

Assessing the Subclonal Genetic Landscape of KMT2A -Rearranged Infant Acute Lymphoblastic Leukemia By Single-Cell Genomics

Comprehensive Genetic Characterization of Pediatric T-Cell Acute Lymphoblastic Leukemia

Comparison of MRD Monitoring By IG/TR Rearrangement and BCR/ABL1 Transcript in Ph+ Pediatric Acute Lymphoblastic Leukemia Patients Treated with Imatinib in the Esphall Study

Role of MRD in Ph+ Pediatric Acute Lymphoblastic Leukemia Patients Treated with and without Tirosine Kinase Inhibitor in the Esphall Study

Efficacy and Safety of Imatinib on Top of BFM-Like Chemotherapy in Pediatric Patients with Ph+/BCR-ABL+ Acute Lymphoblastic Leukemia (Ph+ALL). the EsPhALL Study

Selective Persistence of Distinct Stem/B Leukaemic Stem Cells In Childhood Acute Lymphoblastic Leukaemia In Clinical Remission.

High GATA-2 expression inhibits human hematopoietic stem and progenitor cell function by effects on cell cycle

Protein kinase B (c-akt) regulates hematopoietic lineage choice decisions during myelopoiesis

Haploidentical Peripheral Blood Stem Cell Transplantation for Relapsing/Refractory Neuroblastoma.

Enforced Expression of GATA-2 Confers Quiescence on Human Hematopoietic Stem and Progenitor Cells In Vitro and In Vivo .

Differential regulation of granulopoiesis by the basic helix-loop-helix transcriptional inhibitors Id1 and Id2

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American Society of Hematology

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