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Gabriele Escherich
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Journal Articles

Pediatric T-cell lymphoblastic lymphomas but not leukemias harbor TRB :: NOTCH1 fusions with unfavorable outcome

Brief Report
Marcel te Vrugt, Janna Wessolowski, Gerrit Randau, Amelie Alfert, Stephanie Mueller, Kenneth Scholten, Claudia Sopalla, Claudia Lanvers-Kaminsky, Marc Hotfilder, Finn Lamp, Christine Damm-Welk, Jette Luedersen, Gabriele Escherich, Udo zur Stadt, Lena Behrmann, Wilhelm Woessmann, Ilske Oschlies, Matteo Marzi, Martin Zimmermann, Birgit Burkhardt
Journal: Blood
Blood (2024) 144 (13): 1412–1417.
https://doi.org/10.1182/blood.2024025307
Published: 2024
Includes: Supplemental data
Journal Articles

ATM germ line pathogenic variants affect outcomes in children with ataxia-telangiectasia and hematological malignancies

Clinical Trials & Observations
Sarah Elitzur, Ruth Shiloh, Jan L. C. Loeffen, Agata Pastorczak, Masatoshi Takagi, Simon Bomken, Andre Baruchel, Thomas Lehrnbecher, Sarah K. Tasian, Oussama Abla, Nira Arad-Cohen, Itziar Astigarraga, Miriam Ben-Harosh, Nicole Bodmer, Triantafyllia Brozou, Francesco Ceppi, Liliia Chugaeva, Luciano Dalla Pozza, Stephane Ducassou, Gabriele Escherich, Roula Farah, Amber Gibson, Henrik Hasle, Julieta Hoveyan, Elad Jacoby, Janez Jazbec, Stefanie Junk, Alexandra Kolenova, Jelena Lazic, Luca Lo Nigro, Nizar Mahlaoui, Lane Miller, Vassilios Papadakis, Lucie Pecheux, Marta Pillon, Ifat Sarouk, Jan Stary, Eftichia Stiakaki, Marion Strullu, Thai Hoa Tran, Marek Ussowicz, Jaime Verdu-Amoros, Anna Wakulinska, Joanna Zawitkowska, Dominique Stoppa-Lyonnet, A. Malcolm Taylor, Yosef Shiloh, Shai Izraeli, Veronique Minard-Colin, Kjeld Schmiegelow, Ronit Nirel, Andishe Attarbaschi, Arndt Borkhardt
Journal: Blood
Blood (2024) 144 (11): 1193–1205.
https://doi.org/10.1182/blood.2024024283
Published: 2024
Includes: Supplemental data
Journal Articles

The IL-7R antagonist lusvertikimab reduces leukemic burden in xenograft ALL via antibody-dependent cellular phagocytosis

Lennart Lenk, Irène Baccelli, Anna Laqua, Julia Heymann, Claas Reimer, Anna Dietterle, Dorothee Winterberg, Caroline Mary, Frédérique Corallo, Julien Taurelle, Emma Narbeburu, Stéphanie Neyton, Mylène Déramé, Sabrina Pengam, Fotini Vogiatzi, Beat Bornhauser, Jean-Pierre Bourquin, Simon Raffel, Vladyslava Dovhan, Thomas Schüler, Gabriele Escherich, Monique L. den Boer, Judith M. Boer, Wiebke Wessels, Matthias Peipp, Julia Alten, Željko Antić, Anke K. Bergmann, Martin Schrappe, Gunnar Cario, Monika Brüggemann, Nicolas Poirier, Denis M. Schewe
Journal: Blood
Blood (2024) 143 (26): 2735–2748.
https://doi.org/10.1182/blood.2023021088
Published: 2024
Includes: Supplemental data
Journal Articles

Tyrosine kinase inhibitor response of ABL-class acute lymphoblastic leukemia: the role of kinase type and SH3 domain

Inge van Outersterp, Sarah K. Tasian, Caitlin E. J. Reichert, Aurélie Boeree, Hester A. de Groot-Kruseman, Gabriele Escherich, Judith M. Boer, Monique L. den Boer
Journal: Blood
Blood (2024) 143 (21): 2178–2189.
https://doi.org/10.1182/blood.2023023120
Published: 2024
Includes: Supplemental data
Journal Articles

Project Evolve, Evaluation of Lineage Switch (LS), an International Initiative: Preliminary Results Reveal Dismal Outcomes in Patients with LS

Sara K. Silbert, Cynthia Harrison, D. Nathan Biery, Alexandra Semchenkova, Elena Zerkalenkova, Anna Alonso-Saladrigues, Kaylyn Utley, Ibrahim Aldoss, Liping Zhao, Sneha Fernandes, Jeremy D. Rubinstein, Naomi Torres Carapia, Bill H. Chang, Anant Vatsayan, Barbara De Moerloose, Holly L. Pacenta, Dennis John Kuo, Gabriele Escherich, Benjamin J. Lee, Michele S. Redell, Mandi R. Fitzjohn, Daniel P. Larson, Nicolas Duployez, Raymund S. Cuevo, Rui Rochelle He, David Dickens, Firas El Chaer, Kelly Reed, Matthias Wolfl, Sunil S. Raikar, Süreyya Savaşan, Latika Puri, Zhubin J. Gahvari, Aimee C. Talleur, Hisham Abdel-Azim, Aghiad Chamdin, Marlie R.M. Provost, Vanessa A. Fabrizio, Kerstin Mezger, Alexandra McLean Stevens, Emily M. Hsieh, Hao-Wei Wang, Constance M. Yuan, Ulrich A. Duffner, Jing Pan, Sara Ghorashian, Susana Rives, Chloe Hoang, Kara L. Davis, Elad Jacoby, Alexander Popov, Adam Lamble, Nirali N. Shah
Journal: Blood
Blood (2023) 142 (Supplement 1): 4202.
https://doi.org/10.1182/blood-2023-182293
Published: 2023
Journal Articles

STAG2/LMO2 Gamma-Delta (γδ) T-ALL: Identification and Characterization of an Extremely High Risk Group of T-ALL in the Very Young

Shunsuke Kimura, Petri Pölönen, Lindsey Montefiori, Kenneth Caldwell, Ilaria Iacobucci, Chelsey Chen, Anthony Brown, Katie Han, Yen-Chun Liu, Yunchao Chang, Zhongshan Cheng, Zhou Yinmei, Chun Shik Park, Sharnise Mitchell, Noemi Reyes, Allen Yeoh, Andishe Attarbaschi, Andrew Moore, Atsushi Manabe, Barbara Buldini, Kean Hui Chiew, Chi Kong Li, Ching-Hon Pui, Chunxu Qu, Daisuke Tomizawa, Elisabeth Paietta, Franco Locatelli, Gabriele Escherich, Gao Qingsong, Hannah Elisa Muhle, Hanne Vibeke Marquart, Hester A. de Groot-Kruseman, Jacob M. Rowe, Jan Stary, Jan Trka, John Kim Choi, Jules P.P. Meijerink, Junko Takita, Katarzyna Pawinska-Wasikowska, Kjeld Schmiegelow, Mariko Eguchi, Martin Schrappe, Martin Zimmermann, Masatoshi Takagi, Melissa Maybury, Michael Svaton, Michaela Reiterova, Michal Kicinski, Motohiro Kato, Orietta Spinelli, Pauline Mazilier, Paul G. Thomas, Riccardo Masetti, Rishi Sury Kotecha, Rob Pieters, Sarah Elitzur, Selina M Luger, Shuhong Shen, Sima Jeha, Steven M. Kornblau, Szymon Skoczen, Takako Miyamura, Tiffaney Vincent, Toshihiko Imamura, Valentino Conter, Yanjing Tang, Zhaohui Gu, Kathryn G. Roberts, David T. Teachey, Kristine R Crews, Cheng Cheng, Jun J. Yang, Hiroto Inaba, Charles G. Mullighan
Journal: Blood
Blood (2023) 142 (Supplement 1): 845.
https://doi.org/10.1182/blood-2023-178688
Published: 2023
Journal Articles

Novel Insights in TKI Resistance in BCR :: ABL1 -Positive B-Cell Acute Lymphoblastic Leukemia Beyond Kinase Domain Mutations

Inge Van Outersterp, Caitlin E.J. Reichert, Aurelie Boeree, Cesca Van De Ven, Brian Kruisinga, Hester A. de Groot-Kruseman, Gabriele Escherich, Anita W. Rijneveld, Judith M. Boer, Monique L. den Boer
Journal: Blood
Blood (2023) 142 (Supplement 1): 1615.
https://doi.org/10.1182/blood-2023-179704
Published: 2023
Journal Articles

Secondary Lesions and Sensitivity to Signaling Inhibitors of Pediatric iAMP21 B-Cell Precursor Acute Lymphoblastic Leukemia

Anna Ostergaard, Femke M. Hormann, Stijn Van Den Broek, Aurelie Boeree, Cesca Van De Ven, Gabriele Escherich, Edwin Sonneveld, Judith M. Boer, Monique L. Den Boer
Journal: Blood
Blood (2023) 142 (Supplement 1): 1613.
https://doi.org/10.1182/blood-2023-179719
Published: 2023
Journal Articles

Multinational Retrospective Analysis of Bridging Therapy Prior to Chimeric Antigen Receptor T Cells for Relapsed/Refractory Acute Lymphoblastic Leukemia in Children and Young Adults

Maike Breidenbach, Peter Bader, Andishe Attarbaschi, Claudia Rossig, Roland Meisel, Markus Metzler, Marion Subklewe, Fabian Mueller, Paul-Gerhardt Schlegel, Irene Teichert von Lüttichau, Jean-Pierre Bourquin, Gabriele Escherich, Gunnar Cario, Peter Lang, Ramona Krauss, Arend von Stackelberg, Semjon Willier, Christina Peters, Tobias Feuchtinger
Journal: Blood
Blood (2023) 142 (Supplement 1): 2135.
https://doi.org/10.1182/blood-2023-190117
Published: 2023
Journal Articles

Treatment of Molecular Relapses in Pediatric AML Saves Toxicities Prior to Hematopoietic Stem Cell Transplantation (HSCT) - Results of AMoRe2017 Trial

Amelie Polutta, Dirk Reinhardt, Andre Baruchel, Henrik Hasle, Franco Locatelli, C. Michel Zwaan, Michael Frühwald, Silke Westphal, Michael Dworzak, Heidrun Boztug, Gabriele Escherich, Thomas Lehrnbecher, Bianca F. Goemans, Brigitte Strahm, Markus Schneider, Lina Hoffmeister, Katharina Waack
Journal: Blood
Blood (2023) 142 (Supplement 1): 1521.
https://doi.org/10.1182/blood-2023-180820
Published: 2023
Journal Articles

ATM Germline Pathogenic Variants Affect Treatment Outcomes in Children with Acute Lymphoblastic Leukemia/Lymphoma and Ataxia Telangiectasia

Sarah Elitzur, Ruth Shiloh, Jan Loeffen, Agata Pastorczak, Masatoshi Takagi, Simon Bomken, Andre Baruchel, Stephane Ducassou, Nizar Mahlaoui, Marion Strullu, Thomas Lehrnbecher, Kjeld Schmiegelow, Oussama Abla, Liliia Anderzhanova, Nira Arad-Cohen, Itziar Astigarraga, Miriam Ben-Harosh, Francesco Ceppi, Nicole Bodmer, Triantafyllia Brozou, Luciano Dalla-Pozza, Gabriele Escherich, Roula Farah, Amber Gibson, Henrik Hasle, Julieta Hoveyan, Elad Jacoby, Janez Jazbec, Alexandra Kolenova, Jelena Lazic, Luca Lo Nigro, Lane Miller, Vassilios Papadakis, Lucie Pecheux, Marta Pillon, Ifat Sarouk, Jan Stary, Eftichia Stiakaki, Sarah K. Tasian, Thai Hoa Tran, Marek Ussowicz, Jose Jaime Verdu-Amoros, Anna Wakulinska, Joanna Zawitkowska, Dominique Stoppa-Lyonnet, Malcolm Taylor, Yosef Shiloh, Shai Izraeli, Ronit Nirel, Veronique Minard-Colin, Andishe Attarbaschi, Arndt Borkhardt
Journal: Blood
Blood (2023) 142 (Supplement 1): 520.
https://doi.org/10.1182/blood-2023-179333
Published: 2023
Journal Articles

EBV-driven lymphoid neoplasms associated with pediatric ALL maintenance therapy

Clinical Trials & Observations
Sarah Elitzur, Ajay Vora, Birgit Burkhardt, Hiroto Inaba, Andishe Attarbaschi, Andre Baruchel, Gabriele Escherich, Brenda Gibson, Hsi-Che Liu, Mignon Loh, Anthony V. Moorman, Anja Möricke, Rob Pieters, Anne Uyttebroeck, Susan Baird, Jack Bartram, Shlomit Barzilai-Birenboim, Sandeep Batra, Miriam Ben-Harosh, Yves Bertrand, Trudy Buitenkamp, Kenneth Caldwell, Ricardo Drut, Ashley V. Geerlinks, Gil Gilad, John Grainger, Stephanie Haouy, Nicholas Heaney, Mary Huang, Danielle Ingham, Zdenka Krenova, Michaela Kuhlen, Thomas Lehrnbecher, Atsushi Manabe, Felix Niggli, Claudia Paris, Shoshana Revel-Vilk, Pierre Rohrlich, Mohamad G. Sinno, Tomasz Szczepanski, Melanie Tamesberger, Rajasekharan Warrier, Matthias Wolfl, Ronit Nirel, Shai Izraeli, Arndt Borkhardt, Kjeld Schmiegelow
Journal: Blood
Blood (2023) 141 (7): 743–755.
https://doi.org/10.1182/blood.2022016975
Published: 2023
Includes: Supplemental data
Journal Articles

The Prognostic Effect of IKZF1 Deletions in ETV6 :: RUNX1 and High Hyperdiploid Childhood Acute Lymphoblastic Leukemia

Anna Østergaard, Amir Enshaei, Rob Pieters, Ajay Vora, Martin A. Horstmann, Gabriele Escherich, Bertil Johansson, Mats Heyman, Kjeld Schmiegelow, Peter M. Hoogerbrugge, Monique L. den Boer, Roland P. Kuiper, Anthony V. Moorman, Judith M. Boer, Frank N van Leeuwen
Journal: Blood
Blood (2022) 140 (Supplement 1): 3483–3485.
https://doi.org/10.1182/blood-2022-157431
Published: 2022
Journal Articles

Remission, treatment failure, and relapse in pediatric ALL: an international consensus of the Ponte-di-Legno Consortium

Clinical Trials & Observations
Swantje Buchmann, Martin Schrappe, Andre Baruchel, Andrea Biondi, Michael Borowitz, Myriam Campbell, Gunnar Cario, Giovanni Cazzaniga, Gabriele Escherich, Christine J. Harrison, Mats Heyman, Stephen P. Hunger, Csongor Kiss, Hsi-Che Liu, Franco Locatelli, Mignon L. Loh, Atsushi Manabe, Georg Mann, Rob Pieters, Ching-Hon Pui, Susana Rives, Kjeld Schmiegelow, Lewis B. Silverman, Jan Stary, Ajay Vora, Patrick Brown
Journal: Blood
Blood (2022) 139 (12): 1785–1793.
https://doi.org/10.1182/blood.2021012328
Published: 2022
Includes: Supplemental data
Journal Articles

A Phase 2 Study to Test the Feasibility, Safety and Efficacy of the Addition of Blinatumomab to the Interfant06 Backbone in Infants with Newly Diagnosed KMT2A -Rearranged Acute Lymphoblastic Leukemia. a Collaborative Study of the Interfant Network

Inge M. Van Der Sluis, Paola De Lorenzo, Rishi Sury Kotecha, Andishe Attarbaschi, Gabriele Escherich, Karsten Nysom, Jan Stary, Alina Ferster, Benoit Brethon, Phillip Ancliff, Andrea Biondi, Maria Grazia Valsecchi, Rob Pieters
Journal: Blood
Blood (2021) 138 (Supplement 1): 361.
https://doi.org/10.1182/blood-2021-144843
Published: 2021
Journal Articles

A Meta-Analysis of Hypersensitivity to Pegylated Escherichia coli Asparaginase Used As First-Line Treatment in Contemporary Pediatric Acute Lymphoblastic Leukemia Protocols

Leiah Brigitha, Marta Fiocco, Rob Pieters, Birgitte Klug Albertsen, Gabriele Escherich, Elixabet Lopez-Lopez, Veerle Mondelaers, Ajay Vora, Lynda M. Vrooman, Kjeld Schmiegelow, Inge M. Van Der Sluis
Journal: Blood
Blood (2021) 138 (Supplement 1): 2308.
https://doi.org/10.1182/blood-2021-144674
Published: 2021
Journal Articles

Minimal Residual Disease and Outcome Characteristics in Infant KMT2A-Germline Acute Lymphoblastic Leukemia Treated on the Interfant-06 Protocol

Janine Stutterheim, Paola De Lorenzo, Inge M. Van Der Sluis, Julia Alten, Philip Ancliffe, Andishe Attarbaschi, Luis Alberto Aversa, Judith M. Boer, Andrea Biondi, Benoit Brethon, Paulina Diaz, Giovanni Gazzaniga, Gabriele Escherich, Alina Ferster, Rishi S Kotecha, Birgitte Lausen, Alex WK Leung, Franco Locatelli, Lewis B. Silverman, Jan Stary, Tomasz Szczepanski, Vincent H.J. Van Der Velden, Ajay Vora, Jan Zuna, Martin Schrappe, Maria Grazia Valsecchi, Rob Pieters
Journal: Blood
Blood (2021) 138 (Supplement 1): 2383.
https://doi.org/10.1182/blood-2021-145058
Published: 2021
Journal Articles

TP53 and KRAS Variants at Initial Diagnosis Identify an Ultra-High Risk Group of Pediatric T-Lymphoblastic Leukemia (T-ALL)

Tamara Kempter, Joachim B. Kunz, Paulina Richter-Pechanska, Katarzyna Tomska, Tobias Rausch, Busra Erarslan-Uysal, Cornelia Eckert, Martin Zimmermann, Martin Stanulla, Martin Schrappe, Gunnar Cario, Gabriele Escherich, Renate Kirschner-Schwabe, Martina U. Muckenthaler, Jan O. Korbel, Andreas E. Kulozik
Journal: Blood
Blood (2021) 138 (Supplement 1): 1315.
https://doi.org/10.1182/blood-2021-148420
Published: 2021
Journal Articles

A “Goldilocks” approach to CNS leukemia is needed

Christina Halsey, Gabriele Escherich
Journal: Blood
Blood (2021) 138 (4): 288–289.
https://doi.org/10.1182/blood.2021011461
Published: 2021
Journal Articles

SSBP2-CSF1R is a recurrent fusion in B-lineage acute lymphoblastic leukemia with diverse genetic presentation and variable outcome

Claire Schwab, Kathryn Roberts, Judith M. Boer, Gudrun Göhring, Doris Steinemann, Ajay Vora, Christine Macartney, Rachael Hough, Zoe Thorn, Richard Dillon, Gabriele Escherich, Giovanni Cazzaniga, Brigitte Schlegelberger, Mignon Loh, Monique L. den Boer, Anthony V. Moorman, Christine J. Harrison
Journal: Blood
Blood (2021) 137 (13): 1835–1838.
https://doi.org/10.1182/blood.2020008536
Published: 2021
Includes: Supplemental data