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Journal Articles

The Prognostic Effect of IKZF1 Deletions in ETV6 :: RUNX1 and High Hyperdiploid Childhood Acute Lymphoblastic Leukemia

Anna Østergaard, Amir Enshaei, Rob Pieters, Ajay Vora, Martin A. Horstmann, Gabriele Escherich, Bertil Johansson, Mats Heyman, Kjeld Schmiegelow, Peter M. Hoogerbrugge, Monique L. den Boer, Roland P. Kuiper, Anthony V. Moorman, Judith M. Boer, Frank N van Leeuwen

Blood (2022) 140 (Supplement 1): 3483–3485.

https://doi.org/10.1182/blood-2022-157431

Published: 2022

Journal Articles

Clofarabine Significantly Increases Eradication of Minimal Residual Disease of B-Precursor ALL Compared to High-Dose Cytarabine in Randomized Trial Coall 08-09

Gabriele Escherich, MD, Udo Zur Stadt, PhD, Dagmar Dilloo, MD, Joerg Faber, MD PhD, Tobias Feuchtinger, MD, Thomas Imscheiler, MD, Norbert Jorch, MD, Arnulf Pekrun, Irene Schmid, MD, Martin Zimmermann, PhD, Martin A. Horstmann, MD

Blood (2020) 136 (Supplement 1): 21.

https://doi.org/10.1182/blood-2020-136149

Published: 2020

Journal Articles

A validated novel continuous prognostic index to deliver stratified medicine in pediatric acute lymphoblastic leukemia

Blood (2020) 135 (17): 1438–1446.

https://doi.org/10.1182/blood.2019003191

Published: 2020

Includes: Supplemental data

Journal Articles

Amsacrine, Etoposide and Methylprednisolone As Part of the Therapy Intensification in Children with Acute Lymphoblastic Leukemia: A Retrospective Analysis in the Trial Coall 08-09

Gabriele Escherich, Katharina Wos, MD, Franziska Schramm, MD, Martin A. Horstmann, MD

Blood (2018) 132 (Supplement 1): 5168.

https://doi.org/10.1182/blood-2018-99-112623

Published: 2018

Journal Articles

TIM-3 Expression on CD4 + Bone Marrow T Cells Predicts Relapse of Pediatric B-Precursor Acute Lymphoblastic Leukemia

Franziska Blaeschke, MD, Semjon Willier, MD, Dana Stenger, Mareike Lepenies, Martin A. Horstmann, MD, Gabriele Escherich, Martin Zimmermann, PhD, Theresa Kaeuferle, PhD, Meino Rohlfs, PhD, Irene Schmid, MD, Michael H. Albert, MD, Vera Binder, MD, Christoph Klein, MD PhD, Tobias Feuchtinger, MD

Blood (2018) 132 (Supplement 1): 2833.

https://doi.org/10.1182/blood-2018-99-118376

Published: 2018

Journal Articles

Rapid Capture NGS Identifies Genomic Rearrangements in BCP-ALL for MRD Diagnostics

Udo Zur Stadt, PhD, Malik Alawi, M. Sc., Gabriele Escherich, MD, Martin A. Horstmann, MD

Blood (2017) 130 (Supplement 1): 2715.

https://doi.org/10.1182/blood.V130.Suppl_1.2715.2715

Published: 2017

Journal Articles

Daunorubicin during Delayed Intensification Considerably Lowers the Incidence of Infectious Complications but Might Result in Decreased Disease-Free Survival Compared to Adriamycin in Children with Acute Lymphoblastic Leukemia - a Randomized Comparison in Trial Coall 08-09.

Gabriele Escherich, MD, Franziska Schramm, MD, Martin Zimmermann, PhD, Martin A. Horstmann, MD

Blood (2017) 130 (Supplement 1): 2599.

https://doi.org/10.1182/blood.V130.Suppl_1.2599.2599

Published: 2017

Journal Articles

JAK2 Aberrations in Childhood B-Cell Precursor Acute Lymphoblastic Leukemia

Elisabeth M.P. Steeghs, MSc, Isabel S. Jerchel, MSc, Willemieke de Goffau-Nobel, MSc, Alex Q. Hoogkamer, BSc, Judith M. Boer, PhD, Aurélie Boeree, BSc, Cesca van de Ven, PhD, Marco J. Koudijs, PhD, Nicolle J.M. Besselink, BSc, Hester A. de Groot-Kruseman, PhD, C. Michel Zwaan, MD PhD, Martin A. Horstmann, MD, Rob Pieters, MD PhD, Monique L. Den Boer, PhD

Blood (2016) 128 (22): 583.

https://doi.org/10.1182/blood.V128.22.583.583

Published: 2016

Journal Articles

RAS Pathway Mutations As Predictive Biomarker for Treatment Adaptation in Pediatric B-Cell Precursor Acute Lymphoblastic Leukemia

Isabel S. Jerchel, MSc, Alex Q. Hoogkamer, BSc, Ingrid M. Ariës, PhD, Elisabeth M.P. Steeghs, MSc, Judith M. Boer, PhD, Nicolle J.M. Besselink, BSc, Aurélie Boeree, BSc, Cesca van de Ven, PhD, Hester A. de Groot-Kruseman, PhD, Valerie De Haas, MD PhD, Martin A. Horstmann, MD, Gabriele Escherich, MD, Ronald W. Stam, PhD, C. Michel Zwaan, MD PhD, Edwin Cuppen, PhD, Marco J. Koudijs, PhD, Rob Pieters, MD PhD, Monique L. Den Boer, MSc, PhD

Blood (2016) 128 (22): 4087.

https://doi.org/10.1182/blood.V128.22.4087.4087

Published: 2016

Journal Articles

Constitutive Activation of FLT3 Is a Positive Prognostic Factor in Infants with MLL-Rearranged Acute Lymphoblastic Leukemia

Henning Fedders, PhD, Denis Martin Schewe, MD, Martin Zimmermann, PhD, Ameera Alsadeq, PhD, Anja Moericke, MD, Udo zur Stadt, PhD, Martin A. Horstmann, MD, Rob Pieters, MD PhD, Martin Schrappe, MD PhD, Gunnar Cario, MD, Martin Stanulla, MD

Blood (2015) 126 (23): 1417.

https://doi.org/10.1182/blood.V126.23.1417.1417

Published: 2015

Journal Articles

Rapid Capture Targeted Next Generation Sequencing (NGS) for Detection of Genomic Kinase- and Cytokine-Receptor Rearrangements in B-Precursor Acute Lymphoblastic Leukemia

Gabriele Escherich, MD, Udo zur Stadt, PhD, Malik Alawi, Martin A. Horstmann, MD

Blood (2015) 126 (23): 2609.

https://doi.org/10.1182/blood.V126.23.2609.2609

Published: 2015

Journal Articles

Prognostic Value of Rare IKZF1 deletions in Childhood B-Cell Precursor Acute Lymphoblastic Leukemia: An International Collaborative Study

Blood (2014) 124 (21): 368.

https://doi.org/10.1182/blood.V124.21.368.368

Published: 2014

Journal Articles

PTEN microdeletions in T-cell acute lymphoblastic leukemia are caused by illegitimate RAG-mediated recombination events

Rui D. Mendes, Leonor M. Sarmento, Kirsten Canté-Barrett, Linda Zuurbier, Jessica G. C. A. M. Buijs-Gladdines, Vanda Póvoa, Willem K. Smits, Miguel Abecasis, J. Andres Yunes, Edwin Sonneveld, Martin A. Horstmann, Rob Pieters, João T. Barata, Jules P. P. Meijerink

Blood (2014) 124 (4): 567–578.

https://doi.org/10.1182/blood-2014-03-562751

Published: 2014

Includes: Supplemental data

Journal Articles

Epigenetic Dysregulation Of ZNF423 Impedes B-Cell Differentiation and Is Linked To Adverse Outcome Of Childhood B-Precursor ALL

Ann-Christin Puller, MSc, Lena Harder, PhD, Martin Zimmermann, PhD, Carol Stocking, PhD, Martin A. Horstmann, MD

Blood (2013) 122 (21): 3745.

https://doi.org/10.1182/blood.V122.21.3745.3745

Published: 2013

Journal Articles

BCR-ABL1 -Like Cases In Pediatric Acute Lymphoblastic Leukemia: A Comparison Between COG/St. Jude and Dutch DCOG Signatures

Judith M. Boer, PhD, João R.M. Marchante, MSc, Martin A. Horstmann, MD, Gabriele Escherich, MD, William E. Evans, PharmD, Rob Pieters, MD, PhD, Monique L. Den Boer

Blood (2013) 122 (21): 2633.

https://doi.org/10.1182/blood.V122.21.2633.2633

Published: 2013

Journal Articles

Key Nodes In FLT3 Dependent Signaling Determine Growth and Survival Of Childhood Acute Lymphoblastic Leukemia

Kevin Dierck, PhD, Ina Siekmann, MSc, Sebastian Prall, PhD, Florian Beck, MSc, Irmela Jeremias, MD, Albert Sickmann, PhD, Martin A. Horstmann, MD

Blood (2013) 122 (21): 2508.

https://doi.org/10.1182/blood.V122.21.2508.2508

Published: 2013

Journal Articles

EMP1, a Novel Poor Prognostic Factor In Pediatric Leukemia Regulates Prednisolone Resistance, Cellular Proliferation, Migration and Adhesion

Ingrid M. Ariës, MSc, Rosanna van den Dungen, BASc, Isabel S. Jerchel, MSc, Lieke C. van den Berk, PhD, Judith M. Boer, PhD, Martin A. Horstmann, MD, Gabriele Escherich, MD, Rob Pieters, Monique L. Den Boer

Blood (2013) 122 (21): 616.

https://doi.org/10.1182/blood.V122.21.616.616

Published: 2013

Journal Articles

Independent prognostic value of BCR-ABL1-like signature and IKZF1 deletion, but not high CRLF2 expression, in children with B-cell precursor ALL

Arian van der Veer, Esmé Waanders, Rob Pieters, Marieke E. Willemse, Simon V. Van Reijmersdal, Lisa J. Russell, Christine J. Harrison, William E. Evans, Vincent H. J. van der Velden, Peter M. Hoogerbrugge, Frank Van Leeuwen, Gabriele Escherich, Martin A. Horstmann, Leila Mohammadi Khankahdani, Dimitris Rizopoulos, Hester A. De Groot-Kruseman, Edwin Sonneveld, Roland P. Kuiper, Monique L. Den Boer

Blood (2013) 122 (15): 2622–2629.

https://doi.org/10.1182/blood-2012-10-462358

Published: 2013

Includes: Supplemental data

Journal Articles

Highly Sensitive Bioluminescence in Vivo Imaging Enables Individualized Preclinical Treatment Trials On Patients ALL Tumor Cells Growing in Mice.

Nadia Terziyska, Catarina Castro Alves, Manfred Ogris, Ernst Wagner, Renier J Brentjens, MD, PhD, Martin A. Horstmann, MD, Leticia Quintanilla-Martinez, MD, PhD, Irmela Jeremias, MD

Blood (2012) 120 (21): 2602.

https://doi.org/10.1182/blood.V120.21.2602.2602

Published: 2012

Journal Articles

Clofarabine in the Frontline Treatment of Childhood Acute Lymphoblastic Leukemia. Results of the COALL 08–09 Study Regarding Safety and Efficacy of Clofarabine in Combination with Asparaginase During Consolidation Therapy.

Gabriele Escherich, MD, Martin Zimmermann, PhD, Martin A. Horstmann, MD

Blood (2012) 120 (21): 2606.

https://doi.org/10.1182/blood.V120.21.2606.2606

Published: 2012

NARROW

The Prognostic Effect of IKZF1 Deletions in ETV6 :: RUNX1 and High Hyperdiploid Childhood Acute Lymphoblastic Leukemia

Clofarabine Significantly Increases Eradication of Minimal Residual Disease of B-Precursor ALL Compared to High-Dose Cytarabine in Randomized Trial Coall 08-09

A validated novel continuous prognostic index to deliver stratified medicine in pediatric acute lymphoblastic leukemia

Amsacrine, Etoposide and Methylprednisolone As Part of the Therapy Intensification in Children with Acute Lymphoblastic Leukemia: A Retrospective Analysis in the Trial Coall 08-09

TIM-3 Expression on CD4 + Bone Marrow T Cells Predicts Relapse of Pediatric B-Precursor Acute Lymphoblastic Leukemia

Rapid Capture NGS Identifies Genomic Rearrangements in BCP-ALL for MRD Diagnostics

Daunorubicin during Delayed Intensification Considerably Lowers the Incidence of Infectious Complications but Might Result in Decreased Disease-Free Survival Compared to Adriamycin in Children with Acute Lymphoblastic Leukemia - a Randomized Comparison in Trial Coall 08-09.

JAK2 Aberrations in Childhood B-Cell Precursor Acute Lymphoblastic Leukemia

RAS Pathway Mutations As Predictive Biomarker for Treatment Adaptation in Pediatric B-Cell Precursor Acute Lymphoblastic Leukemia

Constitutive Activation of FLT3 Is a Positive Prognostic Factor in Infants with MLL-Rearranged Acute Lymphoblastic Leukemia

Rapid Capture Targeted Next Generation Sequencing (NGS) for Detection of Genomic Kinase- and Cytokine-Receptor Rearrangements in B-Precursor Acute Lymphoblastic Leukemia

Prognostic Value of Rare IKZF1 deletions in Childhood B-Cell Precursor Acute Lymphoblastic Leukemia: An International Collaborative Study

PTEN microdeletions in T-cell acute lymphoblastic leukemia are caused by illegitimate RAG-mediated recombination events

Epigenetic Dysregulation Of ZNF423 Impedes B-Cell Differentiation and Is Linked To Adverse Outcome Of Childhood B-Precursor ALL

BCR-ABL1 -Like Cases In Pediatric Acute Lymphoblastic Leukemia: A Comparison Between COG/St. Jude and Dutch DCOG Signatures

Key Nodes In FLT3 Dependent Signaling Determine Growth and Survival Of Childhood Acute Lymphoblastic Leukemia

EMP1, a Novel Poor Prognostic Factor In Pediatric Leukemia Regulates Prednisolone Resistance, Cellular Proliferation, Migration and Adhesion

Independent prognostic value of BCR-ABL1-like signature and IKZF1 deletion, but not high CRLF2 expression, in children with B-cell precursor ALL

Highly Sensitive Bioluminescence in Vivo Imaging Enables Individualized Preclinical Treatment Trials On Patients ALL Tumor Cells Growing in Mice.

Clofarabine in the Frontline Treatment of Childhood Acute Lymphoblastic Leukemia. Results of the COALL 08–09 Study Regarding Safety and Efficacy of Clofarabine in Combination with Asparaginase During Consolidation Therapy.

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American Society of Hematology

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American Society of Hematology

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