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Judith M. Boer
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Journal Articles

Mutational and transcriptional landscape of pediatric B-cell precursor lymphoblastic lymphoma

Emma Kroeze, Ingram Iaccarino, Michelle M. Kleisman, Mayukh Mondal, Thomas Beder, Mouhamad Khouja, Marc P. Höppner, Marijn A. Scheijde-Vermeulen, Lennart A. Kester, Monika Brüggemann, Claudia D. Baldus, Gunnar Cario, Reno S. Bladergroen, Nathalie Garnier, Andishe Attarbaschi, Jaime Verdu-Amorós, Rosemary Sutton, Elizabeth Macintyre, Kenneth Scholten, Laura Arias Padilla, Birgit Burkhardt, Auke Beishuizen, Monique L. den Boer, Roland P. Kuiper, Jan L. C. Loeffen, Judith M. Boer, Wolfram Klapper
Journal: Blood
Blood (2024) 144 (1): 74–83.
https://doi.org/10.1182/blood.2024023938
Published: 2024
Includes: Supplemental data
Journal Articles

When InO says no: understanding escape

Judith M. Boer, C. Michel Zwaan
Journal: Blood
Blood (2024) 144 (1): 2–4.
https://doi.org/10.1182/blood.2024024713
Published: 2024
Journal Articles

The IL-7R antagonist lusvertikimab reduces leukemic burden in xenograft ALL via antibody-dependent cellular phagocytosis

Lennart Lenk, Irène Baccelli, Anna Laqua, Julia Heymann, Claas Reimer, Anna Dietterle, Dorothee Winterberg, Caroline Mary, Frédérique Corallo, Julien Taurelle, Emma Narbeburu, Stéphanie Neyton, Mylène Déramé, Sabrina Pengam, Fotini Vogiatzi, Beat Bornhauser, Jean-Pierre Bourquin, Simon Raffel, Vladyslava Dovhan, Thomas Schüler, Gabriele Escherich, Monique L. den Boer, Judith M. Boer, Wiebke Wessels, Matthias Peipp, Julia Alten, Željko Antić, Anke K. Bergmann, Martin Schrappe, Gunnar Cario, Monika Brüggemann, Nicolas Poirier, Denis M. Schewe
Journal: Blood
Blood (2024) 143 (26): 2735–2748.
https://doi.org/10.1182/blood.2023021088
Published: 2024
Includes: Supplemental data
Journal Articles

Tyrosine kinase inhibitor response of ABL-class acute lymphoblastic leukemia: the role of kinase type and SH3 domain

Inge van Outersterp, Sarah K. Tasian, Caitlin E. J. Reichert, Aurélie Boeree, Hester A. de Groot-Kruseman, Gabriele Escherich, Judith M. Boer, Monique L. den Boer
Journal: Blood
Blood (2024) 143 (21): 2178–2189.
https://doi.org/10.1182/blood.2023023120
Published: 2024
Includes: Supplemental data
Journal Articles

Novel Insights in TKI Resistance in BCR :: ABL1 -Positive B-Cell Acute Lymphoblastic Leukemia Beyond Kinase Domain Mutations

Inge Van Outersterp, Caitlin E.J. Reichert, Aurelie Boeree, Cesca Van De Ven, Brian Kruisinga, Hester A. de Groot-Kruseman, Gabriele Escherich, Anita W. Rijneveld, Judith M. Boer, Monique L. den Boer
Journal: Blood
Blood (2023) 142 (Supplement 1): 1615.
https://doi.org/10.1182/blood-2023-179704
Published: 2023
Journal Articles

Secondary Lesions and Sensitivity to Signaling Inhibitors of Pediatric iAMP21 B-Cell Precursor Acute Lymphoblastic Leukemia

Anna Ostergaard, Femke M. Hormann, Stijn Van Den Broek, Aurelie Boeree, Cesca Van De Ven, Gabriele Escherich, Edwin Sonneveld, Judith M. Boer, Monique L. Den Boer
Journal: Blood
Blood (2023) 142 (Supplement 1): 1613.
https://doi.org/10.1182/blood-2023-179719
Published: 2023
Journal Articles

Drug Response Profiling Informs Personalized Bridging to Cell Therapy for Patients with Relapsed/Refractory Acute Lymphoblastic Leukemia

Fabio D. Steffen, Andrej Lissat, Julia Alten, Cornelia Eckert, Nicole Bodmer, Bodil E. Thorhauge Als-Nielsen, Adriana Balduzzi, Barbara Buldini, Sarah Elitzur, Andras Kriston, Gergely Nyiri, Imre Västrik, Ferenc Kovacs, Francesco Ceppi, Lucie Sramkova, Larissa Schori, Arianna Arpagaus, Silvia Gutnik, Andishe Attarbaschi, Birgitte Klug Albertsen, Jeanette Greiner, Marc Ansari, Judith M. Boer, Elad Jacoby, Martin Stanulla, Uri Ilan, Peter M. Hoogerbrugge, Tim Lammens, Barbara De Moerloose, Petter Svenberg, Nicolas von der Weid, David O'Connor, Hélène Cavé, Franco Locatelli, Martin Schrappe, André Baruchel, Andreas Kulozik, Kjeld Schmiegelow, Gunnar Cario, Arend von Stackelberg, Peter Horvath, Beat Bornhauser, Jean-Pierre Bourquin
Journal: Blood
Blood (2023) 142 (Supplement 1): 4350.
https://doi.org/10.1182/blood-2023-179306
Published: 2023
Journal Articles

The Prognostic Effect of IKZF1 Deletions in ETV6 :: RUNX1 and High Hyperdiploid Childhood Acute Lymphoblastic Leukemia

Anna Østergaard, Amir Enshaei, Rob Pieters, Ajay Vora, Martin A. Horstmann, Gabriele Escherich, Bertil Johansson, Mats Heyman, Kjeld Schmiegelow, Peter M. Hoogerbrugge, Monique L. den Boer, Roland P. Kuiper, Anthony V. Moorman, Judith M. Boer, Frank N van Leeuwen
Journal: Blood
Blood (2022) 140 (Supplement 1): 3483–3485.
https://doi.org/10.1182/blood-2022-157431
Published: 2022
Journal Articles

Dutch ALL11 Study: Improved Outcome for Acute Lymphoblastic Leukemia By Prolonging Therapy for IKZF1 Deletion and Decreasing Therapy for ETV6::RUNX1, Down Syndrome and Prednisone Poor Responders

Rob Pieters, Hester A. De Groot-Kruseman, Femke Verwer, Merian van Overveld, Edwin Sonneveld, Marta Fiocco, Vincent H.J. van der Velden, Berna Beverloo, Marc Bierings, Valerie De Haas, Peter M. Hoogerbrugge, Inge M. Van Der Sluis, Wim J.E. Tissing, Margreet Veening, Judith M. Boer, Monique L. den Boer
Journal: Blood
Blood (2022) 140 (Supplement 1): 519–520.
https://doi.org/10.1182/blood-2022-165931
Published: 2022
Journal Articles

MicroRNA-497/195 is tumor suppressive and cooperates with CDKN2A/B in pediatric acute lymphoblastic leukemia

Elena Boldrin, Enrico Gaffo, Alexandra Niedermayer, Judith M. Boer, Martin Zimmermann, Dieter Weichenhan, Rainer Claus, Vera Münch, Qian Sun, Stefanie Enzenmüller, Felix Seyfried, Salih Demir, Julia Zinngrebe, Gunnar Cario, Martin Schrappe, Monique L. Den Boer, Christoph Plass, Klaus-Michael Debatin, Geertruij te Kronnie, Stefania Bortoluzzi, Lüder Hinrich Meyer
Journal: Blood
Blood (2021) 138 (20): 1953–1965.
https://doi.org/10.1182/blood.2020007591
Published: 2021
Includes: Supplemental data
Journal Articles

Minimal Residual Disease and Outcome Characteristics in Infant KMT2A-Germline Acute Lymphoblastic Leukemia Treated on the Interfant-06 Protocol

Janine Stutterheim, Paola De Lorenzo, Inge M. Van Der Sluis, Julia Alten, Philip Ancliffe, Andishe Attarbaschi, Luis Alberto Aversa, Judith M. Boer, Andrea Biondi, Benoit Brethon, Paulina Diaz, Giovanni Gazzaniga, Gabriele Escherich, Alina Ferster, Rishi S Kotecha, Birgitte Lausen, Alex WK Leung, Franco Locatelli, Lewis B. Silverman, Jan Stary, Tomasz Szczepanski, Vincent H.J. Van Der Velden, Ajay Vora, Jan Zuna, Martin Schrappe, Maria Grazia Valsecchi, Rob Pieters
Journal: Blood
Blood (2021) 138 (Supplement 1): 2383.
https://doi.org/10.1182/blood-2021-145058
Published: 2021
Journal Articles

SSBP2-CSF1R is a recurrent fusion in B-lineage acute lymphoblastic leukemia with diverse genetic presentation and variable outcome

Claire Schwab, Kathryn Roberts, Judith M. Boer, Gudrun Göhring, Doris Steinemann, Ajay Vora, Christine Macartney, Rachael Hough, Zoe Thorn, Richard Dillon, Gabriele Escherich, Giovanni Cazzaniga, Brigitte Schlegelberger, Mignon Loh, Monique L. den Boer, Anthony V. Moorman, Christine J. Harrison
Journal: Blood
Blood (2021) 137 (13): 1835–1838.
https://doi.org/10.1182/blood.2020008536
Published: 2021
Includes: Supplemental data
Journal Articles

NUTM1 -Rearranged Infant and Pediatric B Cell Precursor Acute Lymphoblastic Leukemia: A Good Prognostic Subtype Identified in a Collaborative International Study

Judith M. Boer, PhD, Maria Grazia Valsecchi, PhD, Femke M. Hormann, MSc, Zeljko Antic, MD, Marketa Zaliova, MD PhD, Claire Schwab, PhD, Giovanni Cazzaniga, PhD, Chloé Arfeuille, MD, Hélène Cavé, PharmD, PhD, Andishe Attarbaschi, MD, Sabine Strehl, PhD, Gabriele Escherich, MD, Toshihiko Imamura, MD PhD, Kentaro Ohki, MD PhD, Tanja A. Gruber, MD PhD, Rosemary Sutton, BSc MSc PhD, Agata Pastorczak, Tim Lammens, PhD, Frederic Lambert, MD, Chi Kong Li, MD, Enrique Carrillo de Santa Pau, PhD, Steve Hoffmann, MD PhD, Anja Möricke, MD, Christine J. Harrison, PhD FRCPath, Monique L. Den Boer, PhD, Paola De Lorenzo, Ronald W. Stam, PhD, Anke K. Bergmann, MD PhD, Rob Pieters, MDPhDMSc
Journal: Blood
Blood (2020) 136 (Supplement 1): 25–26.
https://doi.org/10.1182/blood-2020-139376
Published: 2020
Journal Articles

A validated novel continuous prognostic index to deliver stratified medicine in pediatric acute lymphoblastic leukemia

Clinical Trials & Observations
Amir Enshaei, David O’Connor, Jack Bartram, Jeremy Hancock, Christine J. Harrison, Rachael Hough, Sujith Samarasinghe, Monique L. den Boer, Judith M. Boer, Hester A. de Groot-Kruseman, Hanne V. Marquart, Ulrika Noren-Nystrom, Kjeld Schmiegelow, Claire Schwab, Martin A. Horstmann, Gabriele Escherich, Mats Heyman, Rob Pieters, Ajay Vora, John Moppett, Anthony V. Moorman
Journal: Blood
Blood (2020) 135 (17): 1438–1446.
https://doi.org/10.1182/blood.2019003191
Published: 2020
Includes: Supplemental data
Journal Articles

Acute Lymphoblastic Leukemia with Zinc-Finger Protein 384 (ZNF384)-Related Rearrangements: A Retrospective Analysis from the Ponte Di Legno Childhood ALL Working Group

Shinsuke Hirabayashi, Ellie Butler, Kentaro Ohki, MD PhD, Nobutaka Kiyokawa, MD PhD, Anke K. Bergmann, Judith M. Boer, PhD, Hélène Cavé, PharmD, PhD, Giovanni Cazzaniga, Allen Eng Juh Yeoh, Toshihiko Imamura, MD PhD, Hiroto Inaba, MD, Mignon L. Loh, MD, Ulrika Norén-Nyström, MD PhD, Agata Pastorczak, Lee-Yung Shih, MD, Marketa Zaliova, MD PhD, Oskar A Haas, Christine J. Harrison, PhD FRCPath, Anthony V. Moorman, Atsushi Manabe, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 652.
https://doi.org/10.1182/blood-2019-123236
Published: 2019
Journal Articles

Minimal Residual Disease and IKZF1 As Predictors of Relapse, and Increased Treatment Related Mortality in Down Syndrome Acute Lymphoblastic Leukemia: A Unique and Large International Matched Case-Control Study

Naomi Michels, BSc, Judith M. Boer, PhD, Marta Lopez-Yurda, PhD, Hester A. De Groot-Kruseman, PhD, Vincent van der Velden, PhD, Anthony V. Moorman, Amir Enshaei, PhD, Ajay Vora, Rosemary Sutton, BSc MSc PhD, Toby Trahair, PhD, Luciano Dalla-Pozza, MBBS FRACP, Rob Pieters, MDPhDMSc, Michel C Zwaan, MD PhD, Monique L. Den Boer, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 827.
https://doi.org/10.1182/blood-2019-124290
Published: 2019
Journal Articles

NUTM1 Is a Rare but Recurrent Fusion Gene Partner in B Cell Precursor Acute Lymphoblastic Leukemia Associated with Increased Expression of Genes on Cytoband 10p12.31

Femke M. Hormann, MSc, Alex Q. Hoogkamer, BSc, H. Berna Beverloo, PhD, Aurélie Boeree, BSc, Ronald W. Stam, PhD, Gabriele Escherich, Rob Pieters, MD PhD MSc, Monique L. Den Boer, PhD, Judith M. Boer, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2823.
https://doi.org/10.1182/blood-2018-99-112480
Published: 2018
Journal Articles

High PDGFRA Expression Does Not Serve As Effective Therapeutic Target in ERG -Deleted B-Cell Precursor Acute Lymphoblastic Leukemia

Isabel S. Jerchel, MSc, Judith M. Boer, PhD, Alex Q. Hoogkamer, BSc, H. Berna Beverloo, PhD, Rob Pieters, MD PhD, Monique L. den Boer, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1274.
https://doi.org/10.1182/blood.V130.Suppl_1.1274.1274
Published: 2017
Journal Articles

JAK2 Aberrations in Childhood B-Cell Precursor Acute Lymphoblastic Leukemia

Elisabeth M.P. Steeghs, MSc, Isabel S. Jerchel, MSc, Willemieke de Goffau-Nobel, MSc, Alex Q. Hoogkamer, BSc, Judith M. Boer, PhD, Aurélie Boeree, BSc, Cesca van de Ven, PhD, Marco J. Koudijs, PhD, Nicolle J.M. Besselink, BSc, Hester A. de Groot-Kruseman, PhD, C. Michel Zwaan, MD PhD, Martin A. Horstmann, MD, Rob Pieters, MD PhD, Monique L. Den Boer, PhD
Journal: Blood
Blood (2016) 128 (22): 583.
https://doi.org/10.1182/blood.V128.22.583.583
Published: 2016
Journal Articles

RAS Pathway Mutations As Predictive Biomarker for Treatment Adaptation in Pediatric B-Cell Precursor Acute Lymphoblastic Leukemia

Isabel S. Jerchel, MSc, Alex Q. Hoogkamer, BSc, Ingrid M. Ariës, PhD, Elisabeth M.P. Steeghs, MSc, Judith M. Boer, PhD, Nicolle J.M. Besselink, BSc, Aurélie Boeree, BSc, Cesca van de Ven, PhD, Hester A. de Groot-Kruseman, PhD, Valerie De Haas, MD PhD, Martin A. Horstmann, MD, Gabriele Escherich, MD, Ronald W. Stam, PhD, C. Michel Zwaan, MD PhD, Edwin Cuppen, PhD, Marco J. Koudijs, PhD, Rob Pieters, MD PhD, Monique L. Den Boer, MSc, PhD
Journal: Blood
Blood (2016) 128 (22): 4087.
https://doi.org/10.1182/blood.V128.22.4087.4087
Published: 2016