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Stefan Nierkens
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Journal Articles

Loss of p53 Impairs Death Receptor Expression and Confers Resistance to CD19-Directed CAR T-Cell Therapy in B-Cell Precursor Acute Lymphoblastic Leukemia

Willem P. J. Cox, Noel M. M. Dautzenberg, Linde Dekker, Tesa Klenovšek, Marliek van Hoesel, Gawin R. Stoll, Roland P. Kuiper, Laurens T. van der Meer, Friso G. J. Calkoen, Stefan Nierkens, Frank N. van Leeuwen
Journal: Blood
Blood (2023) 142 (Supplement 1): 598.
https://doi.org/10.1182/blood-2023-177911
Published: 2023
Journal Articles

Spatial Technologies Reveal the Immune Landscape of Pediatric Acute Myeloid Leukemia

Joost B. Koedijk, Inge Van Der Werf, Marijn A. Vermeulen, Alicia Perzolli, Marta F. Fiocco, Hester A. de Groot-Kruseman, Rubina Moeniralam, Kristina B. Christensen, Henrik Hasle, Stefan Nierkens, Mirjam E. Belderbos, Michel C. Zwaan, Olaf Heidenreich
Journal: Blood
Blood (2023) 142 (Supplement 1): 2959.
https://doi.org/10.1182/blood-2023-177932
Published: 2023
Journal Articles

Clonal Hematopoiesis Is Common in Long-Term Survivors of Pediatric Hematopoietic Cell Transplantation, Including Umbilical Cord Blood Transplantation

Konradin F. Müskens, Maaike G.J.M. van Bergen, Aniek O. de Graaf, Nienke Wieringa, Brigit M. te Pas, Anne P.J. de Pagter, Joëll E. Bense, Arjan C. Lankester, Leontien C.M. Kremer, Joop H. Jansen, Geert A. Huls, Stefan Nierkens, Caroline A. Lindemans, Mirjam E. Belderbos
Journal: Blood
Blood (2023) 142 (Supplement 1): 2697.
https://doi.org/10.1182/blood-2023-185985
Published: 2023
Journal Articles

Longitudinal Blood Count Analysis Reveals That Poor Graft Function after Pediatric Hematopoietic Cell Transplantation Is a Common Complication Associated with Poor Outcome

Konradin F. Müskens, Winny N.R. Collot-d'Escury, Rana Dandis, Saskia Haitjema, Caroline A. Lindemans, Stefan Nierkens, Mirjam E. Belderbos
Journal: Blood
Blood (2023) 142 (Supplement 1): 3534.
https://doi.org/10.1182/blood-2023-185750
Published: 2023
Journal Articles

High Risk of GvHD in Children Transplanted for Refractory Cytopenia of Childhood: Importance of Sufficient Exposure to Anti-Thymocyte Globulin

Eva Koopman-Coenen, Joyce Meesters-Ensing, Stefan Nierkens, Ireen J. Kal, Konradin F. Müskens, Birgitta Versluijs, Caroline A. Lindemans, Andrew C. Harris, Marc Bierings, Rick Admiraal, Mirjam E. Belderbos
Journal: Blood
Blood (2023) 142 (Supplement 1): 6997.
https://doi.org/10.1182/blood-2023-181662
Published: 2023
Journal Articles

Variable Immune Response Following BNT162b2 mRNA COVID-19 Vaccination in Pediatric Patients with Hematological Malignancies Under Treatment

Juliëtte Schmidt, Peter M. Hoogerbrugge, Caroline Lindemans, Stefan Nierkens, Robert S. Van Binnendijk, Louis J Bont, Wim J.E. Tissing
Journal: Blood
Blood (2022) 140 (Supplement 1): 6130–6131.
https://doi.org/10.1182/blood-2022-162258
Published: 2022
Journal Articles

Fludarabine Exposure Predicts Outcome after CD19 CAR T Cell Therapy in Children and Young Adults with Acute Leukemia; An Exploratory, Observational Study

Linde Dekker, Friso Calkoen, Yilin Jiang, Hilly Blok, Maike Spoon, Rick Admiraal, Peter Hoogerbrugge, Britta Julia Vormoor, Josef Vormoor, C. Michel Zwaan, Henk Visscher, Marc Bierings, Marieke Van Der Vlugt, Harm Van Tinteren, A. Laura Nijstad, Kim Van Der Elst, Alwin D. R. Huitema, Rob Pieters, Caroline Lindemans, Stefan Nierkens
Journal: Blood
Blood (2021) 138 (Supplement 1): 3871.
https://doi.org/10.1182/blood-2021-146450
Published: 2021
Journal Articles

CD4 + T-cell reconstitution predicts survival outcomes after acute graft-versus-host-disease: a dual-center validation

Clinical Trials & Observations
Coco de Koning, Susan Prockop, Ichelle van Roessel, Nancy Kernan, Elizabeth Klein, Jurgen Langenhorst, Celina Szanto, Mirjam Belderbos, Marc Bierings, Farid Boulad, Dorine Bresters, Maria Cancio, Kevin Curran, Wouter Kollen, Richard O’Reilly, Andromachi Scaradavou, Barbara Spitzer, Birgitta Versluijs, Alwin Huitema, Caroline Lindemans, Stefan Nierkens, Jaap Jan Boelens
Journal: Blood
Blood (2021) 137 (6): 848–855.
https://doi.org/10.1182/blood.2020007905
Published: 2021
Includes: Supplemental data
Journal Articles

B-Cell Precursor Acute Lymphoblastic Leukemia Instructs Mesenchymal Stromal Cells to Alter Interferon-Related Gene Expression and Cyto/Chemokine Secretion

Mandy W.E. Smeets, Femke Stalpers, BSc, Myrthe M.P. Vermeeren, BSc, Alex Q. Hoogkamer, BSc, Stefan Nierkens, PhD, Cesca Van De Ven, PhD, Monique L. Den Boer, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 4.
https://doi.org/10.1182/blood-2020-134649
Published: 2020
Journal Articles

Rapid and Robust CD4+ and CD8+ T-, NK-, B- and Monocyte Cell Reconstitution after Nicotinamide-Expanded Cord Blood Transplantation

Jaap Jan Boelens, MD PhD, Coco de Koning, Mitchell E. Horwitz, MD, Guillermo Sanz, Madan Jagasia, MD MS, John E. Wagner, MD, Patrick J. Stiff, MD, Rabi Hanna, MD, Daniela Cilloni, MD PhD, Stefan Nierkens, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2123.
https://doi.org/10.1182/blood-2018-99-116700
Published: 2018
Journal Articles

Cord Blood Regulatory T Cells for Prevention of Graft Versus Host Disease

Joshua Kellner, Stefan O. Ciurea, Amanda L. Olson, MD, Yago Nieto, MD PhD, Borje S Andersson, MDPhD, Joseph David Khoury, MD, Richard E. Champlin, MD, Stefan Nierkens, PhD, Jaap Jan Boelens, MD PhD, Bruce Blazar, MD, Simrit Parmar, MBBS
Journal: Blood
Blood (2017) 130 (Supplement 1): 3246.
https://doi.org/10.1182/blood.V130.Suppl_1.3246.3246
Published: 2017
Journal Articles

Excellent T-cell reconstitution and survival depend on low ATG exposure after pediatric cord blood transplantation

Clinical Trials & Observations
Rick Admiraal, Caroline A. Lindemans, Charlotte van Kesteren, Marc B. Bierings, A. Birgitta Versluijs, Stefan Nierkens, Jaap Jan Boelens
Journal: Blood
Blood (2016) 128 (23): 2734–2741.
https://doi.org/10.1182/blood-2016-06-721936
Published: 2016
Includes: Supplemental data
Journal Articles

Strategies before, during, and after hematopoietic cell transplantation to improve T-cell immune reconstitution

Coco de Koning, Stefan Nierkens, Jaap Jan Boelens
Journal: Blood
Blood (2016) 128 (23): 2607–2615.
https://doi.org/10.1182/blood-2016-06-724005
Published: 2016