1-20 of 51
Christoph Plass
Close
Save search
Follow your search
Access your saved searches in your account
Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles

The Proliferative History Index, Epicmit, Derived from Genome-Wide Epigenomic Profiling, Is a Key Driver of Clinical Survival in Splenic Marginal Zone Lymphoma

Helen Parker, Amatta Mirandari, Carolina Jaramillo-Oquendo, Marti Duran-Ferrer, Ben Stevens, Lara Buermann, Harindra Eranthi Amarasinghe, Jaya Thomas, Louise J. Carr, Shama Syeda, Methusha Sakthipakan, Marina Parry, Zadie Davies, Neil McIver-Brown, Aliki Xochelli, Sarah Ennis, Lydia Scarfo, Paolo Ghia, Christina H. Kalpadakis, Gerassimos Pangalis, Davide Rossi, Simon Wagner, Matthew Ahearne, Marc Seifert, Christoph Plass, Dieter Weichenhan, Eva Kimby, Lesley Ann Sutton, Richard Rosenquist, Francesco Forconi, Kostas Stamatopoulos, Marta Salido, Ana Ferrer, Catherine Thieblemont, David Graham Oscier, Renata Walewska, Matthew JJ Rose-Zerilli, Jane Gibson, Iñaki I. Martin Subero, Christopher C. Oakes, Dean J. Bryant, Jonathan C. Strefford
Journal: Blood
Blood (2023) 142 (Supplement 1): 4370.
https://doi.org/10.1182/blood-2023-174481
Published: 2023
Journal Articles

Multi-Omics Profiling of JMML HSPCs Reveals Onco-Fetal Reprogramming and Identifies Novel Prognostic Biomarkers and Therapeutic Targets in High-Risk JMML

Mark Hartmann, Ling Hai, Joschka Hey, Maximilian Schönung, Valentin Maurer, Jovana Rajak, Sina Staeble, Jens Langstein, Katharina Bauer, Mariam Hakobyan, Laura Jardine, Sheila Bohler, Dominik Vonficht, Abdul-Habib Maag, Dirk Lebrecht, Kathrin M. Bernt, Roland Roelz, Tobias Boch, Eleonora Khabirova, Pavlo Lutsik, Oliver Stegle, Simon Haas, Muzlifah Haniffa, Sam Behjati, Jan-Philipp Mallm, Christian Buske, Stefan Fröhling, Christoph Plass, Charlotte M. Niemeyer, Christian Flotho, Marc Jan Bonder, Miriam Erlacher, Matthias Schlesner, Daniel B. Lipka
Journal: Blood
Blood (2022) 140 (Supplement 1): 8729–8730.
https://doi.org/10.1182/blood-2022-162224
Published: 2022
Journal Articles

MicroRNA-497/195 is tumor suppressive and cooperates with CDKN2A/B in pediatric acute lymphoblastic leukemia

Elena Boldrin, Enrico Gaffo, Alexandra Niedermayer, Judith M. Boer, Martin Zimmermann, Dieter Weichenhan, Rainer Claus, Vera Münch, Qian Sun, Stefanie Enzenmüller, Felix Seyfried, Salih Demir, Julia Zinngrebe, Gunnar Cario, Martin Schrappe, Monique L. Den Boer, Christoph Plass, Klaus-Michael Debatin, Geertruij te Kronnie, Stefania Bortoluzzi, Lüder Hinrich Meyer
Journal: Blood
Blood (2021) 138 (20): 1953–1965.
https://doi.org/10.1182/blood.2020007591
Published: 2021
Includes: Supplemental data
Journal Articles

The age of the bone marrow microenvironment influences B-cell acute lymphoblastic leukemia progression via CXCR5-CXCL13

Costanza Zanetti, Rahul Kumar, Joscha Ender, Parimala S. Godavarthy, Mark Hartmann, Joschka Hey, Kersten Breuer, Eva S. Weissenberger, Valentina R. Minciacchi, Christina Karantanou, Zhaohui Gu, Kathryn G. Roberts, Markus Metzler, Wendy Stock, Charles G. Mullighan, Clara D. Bloomfield, Natalie Filmann, Katrin Bankov, Sylvia Hartmann, Robert P. Hasserjian, Antony F. Cousins, Christina Halsey, Christoph Plass, Daniel B. Lipka, Daniela S. Krause
Journal: Blood
Blood (2021) 138 (19): 1870–1884.
https://doi.org/10.1182/blood.2021011557
Published: 2021
Includes: Multimedia, Supplemental data
Journal Articles

Age-Related Changes in Human HSC Methylomes Affect Gene Regulatory Elements Critical to HSC Function and Reveal Novel HSC Aging Candidate Genes

Abdul-Habib Rahimi, Reka Toth, Dieter Weichenhan, Julia K. Herzig, Ekaterina Panina, Michael Heuser, Maximilian Schönung, Daniel B. Lipka, Pavlo Lutsik, Christoph Plass, Christian Buske
Journal: Blood
Blood (2021) 138 (Supplement 1): 2166.
https://doi.org/10.1182/blood-2021-148293
Published: 2021
Journal Articles

DNA Methylation As a Biomarker of Outcome in JMML: An International Effort Towards Clinical Implementation

Julia Meyer, PhD, Maximillian Schönung, Christian Flotho, MD PhD, Adam B. Olshen, PhD, Mark Hartmann, PhD, Christoph Plass, PhD, Yusuke Okuno, MD PhD, Yoshiyuki Takahashi, MD PhD, Norihiro Murakami, MD PhD, Manabu Wakamatsu, MD, Mignon L. Loh, MD, Charlotte M. Niemeyer, MD, Hideki Muramatsu, MD PhD, Daniel B. Lipka, MD, Elliot Stieglitz, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1693.
https://doi.org/10.1182/blood-2019-131279
Published: 2019
Journal Articles

Deconvolution of Hematopoietic Commitment Decisions By Genome-Wide Analysis of Progressive DNA Methylation Changes

Sina Staeble, MSc, Stephen Kraemer, MSc, Jens Langstein, MSc, Ruzhica Bogeska, PhD, Mark Hartmann, PhD, Maximilian Schoenung, MSc, Melinda Czeh, PhD, Julia Knoch, Natasha Anstee, PhD, Simon Haas, PhD, Abdelrahman Mahmoud, MSc, Julius Graesel, MSc, Daniel Huebschmann, MD PhD, Lars Feuerbach, PhD, Weichenhan Dieter, PhD, Benedikt Brors, PhD, Karsten Rippe, PhD, Jan-Philipp Mallm, PhD, Frank Rosenbauer, PhD, Christoph Plass, PhD, Matthias Schlesner, PhD, Michael D. Milsom, PhD, Daniel B. Lipka, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1179.
https://doi.org/10.1182/blood-2019-124429
Published: 2019
Journal Articles

DNA Methylation Subgroups in Juvenile Myelomonocytic Leukemia: An International Collaborative Analysis and Development of a Common Diagnostic Platform

Maximilian Schoenung, Elliot Stieglitz, Hideki Muramatsu, MD PhD, Norihiro Murakami, MD, Mark Hartmann, Manuel Wiesenfarth, Yusuke Okuno, MD PhD, Adam B. Olshen, PhD, Christoph Plass, Mignon L. Loh, MD, Charlotte Niemeyer, MD, Christian Flotho, Daniel B. Lipka
Journal: Blood
Blood (2018) 132 (Supplement 1): 3093.
https://doi.org/10.1182/blood-2018-99-114918
Published: 2018
Journal Articles

Modeling of the Epigenome of the Cell-of-Origin Identifies Cancer-Specific DNA Methylation Patterns in CLL

Justyna Anna Wierzbinska, Reka Toth, Naveed Ishaque, Jan-Phillip Mallm, Karsten Rippe, Daniel Mertens, Thomas Hielscher, Thorsten Zenz, MD, Marc Seifert, Ralf Küppers, Yassen Assenov, Stephan Stilgenbauer, John C. Byrd, MD, Christopher C. Oakes, Daniel B. Lipka, Christoph Plass
Journal: Blood
Blood (2018) 132 (Supplement 1): 3885.
https://doi.org/10.1182/blood-2018-99-115941
Published: 2018
Journal Articles

Recurrent Mutations in EGR2 Direct Specific Epigenetic Reconfiguration in Chronic Lymphocytic Leukemia

Christoph Weigel, PhD, Yassen Assenov, Charles Imbusch, Qi Wang, Renée Beekman, Brian Giacopelli, BS, Yue-zhong Wu, MSc, David Brocks, Weichenhan Dieter, Popanda Odilia, Peter Schmezer, Benedikt Brors, Daniel Mertens, Karsten Rippe, Laura Z. Rassenti, PhD, Thomas J. Kipps, MD PhD, Jennifer A. Woyach, MD, James S. Blachly, MD, Elias Campo, Thorsten Zenz, MD, John C. Byrd, MD, José I. Martin-Subero, PhD, Christoph Plass, Christopher C. Oakes
Journal: Blood
Blood (2018) 132 (Supplement 1): 650.
https://doi.org/10.1182/blood-2018-99-119070
Published: 2018
Journal Articles

5-Azacytidine Is Effective for Targeting Leukemia-Initiating Cells in Juvenile Myelomonocytic Leukemia

Christopher Felix Krombholz, PhD, Lorena Gallego Villar, PhD, Pritam Kumar Panda, MSc, MS, BSc, Sushree Sangita Sahoo, MSc, Marcin W. Wlodarski, MD PhD, Daniel B. Lipka, Christoph Plass, Charlotte Niemeyer, MD, Miriam Erlacher, MD PhD, Christian Flotho
Journal: Blood
Blood (2018) 132 (Supplement 1): 4342.
https://doi.org/10.1182/blood-2018-99-116594
Published: 2018
Journal Articles

Cooperative Effects of a Dnmt Inhibitor and All- Trans Retinoic Acid in an AML Cell Line Model Lacking PML-Rara

Ruth Meier, Gabriele Greve, Christoph Niemöller, Heiko Becker, Tobias Ma, Ralitsa Langova, Björn Grüning, Lars Feuerbach, Daniel B. Lipka, Justus Duyster, Prof., Benedikt Brors, Christoph Plass, Michael Lübbert
Journal: Blood
Blood (2018) 132 (Supplement 1): 1359.
https://doi.org/10.1182/blood-2018-99-113450
Published: 2018
Journal Articles

Malignant NK Cells from EBV(+) Human Extranodal NK/T Cell Lymphoma Exhibit Features of a Distinct NK Cell Developmental Subset Found in Mucosal Associated Lymphoid Tissue

Anjali Mishra, PhD, Bethany L Mundy-Bosse, PhD, Karen A Young, Christoph Weigel, PhD, Emily Smith, Ahmed Elshafa, Youssef Youssef, Kathleen McConnell, Christoph Plass, PhD, Jonathan E Brammer, MD, Robert A Baiocchi, MD PhD, Michael A. Caligiuri, MD, Pierluigi Porcu, MD, Aharon G. Freud, MD PhD, Christopher C. Oakes, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1451.
https://doi.org/10.1182/blood.V130.Suppl_1.1451.1451
Published: 2017
Journal Articles

Epigenetic Drug Treatment Globally Induces Cryptic Transcription Start Sites Encoded in Long Terminal Repeats

Michael Daskalakis, David Brocks, Christopher Schmidt, Daofeng Li, Jing Li, Hyo S. Jang, Bo Zhang, Daniel B Lipka, Johanna Schott, Holger Bierhoff, Yassen Assenov, Monika Helf, Alzbeta Ressnerova, Anders Lindroth, Simon Haas, Marieke A. G. Essers, Charles D. Imbusch, Benedikt Brors, Ina Oehme, Olaf Witt, Michael Lübbert, MD, Georg Stoecklin, Clarissa Gerhäuser, Christopher C Oakes, PhD, Ting Wang, Christoph Plass
Journal: Blood
Blood (2016) 128 (22): 3931.
https://doi.org/10.1182/blood.V128.22.3931.3931
Published: 2016
Journal Articles

Surface IgM expression and function are associated with clinical behavior, genetic abnormalities, and DNA methylation in CLL

Clinical Trials & Observations
Annalisa D’Avola, Samantha Drennan, Ian Tracy, Isla Henderson, Laura Chiecchio, Marta Larrayoz, Matthew Rose-Zerilli, Jonathan Strefford, Christoph Plass, Peter W. Johnson, Andrew J. Steele, Graham Packham, Freda K. Stevenson, Christopher C. Oakes, Francesco Forconi
Journal: Blood
Blood (2016) 128 (6): 816–826.
https://doi.org/10.1182/blood-2016-03-707786
Published: 2016
Includes: Supplemental data
Journal Articles

Progressive Epigenetic Programming during B Cell Maturation Is Reflected in a Continuum of Epigenetic Disease Phenotypes in Chronic Lymphocytic Leukemia

Christopher C. Oakes, PhD, Marc Seifert, Yassen Assenov, Lei Gu, Martina Przekopowitz, Amy S. Ruppert, MAS, Qi Wang, Charles Imbusch, Andrius Serva, Sandra Koser, David Brocks, Daniel B Lipka, Olga Bogatyrova, Benedikt Brors, Dieter Weichenhan, Laura Z. Rassenti, PhD, Thomas J. Kipps, MD PhD, Daniel Mertens, PhD, Marc Zapatka, Peter Lichter, Hartmut Döhner, MD, Ralf Kueppers, Thorsten Zenz, Stephan Stilgenbauer, MD, John C Byrd, MD, Christoph Plass, PhD
Journal: Blood
Blood (2015) 126 (23): 2436.
https://doi.org/10.1182/blood.V126.23.2436.2436
Published: 2015
Journal Articles

IL-10 Production By CLL Cells Is Enhanced in the Anergic IGHV Mutated Subset and Associates with Reduced DNA Methylation of the IL-10 Locus

Samantha Drennan, PhD, Annalisa D'Avola, MSc, Yifang Gao, PhD, Eleni Chrysostomou, MSc, Andrew J Steele, PhD, Thorsten Zenz, MD, Christoph Plass, PhD, Peter W Johnson, MD, Anthony P Williams, PhD FRCPath, Graham Packham, PhD, Freda K Stevenson, DPhil, Christopher C. Oakes, PhD, Francesco Forconi, MD DM, PhD FRCPath
Journal: Blood
Blood (2015) 126 (23): 2917.
https://doi.org/10.1182/blood.V126.23.2917.2917
Published: 2015
Journal Articles

Epigenetic Changes Accompany Disordered Hemoglobin Regulation in Juvenile Myelomonocytic Leukemia

Silvia Fluhr, Christopher Felix Krombholz, Angelina Meier, Christoph Plass, Charlotte Niemeyer, Christian Flotho
Journal: Blood
Blood (2015) 126 (23): 438.
https://doi.org/10.1182/blood.V126.23.438.438
Published: 2015
Journal Articles

5-Azacytidine Reduces Leukemic Burden in a Xenograft Model of Juvenile Myelomonocytic Leukemia

Christopher Felix Krombholz, Angelina Meier, Konrad Aumann, Silvia Fluhr, Matthias Kollek, Daniel B Lipka, Christoph Plass, Tania Witte, Charlotte Niemeyer, Miriam Erlacher, Christian Flotho
Journal: Blood
Blood (2015) 126 (23): 1655.
https://doi.org/10.1182/blood.V126.23.1655.1655
Published: 2015
Journal Articles

NFATc1 Is Transcriptionally Activated in Chronic Lymphocytic Leukemia (CLL) By Promotor DNA-Hypomethylation Which Correlates with in-Vitro Vulnerability to Calcineurin Inhibitors

Christine Wolf, Katharina Filarsky, Angela Garding, PhD, Rainer Claus, MD, Christopher C Oakes, PhD, Irina Idler, PhD, Christoph Plass, PhD, Peter Lichter, PhD, Hartmut Doehner, MD, Stephan Stilgenbauer, MD, Daniel Mertens, PhD
Journal: Blood
Blood (2014) 124 (21): 1941.
https://doi.org/10.1182/blood.V124.21.1941.1941
Published: 2014