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Journal Articles

Antigen Receptor Gene Repertoire Profiling in Kidney Transplant Recipients Post-Sars-Cov-2 Vaccination

Antonios Mingos, Nikolaos Pechlivanis, Georgios Karakatsoulis, Glykeria Gkoliou, Nikolaos Vastarouchas, Smaragdi Marinaki, Paraskevi Tsoutsoura, Myrto Papamentzelopoulou, Vassiliki Pitiriga, Mina Psichogiou, Angelos Hatzakis, Kostas Stamatopoulos, Elisavet Vlachonikola, Anastasia Chatzidimitriou
Journal: Blood
Blood (2023) 142 (Supplement 1): 5372.
https://doi.org/10.1182/blood-2023-188494
Published: 2023
Journal Articles

The Deubiquitinase CYLD Acts As an Oncogene in a Cellular Model of Chronic Lymphocytic Leukemia

Marina Gerousi, Georgios Gavriilidis, Sofoklis Keisaris, Artemis Kourouni, Aspasia Orfanou, Anastasia Iatrou, Athanasios Pseftogkas, George Mosialos, Eleni Theodosiou, Anastasia Chatzidimitriou, Fotis Psomopoulos, Paolo Ghia, Kostas Stamatopoulos, Konstantinos Xanthopoulos
Journal: Blood
Blood (2023) 142 (Supplement 1): 3265.
https://doi.org/10.1182/blood-2023-188983
Published: 2023
Journal Articles

Patients with Chronic Lymphocytic Leukemia Carrying t(14;19) Display a Distinctive Transcriptomic Profile and Adverse Outcome, Which Might be Overcome Continuous Therapy with BTK Inhibitors. an Italian Campus CLL and Eric Study

Andrea Visentin, Enrico Gaffo, Moritz Furstenau, Jennifer A. Woyach, Panagiotis Baliakas, Kerry A Rogers, Cecelia Miller, Claudia Haferlach, Karla Plevova, David Graham Oscier, Zadie Davis, Florence Nguyen Khac, Eleonora Roncaglia, Gian Matteo Rigolin, Anastasia Athanasiadou, Fanny Baran-Marszak, Alberto Valiente, Maria Jose Terol, Pau Abrisqueta, Blanca Espinet, Anna Puiggros, Annalisa Martines, Laura Bonaldi, Francesca Romana Mauro, Lydia Scarfo, Thomas Chatzikonstantinou, Eugen Tausch, Karl Anton Kreuzer, Arnon P. Kater, Francesc Bosch, Michael Doubek, Panayiotis Panayiotidis, Olga Kalashnikova, Federica Frezzato, Monica Facco, Valeria Ruocco, Alessia Buratin, Silvia Orsi, Alessandro Cellini, Francesco Angotzi, Chiara Adele Cavarretta, Ivan Zatta, Andrea Serafin, Robin Foa, Barbara F. Eichhorst, Antonio Cuneo, Kostas Stamatopoulos, Paolo Ghia, Stefania Bortoluzzi, Livio Trentin
Journal: Blood
Blood (2023) 142 (Supplement 1): 3275.
https://doi.org/10.1182/blood-2023-174569
Published: 2023
Journal Articles

Laboratories Can Reliably Detect Clinically Relevant Variants in the TP53 Gene below 10 % Allelic Frequency: A Multicenter Study of ERIC, the European Research Initiative on CLL

Sarka Pavlova, Jitka Malcikova, Lenka Radova, Silvia Bonfiglio, Jack B. Cowland, Christian Brieghel, Mette Klarskov Andersen, Maria Karypidou, Bella V Biderman, Michael Doubek, Gregory Lazarian, Inmaculada Rapado, Matthijs Vynck, Naomi Porret, Martin Andres, Dina Rosenberg, Dvora Sahar, Carolina Martinez-Laperche, Ismael Buño Borde, Andrew Hindley, Julio Bravo Sánchez, José García-Marco, Alicia Serrano, Blanca Ferrer Lores, Concepción Fernández-Rodriguez, Beatriz Bellosillo, Stephan Stilgenbauer, Eugen Tausch, Hero Nikdin, Fiona Quinn, Emer Atkinson, Lisette Van De Corput, Cafer Yildiz, Cristina Bilbao, Yanira Florido, Christian Thiede, Caroline Schuster, Anastazja Stoj, Sylwia Czekalska, Anastasia Chatzidimitriou, Stamatia Laidou, Audrey Bidet, Charles Dussiau, Friedel Nollet, Giovanna Piras, Tereza Borosova, Terezia Kurucova, Maria Monne, Svetlana Smirnova, Evgeny Nikitin, Ivan Sloma, Marie-Helene Delfau, Laetitia Largeaud, Loic Ysebaert, Peter J. M. Valk, Amy Christian, Renata Walewska, Marta Sebastião, Maria Gomes da Silva, Piero Galieni, Mario Angelini, Davide Rossi, Valeria Spina, Sónia Matos, Vânia Martins, David Donaldson, Tomasz Stoklosa, Monika Pepek, Panagiotis Baliakas, Rafa Andreu, Irene Luna, Tiina Kahre, Ülle Murumets, Sophie Laird, Daniel Ward, Miguel Alcoceba, Ana Balanzategui, Lydia Scarfo, Francesca Gandini, Ettore Zapparoli, Adoracion Blanco, Pau Abrisqueta Costa, Ana E. Rodriguez, Maria Rocio Benito Sanchez, Frédéric Davi, Clothilde Bravetti, Paula Gameiro, Joaquin Martinez-Lopez, Barbara Tazon, Fanny Baran-Marszak, Zadie Davies, Mark Caterwood, Andrey B Sudarikov, Richard Rosenquist, Carsten Utoft Niemann, Kostas Stamatopoulos, Paolo Ghia, Sarka Pospisilova
Journal: Blood
Blood (2023) 142 (Supplement 1): 200.
https://doi.org/10.1182/blood-2023-173235
Published: 2023
Journal Articles

Evidence of Defective Cell-Autonomous Signalling By B Cell Receptors in CLL Stereotyped Subset #1

Claudia Minici, Paolo G. Cocomazzi, Can Akpınaroğlu, Anastasia Iatrou, Maria Gounari, Michela Frenquelli, Lydia Scarfo, Christian Buske, Andreas Agathangelidis, Hassan Jumaa, Palash Maity, Paolo Ghia, Kostas Stamatopoulos, Massimo Degano
Journal: Blood
Blood (2023) 142 (Supplement 1): 3255.
https://doi.org/10.1182/blood-2023-181702
Published: 2023
Journal Articles

The Proliferative History Index, Epicmit, Derived from Genome-Wide Epigenomic Profiling, Is a Key Driver of Clinical Survival in Splenic Marginal Zone Lymphoma

Helen Parker, Amatta Mirandari, Carolina Jaramillo-Oquendo, Marti Duran-Ferrer, Ben Stevens, Lara Buermann, Harindra Eranthi Amarasinghe, Jaya Thomas, Louise J. Carr, Shama Syeda, Methusha Sakthipakan, Marina Parry, Zadie Davies, Neil McIver-Brown, Aliki Xochelli, Sarah Ennis, Lydia Scarfo, Paolo Ghia, Christina H. Kalpadakis, Gerassimos Pangalis, Davide Rossi, Simon Wagner, Matthew Ahearne, Marc Seifert, Christoph Plass, Dieter Weichenhan, Eva Kimby, Lesley Ann Sutton, Richard Rosenquist, Francesco Forconi, Kostas Stamatopoulos, Marta Salido, Ana Ferrer, Catherine Thieblemont, David Graham Oscier, Renata Walewska, Matthew JJ Rose-Zerilli, Jane Gibson, Iñaki I. Martin Subero, Christopher C. Oakes, Dean J. Bryant, Jonathan C. Strefford
Journal: Blood
Blood (2023) 142 (Supplement 1): 4370.
https://doi.org/10.1182/blood-2023-174481
Published: 2023
Journal Articles

Distinct T Cell Receptor Gene Repertoires and T Cell Subset Distribution in Peripheral Blood and Bone Marrow of Patients with Multiple Myeloma

Glykeria Gkoliou, Nikolaos Pechlivanis, Sofia Chatzileontiadou, Chara Xydopoulou, Christina Frouzaki, Georgios Karakatsoulis, Elisavet Vlachonikola, Marina Gerousi, Fotis Psomopoulos, Maria Papaioannou, Katerina Chlichlia, Kostas Stamatopoulos, Evdoxia Hatjiharissi, Anastasia Chatzidimitriou
Journal: Blood
Blood (2023) 142 (Supplement 1): 4677.
https://doi.org/10.1182/blood-2023-185872
Published: 2023
Journal Articles

Precision Targeting of the Malignant Clone in Diffuse Large B Cell Lymphoma Using Chimeric Antigen Receptor T Cells Against the Clonotypic IGHV4-34 B Cell Receptor

Ivan J Cohen, Audrey C Bochi-Layec, Ki Hyun Kim, Scott Jenks, Ositadimma Ugwuanyi, Guido Ghilardi, Giulia Gabrielli, Jaryse Harris, Li-Ping Wang, Yunlin Zhang, Raymone Pajarillo, Elisavet Vlachonikola, Patrizia Porazzi, Ignacio Sanz, Paolo Ghia, Kostas Stamatopoulos, Stephen J Schuster, Marco Ruella
Journal: Blood
Blood (2023) 142 (Supplement 1): 1020.
https://doi.org/10.1182/blood-2023-187618
Published: 2023
Journal Articles

DNA Methylation-Based Classification of Hairy Cell Leukemia and Splenic B Cell Lymphoma

Kyoko Yamaguchi, Salma Abdelbaky, Evgeny Arons, Matthew Cross, Yue-Zhong Wu, Christoph Weigel, Mirela Iulia Anghelina, Helen Parker, Artur Kibler, Marta Salido, Constance Regina Baer, Manja Meggendorfer, Benjamin Durham, Omar Abdel-Wahab, Seema A Bhat, Gerard Lozanski, Kerry A Rogers, Yonghong Wang, Paul S. Meltzer, Sunil Iyengar, Sascha Dietrich, Thorsten Zenz, James S. Blachly, Aurelie Verney, Lucile Baseggio, Alexandra Traverse-Glehen, Marc Seifert, Ralf Kuppers, Richard Burack, Clive S Zent, Versha Banerji, James B. Johnston, David Graham Oscier, Renata Walewska, Kostas Stamatopoulos, Torsten Haferlach, Ana Ferrer, Catherine Thieblemont, Francesco Forconi, Robert Kreitman, Michael R. Grever, Jonathan C. Strefford, Piers Blombery, Christopher C. Oakes
Journal: Blood
Blood (2023) 142 (Supplement 1): 174.
https://doi.org/10.1182/blood-2023-189835
Published: 2023
Journal Articles

DeepSurf2.0: A Deep Learning Approach for Predicting Interactions of B Cell Receptors with Antigens

Angelos-Michael Papadopoulos, Anastasia Iatrou, Apostolos Axenopoulos, Andreas Agathangelidis, Kostas Stamatopoulos, Petros Daras
Journal: Blood
Blood (2023) 142 (Supplement 1): 3930.
https://doi.org/10.1182/blood-2023-188537
Published: 2023
Journal Articles

Chromatin activation profiling of stereotyped chronic lymphocytic leukemias reveals a subset 8–specific signature

Brief Report
Maria Tsagiopoulou, Vicente Chapaprieta, Nuria Russiñol, Beatriz García-Torre, Nikolaos Pechlivanis, Ferran Nadeu, Nikos Papakonstantinou, Niki Stavroyianni, Anastasia Chatzidimitriou, Fotis Psomopoulos, Elías Campo, Kostas Stamatopoulos, José Ignacio Martín-Subero
Journal: Blood
Blood (2023) 141 (24): 2955–2960.
https://doi.org/10.1182/blood.2022016587
Published: 2023
Includes: Supplemental data
Journal Articles

A Comprehensive DNA Methylome Analysis of Stereotyped and Non-Stereotyped CLL Reveals an Epigenetic Signature with Strong Clinical Impact Encompassing IGHV Status, Stereotypes and IGLV3-21 R110

Martí Duran-Ferrer, Larry Mansouri, Ferran Nadeu, Guillem Clot, Sujata Bhoi, Lesley Ann Sutton, Panagiotis Baliakas, Sara Ek, Venera Kuci Emruli, Karla Plevova, Zadie Davis, Hanna Goransson-Kultima, Anders Isaksson, Karin E. Smedby, Gianluca Gaidano, Anton W. Langerak, Frederic Davi, Davide Rossi, David Oscier, Sarka Pospisilova, Maria Karypidou, Andreas Agathangelidis, Wolfgang Huber, Junyan Lu, Thorsten Zenz, Julio Delgado, Armando Lopez-Guillermo, Paolo Ghia, Elías Campo, Kostas Stamatopoulos, Richard Rosenquist, José I. Martín-Subero
Journal: Blood
Blood (2022) 140 (Supplement 1): 1800–1802.
https://doi.org/10.1182/blood-2022-165181
Published: 2022
Journal Articles

Molecular and Functional Profiling of Microenvironmental Interactions in Splenic Marginal Zone Lymphoma

Marina Gerousi, Anastasia Iatrou, Antonios Mingos, Nikolaos Pechlivanis, Stavroula Ntoufa, Maria Gounari, Nikos Papakonstantinou, Georgios Karakatsoulis, Eleni Kotroni, Ioannis Sarrigeorgiou, Zadie Davis, Peggy Lymberi, David Oscier, Ioanna Sakellari, Alexandra Traverse-Glehen, Niki Stavroyianni, Fotis Psomopoulos, Marta Muzio, Paolo Ghia, Anastasia Chatzidimitriou, Kostas Stamatopoulos
Journal: Blood
Blood (2022) 140 (Supplement 1): 9294–9295.
https://doi.org/10.1182/blood-2022-168728
Published: 2022
Journal Articles

High Incidence of Clonal Hematopoiesis in Transfusion-Dependent Thalassemia Patients

Elena E. Solomou, Polyxeni Delaporta, Laidou Stamatia, Efthymia-Vasilina Katsika, Marianna Chatzieleftheriou, Konstantina Toutoudaki, Stavros Glentis, Kostas Stamatopoulos, Anastasia Chatzidimitriou, Antonis Kattamis
Journal: Blood
Blood (2022) 140 (Supplement 1): 8213–8214.
https://doi.org/10.1182/blood-2022-159246
Published: 2022
Journal Articles

An Immunogenetic Imprint of Ongoing Antigen Interactions in Hairy Cell Leukemia Expressing IGHV4-34 Receptors

Electra Sofou, Maria Karypidou, Laura Zaragoza-Infante, Nikolaos Pechlivanis, Fotis Psomopoulos, Elisavet Georgiou, Evgeny Arons, Robert J. Kreitman, Anastasia Chatzidimitriou, Kostas Stamatopoulos
Journal: Blood
Blood (2022) 140 (Supplement 1): 6399–6400.
https://doi.org/10.1182/blood-2022-168554
Published: 2022
Journal Articles

Longitudinal Profiling of the T Cell Compartment in Patients with Chronic Lymphocytic Leukemia Treated with Venetoclax

Elisavet Vlachonikola, Electra Sofou, Marina Gerousi, Efthimia Katsika, Nikolaos Pechlivanis, Georgios Karakatsoulis, Maria Dimou, Thomas Chatzikonstantinou, Michail Iskas, Panagiotis Panagiotidis, Ioanna Sakellari, Niki Stavroyianni, Kostas Stamatopoulos, Anastasia Chatzidimitriou
Journal: Blood
Blood (2022) 140 (Supplement 1): 9891–9892.
https://doi.org/10.1182/blood-2022-162173
Published: 2022
Journal Articles

Thrombotic and Bleeding Complications in Patients with Chronic Lymphocytic Leukemia and Severe COVID-19: A Study of Eric, the European Research Initiative on CLL

Darko Antic, Natasa Milic, Thomas Chatzikonstantinou, Lydia Scarfò, Vladimir Otasevic, Nina Rajovic, David Allsup, Alejandro Alonso Cabrero, Martin Andres, Monica Baile Gonzales, Antonella Capasso, Rosa Collado, Raul Cordoba, Carolina Cuéllar-García, Juan Gonzalo Correa, Lorenzo De Paoli, Maria Rosaria De Paolis, Giovanni Del Poeta, Maria Dimou, Michael Doubek, Maria Efstathopoulou, Shaimaa El-Ashwah, Alicia Enrico, Blanca Espinet, Lucia Farina, Angela Ferrari, Myriam Foglietta, Alberto Lopez-Garcia, Jose A. Garcia-Marco, Rocío García-Serra, Massimo Gentile, Eva Gimeno, Maria Gomes da Silva, Odit Gutwein, Yervand Hakobyan, Yair Herishanu, José Ángel Hernández-Rivas, Tobias Herold, Gilad Itchaki, Ozren Jaksic, Ann Janssens, Оlga B. Kalashnikova, Elżbieta Kalicińska, Arnon P. Kater, Sabina Kersting, Maya Koren-Michowitz, Jorge Labrador Gomez, Deepesh Lad, Luca Laurenti, Alberto Fresa, Mark-David Levin, Carlota Mayor Bastida, Lara Malerba, Roberto Marasca, Monia Marchetti, Juan Marquet, Biljana Mihaljevic, Ivana Milosevic, Fatima Mirás, Marta Morawska, Marina Motta, Talha Munir, Roberta Murru, Raquel Nunes, Jacopo Olivieri, Miguel Arturo Pavlovsky, Inga S. Piskunova, Viola Maria Popov, Francesca Maria Quaglia, Giulia Quaresmini, Gianluigi Reda, Gian Matteo Rigolin, Amit Shrestha, Martin Šimkovič, Svetlana Smirnova, Martin Špaček, Paolo Sportoletti, Oana Stanca, Niki Stavroyianni, Doreen Te Raa, Kristina Tomic, Sanne Tonino, Livio Trentin, Ellen Van Der Spek, Michel van Gelder, Marzia Varettoni, Andrea Visentin, Candida Vitale, Vojin Vukovic, Ewa Wasik-Szczepanek, Tomasz Wróbel, Lucrecia Yanez San Segundo, Mohamed A Yassin, Marta Coscia, Alessandro Rambaldi, Emili Montserrat, Robin Foà, Antonio Cuneo, Marc Carrier, Paolo Ghia, Kostas Stamatopoulos
Journal: Blood
Blood (2022) 140 (Supplement 1): 2772–2775.
https://doi.org/10.1182/blood-2022-169909
Published: 2022
Journal Articles

Autonomous BCR Signaling and Genetic Aberrations in CLL-Phenotype Monoclonal B Lymphocytosis in Siblings of CLL Patients

Julieta H. Sepulveda Yanez, Edwin Quinten, Marvyn T. Koning, Janneke A. Eken, Dietmar Pfeifer, Ruben A.L. De Groen, Diego Alvarez Saravia, Andreas Agathangelidis, Cornelis A.M. van Bergen, Kostas Stamatopoulos, Joost S.P. Vermaat, Katja Zirlik, Marcelo Navarrete, Hassan Jumaa, Hendrik Veelken
Journal: Blood
Blood (2022) 140 (Supplement 1): 1526–1527.
https://doi.org/10.1182/blood-2022-169429
Published: 2022
Journal Articles

T Cell Epitope Prediction within the Clonotypic Immunoglobulin Heavy and Light Chains in Patients with Multiple Myeloma

Glykeria Gkoliou, Nikos Pechlivanis, Sofia Chatzileontiadou, Chara Xydopoulou, Christina Frouzaki, Georgios Karakatsoulis, Elisavet Vlachonikola, Marina Gerousi, Fotis Psomopoulos, Maria Papaioannou, Katerina Chlichlia, Kostas Stamatopoulos, Evdoxia Hatjiharissi, Anastasia Chatzidimitriou
Journal: Blood
Blood (2022) 140 (Supplement 1): 12444–12445.
https://doi.org/10.1182/blood-2022-159992
Published: 2022
Journal Articles

Differences in Clinical Course and Management of Sars-CoV2 Infection in Patients with Chronic Lymphocytic Leukemia between the Sequential Pandemic Phases: An Eric Study

Andrea Visentin, Lydia Scarfò, Thomas Chatzikonstantinou, Anargyros Kapetanakis, Christos Demosthenous, Georgios Karakatsoulis, Martin Andres, Darko Antic, David Allsup, Mónica Baile, Dominique Bron, Antonella Capasso, Mark Catherwood, Rosa Collado, Raul Cordoba, Carolina Cuéllar-García, Julio Delgado, Maria Dimou, Michael Doubek, Lorenzo De Paoli, Maria Rosaria De Paolis, Giovanni Del Poeta, Maria Efstathopoulou, El-Ashwah Shimaa, Alicia Enrico, Lucia Farina, Angela Ferrari, Myriam Foglietta, Moritz Furstenau, Jose A. Garcia-Marco, Massimo Gentile, Eva Gimeno, Gomes da Silva Maria, Odit Gutwein, Yervand Hakobyan, Yair Herishanu, jose Angel Hernandez, Tobias Herold, Sunil Iyengar, Gilad Itchaki, Ozren Jaksic, Ann Janssens, Olga Kalashnikova, Elzbieta Kalicinska, Arnon P. Kater, Sabina Kersting, Jorge Labrador, Deepesh Lad, Luca Laurenti, Mark-David Levin, Enrico Lista, Lara Malerba, Roberto Marasca, Monia Marchetti, Juan Marquet Palomanes, Mattias Mattsson, Francesca Romana Mauro, Carlota Mayor-Bastida, Marta Morawska, Marina Motta, Talha Munir, Roberta Murru, Ivana Milosevic, Fatima Miras Calvo, Carsten Utoft Niemann, Jacopo Olivieri, Lorella Orsucci, Maria Papaioannou, Miguel Arturo Pavlovsky, Inga S. Piskunova, Barbara Pocali, Viola Maria Popov, Francesca Maria Quaglia, Giulia Quaresmini, Doreen te Raa, Gianluigi Reda, Gian Matteo Rigolin, Rosa Ruchlemer, Amit Shrestha, Martin Šimkovič, Martin Špaček, Paolo Sportoletti, Oana Stanca Ciocan, Tamar Tadmor, Elisabeth Vandenberghe, Marzia Varettoni, Candida Vitale, Ellen Van Der Spek, Michel Van Gelder, Ewa Wasik-Szczepanek, Lucrecia Yáñez, Mohamed A Yassin, Marta Coscia, Barbara Eichhorst, Alessandro Rambaldi, Niki Stavroyianni, Livio Trentin, Kostas Stamatopoulos, Paolo Ghia
Journal: Blood
Blood (2022) 140 (Supplement 1): 2333–2337.
https://doi.org/10.1182/blood-2022-163259
Published: 2022