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Journal Articles

Patients with Chronic Lymphocytic Leukemia Carrying t(14;19) Display a Distinctive Transcriptomic Profile and Adverse Outcome, Which Might be Overcome Continuous Therapy with BTK Inhibitors. an Italian Campus CLL and Eric Study

Andrea Visentin, Enrico Gaffo, Moritz Furstenau, Jennifer A. Woyach, Panagiotis Baliakas, Kerry A Rogers, Cecelia Miller, Claudia Haferlach, Karla Plevova, David Graham Oscier, Zadie Davis, Florence Nguyen Khac, Eleonora Roncaglia, Gian Matteo Rigolin, Anastasia Athanasiadou, Fanny Baran-Marszak, Alberto Valiente, Maria Jose Terol, Pau Abrisqueta, Blanca Espinet, Anna Puiggros, Annalisa Martines, Laura Bonaldi, Francesca Romana Mauro, Lydia Scarfo, Thomas Chatzikonstantinou, Eugen Tausch, Karl Anton Kreuzer, Arnon P. Kater, Francesc Bosch, Michael Doubek, Panayiotis Panayiotidis, Olga Kalashnikova, Federica Frezzato, Monica Facco, Valeria Ruocco, Alessia Buratin, Silvia Orsi, Alessandro Cellini, Francesco Angotzi, Chiara Adele Cavarretta, Ivan Zatta, Andrea Serafin, Robin Foa, Barbara F. Eichhorst, Antonio Cuneo, Kostas Stamatopoulos, Paolo Ghia, Stefania Bortoluzzi, Livio Trentin
Journal: Blood
Blood (2023) 142 (Supplement 1): 3275.
https://doi.org/10.1182/blood-2023-174569
Published: 2023
Journal Articles

The Proliferative History Index, Epicmit, Derived from Genome-Wide Epigenomic Profiling, Is a Key Driver of Clinical Survival in Splenic Marginal Zone Lymphoma

Helen Parker, Amatta Mirandari, Carolina Jaramillo-Oquendo, Marti Duran-Ferrer, Ben Stevens, Lara Buermann, Harindra Eranthi Amarasinghe, Jaya Thomas, Louise J. Carr, Shama Syeda, Methusha Sakthipakan, Marina Parry, Zadie Davies, Neil McIver-Brown, Aliki Xochelli, Sarah Ennis, Lydia Scarfo, Paolo Ghia, Christina H. Kalpadakis, Gerassimos Pangalis, Davide Rossi, Simon Wagner, Matthew Ahearne, Marc Seifert, Christoph Plass, Dieter Weichenhan, Eva Kimby, Lesley Ann Sutton, Richard Rosenquist, Francesco Forconi, Kostas Stamatopoulos, Marta Salido, Ana Ferrer, Catherine Thieblemont, David Graham Oscier, Renata Walewska, Matthew JJ Rose-Zerilli, Jane Gibson, Iñaki I. Martin Subero, Christopher C. Oakes, Dean J. Bryant, Jonathan C. Strefford
Journal: Blood
Blood (2023) 142 (Supplement 1): 4370.
https://doi.org/10.1182/blood-2023-174481
Published: 2023
Journal Articles

DNA Methylation-Based Classification of Hairy Cell Leukemia and Splenic B Cell Lymphoma

Kyoko Yamaguchi, Salma Abdelbaky, Evgeny Arons, Matthew Cross, Yue-Zhong Wu, Christoph Weigel, Mirela Iulia Anghelina, Helen Parker, Artur Kibler, Marta Salido, Constance Regina Baer, Manja Meggendorfer, Benjamin Durham, Omar Abdel-Wahab, Seema A Bhat, Gerard Lozanski, Kerry A Rogers, Yonghong Wang, Paul S. Meltzer, Sunil Iyengar, Sascha Dietrich, Thorsten Zenz, James S. Blachly, Aurelie Verney, Lucile Baseggio, Alexandra Traverse-Glehen, Marc Seifert, Ralf Kuppers, Richard Burack, Clive S Zent, Versha Banerji, James B. Johnston, David Graham Oscier, Renata Walewska, Kostas Stamatopoulos, Torsten Haferlach, Ana Ferrer, Catherine Thieblemont, Francesco Forconi, Robert Kreitman, Michael R. Grever, Jonathan C. Strefford, Piers Blombery, Christopher C. Oakes
Journal: Blood
Blood (2023) 142 (Supplement 1): 174.
https://doi.org/10.1182/blood-2023-189835
Published: 2023
Journal Articles

Telomere Length and DNA Methylation Epitype Both Provide Independent Prognostic Information in CLL Patients; Data from the UK CLL4, Arctic and Admire Clinical Trials

Louise J. Carr, Kevin Norris, Helen Parker, Anna Nilsson-Takeuchi, Dean J. Bryant, Harindra Eranthi Amarasinghe, Latha Kadalayil, Monica Else, Tomasz Wojdacz, Andrew Pettitt, Peter Hillmen, Anna Schuh, Renata Walewska, Duncan M. Baird, David Graham Oscier, Christopher C. Oakes, Jane Gibson, Chris Pepper, Jonathan C. Strefford
Journal: Blood
Blood (2023) 142 (Supplement 1): 6514.
https://doi.org/10.1182/blood-2023-177575
Published: 2023
Journal Articles

Genetic and phenotypic attributes of splenic marginal zone lymphoma

Ferdinando Bonfiglio, Alessio Bruscaggin, Francesca Guidetti, Lodovico Terzi di Bergamo, Martin Faderl, Valeria Spina, Adalgisa Condoluci, Luisella Bonomini, Gabriela Forestieri, Ricardo Koch, Deborah Piffaretti, Katia Pini, Maria Cristina Pirosa, Micol Giulia Cittone, Alberto Arribas, Marco Lucioni, Guido Ghilardi, Wei Wu, Luca Arcaini, Maria Joao Baptista, Gabriela Bastidas, Silvia Bea, Renzo Boldorini, Alessandro Broccoli, Marco Matteo Buehler, Vincenzo Canzonieri, Luciano Cascione, Luca Ceriani, Sergio Cogliatti, Paolo Corradini, Enrico Derenzini, Liliana Devizzi, Sascha Dietrich, Angela Rita Elia, Fabio Facchetti, Gianluca Gaidano, Juan Fernando Garcia, Bernhard Gerber, Paolo Ghia, Maria Gomes da Silva, Giuseppe Gritti, Anna Guidetti, Felicitas Hitz, Giorgio Inghirami, Marco Ladetto, Armando Lopez-Guillermo, Elisa Lucchini, Antonino Maiorana, Roberto Marasca, Estella Matutes, Veronique Meignin, Michele Merli, Alden Moccia, Manuela Mollejo, Carlos Montalban, Urban Novak, David Graham Oscier, Francesco Passamonti, Francesco Piazza, Stefano Pizzolitto, Alessandro Rambaldi, Elena Sabattini, Gilles Salles, Elisa Santambrogio, Lydia Scarfò, Anastasios Stathis, Georg Stüssi, Julia T. Geyer, Gustavo Tapia, Corrado Tarella, Catherine Thieblemont, Thomas Tousseyn, Alessandra Tucci, Giorgio Vanini, Carlo Visco, Umberto Vitolo, Renata Walewska, Francesco Zaja, Thorsten Zenz, Pier Luigi Zinzani, Hossein Khiabanian, Arianna Calcinotto, Francesco Bertoni, Govind Bhagat, Elias Campo, Laurence De Leval, Stefan Dirnhofer, Stefano A. Pileri, Miguel A. Piris, Alexandra Traverse-Glehen, Alexander Tzankov, Marco Paulli, Maurilio Ponzoni, Luca Mazzucchelli, Franco Cavalli, Emanuele Zucca, Davide Rossi
Journal: Blood
Blood (2022) 139 (5): 732–747.
https://doi.org/10.1182/blood.2021012386
Published: 2022
Includes: Supplemental data
Journal Articles

A Systematic Search Into The Role Of IGHV Gene Replacement In Shaping The Immunoglobulin Repertoire Of Chronic Lymphocytic Leukemia

Sophia Yancopoulos, PhD, Xiao-Jie Yan, MD PhD, Andreas Agathangelidis, Wentian Li, Ph.D., Chrysoula Belessi, Paolo Ghia, MD, PhD, Richard Rosenquist, MD, PhD, Frederic Davi, MD, PhD, David Graham Oscier, MD, Sarka Pospisilova, Panagiotis Panagiotidis, MD, Lin Huang, PhD, Zhixin Zhang, PhD, Steven L. Allen, MD, Jaqueline C. Barrientos, MD, Jonathan E. Kolitz, MD, Kanti R. Rai, MD, Kostas Stamatopoulos, MD, Nicholas Chiorazzi, MD
Journal: Blood
Blood (2013) 122 (21): 4129.
https://doi.org/10.1182/blood.V122.21.4129.4129
Published: 2013
Journal Articles

Stereotyped B-cell receptors in one-third of chronic lymphocytic leukemia: a molecular classification with implications for targeted therapies

Andreas Agathangelidis, Nikos Darzentas, Anastasia Hadzidimitriou, Xavier Brochet, Fiona Murray, Xiao-Jie Yan, Zadie Davis, Ellen J. van Gastel-Mol, Cristina Tresoldi, Charles C. Chu, Nicola Cahill, Veronique Giudicelli, Boris Tichy, Lone Bredo Pedersen, Letizia Foroni, Lisa Bonello, Agnieszka Janus, Karin Smedby, Achilles Anagnostopoulos, Helene Merle-Beral, Nikolaos Laoutaris, Gunnar Juliusson, Paola Francia di Celle, Sarka Pospisilova, Jesper Jurlander, Christian Geisler, Athanasios Tsaftaris, Marie-Paule Lefranc, Anton W. Langerak, David Graham Oscier, Nicholas Chiorazzi, Chrysoula Belessi, Frederic Davi, Richard Rosenquist, Paolo Ghia, Kostas Stamatopoulos
Journal: Blood
Blood (2012) 119 (19): 4467–4475.
https://doi.org/10.1182/blood-2011-11-393694
Published: 2012
Includes: Supplemental data
Journal Articles

SNP-Arrays Provide New Insights Into the Pathogenesis of Richter Syndrome (RS)

Andrea Rinaldi, Ekaterina Chigrinova, Ivo Kwee, Davide Rossi, Paola MV Rancoita, PhD, Jonathan C. Strefford, BSc, PhD, David Graham Oscier, MD, Kostas Stamatopoulos, MD, Theodora Papadaki, Francoise Berger, Ken H. Young, MD, Fiona Murray, Richard Rosenquist, MD, PhD, Timothy C. Greiner, MD, Wing C. Chan, MD, Luca Arcaini, Marco Lucioni, Roberto Marasca, Giorgio Inghirami, Marco Ladetto, MD, Francesco Forconi, Sergio Cogliatti, Hana Votavova, Steven H. Swerdlow, MD, Stephan Stilgenbauer, MD, Miguel Piris, MD, Andras Matolcsy, MD, Dominic Spagnolo, Eugene Nikitin, Alberto Zamò, Valter Gattei, Laura Pasqualucci, MD, Emanuele Zucca, MD, Gianluca Gaidano, Francesco Bertoni
Journal: Blood
Blood (2011) 118 (21): 263.
https://doi.org/10.1182/blood.V118.21.263.263
Published: 2011
Journal Articles

Deletion Size Influences Clinical Outcome In Patients with Chronic Lymphocytic Leukemia; 13q Deletion Anatomy, Cooperating Lesions and Cancer Pathogenesis

Helen Parker, PhD, Matthew JJ Rose-Zerilli, PhD, Anton Parker, BSc, Tracy Chaplin, Anne Catherine Gardiner, BSc, Mike Griffiths, Andrew Collins, PhD, Bryan D Young, BSc, PhD, David Graham Oscier, Jonathan C. Strefford, BSc, PhD
Journal: Blood
Blood (2010) 116 (21): 757.
https://doi.org/10.1182/blood.V116.21.757.757
Published: 2010
Journal Articles

Sequential SNP6.0 Microarray Analysis In Rai Stage 0 CLL Patients with Either Stable or Progressive Identifies Genomic Evolution In Both Cohorts

Matthew JJ Rose-Zerilli, PhD, Miqdad Rajibali, BSc, Helen Parker, PhD, Anton Parker, BSc, Anne Catherine Gardiner, BSc, Zadie Davis, PhD, Sarah Mold, BSc, Sharron Glide, BSc, Tracy Chaplin, Bryan D Young, BSc, PhD, David Graham Oscier, Jonathan C. Strefford, BSc, PhD
Journal: Blood
Blood (2010) 116 (21): 1696.
https://doi.org/10.1182/blood.V116.21.1696.1696
Published: 2010
Journal Articles

Polyclonal Serum FLC Levels: a Simple Risk Stratification Model for Identifying Aggressive Stage A CLL.

Guy Pratt, Alison Levoguer, Jeffrey Faint, Chris Fegan, Chris Pepper, David Graham Oscier, MD, Anne Gardiner, Stephen Harding, PhD
Journal: Blood
Blood (2010) 116 (21): 4608.
https://doi.org/10.1182/blood.V116.21.4608.4608
Published: 2010
Journal Articles

The Composition of the B Cell Receptor Repertoire In 7428 Cases of Chronic Lymphocytic Leukemia: One Third Stereotyped, Two Thirds Heterogeneous - What Does This Mean?

Andreas Agathaggelidis, Nikos Darzentas, Anastasia Hadzidimitriou, Xavier Brochet, Fiona Murray, Xiao-Jie Yan, Zadie Davis, Ellen van Gastel, Cristina Tresoldi, Charles C Chu, PhD, Nicola Cahill, Veronique Giudicelli, Boris Tichy, Lone Bredo Pedersen, Letizia Foroni, Paola Francia di Celle, Agnieszka Janus, Karin Smedby, Achilles Anagnostopoulos, Helene Merle-Beral, Nikolaos Laoutaris, Gunnar Juliusson, Sarka Pospisilova, Jesper Jurlander, Athanasios Tsaftaris, Marie-Paule Lefranc, Anton W. Langerak, David Graham Oscier, Nicholas Chiorazzi, Chrysoula Belessi, Frederic Davi, Richard Rosenquist, Paolo Ghia, Kostas Stamatopoulos
Journal: Blood
Blood (2010) 116 (21): 43.
https://doi.org/10.1182/blood.V116.21.43.43
Published: 2010
Journal Articles

CD5 Negative Mononuclear Lymphocytosis;a Precursor for Splenic Marginal Zone Lymphoma?

Anne Catherine Gardiner, Zadie Davis, Rachel A Ibbotson, Sharron Glide, Sarah Mould, Neil McIver-Brown, David Graham Oscier
Journal: Blood
Blood (2010) 116 (21): 3113.
https://doi.org/10.1182/blood.V116.21.3113.3113
Published: 2010
Journal Articles

13q Deletion Size Predicts Disease Progression and Response to Treatment in Patients with Chronic Lymphocytic Leukaemia.

Jonathan C Strefford, PhD, Helen Parker, PhD, Anton Parker, BSc, Hazel Robinson, PhD, Tracy Chaplin, MSc, Xiao-He Chen, PhD, David Bunyan, PhD, Anne Gardiner, BSc, Bryan D Young, PhD, David Graham Oscier, MD
Journal: Blood
Blood (2009) 114 (22): 671.
https://doi.org/10.1182/blood.V114.22.671.671
Published: 2009
Journal Articles

Mutational Status of the TP53 Gene as a Predictor of Response and Survival in CLL Patients with and without 17p Deletion

David Gonzalez, PhD, Pilar Martinez, MD, PhD, Rachel Wade, Sarah Lorna Hockley, PhD, Vasantha Brito-Babapulle, PhD, David Graham Oscier, MD, Estella Matutes, MD, PhD, Claire E Dearden, Sue Richards, Daniel Catovsky, MD, Gareth J Morgan, MD, PhD
Journal: Blood
Blood (2008) 112 (11): 784.
https://doi.org/10.1182/blood.V112.11.784.784
Published: 2008
Journal Articles

Chronic Lymphocytic Leukemia Cells Recognize Conserved Epitopes Associated with Apoptosis and Catabolic Chemical Modifications

Rosa Catera, Gregg J. Silverman, Katerina Hatzi, Till Seiler, Sebastien Didier, Lu Zhang, MA, Maxime Hervé, Eric Meffre, David Graham Oscier, MD, Helen Vlassara, Yifang Chen, Steven L. Allen, Kanti R. Rai, MD, Charles C. Chu, PhD, Nicholas Chiorazzi, MD
Journal: Blood
Blood (2008) 112 (11): 3150.
https://doi.org/10.1182/blood.V112.11.3150.3150
Published: 2008
Journal Articles

Epigenetic Regulation of ZAP70 in Chronic Lymphocytic Leukemia.

Anton Parker, Shilu Amin, Tricia Zwiefelhofer, Ben Gregory, Helen White, PhD, Oliver Giles Best, PhD, Nick Cross, PhD, Jelena Mann, PhD, Mathias Ehrich, MD, David Graham Oscier, MD
Journal: Blood
Blood (2008) 112 (11): 2246.
https://doi.org/10.1182/blood.V112.11.2246.2246
Published: 2008
Journal Articles

A Novel Functional Assay Using Etoposide Plus Nutlin 3, FISH and Mutational Analysis Detects Heterogeneity of ATM/p53 Pathway Alterations in CLL.

Giles Best, PhD, Anne Gardiner, BSc, Rachel Ibbotson, PhD, Aneela Majid, PhD, Renata Walewska, MD, Belinda Austen, MD, Tanja Stankovic, PhD, Martin Dyer, MD, David Graham Oscier, MD
Journal: Blood
Blood (2006) 108 (11): 2795.
https://doi.org/10.1182/blood.V108.11.2795.2795
Published: 2006
Journal Articles

The Utility of V617F JAK2 Analysis for Patients with Erythrocytosis or Thrombocytosis in the General Hospital.

David Graham Oscier, MD, Amy Jones, BSc, Louise Wallis, SRN, Joe Chacko, MD, Nicholas C.P. Cross, PhD
Journal: Blood
Blood (2006) 108 (11): 3630.
https://doi.org/10.1182/blood.V108.11.3630.3630
Published: 2006
Journal Articles

Defining the 10 Year Risk of Disease Progression in Stage A0 CLL.

Anne Gardiner, BSc, Zadie Davis, MSc, Parker Anton, BSc, Giles Best, PhD, Rachel Ibbotson, PhD, Sarah Mould, BSc, Sharron Glide, BSc, Peter Thomas, PhD, Jenny Orchard, MD, David Graham Oscier, MD
Journal: Blood
Blood (2006) 108 (11): 2772.
https://doi.org/10.1182/blood.V108.11.2772.2772
Published: 2006