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Journal Articles

Acalabrutinib ± Obinutuzumab Vs Obinutuzumab + Chlorambucil in Treatment-Naive Chronic Lymphocytic Leukemia: 6-Year Follow-up of Elevate-TN

Jeff P. Sharman, Miklos Egyed, Wojciech Jurczak, Alan Skarbnik, Krish Patel, Ian W. Flinn, Manali Kamdar, Talha Munir, Renata Walewska, Marie Hughes, Laura Maria Fogliatto, Yair Herishanu, Versha Banerji, George Follows, Patricia A. Walker, Karin Karlsson, Paolo Ghia, Ann Janssens, Florence Cymbalista, John C. Byrd, Emmanuelle Ferrant, Alessandra Ferrajoli, William G. Wierda, Veerendra Munugalavadla, Catherine Wangui Wachira, Chuan-Chuan Wun, Jennifer A. Woyach
Journal: Blood
Blood (2023) 142 (Supplement 1): 636.
https://doi.org/10.1182/blood-2023-174750
Published: 2023
Journal Articles

DNA Methylation-Based Classification of Hairy Cell Leukemia and Splenic B Cell Lymphoma

Kyoko Yamaguchi, Salma Abdelbaky, Evgeny Arons, Matthew Cross, Yue-Zhong Wu, Christoph Weigel, Mirela Iulia Anghelina, Helen Parker, Artur Kibler, Marta Salido, Constance Regina Baer, Manja Meggendorfer, Benjamin Durham, Omar Abdel-Wahab, Seema A Bhat, Gerard Lozanski, Kerry A Rogers, Yonghong Wang, Paul S. Meltzer, Sunil Iyengar, Sascha Dietrich, Thorsten Zenz, James S. Blachly, Aurelie Verney, Lucile Baseggio, Alexandra Traverse-Glehen, Marc Seifert, Ralf Kuppers, Richard Burack, Clive S Zent, Versha Banerji, James B. Johnston, David Graham Oscier, Renata Walewska, Kostas Stamatopoulos, Torsten Haferlach, Ana Ferrer, Catherine Thieblemont, Francesco Forconi, Robert Kreitman, Michael R. Grever, Jonathan C. Strefford, Piers Blombery, Christopher C. Oakes
Journal: Blood
Blood (2023) 142 (Supplement 1): 174.
https://doi.org/10.1182/blood-2023-189835
Published: 2023
Journal Articles

Clime: CLL Immune Micro-Environment and Risk of Infections Pre- and Post-Diagnosis: A Population-Based Study

Versha Banerji, David E Dawe, Lin Xue, Oliver Bucher, Lin Yang, James B. Johnston, Spencer Bruce Gibson, Kathleen Decker
Journal: Blood
Blood (2023) 142 (Supplement 1): 7396.
https://doi.org/10.1182/blood-2023-187573
Published: 2023
Journal Articles

The Economic Impact of Treatment Sequencing in the Management of Chronic Lymphocytic Leukemia in Canada Using Venetoclax Plus Obinutuzumab

Kimberly Guinan, Jean Lachaine, Nancy Paul Roc, Sarah-Jane Bull, Dipti Tankala, Stéphane Barakat, Christopher M. Hillis, Versha Banerji
Journal: Blood
Blood (2022) 140 (Supplement 1): 2157–2158.
https://doi.org/10.1182/blood-2022-167235
Published: 2022
Journal Articles

Quality of Life in Patients with Chronic Lymphocytic Leukemia Initiating Venetoclax in Routine Clinical Practice across Canada: Results from the Devote Study

Andrew Aw, Versha Banerji, Sarah-Jane Bull, Pierre-André Fournier, Anthea Peters, Carolyn Owen
Journal: Blood
Blood (2022) 140 (Supplement 1): 12425–12426.
https://doi.org/10.1182/blood-2022-156749
Published: 2022
Journal Articles

IL-4 Mediated Upregulation of AMPK/SIRT1/PGC-1α Signalling Pathway Is Bypassed By Mitochondrial Complex I Downregulation By NAMPT Inhibition in Venetoclax and Ibrutinib Treated CLL Cells

Subir Roy Chowdhury, Cheryl Peltier, Eileen M. McMillan-Ward, Ryan Saleh, Tricia Choquette, Maxim Skorodinsky, Kira Peters, Edwin Nguyen, Amandeep Singh, Eric D. Bouchard, James B. Johnston, Aaron Marshall, James Thliveris, Spencer Bruce Gibson, Sara J. Israels, Versha Banerji
Journal: Blood
Blood (2021) 138 (Supplement 1): 2616.
https://doi.org/10.1182/blood-2021-146947
Published: 2021
Journal Articles

Tumor Lysis Syndrome: Incidence, Mitigation and Management in Patients with Chronic Lymphocytic Leukemia Initiating Venetoclax in Routine Clinical Practice (DEVOTE) across Canada

Versha Banerji, Nizar Abdel-Samad, Andrew Aw, Sarah-Jane Bull, Pierre-André Fournier, Nathalie Johnson, Nicole B. Laferriere, Paola Lembo, Christina H Pelizon, Anthea Peters, Carolyn Owen
Journal: Blood
Blood (2021) 138 (Supplement 1): 3744.
https://doi.org/10.1182/blood-2021-146001
Published: 2021
Journal Articles

Natural history of monoclonal B-cell lymphocytosis among relatives in CLL families

CME Clinical Trials & Observations
Susan L. Slager, Mark C. Lanasa, Gerald E. Marti, Sara J. Achenbach, Nicola J. Camp, Fatima Abbasi, Neil E. Kay, Celine M. Vachon, James R. Cerhan, James B. Johnston, Timothy G. Call, Kari G. Rabe, Geffen Kleinstern, Nicholas J. Boddicker, Aaron D. Norman, Sameer A. Parikh, Jose F. Leis, Versha Banerji, Danielle M. Brander, Martha Glenn, Alessandra Ferrajoli, Karen Curtin, Esteban Braggio, Tait D. Shanafelt, Mary L. McMaster, J. Brice Weinberg, Curtis A. Hanson, Neil E. Caporaso
Journal: Blood
Blood (2021) 137 (15): 2046–2056.
https://doi.org/10.1182/blood.2020006322
Published: 2021
Includes: Supplemental data
Journal Articles

High Transfusion Dependence and Serum Ferritin but Not Transferrin Saturation Predict Inferior Clinical Outcomes in Patients with MDS

Jennifer Teichman, MD, Michelle Geddes, MD, Nancy Zhu, MD, Mary-Margaret Keating, MD FRCPC, Mitchell Sabloff, MSc,MDFRCPC, Grace Christou, MD, Brian Leber, MD, Dina Khalaf, BSc, MSc, MD, Eve St-Hilaire, MD, Nicholas Finn, MD, April Shamy, MD, Karen W.L. Yee, MD, John M. Storring, MD, Thomas J. Nevill, MD, Robert Delage, MD, Mohamed Elemary, MD, Versha Banerji, MD, Lee Mozessohn, MD, Lisa Chodirker, MD, Liying Zhang, PhD, Mohammed Siddiqui, Anne Parmentier, BA, Heather A. Leitch, MD, Rena J. Buckstein, MD FRCPC
Journal: Blood
Blood (2020) 136 (Supplement 1): 47–48.
https://doi.org/10.1182/blood-2020-140065
Published: 2020
Journal Articles

Fatigue, However Measured, Continues to Refine Prognosis in Higher Risk MDS: An MDS-CAN Study

Irina Amitai, MD, Michelle Geddes, MD, Nancy Zhu, MD, Mary-Margaret Keating, MD FRCPC, Mitchell Sabloff, Grace Christou, MD, Brian Leber, MD, Dina Khalaf, BSc, MSc, MD, Heather A. Leitch, MD, Eve St-Hilaire, MD, Nicholas Finn, MD, April Shamy, MD, Karen W.L. Yee, MD, John M. Storring, MD, Thomas J. Nevill, MD, Robert Delage, MD, Mohamed Elemary, MD, Versha Banerji, MD, Lisa Chodirker, MD, Lee Mozessohn, MD, Anne Parmentier, BA, Mohammed Siddiqui, Alexandre Mamedov, Liying Zhang, PhD, Rena J. Buckstein, MD FRCPC
Journal: Blood
Blood (2020) 136 (Supplement 1): 41–43.
https://doi.org/10.1182/blood-2020-141635
Published: 2020
Journal Articles

ELEVATE TN: Phase 3 Study of Acalabrutinib Combined with Obinutuzumab (O) or Alone Vs O Plus Chlorambucil (Clb) in Patients (Pts) with Treatment-Naive Chronic Lymphocytic Leukemia (CLL)

Jeff P. Sharman, MD, Versha Banerji, MD, Laura Maria Fogliatto, MD PhD, Yair Herishanu, MD, Talha Munir, MD, Renata Walewska, George Follows, Karin Karlsson, MD, Paolo Ghia, MD PhD, Gillian Corbett, Patricia Walker, MBBS, Miklos Egyed, Wojciech Jurczak, MD PhD, Gilles Salles, MD PhD, Ann Janssens, Florence Cymbalista, MD PhD, William G. Wierda, MD PhD, Steven Coutre, MD, John M. Pagel, MD PhD DSc, Alan Skarbnik, MD, Manali Kamdar, MD, Jennifer Woyach, MD, Raquel Izumi, PhD, Veerendra Munugalavadla, PhD, Priti Patel, MD, Min Hui Wang, PhD, Sofia Wong, John C. Byrd, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 31.
https://doi.org/10.1182/blood-2019-128404
Published: 2019
Journal Articles

Persistent Red Blood Cell (RBC) Transfusion Is Associated with Increased Mortality Risk in Transfusion-Dependent (TD) Patients with Myelodysplastic Syndromes (MDS) with Ring Sideroblasts (RS+)

Rena Buckstein, MD FRCPC, Nancy Zhu, MD, Mary-Margaret Keating, MD, Brian Leber, MD, Lisa Chodirker, MD, Mitchell Sabloff, Grace Cristou, Heather A. Leitch, MD, Eve St. Hilaire, Nicholas Finn, MD, Karen W.L. Yee, MD, Mohamed Elemary, MD, Versha Banerji, MD, Martha Lenis, Aksharh Kirubananthaan, Fei Fei Liu, Derek Tang, PhD BSPharm, Chris Westcott, Vicky Wei-Hsuen Huang, Di Wang, Chris Cameron, Jessica Morison, Paul Spin, Alexandre Mamedov
Journal: Blood
Blood (2019) 134 (Supplement_1): 3012.
https://doi.org/10.1182/blood-2019-123684
Published: 2019
Journal Articles

Intermittent Transfusion Independence Is Associated with Improved Overall Survival in Patients with Transfusion Dependent MDS

Rena Buckstein, MD FRCPC, Lisa Chodirker, MD, Michelle Geddes, MD, Nancy Zhu, MD, Grace Christou, MD, Mitchell Sabloff, MD, Mary-Margaret Keating, MD, Brian Leber, MD, Heather A. Leitch, MD, Karen W.L. Yee, MD, Eve St-Hilaire, MD, Nicholas Finn, MD, Thomas J. Nevill, MD, John Storring, MD, April Shamy, MD, Versha Banerji, MD, Mohamed Elemary, MD, Robert Delage, MD, Alexandre Mamedov, Liying Zhang, PhD, Aksharh Kirubananthaan, Richard A. Wells, MD DPhil
Journal: Blood
Blood (2019) 134 (Supplement_1): 5416.
https://doi.org/10.1182/blood-2019-129464
Published: 2019
Journal Articles

Ibrutinib in Combination with Venetoclax Decreases Mitochondrial Bioenergetics through the Impaired BTK, AKT and AMPK/SIRT/PGC-1α Signaling Pathway in CLL

Subir Roy Chowdhury, MD PhD, Amandeep Singh, MSc, Edwin Nguyen, Aaron Marshall, PhD, James B. Johnston, MD, Spencer Bruce Gibson, PhD, Versha Banerji, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1282.
https://doi.org/10.1182/blood-2019-127562
Published: 2019
Journal Articles

Prognostic Performance of Frailty Measures in MDS Patients Treated with Hypomethylating Agents

Bo Angela Wan, BA, MPhil, Richard A. Wells, MD DPhil, Lisa Chodirker, MD, Ken Rockwood, MD, Michelle Geddes, MD, Nancy Zhu, MD, Grace Christou, MD MSc, Mitchell Sabloff, MSc,MDFRCPC, Mary-Margaret Keating, MD, Brian Leber, MD, Heather A. Leitch, MD, Karen W.L. Yee, MD, Eve St-Hilaire, MD, Nicholas Finn, MD, John Storring, MD, Thomas J. Nevill, MD, April Shamy, MD, Versha Banerji, MD, Mohamed Elemary, MD, Robert Delage, MD, Alexandre Mamedov, Martha Lenis, Liying Zhang, PhD, Aksharh Kirubananthaan, Shabbir Alibhai, Rena Buckstein, MD FRCPC
Journal: Blood
Blood (2019) 134 (Supplement_1): 4245.
https://doi.org/10.1182/blood-2019-128949
Published: 2019
Journal Articles

Venetoclax in Combination with NAMPT Inhibitors Decreases Mitochondrial Bioenergetics through the Impaired AMPK/SIRT/PGC1α Signaling Pathway in CLL

Subir Roy Chowdhury, MD PhD, Saleh Ryan, BSc, Cheryl Peltier, BSc, Mandy Squires, CCRP, HIT, Donna Hewitt, R.N., Paul Fernyhough, PhD, Spencer Bruce Gibson, PhD, Versha Banerji, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1368.
https://doi.org/10.1182/blood-2018-99-112210
Published: 2018
Journal Articles

Health Related Quality of Life Remains Stable over Time in Myelodysplastic Syndrome: An MDS-CAN Prospective Study

Danielle N. Blunt, BMBS, Richard A. Wells, MD DPhil, Martha Lenis, Lisa Chodirker, MD, Michelle Geddes, MD, Nancy Zhu, MD, Jill Fulcher, MD PhD, Mitchell Sabloff, MD, Mary-Margaret Keating, MD, Brian Leber, MD, Heather A. Leitch, MD, Karen W.L. Yee, MD, Eve St-Hilaire, MD, Nicholas G. Finn, MD, April Shamy, MD, Mohamed Elemary, MD, Robert Delage, MD, Ken Rockwood, MD, Versha Banerji, MD, Alexandre Mamedov, Liying Zhang, PhD, Rena Buckstein, MD FRCPC
Journal: Blood
Blood (2018) 132 (Supplement 1): 4850.
https://doi.org/10.1182/blood-2018-99-114327
Published: 2018
Journal Articles

A Descriptive Analysis of Obinutuzumab Usage in a Single Canadian Centre

Nicole Bourrier, BSc, Ivan Landego, MD, Mandy Squires, CCRP, HIT, Oliver Bucher, Zeb Aurangzeb, Erin Streu, MSN, RN, CON (C), Theresa Whiteside, RN, BN, CON (C), Irena Hibbert, RN, BN, CON (C), Marc Geirnaert, BSc Pharm, David Dawe, MD FRCPC, Spencer Bruce Gibson, PhD, James B. Johnston, MD FRCP, Versha Banerji, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 5838.
https://doi.org/10.1182/blood-2018-99-113422
Published: 2018
Journal Articles

A Phase II Clinical Trial of the Pan PI3K Inhibitor, Buparlisib, for the Treatment of Relapsed and Refractory Chronic Lymphocytic Leukemia: Canadian Cancer Trials Group IND.216

Sarit Assouline, MD, Lilian Amrein, PhD, Versha Banerji, MD FRCP, Stephen Caplan, MD, Carolyn Jane Owen, MD FRCPC, Wanda Hasegawa, MD, Sue Robinson, MD, Sudeep Shavikumar, MD, Anca Prica, MD FRCP(C), Anthea Peters, MSc, MD FRCPC, Linda Hagerman, Laura Rodriguez, Tanya Skamene, MD, Lawrence Panasci, MD, Bingshu E. Chen, Annette E Hay
Journal: Blood
Blood (2017) 130 (Supplement 1): 4319.
https://doi.org/10.1182/blood.V130.Suppl_1.4319.4319
Published: 2017
Journal Articles

Importance of Mitochondrial Metabolism As a Selective Therapeutic Approach in Chronic Lymphocytic Leukemia Patients

Subir Roy Chowdhury, MD PhD, Saleh Ryan, BSc, Donna Hewitt, R.N., Mandy Squires, CCRP, HIT, Garry Shen, MD PhD, Versha Banerji, MD FRCP
Journal: Blood
Blood (2017) 130 (Supplement 1): 2545.
https://doi.org/10.1182/blood.V130.Suppl_1.2545.2545
Published: 2017