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Journal Articles

Phase I Clinical Study of PA3-17 Injection in Patients with Relapsed/Refractory T-Lymphoblastic Leukemia/Lymphoma

Lijuan Hu, Hui Yu, Heng Mei, Dehui Zou, Yaqing Li, Danying Liao, Wei Liu, Yan Xu, Lei Zhang, Xudong Zhang, Zhenchang Sun, Xinhua Wang, Min Wang, Fengtao You, Huimin Meng, Tian Wang, Bozhen Zhang, Lin Yang, Mingzhi Zhang, Xiaojun Huang
Journal: Blood
Blood (2023) 142 (Supplement 1): 3471.
https://doi.org/10.1182/blood-2023-178484
Published: 2023
Journal Articles

Update Results of a Phase II Trial of Venetoclax in Combination with Azacitidine and Chidamide in Relapsed/Refractory Acute Myeloid Leukemia

Jie Zha, Ying Wang, Zhenling Li, Zhijuan Lin, Yun Cai, Tiejun Gong, Wei Yang, Siting Xie, Zhenqi Huang, Pengcheng SHI, Lin Fu, Jinghua Wang, Xiangjun Fu, Xianqi Feng, Liping Su, Jianmin Luo, Lin Yang, Biyun Chen, Ying Xie, Yu Zhu, Xin Du, Yirong Jiang, Zhifeng Li, Bing Xu
Journal: Blood
Blood (2023) 142 (Supplement 1): 4274.
https://doi.org/10.1182/blood-2023-182832
Published: 2023
Journal Articles

Inflammatory Signatures Define a New High-Risk T-Lineage ALL Subtype

Mark Gower, Ximing Li, Alicia Aguilar-Navarro, Brian Lin, Minerva Fernandez, Gibran Edun, Mursal Nader, Andrea Arruda, Anne Maria Tierens, Elvin Wagenblast, Lin Yang, Ho Seok Lee, Sanam Loghavi, John E. Dick, Mark D. Minden, Johann K. Hitzler, Courtney L Jones, Gregory Schwartz, Igor Dolgalev, Soheil Jahangiri, Anastasia N. Tikhonova
Journal: Blood
Blood (2023) 142 (Supplement 1): 2969.
https://doi.org/10.1182/blood-2023-182412
Published: 2023
Journal Articles

Clime: CLL Immune Micro-Environment and Risk of Infections Pre- and Post-Diagnosis: A Population-Based Study

Versha Banerji, David E Dawe, Lin Xue, Oliver Bucher, Lin Yang, James B. Johnston, Spencer Bruce Gibson, Kathleen Decker
Journal: Blood
Blood (2023) 142 (Supplement 1): 7396.
https://doi.org/10.1182/blood-2023-187573
Published: 2023
Journal Articles

U2AF1 S34F Mutation Promote Megakaryopoiesis and Fibrogenesis in MDS

Wenjun Zhang, Jinqin Liu, Lin Yang, Yiru Yan, Tiejun Qin, Zefeng Xu, Gang Huang, Bing Li, Zhijian Xiao
Journal: Blood
Blood (2023) 142 (Supplement 1): 5685.
https://doi.org/10.1182/blood-2023-185678
Published: 2023
Journal Articles

Renal Response of Selinexor, Pomalidomide, Bortezomib and Dexamethasone in Newly Diagnosed Multiple Myeloma Patients with Renal Impairment: A Prospective, Open-Label, Multicenter, Phase 2 Study

Huixing Zhou, Long Chang, Jing Jia, Jie Ma, Hua Xue, Hao Li, Wenrong Huang, Hebing Zhou, Jingnan Sun, Liping Su, Yanping Ma, Huang Hongming, Hongmei Jing, Zhenling Li, Guangyu Ma, Guohong Su, Jihao Zhou, Biyun Chen, LI Bao, Zhihua Zhang, Lin Yang, Haiping Yang, Yanhong Zhao, Chunyan Sun, Qingming Wang, Qimuge Saiyin, Da Gao, Xiaoxia Chu, Zhenfang Xi, Weiwei Tian, Xuliang Shen, Shi Minxia, Jin Zhang, Yi Chen, Jingbo Xu, Yao Liu, Hongling Peng, Weijun Fu, Jun Luo, Zhenyu Li, Hui-Han Wang, Xiaobo Wang, Xiuli Sun, Jinqiao Zhang, Wei WANG, Yan Yan, Yafei Wang, Xin Du, Yonghuai Feng, Yi Wang, Ying Sun, Liye Zhong, Li Gao, Wenming Chen, Jian Li, Wen Gao
Journal: Blood
Blood (2023) 142 (Supplement 1): 4754.
https://doi.org/10.1182/blood-2023-180736
Published: 2023
Journal Articles

Mechanisms of response and resistance to combined decitabine and ipilimumab for advanced myeloid disease

Clinical Trials & Observations
Livius Penter, Yang Liu, Jacquelyn O. Wolff, Lin Yang, Len Taing, Aashna Jhaveri, Jackson Southard, Manishkumar Patel, Nicole M. Cullen, Kathleen L. Pfaff, Nicoletta Cieri, Giacomo Oliveira, Seunghee Kim-Schulze, Srinika Ranasinghe, Rebecca Leonard, Taylor Robertson, Elizabeth A. Morgan, Helen X. Chen, Minkyung H. Song, Magdalena Thurin, Shuqiang Li, Scott J. Rodig, Carrie Cibulskis, Stacey Gabriel, Pavan Bachireddy, Jerome Ritz, Howard Streicher, Donna S. Neuberg, F. Stephen Hodi, Matthew S. Davids, Sacha Gnjatic, Kenneth J. Livak, Jennifer Altreuter, Franziska Michor, Robert J. Soiffer, Jacqueline S. Garcia, Catherine J. Wu
Journal: Blood
Blood (2023) 141 (15): 1817–1830.
https://doi.org/10.1182/blood.2022018246
Published: 2023
Includes: Supplemental data
Journal Articles

Preclinical Studies and Phase II Trial of Venetoclax in Combination with Chidamide and Azacitidine in Relapsed/Refractory Acute Myeloid Leukemia

Jie Zha, Hui Zhou, Mengya Zhong, Ying Wang, Xin Du, Tiejun Gong, Zhijuan Lin, Yun Cai, Siting Xie, Chendi Xie, XianQi Feng, ZhenQi Huang, Liping Su, Jianmin Luo, Lin Yang, Zhenling Li, Bi-yun Chen, Ying Xie, Yu Zhu, Pengcheng Shi, Zhifeng Li, Yirong Jiang, Bing Xu
Journal: Blood
Blood (2022) 140 (Supplement 1): 3292–3293.
https://doi.org/10.1182/blood-2022-165261
Published: 2022
Journal Articles

Mechanisms of Response and Resistance to Combination Decitabine and Ipilimumab for Transplant Naïve and Post-Transplant AML/MDS

Livius Penter, Yang Liu, Lin Yang, Len Taing, Aashna Jhaveri, Jackson Southard, Manishkumar Patel, Jacquelyn Wolff, Nicole Cullen, Kathleen Pfaff, Nicoletta Cieri, Giacomo Oliveira, Seunghee Kim-Schulze, Srinika Ranasinghe, Rebecca Leonard, Taylor Robertson, Helen Chen, Magdalena Thurin, Shuqiang Li, Scott J. Rodig, Carrie Cibulskis, Stacey Gabriel, Jerome Ritz, Howard Streicher, Donna S. Neuberg, Stephen Hodi, Sacha Gnjatic, Kenneth J Livak, Jennifer Altreuter, Franziska Michor, Robert J Soiffer, Jacqueline S. Garcia, Catherine J. Wu
Journal: Blood
Blood (2022) 140 (Supplement 1): 10198–10199.
https://doi.org/10.1182/blood-2022-157339
Published: 2022
Journal Articles

Real-World Treatment Outcomes and Toxicities of Outpatient R-CHOP/R-DHAP in Patients with Mantle Cell Lymphoma Eligible for Autologous Stem Cell Transplant

Jiayu Yang, Pamela Skrabek, Leonard Minuk, Catherine Moltzan, Rami Kotb, Lin Yang, Roopesh R. Kansara
Journal: Blood
Blood (2022) 140 (Supplement 1): 11983–11984.
https://doi.org/10.1182/blood-2022-170680
Published: 2022
Journal Articles

Micheliolide Exerts Therapeutic Effect in Myeloproliferative Neoplasms through Binding to STAT3 and STAT5 Proteins and Inhibiting Their Activities

Huijun Huang, Jinqin Liu, Lin Yang, Yue Chen, Robert Peter Gale, Zhijian Xiao
Journal: Blood
Blood (2022) 140 (Supplement 1): 3065–3066.
https://doi.org/10.1182/blood-2022-165225
Published: 2022
Journal Articles

A National, Multicenter, Retrospective Study of Castleman Disease Implementing Cdcn Criteria: 'severe Imcd' Is Indeed Severe

Lu Zhang, Yujun Dong, Hongling Peng, Hao Li, Mingzhi Zhang, Hui-Han Wang, Qinhua Liu, Liping Su, Liye Zhong, Wenjun Wu, Liang Huang, Xiaojing Yan, Lei Fan, Wenjiao Tang, Zhenling Li, Lintao Bi, Yan Li, Guangxun Gao, Li Gao, Ting-Bo Liu, Yongqiang Wei, Yao Liu, Yu Li, Hui Zhou, Chunyan Sun, Wenbin Qian, Dehui Zou, Huilai Zhang, Kaiyang Ding, Xiaobo Wang, Ou Bai, Wenrong Huang, Bing Chen, Lin Yang, Jia Song, Da Gao, Tong Chen, Jun Luo, Shuye Wang, Liangming Ma, Jian Li
Journal: Blood
Blood (2022) 140 (Supplement 1): 3609–3611.
https://doi.org/10.1182/blood-2022-158675
Published: 2022
Journal Articles

Phase 1 TRANSCEND CLL 004 study of lisocabtagene maraleucel in patients with relapsed/refractory CLL or SLL

Clinical Trials & Observations
Tanya Siddiqi, Jacob D. Soumerai, Kathleen A. Dorritie, Deborah M. Stephens, Peter A. Riedell, Jon Arnason, Thomas J. Kipps, Heidi H. Gillenwater, Lucy Gong, Lin Yang, Ken Ogasawara, Jerill Thorpe, William G. Wierda
Journal: Blood
Blood (2022) 139 (12): 1794–1806.
https://doi.org/10.1182/blood.2021011895
Published: 2022
Includes: Supplemental data
Journal Articles

The Impact of the Immunophenotyping Characteristics of Patients' Peripheral Blood on the Manufacturing and Clinical Outcome of CD7-Targeted Chimeric Antigen Receptor T Cells

Mingzhi Zhang, Xiaorui Fu, Huimin Meng, Min Wang, Yu Wang, Guifang Pan, Lei Zhang, Ling Li, Xin Li, Xinhua Wang, Zhenchang Sun, Hui Yu, Zhaoming Li, Feifei Nan, Yu Chang, Zhiyuan Zhou, Jiaqin Yan, Jiwei Li, Xiaolong Wu, Yanmei Zhao, Yu-Sheng Chen, Fengtao You, Dan Chen, Tingting Zhang, Bozhen Zhang, Lin Yang
Journal: Blood
Blood (2021) 138 (Supplement 1): 3830.
https://doi.org/10.1182/blood-2021-147632
Published: 2021
Journal Articles

A Single-Arm, Open-Label, Pilot Trial of Autologous CD7-CAR-T Cells for CD7 Positive Relapsed and Refractory T-Lymphoblastic Leukemia/Lymphoma

Mingzhi Zhang, Xiaorui Fu, Huimin Meng, Min Wang, Yu Wang, Lei Zhang, Ling Li, Xin Li, Xinhua Wang, Zhenchang Sun, Hui Yu, Zhaoming Li, Feifei Nan, Yu Chang, Zhiyuan Zhou, Jiaqin Yan, Jiwei Li, Xiaolong Wu, Guifang Pan, Yanmei Zhao, Yu-Sheng Chen, Fengtao You, Lin Yang
Journal: Blood
Blood (2021) 138 (Supplement 1): 3829.
https://doi.org/10.1182/blood-2021-149999
Published: 2021
Journal Articles

A zinc transporter, transmembrane protein 163, is critical for the biogenesis of platelet dense granules

Yefeng Yuan, Teng Liu, Xiahe Huang, Yuanying Chen, Weilin Zhang, Ting Li, Lin Yang, Quan Chen, Yingchun Wang, Aihua Wei, Wei Li
Journal: Blood
Blood (2021) 137 (13): 1804–1817.
https://doi.org/10.1182/blood.2020007389
Published: 2021
Includes: Supplemental data
Journal Articles

Transcend CLL 004: Phase 1 Cohort of Lisocabtagene Maraleucel (liso-cel) in Combination with Ibrutinib for Patients with Relapsed/Refractory (R/R) Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL)

William G. Wierda, MD PhD, Kathleen A. Dorritie, MD, Javier Munoz, MD, Deborah M. Stephens, DO, Scott R. Solomon, MD, Heidi H. Gillenwater, MD, Lucy Gong, PharmD, Lin Yang, PhD, Ken Ogasawara, PhD MPH, Jerill Thorpe, BS, Tanya Siddiqi, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 39–40.
https://doi.org/10.1182/blood-2020-140622
Published: 2020
Journal Articles

Updated Follow-up of Patients with Relapsed/Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma Treated with Lisocabtagene Maraleucel in the Phase 1 Monotherapy Cohort of Transcend CLL 004, Including High-Risk and Ibrutinib-Treated Patients

Tanya Siddiqi, MD, Jacob D. Soumerai, MD, Kathleen A. Dorritie, MD, Deborah M. Stephens, DO, Peter A. Riedell, MD, Jon E. Arnason, MD, Thomas J. Kipps, MD PhD, Heidi H. Gillenwater, MD, Lucy Gong, PharmD, Lin Yang, PhD, Ken Ogasawara, PhD MPH, William G. Wierda, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 40–41.
https://doi.org/10.1182/blood-2020-140491
Published: 2020
Journal Articles

Rapid Undetectable MRD (uMRD) Responses in Patients with Relapsed/Refractory (R/R) Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL) Treated with Lisocabtagene Maraleucel (liso-cel), a CD19-Directed CAR T Cell Product: Updated Results from Transcend CLL 004, a Phase 1/2 Study Including Patients with High-Risk Disease Previously Treated with Ibrutinib

Tanya Siddiqi, MD, Jacob D. Soumerai, MD, Kathleen A. Dorritie, MD, Deborah M. Stephens, DO, Peter A. Riedell, MD, Jon E. Arnason, MD, Thomas J. Kipps, MD PhD, Heidi H. Gillenwater, MD, Lucy Gong, PharmD, Jason A. Dubovsky, PhD, Julie Rytlewski, PhD, Lin Yang, William G. Wierda, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 503.
https://doi.org/10.1182/blood-2019-127603
Published: 2019
Journal Articles

Automation Platform for CAR-T Manufacturing: The Benefits and the Clinical Outcomes

Min Wang, PhD, Fengtao You, PhD, Xingbing Wang, MD, Bingzong Li, MD PhD, Hanying Xu, MS, Yu Wang, MS, Guifang Pan, MS, Song Sun, MS, Huimin Meng, MD PhD, Yanmei Zhao, MS, Yu-Sheng Chen, PhD, Bozhen Zhang, MBA, Lin Yang, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1960.
https://doi.org/10.1182/blood-2019-123656
Published: 2019