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Journal Articles

Roles for Heme Synthesis in the Maintenance of Hematopoietic Stem and Progenitor Cells

Yan Yan, Hiroki Kato, Sayaka Sano, Eijiro Furukawa, Daigo Michimata, Yuya Tanaka, Kazuki Sakurai, Koichi Onodera, Satoshi Ichikawa, Tohru Fujiwara, Yasushi Onishi, Noriko Fukuhara, Hisayuki Yokoyama, Hideo Harigae
Journal: Blood
Blood (2023) 142 (Supplement 1): 2682.
https://doi.org/10.1182/blood-2023-174202
Published: 2023
Journal Articles

Discriminating Risk of Anticoagulant-Related Bleeding in Ambulatory Cancer Patients on Thromboprophylaxis

Kristen M. Sanfilippo, Yan Yan, Marc Carrier, Brian F. Gage
Journal: Blood
Blood (2023) 142 (Supplement 1): 567.
https://doi.org/10.1182/blood-2023-190795
Published: 2023
Journal Articles

RUNX1 Mutation Does Not Significantly Impact the Outcome of Newly Diagnosedadult AML: A Retrospective Study of Chinese AML Patients

Chao-Ling Wan, Yuan-Hong Huang, Si-Man Huang, Tong-Tong Zhang, Kai-Wen Tan, Yan Qiu, Xiang-Dong Shen, Shuai-Shuai Ge, Han-Yu Cao, Yan-Yan Li, Songbai Liu, Qiao-Cheng Qiu, Haiping Dai, Sheng-Li Xue
Journal: Blood
Blood (2023) 142 (Supplement 1): 4216.
https://doi.org/10.1182/blood-2023-185390
Published: 2023
Journal Articles

Pulmonary Infection Associated with Immune Dysfunction Predicting Dismal Prognosis in Patients with Myelodysplastic Syndrome Accompanied By TP53 Gene Abnormalities

Yi Chen, Jing Zheng, Yan Yan Qiu, Zhengjun Wu, Xiaofeng Luo, Liangfang Zhu, Yanjuan Lin
Journal: Blood
Blood (2023) 142 (Supplement 1): 6470.
https://doi.org/10.1182/blood-2023-174347
Published: 2023
Journal Articles

Venetoclax, Cladribine and Cytarabine for the Treatment of Relapse/Refractory Acute Lymphoblastic Leukemia: Interim Analysis of a Phase 2 Trial

Yan-yan Li, Hai-xia Zhou, Si-man Huang, Chao-Ling Wan, Ming-zhu Xu, Wen-jie Gong, Chong-Sheng Qian, De-pei Wu, Haiping Dai, Sheng-Li Xue
Journal: Blood
Blood (2023) 142 (Supplement 1): 1506.
https://doi.org/10.1182/blood-2023-185312
Published: 2023
Journal Articles

Regional Genetic Heterogeneity Among Patients with Pyruvate Kinase Deficiency

Paola Bianchi, Elisa Fermo, Kevin H.M. Kuo, Dagmar Pospíšilová, Andreas Glenthoej, Carl Lander, Eduard J. Van Beers, Bertil Glader, Joan-Lluis Vives Corrons, Stefan W Eber, Yan Yan, Bryan McGee, Janet H Ford, Saliha Yilmaz, Rachael F. Grace
Journal: Blood
Blood (2023) 142 (Supplement 1): 5203.
https://doi.org/10.1182/blood-2023-181834
Published: 2023
Journal Articles

Hematopoietic Stem/Progenitor Cell Intrinsic SAM Synthesis Is Required to Prevent p53 Pathway Activation By Maintaining DNA Stability

Eijiro Furukawa, Hiroki Kato, Sayaka Sano, Yan Yan, Daigo Michimata, Yuya Tanaka, Kazuki Sakurai, Koichi Onodera, Satoshi Ichikawa, Noriko Fukuhara, Yasushi Onishi, Hisayuki Yokoyama, Daisuke Saigusa, Tohru Fujiwara, Kazuhiko Igarashi, Hideo Harigae
Journal: Blood
Blood (2023) 142 (Supplement 1): 4049.
https://doi.org/10.1182/blood-2023-180384
Published: 2023
Journal Articles

Renal Response of Selinexor, Pomalidomide, Bortezomib and Dexamethasone in Newly Diagnosed Multiple Myeloma Patients with Renal Impairment: A Prospective, Open-Label, Multicenter, Phase 2 Study

Huixing Zhou, Long Chang, Jing Jia, Jie Ma, Hua Xue, Hao Li, Wenrong Huang, Hebing Zhou, Jingnan Sun, Liping Su, Yanping Ma, Huang Hongming, Hongmei Jing, Zhenling Li, Guangyu Ma, Guohong Su, Jihao Zhou, Biyun Chen, LI Bao, Zhihua Zhang, Lin Yang, Haiping Yang, Yanhong Zhao, Chunyan Sun, Qingming Wang, Qimuge Saiyin, Da Gao, Xiaoxia Chu, Zhenfang Xi, Weiwei Tian, Xuliang Shen, Shi Minxia, Jin Zhang, Yi Chen, Jingbo Xu, Yao Liu, Hongling Peng, Weijun Fu, Jun Luo, Zhenyu Li, Hui-Han Wang, Xiaobo Wang, Xiuli Sun, Jinqiao Zhang, Wei WANG, Yan Yan, Yafei Wang, Xin Du, Yonghuai Feng, Yi Wang, Ying Sun, Liye Zhong, Li Gao, Wenming Chen, Jian Li, Wen Gao
Journal: Blood
Blood (2023) 142 (Supplement 1): 4754.
https://doi.org/10.1182/blood-2023-180736
Published: 2023
Journal Articles

The Role of Radiotherapy in Patients with Refractory Hodgkin Lymphoma after Brentuximab Vedotin and -/or Immune Checkpoint Inhibitors

Ting-Bo Liu, Xiaofan Li, Rui-Zhi Zhao, Han Shao, Gui-Qing Shi, Yan-Yan Qiu, Tian-Lan Tang, Yu-Ping Lin, Si-Lin Chen, Cheng Huang, Si-Qin Liao, Jin-Hua Chen, Hai-Ying Fu, Jian-Zhi Liu, Jian-Zhen Shen, Ben-Hua Xu, Yu-jing Zhang, Yong Yang
Journal: Blood
Blood (2023) 142 (Supplement 1): 6189.
https://doi.org/10.1182/blood-2023-184773
Published: 2023
Journal Articles

Transcription Factor GATA2 Is Inevitable for the Survival and Proper Differentiation of Thymic Multipotent Progenitor Cells By Gene Expression Orchestration

Sayaka Sano, Hiroki Kato, Yan Yan, Eijiro Furukawa, Daigo Michimata, Yuya Tanaka, Kazuki Sakurai, Koichi Onodera, Satoshi Ichikawa, Noriko Fukuhara, Yasushi Onishi, Hisayuki Yokoyama, Tohru Fujiwara, Hideo Harigae
Journal: Blood
Blood (2023) 142 (Supplement 1): 1182.
https://doi.org/10.1182/blood-2023-178454
Published: 2023
Journal Articles

Renal Response of Pomalidomide with Bortezomib and Dexamethasone in Newly Diagnosed Multiple Myeloma Patients with Renal Impairment: A Prospective, Open-Label, Multicenter, Phase 2 Study

Yuan Jian, Long Chang, Mingxia Shi, Ying Sun, Xiaoxia Chu, Hua Xue, Wenrong Huang, Xuliang Shen, Jie Ma, Guorong Jia, Yaqing Feng, Zhenfang Xi, Yanhong Zhao, Yanping Ma, Jing Xiao, Guangyu Ma, Qingming Wang, Li Bao, Yujun Dong, Hebing Zhou, Chunyan Sun, Guohong Su, Yan Yan, Saiyin Qimuge, Liping Su, Jingnan Sun, Weiwei Tian, Xiuli Sun, Hongmei Jing, Da Gao, Wenming Chen, Jian Li, Wen Gao
Journal: Blood
Blood (2022) 140 (Supplement 1): 10167–10169.
https://doi.org/10.1182/blood-2022-159361
Published: 2022
Journal Articles

Age of Onset of Complications in Patients with Pyruvate Kinase Deficiency: Analysis from the Peak Registry

Andreas Glenthøj, Rachael F. Grace, Eduard J. van Beers, Joan-Lluis Vives Corrons, Bert Glader, Kevin H.M. Kuo, Carl Lander, Dagmar Pospíšilová, Hitoshi Kanno, Jean Williams, Yan Yan, Bryan McGee, Paola Bianchi
Journal: Blood
Blood (2022) 140 (Supplement 1): 5323–5325.
https://doi.org/10.1182/blood-2022-156205
Published: 2022
Journal Articles

Comorbidities and Complications in Pediatric Patients with Pyruvate Kinase Deficiency Enrolled in the Peak Registry

Rachael F. Grace, Andreas Glenthøj, Carl Lander, Eduard J. van Beers, Hitoshi Kanno, Joan-Lluis Vives Corrons, Paola Bianchi, Dagmar Pospíšilová, Jean Williams, Yan Yan, Bryan McGee, Bert Glader
Journal: Blood
Blood (2022) 140 (Supplement 1): 5316–5318.
https://doi.org/10.1182/blood-2022-168799
Published: 2022
Journal Articles

Characterizing Iron Overload By Age in Patients Diagnosed with Pyruvate Kinase Deficiency - a Descriptive Analysis from the Peak Registry

Paola Bianchi, Rachael F. Grace, Joan-Lluis Vives Corrons, Bert Glader, Andreas Glenthøj, Hitoshi Kanno, Kevin H.M. Kuo, Carl Lander, D. Mark Layton, Dagmar Pospíŝilová, Vip Viprakasit, Jean Williams, Yan Yan, Bryan McGee, Eduard J. Van Beers
Journal: Blood
Blood (2021) 138 (Supplement 1): 3074.
https://doi.org/10.1182/blood-2021-147294
Published: 2021
Journal Articles

Baseline Characteristics of Patients in Peak: A Global, Longitudinal Registry of Patients with Pyruvate Kinase Deficiency

Rachael F. Grace, MD, Audra Boscoe, PhD, Chris Bowden, MD, Bertil Glader, MD PhD, Hitoshi Kanno, MDPhD, D. Mark Layton, MB BS, Eduard van Beers, MD PhD, Joan-Lluis Vives Corrons, MD PhD, Yan Yan, MS, Paola Bianchi, BSc, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 39–40.
https://doi.org/10.1182/blood-2020-136634
Published: 2020
Journal Articles

Comorbidities and Complications in Adults with Pyruvate Kinase Deficiency

Audra N. Boscoe, PhD, Yan Yan, MS, Elizabeth Hedgeman, PhD, Eduard J. van Beers, MD PhD, Hanny Al-Samkari, MD, Wilma Barcellini, MD, Stefan W. Eber, MD, Bertil Glader, MD PhD, Hassan M. Yaish, MD, Satheesh Chonat, MD, Jennifer A. Rothman, MD, Mukta Sharma, MD MPH, Nina Kollmar, MD, Christine M. Knoll, MD, Kevin H. M. Kuo, MDMSc,FRCPC, Janet L. Kwiatkowski, MD MSCE, Yves D. Pastore, MD, Alexis A Thompson, MD MPH, Yaddanapudi Ravindranath, MBBS, Ellis J. Neufeld, MD, Heng Wang, MD PhD, Susanne Holzhauer, MD MSc, Vicky R. Breakey, BSc,MDFRCPC, Madeleine M. Verhovsek, MD FRCPC, Joachim B. Kunz, MD, Sujit Sheth, MD, Melissa A. McNaull, MD, Melissa J. Rose, DO, Dagmar Pospisilova, MD PhD, Jenny M. Despotovic, DO, Rachael F. Grace, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2175.
https://doi.org/10.1182/blood-2019-123069
Published: 2019
Journal Articles

The Dosage of Pten Is Critical in Determining the Disease Severity - a Mouse Model Differentially Mimicking JMML and CMML

Yan Yan, MD, Natalia C Colorado, MD, Shelly Lensing, MS, Delli R Robinson, Nicholas J Baltz, Daohong Zhou, MD, Peter Dean Emanuel, MD, Y. Lucy Liu, MD PhD
Journal: Blood
Blood (2016) 128 (22): 1550.
https://doi.org/10.1182/blood.V128.22.1550.1550
Published: 2016
Journal Articles

JQ1, a Potential Therapeutic Molecule for Myeloid Leukemia with PTEN Deficiency

Nicholas J Baltz, Natalia C Colorado, MD, Yan Yan, MD, Shelly Lensing, MS, Delli Robinson, BA, Michele H. Cottler-Fox, MD, Jason E Farrar, MD, Peter Dean Emanuel, MD, Y. Lucy Liu, MD PhD
Journal: Blood
Blood (2016) 128 (22): 5899.
https://doi.org/10.1182/blood.V128.22.5899.5899
Published: 2016
Journal Articles

Timing of the loss of Pten protein determines disease severity in a mouse model of myeloid malignancy

Y. Lucy Liu, Yan Yan, Cody Webster, Lijian Shao, Shelly Y. Lensing, Hongyu Ni, Wei Feng, Natalia Colorado, Rupak Pathak, Zhifu Xiang, Martin Hauer-Jensen, Shaoguang Li, Daohong Zhou, Peter D. Emanuel
Journal: Blood
Blood (2016) 127 (15): 1912–1922.
https://doi.org/10.1182/blood-2015-05-646216
Published: 2016
Includes: Supplemental data
Journal Articles

Investigating Effects of Cyclosporine on Eltrombopag Pharmacokinetics in Healthy Volunteers: A Phase 1 Crossover, Drug-Drug Interaction Study

Jianping Zhang, PhD, Connie L. Erickson-Miller, PhD, Geoffrey Chan, MD, Yan Yan Zhou, PhD
Journal: Blood
Blood (2015) 126 (23): 4791.
https://doi.org/10.1182/blood.V126.23.4791.4791
Published: 2015