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Journal Articles

Notch1 regulates hepatic thrombopoietin production

Yueyue Sun, Huan Tong, Xiang Chu, Yingying Li, Jie Zhang, Yangyang Ding, Sixuan Zhang, Xiang Gui, Chong Chen, Mengdi Xu, Zhenyu Li, Elizabeth E. Gardiner, Robert K. Andrews, Lingyu Zeng, Kailin Xu, Jianlin Qiao
Journal: Blood
Blood (2024) 143 (26): 2778–2790.
https://doi.org/10.1182/blood.2023023559
Published: 2024
Includes: Supplemental data
Journal Articles

Efficacy Outcomes and Characteristics of Patients with Multiple Myeloma (MM) Who Achieved Sustained Minimal Residual Disease Negativity after Treatment with Equecabtagene Autoleucel (Eque-cel, CT103A) in Fumanba-1

Chunrui Li, Lu-Gui Qiu, Di Wang, Yongping Song, He Huang, Jianyong Li, Bing Chen, Jing Liu, Yujun Dong, Kai Hu, Peng Liu, Xi Zhang, Jianqing Mi, Zhenyu Li, Kaiyang Ding, Shiyue Zhang, Guang Hu, Wen Wang
Journal: Blood
Blood (2023) 142 (Supplement 1): 761.
https://doi.org/10.1182/blood-2023-173427
Published: 2023
Journal Articles

Efficacy and Safety of BCMA-Specific CAR T Cell-Based Therapy in Relapsed/Refractory Multiple Myeloma Patients with Extramedullary Disease

Yuekun Qi, Jianlin Qiao, Zhenyu Li, Kailin Xu
Journal: Blood
Blood (2023) 142 (Supplement 1): 4844.
https://doi.org/10.1182/blood-2023-173256
Published: 2023
Journal Articles

A Phase 1b Study Evaluating the Safety and Efficacy of AK117 (anti-CD47 monoclonal antibody) in Combination with Azacitidine in Patients with Treatment-Naïve Acute Myeloid Leukemia

Huafeng Wang, Qike Zhang, Qingliang Teng, Zhenyu Li, Hong Liu, Zhongmin Maxwell Wang, Baiyong Li, Yu Xia, Jie Jin
Journal: Blood
Blood (2023) 142 (Supplement 1): 4280.
https://doi.org/10.1182/blood-2023-180618
Published: 2023
Journal Articles

Renal Response of Selinexor, Pomalidomide, Bortezomib and Dexamethasone in Newly Diagnosed Multiple Myeloma Patients with Renal Impairment: A Prospective, Open-Label, Multicenter, Phase 2 Study

Huixing Zhou, Long Chang, Jing Jia, Jie Ma, Hua Xue, Hao Li, Wenrong Huang, Hebing Zhou, Jingnan Sun, Liping Su, Yanping Ma, Huang Hongming, Hongmei Jing, Zhenling Li, Guangyu Ma, Guohong Su, Jihao Zhou, Biyun Chen, LI Bao, Zhihua Zhang, Lin Yang, Haiping Yang, Yanhong Zhao, Chunyan Sun, Qingming Wang, Qimuge Saiyin, Da Gao, Xiaoxia Chu, Zhenfang Xi, Weiwei Tian, Xuliang Shen, Shi Minxia, Jin Zhang, Yi Chen, Jingbo Xu, Yao Liu, Hongling Peng, Weijun Fu, Jun Luo, Zhenyu Li, Hui-Han Wang, Xiaobo Wang, Xiuli Sun, Jinqiao Zhang, Wei WANG, Yan Yan, Yafei Wang, Xin Du, Yonghuai Feng, Yi Wang, Ying Sun, Liye Zhong, Li Gao, Wenming Chen, Jian Li, Wen Gao
Journal: Blood
Blood (2023) 142 (Supplement 1): 4754.
https://doi.org/10.1182/blood-2023-180736
Published: 2023
Journal Articles

The Resistance Mechanism to BET-Protac in Multiple Myeloma

Jianlin Qiao, Yang Liu, Li Nian, Congyue Wang, Mingxiao Yu, Wenwen Zhang, Zhenyu Li, Chong Chen
Journal: Blood
Blood (2023) 142 (Supplement 1): 6584.
https://doi.org/10.1182/blood-2023-188004
Published: 2023
Journal Articles

Preliminary Results of a Phase 2 Study of IMM01 Combined with Azacitidine (AZA) As the First-Line Treatment in Adult Patients with Higher Risk Myelodysplastic Syndromes (MDS)

Wei Yang, Sujun Gao, Xiaojing Yan, Rong Guo, Lijie Han, Fei Li, Yafei Wang, Junmin Li, Chunkang Chang, Haiping Yang, Ronghua Hu, Hongyan Tong, Xingli Zhao, Qiubai Li, Jingdong Zhang, Xin Du, Sanfang Tu, Cheng Zhang, Congmeng Lin, Xin Du, Zhenling Li, Ligen Liu, Zhenyu Li, Zheng Dong, Yixuan Yang, Qiying Lu, Wenzhi Tian, Zhijian Xiao
Journal: Blood
Blood (2023) 142 (Supplement 1): 320.
https://doi.org/10.1182/blood-2023-174420
Published: 2023
Journal Articles

Pharmacokinetics, Efficacy and Safety Evaluation of FRSW107 in Previously Treated Hemophilia a Patients: A Multicentre, Open-Label, Non-Randomized Phase III Study

Feng Xue, Hu Zhou, Yun Chen, Jing Sun, Xiaojing Zeng, Chenghao Jin, Pingchong Lei, Zhenyu Li, Yaming Xi, Lirong Sun, Zhongguang Cui, Xielan Zhao, Linhua Yang, Bangshuo Zhang, Aizong Shen, Runhui Wu, Xiaolin Wang, Ling Liu, Yuhua Wang, Lizhi Sun, Yan Xia, Weichuan Mo, Dong Yuan, Jiwei Lou, Taiping Gan, Chengli Hu, Chen Ling, Hongsheng Su, Yali Wang, Baolin Tang, Renchi Yang
Journal: Blood
Blood (2022) 140 (Supplement 1): 8468–8469.
https://doi.org/10.1182/blood-2022-158760
Published: 2022
Journal Articles

A Phase 1b Study to Evaluate Safety and Efficacy of IBI188 in Combination with Azacitidine (AZA) As a First-Line Treatment in Subjects with Newly Diagnosed Higher Risk Myelodysplastic Syndrome

Miao Miao, Depei WU, Shuangfeng Xie, Mei Hong, ChunKang Chang, Li Yu, Sujun Gao, Yan Li, Yuhua Li, Zunmin Zhu, Baolin Tang, Bingzong Li, Haiping Yang, Jishi Wang, Ling Qin, Rong Fu, Fei Li, Liangming Ma, Qifa Liu, Xin Du, Zhongxing Jiang, Zhenyu Li, Aijun Liu, Hongyan Tong, Jun Ma, Li Liu, Qingchi Liu, Yajing Xu, Hui Zhou, Yan Wang, Jianlin Chen, Ziru Niu, Mingxia Chen, Zhijian Xiao
Journal: Blood
Blood (2022) 140 (Supplement 1): 4045–4046.
https://doi.org/10.1182/blood-2022-155901
Published: 2022
Journal Articles

Updated Results of Fumanba-1: A Phase 1b/2 Study of a Novel Fully Human B-Cell Maturation Antigen-Specific CAR T Cells (CT103A) in Patients with Relapsed and/or Refractory Multiple Myeloma

Chunrui Li, Di Wang, Baijun Fang, Yongping Song, He Huang, Jianyong Li, Dehui Zou, Bing Chen, Jing Liu, Yujun Dong, Hanyun Ren, Kai Hu, Peng Liu, Xi Zhang, Jian-Qing Mi, Zhenyu Li, Kaiyang Ding, Jue Wang, Liting Chen, Aining Xu, Songbai Cai, Jingwen Zeng, Jingjing Guo, Hongyu Gui, Wen Wang, Lugui Qiu
Journal: Blood
Blood (2022) 140 (Supplement 1): 7435–7436.
https://doi.org/10.1182/blood-2022-166465
Published: 2022
Journal Articles

Protein tyrosine phosphatase PTPN22 negatively modulates platelet function and thrombus formation

Xiamin Wang, Guangyu Wei, Yangyang Ding, Xiang Gui, Huan Tong, Xiaoqi Xu, Sixuan Zhang, Zengtian Sun, Wen Ju, Yue Li, Ruosi Yao, Qingyu Wu, Zhihao Lu, Chunling Fu, Zhenyu Li, Si Zhang, Elizabeth E. Gardiner, Robert K. Andrews, Hu Hu, Lingyu Zeng, Kailin Xu, Jianlin Qiao
Journal: Blood
Blood (2022) 140 (9): 1038–1051.
https://doi.org/10.1182/blood.2022015554
Published: 2022
Includes: Supplemental data
Journal Articles

Efficacy and safety of CD19-specific CAR T cell–based therapy in B-cell acute lymphoblastic leukemia patients with CNSL

Clinical Trials & Observations
Yuekun Qi, Mingfeng Zhao, Yongxian Hu, Ying Wang, Ping Li, Jiang Cao, Ming Shi, Jiaqi Tan, Meng Zhang, Xia Xiao, Jieyun Xia, Sha Ma, Jianlin Qiao, Zhiling Yan, Hujun Li, Bin Pan, Wei Sang, Depeng Li, Zhenyu Li, Jianfeng Zhou, He Huang, Aibin Liang, Junnian Zheng, Kailin Xu
Journal: Blood
Blood (2022) 139 (23): 3376–3386.
https://doi.org/10.1182/blood.2021013733
Published: 2022
Includes: Supplemental data
Journal Articles

A Phase 1/2 Study of a Novel Fully Human B-Cell Maturation Antigen-Specific CAR T Cells (CT103A) in Patients with Relapsed and/or Refractory Multiple Myeloma

Chunrui Li, Di Wang, Yongping Song, Jianyong Li, He Huang, Bing Chen, Jing Liu, Kai Hu, Hanyun Ren, Xi Zhang, Zhenyu Li, Dehui Zou, Qingsong Yin, Lijuan Chen, Yongxian HU, Yong Xu, Qian Cheng, Yuelu Guo, Yujun Dong, Li Gao, Aining Xu, Songbai Cai, Wen Wang, Ming Wu, Jue Wang, Liting Chen, Jianfeng Zhou, Lugui Qiu
Journal: Blood
Blood (2021) 138 (Supplement 1): 547.
https://doi.org/10.1182/blood-2021-152576
Published: 2021
Journal Articles

The Type II Glycoengineered Humanized Anti-CD20 Monoclonal Antibody MIL62 Combined with Lenalidomide in Chinese Patients with Relapsed/Refractory Follicular Lymphoma and Marginal Zone Lymphoma: Results of a Multicenter, Single-Arm, Phase 1b/2 Trial

Yuankai Shi, Yan Qin, Yongping Song, Keshu Zhou, Hui Zhou, Hongmei Jing, Ying Xiang, Zhao Wang, Zhen Wang, Aimin Zang, Ou Bai, Zhenyu Li, Huilai Zhang
Journal: Blood
Blood (2021) 138 (Supplement 1): 1351.
https://doi.org/10.1182/blood-2021-146440
Published: 2021
Journal Articles

Risk Factors and Characteristics of CRS in CAR-T Treatment

Yan Zhiling, MD, Zhang Huanxin, MD, Ying Wang, Jiang Cao, MD, Jianlin Qiao, PhD, Deipeng Li, MD, Bin Pan, MD, Qingyun Wu, PhD, Zhenyu Li, MD, Kailin Xu, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4462.
https://doi.org/10.1182/blood-2019-129777
Published: 2019
Journal Articles

Inflammasome Activation Promotes Deep Vein Thrombosis through Pyroptosis

Yan Zhang, Guoying Zhang, Cui Jian, Congqing Wu, PhD, Nigel Mackman, PhD, Susan Smyth, MD PhD, Yinan Wei, Zhenyu Li, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3644.
https://doi.org/10.1182/blood-2019-130439
Published: 2019
Journal Articles

Combination of Anti-CD19 and Anti-CD20 Chimeric Antigen Receptor T Cells for Relapsed and Refractory Diffuse Larger B Cell Lymphoma: An Open-Label, Single-Arm, Phase Ⅰ/Ⅱ Trial

Wei Sang, MD, Ming Shi, Jingjing Yang, Jiang Cao, MD, Linyan Xu, PhD, Dongmei Yan, Xuguang Song, Cai Sun, Depeng Li, Feng Zhu, Zhenyu Li, MD, Junnian Zheng, Jianlin Qiao, PhD, Kailin Xu, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1590.
https://doi.org/10.1182/blood-2019-127640
Published: 2019
Journal Articles

Kinetics of Immune Reconstitution after CD19 CAR-T Cell Therapy in ALL Patients

Ying Wang, Jiang Cao, MD, Yan Zhiling, MD, Jianlin Qiao, PhD, Deipeng Li, MD, Zhenyu Li, MD, Kailin Xu, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1301.
https://doi.org/10.1182/blood-2019-127808
Published: 2019
Journal Articles

Abnormal Coagulation Function in Chimeric Antigen Receptor T Cell Treatment of Hematologic Malignancies

Kunming Qi, Hai Cheng, MD, Jiang Cao, MD PhD, Wei Chen, Jianlin Qiao, PhD, Lingyu Zeng, MD,PhD, Zhenyu Li, Kailin Xu, MD, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 5019.
https://doi.org/10.1182/blood-2018-99-114074
Published: 2018
Journal Articles

Arf6 controls platelet spreading and clot retraction via integrin α IIb β 3 trafficking

Yunjie Huang, Smita Joshi, Binggang Xiang, Yasunori Kanaho, Zhenyu Li, Beth A. Bouchard, Carole L. Moncman, Sidney W. Whiteheart
Journal: Blood
Blood (2016) 127 (11): 1459–1467.
https://doi.org/10.1182/blood-2015-05-648550
Published: 2016
Includes: Supplemental data