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Journal Articles

Role of ferroptosis in aGVHD-induced liver tissue damage: Mediation by Acsl4-regulated PUFA-pls

Shufen Wang, Yingying Ding, Hongyu Zhou, Xiaoyan Yue, Huiqiao Chen, Ruoyu Dong, He Huang, Haowen Xiao

Blood (2025) 146 (Supplement 1): 5872.

https://doi.org/10.1182/blood-2025-5872

Published: 2025

Journal Articles

Single-cell transcriptional profiling identifies ADGRG1+ CD8 T cells as critical mediators of graft-versus-leukemia effect in AML relapse after haploidentical hematopoietic stem cell transplantation

Panpan Zhu, Luxin Yang, Yibo Wu, Xiaolin Yuan, Lizhen Liu, Xiaoyu Lai, He Huang, Shanshan Pei, Hezhou Guo, Yi Luo

Blood (2025) 146 (Supplement 1): 5870.

https://doi.org/10.1182/blood-2025-5870

Published: 2025

Journal Articles

Dysregulated lung microbiota impaired hematopoietic stem cell function in mice with pulmonary diseases.

Xiangjun Zeng, Ce Shi, Meng Zhang, Pengxu Qian, He Huang

Blood (2025) 146 (Supplement 1): 4926.

https://doi.org/10.1182/blood-2025-4926

Published: 2025

Journal Articles

Safety and activity of gene therapy with AAV8 GBA1 (LY-M001)on type I adults gaucher disease

Yishan Ye, Xueping Luo, Jingwen Li, Yixiong Chen, Qin Lin, He Huang, Weiyan Zheng

Blood (2025) 146 (Supplement 1): 6098.

https://doi.org/10.1182/blood-2025-6098

Published: 2025

Journal Articles

Thymic dysfunction promotes the emergence of pathogenic peripheral CD4⁺CD8⁺ T cells and induces tissue injury in acute gvhd

Meng Zhang, Hengwei Wu, Xinyi Lai, Xiangjun Zeng, Mengmeng Huang, Yingru Jiang, Yanjuan Liu, Yanmin Zhao, Fang Ye, He Huang

Blood (2025) 146 (Supplement 1): 4240.

https://doi.org/10.1182/blood-2025-4240

Published: 2025

Journal Articles

Aponermin combined with carfilzomid-pomalidomide-dexamethasone (KPd) in patients with relapsed or refractory multiple myeloma: A prospective, open-label, multicenter study

Jing Chen, Donghua He, Xiaoyan Han, Mingming Zhang, Li Yang, Haimeng Yan, Lai Jin, He Huang, Juan Du, Aijun Liu, Zhen Cai

Blood (2025) 146 (Supplement 1): 2276.

https://doi.org/10.1182/blood-2025-2276

Published: 2025

Journal Articles

Metabolomic dynamics of cytokine release syndrome in CD19 CAR-T therapy

Zhouning Lin, Tingting Yang, Mingming Zhang, Shan Fu, Meng Zhang, Zhong Zheng Zheng, He Huang, Yongxian Hu

Blood (2025) 146 (Supplement 1): 7663.

https://doi.org/10.1182/blood-2025-7663

Published: 2025

Journal Articles

High serum C3 complement levels were associated with poor prognosis of angioimmunoblastic T-cell lymphoma (AITL)

Mengmeng Dong, Yi Zhong, Fang Yu, Yi Zhao, Lixia Zhu, Fengping Zhou, Linlin Huang, Xiu-Jin Ye, Zhen Cai, He Huang, Jin Zhang, Baodong Ye, Qingming Wang, Jingsong He

Blood (2025) 146 (Supplement 1): 7158.

https://doi.org/10.1182/blood-2025-7158

Published: 2025

Journal Articles

Adult hemophagocytic lymphohistiocytosis: A multicenter retrospective analysis of etiology and impact on survival in China

Jingsong He, Lixia Zhu, Mengqi Xiong, Jianguo Zhang, Yinyi Zhang, Xin Guo, Linjie Li, Lihong Shou, Qunyi Guo, Shuangwei Ying, Li Li, YI LI, Zhen Cai, He Huang, Xiu-Jin Ye

Blood (2025) 146 (Supplement 1): 6549.

https://doi.org/10.1182/blood-2025-6549

Published: 2025

Journal Articles

Pre-treatment ZNF683⁺ effector CD8⁺ T cells predict response to BiTE therapy in acute lymphoblastic leukemia: Insights from single-cell and TCR sequencing

Linghui Zhou, Cheng Zu, Kexin Wang, Mingming Zhang, Shan Fu, Jingjing Feng, He Huang, Yongxian Hu

Blood (2025) 146 (Supplement 1): 5086.

https://doi.org/10.1182/blood-2025-5086

Published: 2025

Journal Articles

Lamin B1 mediates dynamic changes in heterochromatin and regulates erythropoiesis

Dawei Huo, Rui Wen, Qiqi Zhang, Yiqi Li, He Huang

Blood (2025) 146 (Supplement 1): 2885.

https://doi.org/10.1182/blood-2025-2885

Published: 2025

Journal Articles

Ultra-low-dose IL-10-expressing CAR-T cells achieve high efficacy in R/R DLBCL: An update analysis

Blood (2025) 146 (Supplement 1): 2395.

https://doi.org/10.1182/blood-2025-2395

Published: 2025

Journal Articles

OL-101, a BCMA/GPRC5D dual-targeting autologous CAR-T for relapsed/ refractory multiple myeloma (R/R MM): Results from a Phase I study

Yongxian Hu, Mingming Zhang, Yajing Zhang, Shan Fu, Jingjing Feng, Guoai Su, Dan Song, Chia-Wei Chang, Hongmei Wang, Sihui Guan, He Huang

Blood (2025) 146 (Supplement 1): 2387.

https://doi.org/10.1182/blood-2025-2387

Published: 2025

Journal Articles

Decoding neurotoxicity: A multi-disease single-cell atlas of cerebrospinal fluid reveals conserved and context-specific pathogenic hallmarks

Xia Li, Wanying Zhang, Jiehan Liang, Shaogang Li, Yinnan Tong, Tingfeng Shen, Haikun Lin, Yongxian Hu, Fang Ye, He Huang

Blood (2025) 146 (Supplement 1): 1227.

https://doi.org/10.1182/blood-2025-1227

Published: 2025

Journal Articles

Integrating genomic features for prognosis in Chinese patients with B-cell lymphoma following R-CHOP therapy

Shi Han, Yongxian Hu, He Huang

Blood (2025) 146 (Supplement 1): 3670.

https://doi.org/10.1182/blood-2025-3670

Published: 2025

Journal Articles

Allogeneic hematopoietic cell transplantation in TP53-mutated Acute Myeloid Leukemia patients with active disease: A study from the global committee and the acute leukemia working party of the EBMT

Blood (2025) 146 (Supplement 1): 2523.

https://doi.org/10.1182/blood-2025-2523

Published: 2025

Journal Articles

CTD402, allogeneic anti-CD7 CAR t-cell, in relapsed or refractory (R/R) t-cell acute lymphoblastic leukemia/lymphoblastic lymphoma (T-ALL/LBL) - report of clinical outcomes at the recommended phase 2 dose (RP2D)

Blood (2025) 146 (Supplement 1): 1042.

https://doi.org/10.1182/blood-2025-1042

Published: 2025

Journal Articles

Interim Phase 1 study of sequential CD7 CAR T-cell therapy and haploidentical HSCT without GVHD prophylaxis in patients with Relapsed/Refractory CD7-positive hematologic malignancies

Tingting Yang, Mingming Zhang, Mengqi Yu, Shan Fu, Jingjing Feng, Huijun Xu, Jiazhen Cui, Simao Huang, Guoqing Wei, Alex H. Zhang, He Huang, Yongxian Hu

Blood (2025) 146 (Supplement 1): 1040.

https://doi.org/10.1182/blood-2025-1040

Published: 2025

Journal Articles

Rituximab, lenalidomide, and zanubrutinib (ZR2) with sequential CAR-T cell as first-line therapy for high-risk large B cell lymphoma

Mingming Zhang, Lianxuan Liu, Yongxian Hu, Guoqing Wei, Shan Fu, Jingjing Feng, Ruimin Hong, Alex H. Zhang, He Huang

Blood (2025) 146 (Supplement 1): 1940.

https://doi.org/10.1182/blood-2025-1940

Published: 2025

Journal Articles

Low-dose 10-day decitabine plus venetoclax induced rapid MRD negativity and durable remission in de novo AML and high-risk MDS

Junqing Wu, Xueping Luo, Xiaoyu Liu, Jingwen Li, Shan Fu, He Huang, Weiyan Zheng

Blood (2025) 146 (Supplement 1): 3449.

https://doi.org/10.1182/blood-2025-3449

Published: 2025

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Role of ferroptosis in aGVHD-induced liver tissue damage: Mediation by Acsl4-regulated PUFA-pls

Single-cell transcriptional profiling identifies ADGRG1+ CD8 T cells as critical mediators of graft-versus-leukemia effect in AML relapse after haploidentical hematopoietic stem cell transplantation

Dysregulated lung microbiota impaired hematopoietic stem cell function in mice with pulmonary diseases.

Safety and activity of gene therapy with AAV8 GBA1 (LY-M001)on type I adults gaucher disease

Thymic dysfunction promotes the emergence of pathogenic peripheral CD4⁺CD8⁺ T cells and induces tissue injury in acute gvhd

Aponermin combined with carfilzomid-pomalidomide-dexamethasone (KPd) in patients with relapsed or refractory multiple myeloma: A prospective, open-label, multicenter study

Metabolomic dynamics of cytokine release syndrome in CD19 CAR-T therapy

High serum C3 complement levels were associated with poor prognosis of angioimmunoblastic T-cell lymphoma (AITL)

Adult hemophagocytic lymphohistiocytosis: A multicenter retrospective analysis of etiology and impact on survival in China

Pre-treatment ZNF683⁺ effector CD8⁺ T cells predict response to BiTE therapy in acute lymphoblastic leukemia: Insights from single-cell and TCR sequencing

Lamin B1 mediates dynamic changes in heterochromatin and regulates erythropoiesis

Ultra-low-dose IL-10-expressing CAR-T cells achieve high efficacy in R/R DLBCL: An update analysis

OL-101, a BCMA/GPRC5D dual-targeting autologous CAR-T for relapsed/ refractory multiple myeloma (R/R MM): Results from a Phase I study

Decoding neurotoxicity: A multi-disease single-cell atlas of cerebrospinal fluid reveals conserved and context-specific pathogenic hallmarks

Integrating genomic features for prognosis in Chinese patients with B-cell lymphoma following R-CHOP therapy

Allogeneic hematopoietic cell transplantation in TP53-mutated Acute Myeloid Leukemia patients with active disease: A study from the global committee and the acute leukemia working party of the EBMT

CTD402, allogeneic anti-CD7 CAR t-cell, in relapsed or refractory (R/R) t-cell acute lymphoblastic leukemia/lymphoblastic lymphoma (T-ALL/LBL) - report of clinical outcomes at the recommended phase 2 dose (RP2D)

Interim Phase 1 study of sequential CD7 CAR T-cell therapy and haploidentical HSCT without GVHD prophylaxis in patients with Relapsed/Refractory CD7-positive hematologic malignancies

Rituximab, lenalidomide, and zanubrutinib (ZR2) with sequential CAR-T cell as first-line therapy for high-risk large B cell lymphoma

Low-dose 10-day decitabine plus venetoclax induced rapid MRD negativity and durable remission in de novo AML and high-risk MDS

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