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Journal Articles

A predictive model for therapy failure in patients with chronic myeloid leukemia receiving tyrosine kinase inhibitor therapy

Clinical Trials & Observations
Xiaoshuai Zhang, Bingcheng Liu, Jian Huang, Yanli Zhang, Na Xu, Robert Peter Gale, Weiming Li, Xiaoli Liu, Huanling Zhu, Ling Pan, Yunfan Yang, Hai Lin, Xin Du, Rong Liang, Chunyan Chen, Xiaodong Wang, Guohui Li, Zhuogang Liu, Yanqing Zhang, Zhenfang Liu, Jianda Hu, Chunshui Liu, Fei Li, Wei Yang, Li Meng, Yanqiu Han, Li’e Lin, Zhenyu Zhao, Chuanqing Tu, Caifeng Zheng, Yanliang Bai, Zeping Zhou, Suning Chen, Huiying Qiu, Lijie Yang, Xiuli Sun, Hui Sun, Li Zhou, Zelin Liu, Danyu Wang, Jianxin Guo, Liping Pang, Qingshu Zeng, Xiaohui Suo, Weihua Zhang, Yuanjun Zheng, Xiaojun Huang, Qian Jiang
Journal: Blood
Blood (2024) 144 (18): 1951–1961.
https://doi.org/10.1182/blood.2024024761
Published: 2024
Includes: Supplemental data
Journal Articles

Flumatinib Versus Nilotinib for Newly Diagnosed Chronic Phase Chronic Myeloid Leukemia

Suning Chen, Yanli Zhang, Na Xu, Hui Sun, Li Weiming, Yunfan Yang, Zunmin Zhu, Minghui Duan, Sixuan Qian, Yu Zhu, Jianmin Luo, Xiaodong Wang, Wei Yang, Weiying Gu, Fei Li, Bingcheng Liu, Yunxiao Xu, Zhenfang Liu, Chunling Wang, Yirong Jiang, Li Meng, Qin Wen, Yanli Xu, Xingli Zou, Wei Wang, Yan Xue, Hao Xu, Kehong Bi, Fuling Zhou, Liangming Ma, Rong Fu, Guifang Ouyang, Kaiyang Ding, Depei Wu
Journal: Blood
Blood (2023) 142 (Supplement 1): 1797.
https://doi.org/10.1182/blood-2023-179073
Published: 2023
Journal Articles

A Multicenter, Open-Label, Single-Arm, Phase Ib Clinical Trial of HH2853 in the Treatment of Patients with Relapsed and/or Refractory Peripheral T-Cell Lymphoma

Huangming Hong, Mingzhi Zhang, Zhigang Peng, Jianzhen Shen, Yuerong Shuang, Hui Zhou, Hongqiang Guo, He Huang, Fei Li, Zhengzi Qian, Lihong Liu, Liang Wang, Wei Yang, Liling Zhang, Pengcheng He, Shen Qian, Fugen Li, Meng Li, Tongyu Lin
Journal: Blood
Blood (2023) 142 (Supplement 1): 304.
https://doi.org/10.1182/blood-2023-180372
Published: 2023
Journal Articles

The Modified Melphalan-Cladribine-Busulfan-Cyclophosphamide (MCBC) Conditioning Regimen Improved Relapse-Free Survival after Allo-HSCT in Refractory/Relapsed AML

Xiaoyu Zhang, Shulian Chen, Weihua Zhai, Yi He, Sizhou Feng, Mingzhe Han, Ting Niu, Yajing Xu, Guangxun Gao, Shengjin Fan, Zepin Zhou, Fang Zhou, Rui Xi, Li Liu, Wei Yang, Xi Zhang, Qifa Liu, Erlie Jiang
Journal: Blood
Blood (2023) 142 (Supplement 1): 474.
https://doi.org/10.1182/blood-2023-184477
Published: 2023
Journal Articles

Loncastuximab Tesirine Demonstrated Substantial Single-Agent Efficacy and Manageable Safety Profile in Heavily Pretreated Chinese Patients with Relapsed or Refractory (R/R) Diffuse Large B-Cell Lymphoma (DLBCL)

Ningjing Lin, Xiuhua Sun, Hui Zhou, Liqun Zou, Keshu Zhou, Lihong Liu, Haiyan Yang, Kai HU, Qingqing Cai, Yao Liu, Jie Jin, Liling Zhang, Wenyu Li, Ye Guo, Wei Yang, Feng Luo, Yanyan Li, Mengqi Zhang, Feinan Lu, Yuqin Song, Jun Zhu
Journal: Blood
Blood (2023) 142 (Supplement 1): 4469.
https://doi.org/10.1182/blood-2023-173645
Published: 2023
Journal Articles

Orelabrutinib Monotherapy in Patients with Relapsed or Refractory Waldenström's Macroglobulinemia in a Single-Arm, Multicenter, Open-Label, Phase 2 Study: Long Term Follow-up Results

Xinxin Cao, Jie Jin, Fu Cheng Cheng, Shuhua Yi, Weili Zhao, Zimin Sun, Wei Yang, Dengju Li, Guohui CUI, Jianda Hu, Ting Liu, Yongping Song, Bing Xu, Zunmin Zhu, Wei Xu, Mingzhi Zhang, Sichen Li, Weige Wang, Renbin Zhao, Daobin Zhou
Journal: Blood
Blood (2023) 142 (Supplement 1): 3039.
https://doi.org/10.1182/blood-2023-181500
Published: 2023
Journal Articles

Update Results of a Phase II Trial of Venetoclax in Combination with Azacitidine and Chidamide in Relapsed/Refractory Acute Myeloid Leukemia

Jie Zha, Ying Wang, Zhenling Li, Zhijuan Lin, Yun Cai, Tiejun Gong, Wei Yang, Siting Xie, Zhenqi Huang, Pengcheng SHI, Lin Fu, Jinghua Wang, Xiangjun Fu, Xianqi Feng, Liping Su, Jianmin Luo, Lin Yang, Biyun Chen, Ying Xie, Yu Zhu, Xin Du, Yirong Jiang, Zhifeng Li, Bing Xu
Journal: Blood
Blood (2023) 142 (Supplement 1): 4274.
https://doi.org/10.1182/blood-2023-182832
Published: 2023
Journal Articles

RSK1 Is an Exploitable Dependency in Myeloid Malignancies

Tim Kong, Angelo B. A. Laranjeira, LaYow Yu, Jared Scott Fowles, Daniel A.C. Fisher, Sherwin Ng, Wei Yang, Fan He, Maggie J Cox, Mary C. Fulbright, Stacey L. Rentschler, My-my Huynh, Gerrit Los, Sandra E. Dunn, Grant A Challen, Stephen T. Oh
Journal: Blood
Blood (2023) 142 (Supplement 1): 46.
https://doi.org/10.1182/blood-2023-182320
Published: 2023
Journal Articles

Understanding the Functional Differences between PRC2.1 and PRC2.2 in Hematopoiesis

Hassan Bjeije, Nancy Issa, Wentao Han, Yanan Li, Wei Yang, Jeffrey Magee, Grant A Challen
Journal: Blood
Blood (2023) 142 (Supplement 1): 1311.
https://doi.org/10.1182/blood-2023-184884
Published: 2023
Journal Articles

NUP98 -Rearranged Acute Myeloid Leukemia Stem Cells Superimpose Type I Interferon Signaling with Canonical Self-Renewal Programs

Yanan Li, Wei Yang, Riddhi M. Patel, Emily B. Casey, Elisabeth Denby, Jeffrey Magee
Journal: Blood
Blood (2023) 142 (Supplement 1): 4125.
https://doi.org/10.1182/blood-2023-182032
Published: 2023
Journal Articles

Safety and Efficacy Results from the Phase I Study of a Novel Dual Covalent and Non-Covalent Next Generation Inhibitor of Bruton's Tyrosine Kinase LP-168 in Patients with Relapsed/Refractory Mantle Cell Lymphoma

Yuqin Song, Qingqing Cai, Ming Jiang, Keshu Zhou, Lei Zhang, Xiuhua Sun, Zhengming Jin, Lanfang Li, Hongmei Jing, Zhigang Peng, Haiyan Yang, Junyuan Qi, Hui Zhou, Wei Yang, Min Zhou, Chunyan Ji, Wei Xu, Kaiyang Ding, Li Yu, Zheng Wang, Nawei Liu, Yejiang Lou, Yue Shen, Yi Chen, Fenlai Tan, Jun Zhu
Journal: Blood
Blood (2023) 142 (Supplement 1): 3033.
https://doi.org/10.1182/blood-2023-180694
Published: 2023
Journal Articles

A Novel Dual Covalent and Non-Covalent Next Generation Inhibitor of Bruton's Tyrosine Kinase LP-168 in Patients with Relapsed/Refractory B Cell Non-Hodgkin Lymphoma: Safety and Efficacy Results from a Phase 1 Study

Yuqin Song, Qingqing Cai, Ming Jiang, Keshu Zhou, Lei Zhang, Xiuhua Sun, Zhengming Jin, Lanfang Li, Hongmei Jing, Zhigang Peng, Haiyan Yang, Junyuan Qi, Hui Zhou, Wei Yang, Min Zhou, Chunyan Ji, Wei Xu, Kaiyang Ding, Li Yu, Zheng Wang, Nawei Liu, Yejiang Lou, Yue Shen, Yi Chen, Fenlai Tan, Jun Zhu
Journal: Blood
Blood (2023) 142 (Supplement 1): 4400.
https://doi.org/10.1182/blood-2023-180485
Published: 2023
Journal Articles

Preliminary Results of a Phase 2 Study of IMM01 Combined with Azacitidine (AZA) As the First-Line Treatment in Adult Patients with Chronic Myelomonocytic Leukemia (CMML)

Hongyan Tong, Sujun Gao, Wei Yang, Junmin Li, Qingsong Yin, Xingli Zhao, Xiaojing Yan, Sanfang Tu, Fei Li, Haiping Yang, Ronghua Hu, Shaoyuan Wang, Zheng Dong, Yixuan Yang, Zhenjiu Wang, Qiying Lu, Wenzhi Tian, Zhijian Xiao, Jianxiang Wang
Journal: Blood
Blood (2023) 142 (Supplement 1): 1859.
https://doi.org/10.1182/blood-2023-181501
Published: 2023
Journal Articles

Preliminary Results of a Phase 2 Study of IMM01 Combined with Azacitidine (AZA) As the First-Line Treatment in Adult Patients with Higher Risk Myelodysplastic Syndromes (MDS)

Wei Yang, Sujun Gao, Xiaojing Yan, Rong Guo, Lijie Han, Fei Li, Yafei Wang, Junmin Li, Chunkang Chang, Haiping Yang, Ronghua Hu, Hongyan Tong, Xingli Zhao, Qiubai Li, Jingdong Zhang, Xin Du, Sanfang Tu, Cheng Zhang, Congmeng Lin, Xin Du, Zhenling Li, Ligen Liu, Zhenyu Li, Zheng Dong, Yixuan Yang, Qiying Lu, Wenzhi Tian, Zhijian Xiao
Journal: Blood
Blood (2023) 142 (Supplement 1): 320.
https://doi.org/10.1182/blood-2023-174420
Published: 2023
Journal Articles

Divergent Roles of MLL3 and MLL4 in Hematopoietic Stem Cell Fate Decision

Helen C. Wang, Ran Chen, Wei Yang, Riddhi M. Patel, Emily B. Casey, Elisabeth Denby, Jeffrey Magee
Journal: Blood
Blood (2023) 142 (Supplement 1): 400.
https://doi.org/10.1182/blood-2023-178765
Published: 2023
Journal Articles

Real-World Analysis of Treatment Patterns and the Effectiveness and Safety Profile of Daratumumab-Based Regimens in Chinese Patients with Newly Diagnosed or Relapsed/Refractory Multiple Myeloma

Luqun Wang, Wei Yang, Yafei Wang, Ting Niu, Rong Fu, Yuping Zhong, Wenbin Qian, Kaiyang Ding, Kai Sun, Hong Liu, Baijun Fang, Hui Liu, Yanhui Li, Yishen Yang, Jianmin Zhuo, Xi Chen, Canchan Cui, Jin Lu
Journal: Blood
Blood (2023) 142 (Supplement 1): 6635.
https://doi.org/10.1182/blood-2023-180948
Published: 2023
Journal Articles

FLT3 ITD drives context-specific changes in cell identity and variable interferon dependence during AML initiation

Yanan Li, Wei Yang, Riddhi M. Patel, Emily B. Casey, Elisabeth Denby, Jonny Mendoza-Castrejon, Priscilla Rodriguez-Lopez, Jeffrey A. Magee
Journal: Blood
Blood (2023) 141 (12): 1442–1456.
https://doi.org/10.1182/blood.2022016889
Published: 2023
Includes: Supplemental data
Journal Articles

The tetraspanin CD53 protects stressed hematopoietic stem cells via promotion of DREAM complex–mediated quiescence

Zev J. Greenberg, Luana Chiquetto Paracatu, Darlene A. Monlish, Qian Dong, Michael Rettig, Nate Roundy, Rofaida Gaballa, Weikai Li, Wei Yang, Cliff J. Luke, Laura G. Schuettpelz
Journal: Blood
Blood (2023) 141 (10): 1180–1193.
https://doi.org/10.1182/blood.2022016929
Published: 2023
Includes: Supplemental data
Journal Articles

KMT2C/ MLL3 Attenuates Committed Myeloid Progenitor Self-Renewal Capacity and Balances Granulocyte and Monocyte/Dendritic Cell Output

Helen C. Wang, Ran Chen, Wei Yang, Riddhi M Patel, Emily B Casey, Jeffrey A. Magee
Journal: Blood
Blood (2022) 140 (Supplement 1): 4485–4486.
https://doi.org/10.1182/blood-2022-165717
Published: 2022
Journal Articles

The Efficacy and Safety of Modified Melphalan and Busulfan-Based Conditioning Regimen for Allogeneic-HSCT in Refractory/Relapsed or Persistent MRD Positive AML Patients

Shulian Chen, Xiaoyu Zhang, Weihua Zhai, Yi He, Sizhou Feng, Mingzhe Han, Ting Niu, Yajing Xu, Guangxun Gao, Shengjin Fan, Zeping Zhou, Fang Zhou, Xi Rui, Li Liu, Wei Yang, Qifa Liu, Xi Zhang, Erlie Jiang
Journal: Blood
Blood (2022) 140 (Supplement 1): 10467–10468.
https://doi.org/10.1182/blood-2022-165140
Published: 2022