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Journal Articles

Targeting Covalent and Non-Covalent Btki-Resistant CLL Using the Dual Irreversible/Reversible 4 th Generation BTK Inhibitor LP-168

Britten Gordon, Elizabeth Muhowski, Janani Ravikrishnan, Samon Benrashid, Andrew Mitchell, Alexander He, Shrilekha Misra, Tzung-Huei Lai, Shanmugapriya Thangavadivel, Alexander Marr, Lianbo Yu, Brandi Walker, Elizabeth Perry, Kerry A Rogers, Adam S Kittai, Seema A Bhat, John C. Byrd, Deepa Sampath, Rosa Lapalombella, Weiguo Han, Neil E. Kay, Yi Chen, Fenlai Tan, Stephen P. Anthony, Yu Chen, Jennifer A. Woyach
Journal: Blood
Blood (2023) 142 (Supplement 1): 416.
https://doi.org/10.1182/blood-2023-178259
Published: 2023
Journal Articles

Safety and Efficacy Results from the Phase I Study of a Novel Dual Covalent and Non-Covalent Next Generation Inhibitor of Bruton's Tyrosine Kinase LP-168 in Patients with Relapsed/Refractory Mantle Cell Lymphoma

Yuqin Song, Qingqing Cai, Ming Jiang, Keshu Zhou, Lei Zhang, Xiuhua Sun, Zhengming Jin, Lanfang Li, Hongmei Jing, Zhigang Peng, Haiyan Yang, Junyuan Qi, Hui Zhou, Wei Yang, Min Zhou, Chunyan Ji, Wei Xu, Kaiyang Ding, Li Yu, Zheng Wang, Nawei Liu, Yejiang Lou, Yue Shen, Yi Chen, Fenlai Tan, Jun Zhu
Journal: Blood
Blood (2023) 142 (Supplement 1): 3033.
https://doi.org/10.1182/blood-2023-180694
Published: 2023
Journal Articles

A Novel Dual Covalent and Non-Covalent Next Generation Inhibitor of Bruton's Tyrosine Kinase LP-168 in Patients with Relapsed/Refractory B Cell Non-Hodgkin Lymphoma: Safety and Efficacy Results from a Phase 1 Study

Yuqin Song, Qingqing Cai, Ming Jiang, Keshu Zhou, Lei Zhang, Xiuhua Sun, Zhengming Jin, Lanfang Li, Hongmei Jing, Zhigang Peng, Haiyan Yang, Junyuan Qi, Hui Zhou, Wei Yang, Min Zhou, Chunyan Ji, Wei Xu, Kaiyang Ding, Li Yu, Zheng Wang, Nawei Liu, Yejiang Lou, Yue Shen, Yi Chen, Fenlai Tan, Jun Zhu
Journal: Blood
Blood (2023) 142 (Supplement 1): 4400.
https://doi.org/10.1182/blood-2023-180485
Published: 2023
Journal Articles

Initial Results of a Phase 1 Dose Escalation Study of LP-168, a Novel Covalent and Non-Covalent Next-Generation Inhibitor of Bruton's Tyrosine Kinase

Jennifer A. Woyach, Deborah M. Stephens, Danielle M Brander, Adam S Kittai, Boyu Hu, Andrea Sitlinger, Emily K Curran, Fenlai Tan, Yi Chen, Stephen P. Anthony, Yu Chen, John C. Byrd
Journal: Blood
Blood (2023) 142 (Supplement 1): 328.
https://doi.org/10.1182/blood-2023-186432
Published: 2023
Journal Articles

Pre-Clinical Evaluation of a New-Generation Orally Bioavailable Dual Bcl-2/Bcl-Xl Inhibitor LP-118 in Mantle Cell Lymphoma

Ling-Ling Lee, Cong Zhu, Brianna Feldmeier, Yao Chen, Wenyu Li, Yu Chen, Stephen P. Anthony, Yue Shen, Fenlai Tan, Yi Chen, Bing Dai
Journal: Blood
Blood (2023) 142 (Supplement 1): 3640.
https://doi.org/10.1182/blood-2023-180190
Published: 2023
Journal Articles

Single Arm, Multi-Center, Phase II Study Of Clofarabine In Chinese Pediatric Patients With Refractory Or Relapsed Acute Lymphoblastic Leukemia

Leping Zhang, Xin Du, MD, Yan Li, MD, Zhen Cai, MD, PhD, Kang Yu, MD, Fenlai Tan, MD, PhD, Yi Fang, MD, Xiaojun Huang, MD, Jin Lu, MD
Journal: Blood
Blood (2013) 122 (21): 5016.
https://doi.org/10.1182/blood.V122.21.5016.5016
Published: 2013