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Journal Articles

A Novel Dual Covalent and Non-Covalent Next Generation Inhibitor of Bruton's Tyrosine Kinase LP-168 in Patients with Relapsed/Refractory B Cell Non-Hodgkin Lymphoma: Safety and Efficacy Results from a Phase 1 Study

Yuqin Song, Qingqing Cai, Ming Jiang, Keshu Zhou, Lei Zhang, Xiuhua Sun, Zhengming Jin, Lanfang Li, Hongmei Jing, Zhigang Peng, Haiyan Yang, Junyuan Qi, Hui Zhou, Wei Yang, Min Zhou, Chunyan Ji, Wei Xu, Kaiyang Ding, Li Yu, Zheng Wang, Nawei Liu, Yejiang Lou, Yue Shen, Yi Chen, Fenlai Tan, Jun Zhu
Journal: Blood
Blood (2023) 142 (Supplement 1): 4400.
https://doi.org/10.1182/blood-2023-180485
Published: 2023
Journal Articles

Safety and Efficacy Results from the Phase I Study of a Novel Dual Covalent and Non-Covalent Next Generation Inhibitor of Bruton's Tyrosine Kinase LP-168 in Patients with Relapsed/Refractory Mantle Cell Lymphoma

Yuqin Song, Qingqing Cai, Ming Jiang, Keshu Zhou, Lei Zhang, Xiuhua Sun, Zhengming Jin, Lanfang Li, Hongmei Jing, Zhigang Peng, Haiyan Yang, Junyuan Qi, Hui Zhou, Wei Yang, Min Zhou, Chunyan Ji, Wei Xu, Kaiyang Ding, Li Yu, Zheng Wang, Nawei Liu, Yejiang Lou, Yue Shen, Yi Chen, Fenlai Tan, Jun Zhu
Journal: Blood
Blood (2023) 142 (Supplement 1): 3033.
https://doi.org/10.1182/blood-2023-180694
Published: 2023
Journal Articles

All-Trans-Retinoic Acid Induction Overcomes Immune Evasion through Downregulating Immune Checkpoint Molecules and Inducing a Cytokine Storm Triggered By Overexpression of S100A8/A9 Signaling

Suning Chen, Lijun Wen, Lijuan Gao, Yayun Du, Yi Xu, Qian Wu, Xiaofei Yang, Jinlan Pan, Mingqing Zhu, Dandan Liu, Jiannong Cen, Hongjie Shen, Zhao Zeng, Jingren Zhang, Haohao Lu, Zhibo Zhang, Yusha Guo, Zheng Wang, Tingting Zhang, Xiebing Bao, Qian Wang, Qinrong Wang, Yang Xu, Jianhong Fu, Huiying Qiu, Xiaowen Tang, Yue Han, Miao Miao, Shengli Xue, Ying Wang, Sudan He, Depei Wu
Journal: Blood
Blood (2023) 142 (Supplement 1): 4335.
https://doi.org/10.1182/blood-2023-184432
Published: 2023
Journal Articles

Abnormal DNA Damage Response Suggests Novel Fingerprint of Relapse in Acute Monocytic Leukemia Post Transplantation

Ke Sui, Lijuan Tan, Yukun Feng, Rui Wang, Zheng Wang, Xi Zhang
Journal: Blood
Blood (2022) 140 (Supplement 1): 11500–11501.
https://doi.org/10.1182/blood-2022-169609
Published: 2022
Journal Articles

FGFR1 Fusion Genes Combine with RUNX1 Mutations to Drive Leukemogenesis

Zheng Wang, Lijun Wen, Suning Chen, Depei Wu
Journal: Blood
Blood (2021) 138 (Supplement 1): 4597.
https://doi.org/10.1182/blood-2021-154214
Published: 2021
Journal Articles

Autophagy Collaborates with Ubiquitination to Down-Regulate Oncoprotein E2A/Pbx1 in B Cell Acute Lymphoblastic Leukemia

Suping Zhang, MD PhD, Lin Song, BS, Na Yuan, BS, Weiwei Lin, MS, Yan Cao, BS, Fei Xu, MS, Yixuan Fang, BS, Zheng Wang, BS, Xin Li, BS, Zhijian Wang, MS, Jinyang Cai, MS, Wenli Zhao, MD PhD, Shaoyan Hu, MD PhD, Suning Chen, MD PhD, Xinliang Mao, MD PhD, Jianrong Wang, PhD
Journal: Blood
Blood (2014) 124 (21): 5276.
https://doi.org/10.1182/blood.V124.21.5276.5276
Published: 2014
Journal Articles

Bafilomycin A1 Targets Both Autophagy and Apoptosis Pathways in Pediatric t(1;19) Pre-B Acute Lymphoblastic Leukemia Cells

Na Yuan, BS, Lin Song, BS, Suping Zhang, MD PhD, Weiwei Lin, MS, Yan Cao, BS, Fei Xu, MS, Yixuan Fang, BS, Zheng Wang, BS, Zhijian Wang, MS, Xin Li, BS, Jinyang Cai, MS, Yi Zhang, PhD, Wenli Zhao, MD PhD, Shaoyan Hu, MD PhD, Suning Chen, MD PhD, Xinliang Mao, MD PhD, Jianrong Wang, PhD
Journal: Blood
Blood (2014) 124 (21): 3699.
https://doi.org/10.1182/blood.V124.21.3699.3699
Published: 2014
Journal Articles

LEF-1 Transcription Factor Regulates Proliferation and Differentiation of Myeloid Progenitors in Healthy Individuals and in Patients with Severe Congenital Neutropenia (CN).

Julia Skokowa, MD, PhD, Gunnar Cario, MD, Vesna Bucan, Lan Dan, Zheng Wang, PhD, Michaela Scherr, PhD, Axel Schambach, MD, Cornelia Zeidler, MD, Mathias Eder, MD, Christopher Baum, MD, Martin Stanulla, MD, Karl Welte, MD, PhD
Journal: Blood
Blood (2005) 106 (11): 390.
https://doi.org/10.1182/blood.V106.11.390.390
Published: 2005
Journal Articles

Role of TPO in the Differentiation of Embryonic Stem Cells into Hematopoetic Cells.

Zheng Wang, PhD, Pramono Andri, Skokowa Julia, Ph.D, Welte Karl, MD
Journal: Blood
Blood (2005) 106 (11): 4202.
https://doi.org/10.1182/blood.V106.11.4202.4202
Published: 2005
Journal Articles

Defective Expression of LEF-1 Transcription Factor mRNA and - Protein in Patients with Severe Congenital Neutropenia (Kostmann’S Syndrome).

Julia Skokowa, MD PhD, Gunnar Cario, MD, Zheng Wang, PhD, Cornelia Zeidler, MD, Martin Stanulla, MD, Karl Welte, MD PhD
Journal: Blood
Blood (2004) 104 (11): 782.
https://doi.org/10.1182/blood.V104.11.782.782
Published: 2004
Journal Articles

Administration of Granulocyte Colony-Stimulating Factor Does Not Restore Defective Expression of bcl-2 and bcl-2-xL in Myeloid Progenitor Cells of Patients with Severe Congenital Neutropenia (Kostmann Syndrome).

Gunnar Cario, MD, Julia Skokowa, MD PhD, Zheng Wang, PhD, Vesna Bucan, Cornelia Zeidler, MD, Martin Stanulla, MD, Martin Schrappe, MD PhD, Karl Welte, MD PhD
Journal: Blood
Blood (2004) 104 (11): 1456.
https://doi.org/10.1182/blood.V104.11.1456.1456
Published: 2004
Journal Articles

High-level ectopic HOXB4 expression confers a profound in vivo competitive growth advantage on human cord blood CD34 + cells, but impairs lymphomyeloid differentiation

Bernhard Schiedlmeier, Hannes Klump, Elke Will, Gökhan Arman-Kalcek, Zhixiong Li, Zheng Wang, Andreas Rimek, Jutta Friel, Christopher Baum, Wolfram Ostertag
Journal: Blood
Blood (2003) 101 (5): 1759–1768.
https://doi.org/10.1182/blood-2002-03-0767
Published: 2003