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Journal Articles

A phase I study of HDM2005, a ROR1 targeted antibody-drug conjugate (ADC), in patients with relapsed or refractory B-cell non-Hodgkin lymphoma (B-NHL) or classical Hodgkin lymphoma(cHL)

Free
Shuhua Yi, Liping Su, Bingzong Li, Zhiming Li, Zhengming Jin, Ming Jiang, Wenjuan Yu, Zengjun Li, Jun Luo, Wei Yang, Fei Li, Cailing Wang, Hui Wu, Qiang Wang, Bing Yu, Jianghua Chen, June Xu, Lugui Qiu
Journal: Blood
Blood (2025) 146 (Supplement 1): 1808.
https://doi.org/10.1182/blood-2025-1808
Published: 2025
Journal Articles

Efficacy and safety of rocbrutinib, a highly selective 4th-generation Bruton's tyrosine kinase inhibitor, in relapsed/refractory Mantle Cell Lymphoma (R/R MCL): Updated results from the phase 1 study

Free
Yuqin Song, Qingqing Cai, Keshu Zhou, Zhengming Jin, Ming Jiang, Xiuhua Sun, Lei Zhang, Haiyan Yang, Lanfang Li, Kaiyang Ding, Junyuan Qi, MIN Zhou, Hongmei Jing, Wei Yang, Hui Zhou, Jun Ma, Zhigang Peng, Wei Xu, Yuankai Shi, Guohui Cui, Zheng Wang, Nawei Liu, Yejiang Lou, Yue Shen, Yi Chen, Fenlai Tan, Jun Zhu
Journal: Blood
Blood (2025) 146 (Supplement 1): 3587.
https://doi.org/10.1182/blood-2025-3587
Published: 2025
Journal Articles

Efficacy and safety of rocbrutinib, the fourth generation bruton's tyrosine kinase inhibitor, in patients with BTK inhibitor pre-treated relapsed or refractory Mantle Cell Lymphoma: Results from a Phase II rock-1 trial

Free
Yuqin Song, Qingqing Cai, Xiaoqiong Tang, Keshu Zhou, Lihong Liu, Zhigang Peng, Xiaojing Yan, Kaiyang Ding, Jianzhen Shen, Huijing Wu, Jie Cui, Hui Zhou, Jianqiu Wu, Hongmei Jing, Ming Jiang, Xiuhua Sun, Yu Yang, Kang Yu, Wei Yang, Zhifeng Li, Zhengming Jin, Shuhua Yi, Fei Li, Guowu Wu, Xiaolei Wei, Gaoxiang Wang, Yudan Wu, Ningjing Lin, Fenlai Tan, Yue Shen, Yejiang Lou, Xiang Xiao, Jun Zhu
Journal: Blood
Blood (2025) 146 (Supplement 1): 886.
https://doi.org/10.1182/blood-2025-886
Published: 2025
Journal Articles

Targeting ephrin A3 in the bone marrow niche offers a promising therapeutic strategy to impede hematopoietic stem cell maintenance in MDS patients

Free
Syed Mian, Marie Goulard, Fatihah Mohamad Nor, Jenny Hsiao-Wen Huang, Khadidja Habel, Ming Jiang, Remisha Gurung, Linda Ariza-McNaughton, Miriam Llorian Sopena, Stuart Horswell, Deborah Schneider-Luftman, Manuel Garcia Albornoz, Karlok Kong, Kevin rouault-Pierre, Catherine Cargo, Matteo Della Porta, Michaela Fontenay, Pierre Fenaux, Christine Dosquet, Ghulam Mufti, Dominique Bonnet
Journal: Blood
Blood (2025) 146 (Supplement 1): 859.
https://doi.org/10.1182/blood-2025-859
Published: 2025
Journal Articles

EB2023 primes mitochondria for BCL2 dependence and induces pyroptotic cell death via AMPK signaling and the unfolded protein response

Free
Matthew Villaume, Michael Davidson, Anna Skwarska, Maria Arrate, Liana Valin, Sovira Chaudhry, Benjamin Reisman, Ming Jiang, Andrew Monteith, Haley Ramsey, Sarah Olmstead, Agnieszka Gorska, Brent Ferrell, Brian Bachmann, Marina Konopleva, Michael Savona
Journal: Blood
Blood (2025) 146 (Supplement 1): 637.
https://doi.org/10.1182/blood-2025-637
Published: 2025
Journal Articles

Efficacy and safety of rocbrutinib, a highly selective 4th-generation BTK inhibitor, in Chinese patients with chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL)

Free
Yuqin Song, Qingqing Cai, Keshu Zhou, Zhengming Jin, Ming Jiang, Xiuhua Sun, Lei Zhang, Haiyan Yang, Lanfang Li, Kaiyang Ding, Junyuan Qi, MIN Zhou, Hongmei Jing, Wei Yang, Hui Zhou, Jun Ma, Zhigang Peng, Wei Xu, Li Yu, Yuankai Shi, Guohui Cui, Zheng Wang, Nawei Liu, Yejiang Lou, Yue Shen, Yi Chen, Fenlai Tan, Jun Zhu
Journal: Blood
Blood (2025) 146 (Supplement 1): 3896.
https://doi.org/10.1182/blood-2025-3896
Published: 2025
Journal Articles

Polatuzumab vedotin plus R-CHP demonstrates high efficacy with manageable toxicity in treatment-Naïve dual-expressor DLBCL (DEL): Real-world analysis with focus on elderly high-risk patients

Free
Kexing Ren, Liqun Zou, Xi Chen, Ming Jiang, Tian Fang, Li Xie, Beibei Yang, Tao Hai, Chunli Yang, Mo Chen, Yafei Pi
Journal: Blood
Blood (2025) 146 (Supplement 1): 3698.
https://doi.org/10.1182/blood-2025-3698
Published: 2025
Journal Articles

Efficacy and safety of mitoxantrone hydrochloride liposome in peripheral T-cell lymphoma: A multicenter, non-interventional, ambispective cohort real-world study

Free
Donglu Zhao, Huiqiang Huang, Zhiming Li, Lihong Liu, Quande Lin, Jun Fang, Kaiyang Ding, Jie Jin, Yanhong Tong, Dengju Li, Zengjun Li, Liping Su, Liang Wang, Wenbin Qian, Xiuhua Sun, Xiaobo Wang, Pengcheng He, Wei Yang, Jinhai Ren, Liling Zhang, Zunmin Zhu, Lugui Qiu, Dehui Zou, Wei LIU, Hui Zhou, Dongfeng Luo, Xiaojing Yan, Zhenqian Huang, Lintao Bi, Rong FU, Yunhong Huang, Aichun Liu, Xi Zhang, Yao Liu, Hao Zhang, Guangxun Gao, Liangquan Geng, Jingbo Wang, Jia Li, Yi Wang, Liqun Zou, Ming Jiang, Jian Ge, Xiu Li Sun, Yanli Yang, Hongmei Jing, Kai Hu, Zhimin Yan, Shuangnian Xu, Xiangxiang Zhou, Ganggang Wang, Zhilin Gao, Li Liang, Hongfeng Ge, Qingshan Li, Zhixue Zhang, Wuping Li, Xiaojing Xing, Fengzi Wang, Dongping Huang, Jun Qian, Hua Fan, Chanjuan Shen, Jun Ma
Journal: Blood
Blood (2025) 146 (Supplement 1): 1878.
https://doi.org/10.1182/blood-2025-1878
Published: 2025
Journal Articles

Glofitamab-based combinatorial therapy demonstrates high efficacy in primary refractory and early relapsed DLBCL: Real-world evidence of durable responses and immune modulation in high-risk subgroups

Free
Kexing Ren, Liqun Zou, Beibei Yang, Ming Jiang, Xi Chen, Li Xie, Chunli Yang, Tao Hai, Mo Chen, Tian Fang, Yafei Pi
Journal: Blood
Blood (2025) 146 (Supplement 1): 7255.
https://doi.org/10.1182/blood-2025-7255
Published: 2025
Journal Articles

Real-world evidence of improved survival with pola-based regimen in newly diagnosed DLBCL patients with extranodal involvement

Free
Xi Chen, Kexing Ren, Ming Jiang, Liqun Zou
Journal: Blood
Blood (2025) 146 (Supplement 1): 5472.
https://doi.org/10.1182/blood-2025-5472
Published: 2025
Journal Articles

Linperlisib Combined with CHOP Regimen Followed By Autologous Hematopoietic Stem Cell Transplantation and Linperlisib Monotherapy Maintenance for Newly Diagnosed Nodal T-Follicular Helper Cell Lymphoma Patients: A Phase II Trial

Free
Weiping Liu, Yao Liu, Zengjun Li, Shujuan Wen, Zhihua Zhang, Liqun Zou, Ming Jiang, Liping Dou, Ou Bai, Jie Yu, Yue Wang, Jie Chen, Yuqin Song, Jun Zhu
Journal: Blood
Blood (2024) 144 (Supplement 1): 6389.
https://doi.org/10.1182/blood-2024-199929
Published: 2024
Journal Articles

Safety and Efficacy of Rocbrutinib in Patients with Relapsed/Refractory Marginal Zone Lymphoma

Free
Yuqin Song, Qingqing Cai, Keshu Zhou, Ming Jiang, Zhengming Jin, Lei Zhang, Xiuhua Sun, Haiyan Yang, Lanfang Li, Kaiyang Ding, Junyuan Qi, Hongmei Jing, Wei Yang, Min Zhou, Jun Ma, Zhigang Peng, Wei Xu, Hui Zhou, Li Yu, Yuankai Shi, Guohui Cui, Zheng Wang, Nawei Liu, Yejiang Lou, Yue Shen, Yi Chen, Fenlai Tan, Jun Zhu
Journal: Blood
Blood (2024) 144 (Supplement 1): 1635.
https://doi.org/10.1182/blood-2024-194572
Published: 2024
Journal Articles

Improving Targeted Therapies in Primary CNS Lymphoma: Real-World Use of Cerebrospinal Fluid Circulating Tumor DNA for Monitoring

Free
Ming Jiang, Liqun Zou, Lijie Liang, Yingze Liu, Na Li, You Feng
Journal: Blood
Blood (2024) 144 (Supplement 1): 1694.
https://doi.org/10.1182/blood-2024-204947
Published: 2024
Journal Articles

A Phase II Study to Evaluate the Efficacy and Safety of Pimicotinib (ABSK021) in Chronic Graft Versus Host Disease (cGvHD) after 1 or More Lines of Systemic Treatment

Free
Xiaodong Mo, He Huang, Feng Chen, Yi Luo, Jia Chen, Erlie Jiang, Yicheng Zhang, Linghui Xia, Chengwei Luo Luo, Xinchuan Chen, Nainong Li, Ming Jiang, Sujun Gao, Dongqin Yang, Qingli Zuo, Yimin Chen, Li Yao, Pan Liang, Depei Wu
Journal: Blood
Blood (2024) 144 (Supplement 1): 99.
https://doi.org/10.1182/blood-2024-193191
Published: 2024
Journal Articles

Comparison of Outcomes between Haploidentical and Matched Related Donors for Chronic Myelomonocytic Leukemia: A Multicenter Real-World Study

Free
Yuqian Sun, Lixin Wu, Yicheng Zhang, Ya-Jing Xu, Xiaobing Huang, Baodong Ye, Hailong Yuan, Jianying Zhou, Sujun Gao, Fang Zhou, Yue Liu, Xianmin Song, Yu Cai, Xiaoliang Liu, Yi Luo, Luxin Yang, Jianmin Yang, Libing Wang, Yuhua Li, Rui Huang, Shunqing Wang, Ming Zhou, Yujun Dong, Qian Wang, Yimei Feng, Xin Du, Wei Ling, Han Zhu, Zunmin Zhu, Xiangli Chen, Shiyun Wang, Fankai Meng, Kehong Bi, Ning Huang, Ming Jiang, Ting Niu, Jie Ji, Dingming Wan, Bian Zhilei, Yi Chen, Li Liu, Xueqian Yan, Xi Yang, Hai Yi, Xudong Wei, Xin Li, Qian Cheng, Chenglu Yuan, Wen Wang, Yuhong Zhou, Yu-Hong Chen, Fengrong WANG, YuanYuan Zhang, Zhi-Dong Wang, Xiao-Dong Mo, Wei Han, Jing-Zhi Wang, Yu Wang, Huan Chen, Xiangyu Zhao, Ying-jun Chang, Kaiyan Liu, Jia Feng, LanPing Xu, Hongyu Zhang, Xi Zhang, Xiaojun Huang, Xiaohui Zhang
Journal: Blood
Blood (2024) 144 (Supplement 1): 2187.
https://doi.org/10.1182/blood-2024-206919
Published: 2024
Journal Articles

Rocbrutinib, a New-Generation BTK Inhibitor, Demonstrates Safety and Efficacy in Relapsed/Refractory Non-GCB Diffuse Large B Cell Lymphoma

Free
Yuqin Song, Qingqing Cai, Keshu Zhou, Ming Jiang, Zhengming Jin, Lei Zhang, Xiuhua Sun, Haiyan Yang, Lanfang Li, Kaiyang Ding, Junyuan Qi, Hongmei Jing, Wei Yang, Min Zhou, Jun Ma, Zhigang Peng, Wei Xu, Hui Zhou, Li Yu, Yuankai Shi, Guohui Cui, Zheng Wang, Nawei Liu, Yejiang Lou, Yue Shen, Yi Chen, Fenlai Tan, Jun Zhu
Journal: Blood
Blood (2024) 144 (Supplement 1): 3119.
https://doi.org/10.1182/blood-2024-194561
Published: 2024
Journal Articles

Reduction of Radiotherapy Intensity after Achieving Complete Remission with Induction Chemotherapy in Newly Diagnosed Stage I/II Extranodal NK/T-Cell Lymphoma: A Prospective Study

Free
Xi Chen, Li Xie, Ming Jiang, Liqun Zou
Journal: Blood
Blood (2024) 144 (Supplement 1): 3062.
https://doi.org/10.1182/blood-2024-201965
Published: 2024
Journal Articles

Phase 1/2 Studies of DZD8586, a Non-Covalent BBB Penetrant LYN/BTK Dual Inhibitor, in BTK Inhibitor Resistant Chronic Lymphocytic Leukemia (CLL) and Other B-Cell Non-Hodgkin Lymphoma (B-NHL)

Free
Yuqin Song, Keshu Zhou, Hongmei Jing, Geoffrey Chong, Jianqiu Wu, Wei Liu, Zengjun Li, Ming Jiang, Mei Lan, Kaiyang Ding, Guohui CUI, Tingyu Wang, Xutao Guo, Sujun Gao, Constantine S. Tam, Haiyan Yang, Fang Zhu, Wei Yang, Jian-Qing Mi, Liping Su, Ke Fang, Ziyi Liu, Lindsey Roeker, Chan Y. Cheah, Jianyong Li, Lu-Gui Qiu
Journal: Blood
Blood (2024) 144 (Supplement 1): 3248.
https://doi.org/10.1182/blood-2024-197877
Published: 2024
Journal Articles

Safety and Efficacy Results from the Phase I Study of a Novel Dual Covalent and Non-Covalent Next Generation Inhibitor of Bruton's Tyrosine Kinase LP-168 in Patients with Relapsed/Refractory Mantle Cell Lymphoma

Free
Yuqin Song, Qingqing Cai, Ming Jiang, Keshu Zhou, Lei Zhang, Xiuhua Sun, Zhengming Jin, Lanfang Li, Hongmei Jing, Zhigang Peng, Haiyan Yang, Junyuan Qi, Hui Zhou, Wei Yang, Min Zhou, Chunyan Ji, Wei Xu, Kaiyang Ding, Li Yu, Zheng Wang, Nawei Liu, Yejiang Lou, Yue Shen, Yi Chen, Fenlai Tan, Jun Zhu
Journal: Blood
Blood (2023) 142 (Supplement 1): 3033.
https://doi.org/10.1182/blood-2023-180694
Published: 2023
Journal Articles

A Novel Dual Covalent and Non-Covalent Next Generation Inhibitor of Bruton's Tyrosine Kinase LP-168 in Patients with Relapsed/Refractory B Cell Non-Hodgkin Lymphoma: Safety and Efficacy Results from a Phase 1 Study

Free
Yuqin Song, Qingqing Cai, Ming Jiang, Keshu Zhou, Lei Zhang, Xiuhua Sun, Zhengming Jin, Lanfang Li, Hongmei Jing, Zhigang Peng, Haiyan Yang, Junyuan Qi, Hui Zhou, Wei Yang, Min Zhou, Chunyan Ji, Wei Xu, Kaiyang Ding, Li Yu, Zheng Wang, Nawei Liu, Yejiang Lou, Yue Shen, Yi Chen, Fenlai Tan, Jun Zhu
Journal: Blood
Blood (2023) 142 (Supplement 1): 4400.
https://doi.org/10.1182/blood-2023-180485
Published: 2023