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Nicole R. Grieselhuber
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Journal Articles

A Phase 1b/2 Trial of Liposomal Cytarabine and Daunorubicin (CPX-351) in Intermediate to High-Risk Acute Myeloid Leukemia for Patients Who Have Failed an Initial Cycle of Induction Chemotherapy

Corbin Pontious, Ramiro Garzon, James S. Blachly, Bradley Wayne Blaser, Hannah Choe, Nicole R. Grieselhuber, Meixiao Long, Sumithira Vasu, Sarah A Wall, Karilyn T. Larkin, Ann-Kathrin Eisfeld, Kristin L Koenig, Kieran D Sahasrabudhe, Gabriela Sanchez-Petitto, Ayman Saad, Bhavana Bhatnagar, Justin Lyberger, Uma M. Borate, Alice Mims, Brian A. Jonas, Gregory K Behbehani
Journal: Blood
Blood (2023) 142 (Supplement 1): 5946.
https://doi.org/10.1182/blood-2023-184344
Published: 2023
Journal Articles

The PKC-β Inhibitor MS-553 Displays Preclinical Efficacy in BTK Inhibitor Resistant Chronic Lymphocytic Leukemia

Britten Gordon, Elizabeth Muhowski, Janani Ravikrishnan, Shanmugapriya Thangavadivel, Samon Benrashid, Alexander He, Shrilekha Misra, Tzung-Huei Lai, Alexander Marr, Lianbo Yu, Brandi Walker, Elizabeth Perry, Nicole R. Grieselhuber, Kerry A Rogers, James S. Blachly, Adam S Kittai, Seema A Bhat, John C. Byrd, Michael Niesman, Kai Zhang, Deepa Sampath, Jennifer A. Woyach
Journal: Blood
Blood (2023) 142 (Supplement 1): 2260.
https://doi.org/10.1182/blood-2023-182024
Published: 2023
Journal Articles

Brd4 Inhibition Abrogates Inflammation and Self-Renewal in a Murine Model of Tet2 Mutated Clonal Hematopoiesis

Alexander Marr, Madeline Halpin, Dominique Corbin, Britten Gordon, Samon Benrashid, Ethan C. Whipp, Mehdi Gharghabi, Jean Truxall, Olivia Cahn, Kristin L Koenig, Karilyn T. Larkin, Jennifer A. Woyach, Rosa Lapalombella, Nicole R. Grieselhuber
Journal: Blood
Blood (2023) 142 (Supplement 1): 4070.
https://doi.org/10.1182/blood-2023-179237
Published: 2023
Journal Articles

The Novel BET Inhibitor PLX51107 Has In Vitro and In Vivo Activity Against Acute Myeloid Leukemia

Nicole R. Grieselhuber, MD PhD, Shaneice R. Mitchell, BS, Shelley Orwick, BS, Bonnie K. Harrington, DVM, Virginia M. Goettl, DVM, PhD, Alison R. Walker, MD MPH, Bhavana Bhatnagar, DO, Alice S. Mims, MD MSCR, Rebecca B. Klisovic, MD, Sumithra Vasu, MBBS, William Blum, MD, James S. Blachly, MD, David M. Lucas, PhD, Ramiro Garzon, MD, Rosa Lapalombella, PhD, John C. Byrd, MD
Journal: Blood
Blood (2016) 128 (22): 3941.
https://doi.org/10.1182/blood.V128.22.3941.3941
Published: 2016
Journal Articles

Trametinib for the Treatment of IGHV4-34, MAP2K1 Mutant Variant Hairy Cell Leukemia

Leslie A. Andritsos, MD, Mirela Anghelina, MD, Nicole R. Grieselhuber, MD PhD, Sameek Roychowdhury, MD PhD, Julie Reeser, PhD, Cynthia Timmers, PhD, Aharon G. Freud, MD PhD, James S. Blachly, MD, David M. Lucas, PhD, Gerard Lozanski, MD, Jeffrey Jones, MD MPH, Kerry A. Rogers, MD, Weiqiang Zhao, MD PhD, Michael R. Grever, MD
Journal: Blood
Blood (2016) 128 (22): 5598.
https://doi.org/10.1182/blood.V128.22.5598.5598
Published: 2016
Journal Articles

Activation of Notch Signaling Is An Early Event in the Development of PML-Rara -Induced Acute Promyelocytic Leukemia (APL)

Nicole R. Grieselhuber, Jeffery M. Klco, MD, Angela M. Verdoni, Timothy J Ley, MD
Journal: Blood
Blood (2011) 118 (21): 2468.
https://doi.org/10.1182/blood.V118.21.2468.2468
Published: 2011
Journal Articles

A protease-resistant PML-RARα has increased leukemogenic potential in a murine model of acute promyelocytic leukemia

Geoffrey L. Uy, Andrew A. Lane, John S. Welch, Nicole R. Grieselhuber, Jacqueline E. Payton, Timothy J. Ley
Journal: Blood
Blood (2010) 116 (18): 3604–3610.
https://doi.org/10.1182/blood-2008-11-189282
Published: 2010
Includes: Supplemental data
Journal Articles

Chromatin Immunoprecipitation of GFP-Tagged PML-Rara Coupled to High-Throughput Next Generation Sequencing.

Nicole R. Grieselhuber, Jahangheer S. Shaik, PhD, Li-Wei Chang, PhD, Sean McGrath, Lukas D. Wartman, MD, Rakesh Nagarajan, MD, PhD, Richard K. Wilson, PhD, Elaine Mardis, PhD, Timothy J. Ley, MD
Journal: Blood
Blood (2009) 114 (22): 1276.
https://doi.org/10.1182/blood.V114.22.1276.1276
Published: 2009
Journal Articles

The Expression Signature of M3 AML Suggests Direct and Indirect Effects of PML-RARA on Target Genes.

Jacqueline E. Payton, MD, PhD, Nicole R. Grieselhuber, BS, Li-Wei Chang, PhD, Mark A. Murakami, MS, Wenlin Yuan, PhD, Daniel C. Link, MD, Rakesh Nagarajan, MD, PhD, Mark A. Watson, MD, PhD, Timothy J. Ley, MD
Journal: Blood
Blood (2007) 110 (11): 719.
https://doi.org/10.1182/blood.V110.11.719.719
Published: 2007
Journal Articles

Identification of PML-RARa Target Genes Using Microarray and ChIP-on-Chip Analysis.

Wenlin Yuan, PhD, Nicole R. Grieselhuber, BS, Roland D. Green, Timothy J. Ley, MD
Journal: Blood
Blood (2005) 106 (11): 2994.
https://doi.org/10.1182/blood.V106.11.2994.2994
Published: 2005