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Geoffrey L. Uy
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Journal Articles

Itacitinib for Prevention of Graft-Versus-Host Disease and Cytokine Release Syndrome in Haploidentical Transplantation

Clinical Trials & Observations
Ramzi Abboud, Mark A. Schroeder, Michael P Rettig, Reyka G Jayasinghe, Feng Gao, Jeremy Eisele, Leah Gehrs, Julie K. Ritchey, Jaebok Choi, Camille N Abboud, Iskra Pusic, Meagan A Jacoby, Peter Westervelt, Matthew Christopher, Amanda F. Cashen, Armin Ghobadi, Keith Stockerl-Goldstein, Geoffrey L Uy, John F. DiPersio
Journal: Blood
Blood blood.2024026497.
https://doi.org/10.1182/blood.2024026497
Published: 2024
Includes: Supplemental data
Journal Articles

Determining treatment tolerance and fitness for intensive chemotherapy in older adults with AML: a call to action

Vijaya Raj Bhatt, Geoffrey L. Uy, Heidi D. Klepin
Journal: Blood
Blood (2024) 143 (6): 483–487.
https://doi.org/10.1182/blood.2023022611
Published: 2024
Includes: Supplemental data
Journal Articles

Validation of the Molecular International Prognostic Scoring System (IPSS-M) in Patients (Pts) with Myelodysplastic Syndromes/Neoplasms (MDS) Who Underwent Allogenic Stem Cell Transplantation (HSCT)

Tariq Kewan, Jan Philipp Bewersdorf, Ondrej Blaha, Maximilian Stahl, Najla H Al Ali, Amy E. DeZern, Mikkael A. Sekeres, Geoffrey L Uy, Hetty E. Carraway, Pinkal Desai, Elizabeth A. Griffiths, Eytan M. Stein, Andrew M. Brunner, Maria L Amaya, Joshua F. Zeidner, Michael R. Savona, Jessica M. Stempel, Namrata Sonia Chandhok, Constantine Logothetis, Hunter Cochran, Ameera Rose, Gail J. Roboz, Eunice S. Wang, Benjamin Rolles, Amyah C. Harris, Rory M. Shallis, Zhuoer Xie, Eric Padron, Jaroslaw P. Maciejewski, David A Sallman, Matteo Giovanni Della Porta, Rami S. Komrokji, Amer M. Zeidan
Journal: Blood
Blood (2023) 142 (Supplement 1): 4980.
https://doi.org/10.1182/blood-2023-186578
Published: 2023
Journal Articles

Ubtf- Tandem Duplications Are Recurrent Somatic Genetic Events in Adult AML and Associate with Additional Structural Variants and a Distinct Gene Expression Profile (Alliance)

Emily K Curran, Deedra Nicolet, Alejandro Otero-Bravo, Krzysztof Mrózek, Ben Kelly, Christopher J. Walker, Jill Buss, Andrea Laganson, Yazan Abu-Shihab, Alice Mims, William Blum, Jonathan E Kolitz, Bayard L Powell, Geoffrey L Uy, Wendy Stock, Richard M Stone, Andrew J Carroll, John C. Byrd, Elaine R Mardis, Ann-Kathrin Eisfeld
Journal: Blood
Blood (2023) 142 (Supplement 1): 4312.
https://doi.org/10.1182/blood-2023-186722
Published: 2023
Journal Articles

Impact of Type of Hypomethylating Agent (HMA) Used on Outcomes of Patients (Pts) with Higher-Risk Myelodysplastic Syndromes/Neoplasms (HR-MDS) - a Large, Multicenter, Retrospective Analysis

Jan Philipp Bewersdorf, Tariq Kewan, Ondrej Blaha, Maximilian Stahl, Najla H Al Ali, Amy E. DeZern, Mikkael A. Sekeres, Geoffrey L Uy, Hetty E. Carraway, Pinkal Desai, Elizabeth A. Griffiths, Eytan M. Stein, Andrew M. Brunner, Christine M. McMahon, Joshua F. Zeidner, Michael R. Savona, Jessica M. Stempel, Namrata Sonia Chandhok, Rahul Ramaswamy, Gail J. Roboz, Benjamin Rolles, Eunice S. Wang, Amyah C. Harris, Maria L Amaya, Hayley Hawkins, Justin Grenet, Carmelo Gurnari, Rory M. Shallis, Zhuoer Xie, Jaroslaw P. Maciejewski, David A Sallman, Matteo Giovanni Della Porta, Rami S. Komrokji, Amer M. Zeidan
Journal: Blood
Blood (2023) 142 (Supplement 1): 4613.
https://doi.org/10.1182/blood-2023-178728
Published: 2023
Journal Articles

Assessment of Outcomes of Consolidation Therapy By Number of Cycles of Blinatumomab Received in Newly Diagnosed Measurable Residual Disease Negative Patients with B-Lineage Acute Lymphoblastic Leukemia: In the ECOG-ACRIN E1910 Randomized Phase III National Clinical Trials Network Trial

Selina M Luger, Zhuoxin Sun, Ryan J Mattison, Elisabeth Paietta, Kathryn G. Roberts, Yanming Zhang, Janis Racevckis, Hillard M. Lazarus, Jacob M. Rowe, Daniel A. Arber, Matthew J. Wieduwilt, Michaela Liedtke, Julie Bergeron, Brent L. Wood, Yaqi Zhao, Gang Wu, Ti-Cheng Chang, Wenchao Zhang, Keith W Pratz, Shira N. Dinner, Noelle V. Frey, Steven D. Gore, Bhavana Bhatnagar, Ehab L. Atallah, Geoffrey L Uy, Deepa Jeyakumar, Tara L Lin, Cheryl L. Willman, Daniel J. DeAngelo, Elad Sharon, Richard F. Little, Harry P. Erba, Richard M Stone, Charles G. Mullighan, Mark R. Litzow, Martin S. Tallman
Journal: Blood
Blood (2023) 142 (Supplement 1): 2877.
https://doi.org/10.1182/blood-2023-189648
Published: 2023
Journal Articles

Post-Hoc Analysis of Measurable Residual Disease from BMT-CTN 1506/Morpho: FLT3-ITD Variant Allele Frequency and Survival Are Highly Correlated

Mark J. Levis, Mehdi Hamadani, Brent R. Logan, Richard J. Jones, Anurag K. Singh, Mark R. Litzow, John R. Wingard, Esperanza B. Papadopoulos, Alexander Perl, Robert J. Soiffer, Celalettin Ustun, Masumi Ueda Oshima, Geoffrey L Uy, Edmund K. Waller, Sumithira Vasu, Melhem M. Solh, Asmita Mishra, Lori S. Muffly, Hee-Je Kim, Matthias Stelljes, Yuho Najima, Masahiro Onozawa, Kirsty Thomson, Arnon Nagler, Andrew H. Wei, Guido Marcucci, Nahla Hasabou, Mathew Rosales, Jason Hill, Stanley C. Gill, Rishita Nuthethi, Denise King, Heather Wittsack, Adam Mendizabel, Steven M. Devine, Mary M. Horowitz, Yi-Bin Chen
Journal: Blood
Blood (2023) 142 (Supplement 1): 973.
https://doi.org/10.1182/blood-2023-177929
Published: 2023
Journal Articles

Duvelisib for Cytokine Release Syndrome Prophylaxis during CD19-Targeted CAR T Cell Therapy

Michael Slade, Michael P. Rettig, Zachary David Crees, Neha Mehta-Shah, Todd A Fehniger, Amanda F Cashen, Iskra Pusic, Geoffrey L Uy, Peter Westervelt, John DiPersio, Armin Ghobadi
Journal: Blood
Blood (2023) 142 (Supplement 1): 3470.
https://doi.org/10.1182/blood-2023-172439
Published: 2023
Journal Articles

Assessment of T-Cell Receptor (TCR) Mediated T-Cell Activation in Acute Myeloid Leukemia at Diagnosis Has Implications for Risk Stratification and Response to Immune Checkpoint Inhibitors

Nancy BJ Arthur, Agata Gruszczynska, Ma Xenia G Illagan, Michael Prinsen, Sharon E Heath, Tasha Burton, Victoria Donaldson, Cara Lunn Shirai, Eric J. Duncavage, Amanda F Cashen, Geoffrey L Uy, David H Spencer, Stephen M Sykes, Timothy J Ley, Francesca Ferraro
Journal: Blood
Blood (2023) 142 (Supplement 1): 2928.
https://doi.org/10.1182/blood-2023-189573
Published: 2023
Journal Articles

Characterization of Comparative Clinical Outcomes and Molecular Features of Black Patients with Acute Promyelocytic Leukemia (APL) Reveals Similar Survival and Distinct Genomic Profiles

Alma Habib, Isaiah Boateng, Deedra Nicolet, Krzysztof Mrózek, James L Fisher, Allyson Waller, Andrew Stiff, Jill Buss, Andrea Laganson, Sienna Martinez Corzine, Ethan Hamp, Yazan Abu-Shihab, Bayard L Powell, Geoffrey L Uy, Wendy Stock, Richard M Stone, Jonathan E Kolitz, Eunice S. Wang, Andrew J Carroll, Jeffrey W Tyner, Andrew Hantel, Electra D Paskett, John C. Byrd, Elaine R Mardis, Jesse J Plascak, Ann-Kathrin Eisfeld
Journal: Blood
Blood (2023) 142 (Supplement 1): 389.
https://doi.org/10.1182/blood-2023-182376
Published: 2023
Journal Articles

The Ancestry-Related Landscape of Long Non-Coding RNAs (LncRNAs) in Acute Myeloid Leukemia (AML) and Its Impact on Patient (Pt) Survival

Yazan Abu-Shihab, Deedra Nicolet, Krzysztof Mrózek, Andrew Stiff, Christopher J. Walker, Jill Buss, Alice Mims, Christopher C. Oakes, Karilyn T. Larkin, James S. Blachly, Andrew J Carroll, William Blum, Bayard L Powell, Jonathan E Kolitz, Richard M Stone, Geoffrey L Uy, Wendy Stock, Jennifer A. Woyach, John C. Byrd, Dimitrios Papaioannou, Ann-Kathrin Eisfeld, Kellie Archer
Journal: Blood
Blood (2023) 142 (Supplement 1): 722.
https://doi.org/10.1182/blood-2023-185030
Published: 2023
Journal Articles

Validation of the Composite Complete Response (cCR) Definitions in the International Working Group (IWG) 2023 Criteria in Patients (Pts) with Higher-Risk Myelodysplastic Syndromes/Neoplasms (HR-MDS) Treated with Hypomethylating Agents (HMA) - a Large, Multicenter, Retrospective Analysis from the Validate Database

Jan Philipp Bewersdorf, Tariq Kewan, Ondrej Blaha, Maximilian Stahl, Najla H Al Ali, Amy E. DeZern, Mikkael A. Sekeres, Geoffrey L Uy, Hetty E. Carraway, Pinkal Desai, Elizabeth A. Griffiths, Eytan M. Stein, Andrew M. Brunner, Christine M. McMahon, Joshua F. Zeidner, Michael R. Savona, Jessica M. Stempel, Namrata Sonia Chandhok, Constantine Logothetis, Gail J. Roboz, Benjamin Rolles, Eunice S. Wang, Amyah C. Harris, Maria L Amaya, Hayley Hawkins, Justin Grenet, Rory M. Shallis, Zhuoer Xie, Jaroslaw P. Maciejewski, David A Sallman, Matteo Giovanni Della Porta, Rami S. Komrokji, Amer M. Zeidan
Journal: Blood
Blood (2023) 142 (Supplement 1): 324.
https://doi.org/10.1182/blood-2023-180299
Published: 2023
Journal Articles

BRAF -Mutated Acute Myeloid Leukemia (AML) Represents a Distinct, Prognostically Poor Subgroup Enriched in Myelodysplasia-Related (MR-)AML

Yazan Abu-Shihab, Deedra Nicolet, Krzysztof Mrózek, Mark Routbort, Keyur P. Patel, Christopher J. Walker, Jill Buss, Andrew Stiff, Andrea Laganson, Courtney D. DiNardo, Naval Daver, Tapan M. Kadia, Gautam Borthakur, Farhad Ravandi, Andrew J Carroll, Jonathan E Kolitz, Bayard L Powell, William Blum, Maria R. Baer, Guido Marcucci, Geoffrey L Uy, Wendy Stock, Richard M Stone, L. Jeffrey Medeiros, Robert L. Bowman, John C. Byrd, James S. Blachly, Linde A. Miles, Ann-Kathrin Eisfeld, Sanam Loghavi
Journal: Blood
Blood (2023) 142 (Supplement 1): 1575.
https://doi.org/10.1182/blood-2023-185135
Published: 2023
Journal Articles

Itacitinib for Prevention of Graft-Versus-Host Disease and Cytokine Release Syndrome with T-Cell Replete Peripheral Blood Haploidentical Transplantation

Ramzi Abboud, Mark A. Schroeder, Michael P. Rettig, Feng Gao, Julie K. Ritchey, Camille N. Abboud, Iskra Pusic, Peter Westervelt, Amanda F Cashen, Matt Christopher, Armin Ghobadi, Ramzi Abboud, Keith Stockerl-Goldstein, Geoffrey L Uy, John F. DiPersio, Leah Gehrs
Journal: Blood
Blood (2023) 142 (Supplement 1): 651.
https://doi.org/10.1182/blood-2023-180289
Published: 2023
Journal Articles

Impact of Cytarabine Pharmacogenomics on Survival of Adolescent and Young Adults with AML and Its Clinical Relevance in Black Patients

Richard J Marrero, Deedra Nicolet, Vivek M. Shastri, Krzysztof Mrózek, Christopher J. Walker, William Blum, Bayard L Powell, Jonathan E Kolitz, Joseph O Moore, Geoffrey L Uy, Wendy Stock, Andrew J Carroll, John C. Byrd, Ann-Kathrin Eisfeld, Jatinder K. Lamba
Journal: Blood
Blood (2023) 142 (Supplement 1): 2954.
https://doi.org/10.1182/blood-2023-187361
Published: 2023
Journal Articles

Risk Stratification of Patients with RUNX1- mutated Acute Myeloid Leukemia

Christian Rausch, Roman Hornung, Aarif M. N. Batcha, Maja Rothenberg-Thurley, Stefanos A. Bamopoulos, Vindi Jurinovic, Bianka Ksienzyk, Stephanie Schneider, Annika Maria Dufour, Michaela Neusser, Maria Cristina Sauerland, Dennis Görlich, Utz Krug, Wolfgang E. Berdel, Bernhard J. Woermann, Jan Braess, Wolfgang Hiddemann, Manja Meggendorfer, Wolfgang Kern, Torsten Haferlach, Johannes Schetelig, Moritz Middeke, Sebastian Stasik, Katharina Egger-Heidrich, Christoph Röllig, Martin Bornhäuser, Christian Thiede, Claudia D Baldus, Carsten Müller-Tidow, Uwe Platzbecker, Hubert Serve, Wendy Stock, Geoffrey L Uy, John C. Byrd, Deedra Nicolet, Ann-Kathrin Eisfeld, Ulrich Mansmann, Karsten Spiekermann, Klaus H Metzeler, Tobias Herold
Journal: Blood
Blood (2023) 142 (Supplement 1): 2934.
https://doi.org/10.1182/blood-2023-174059
Published: 2023
Journal Articles

Patient Recorded Outcomes from a Randomized, Controlled Phase 2 Trial of E-Selectin Inhibition with Uproleselan Vs Placebo to Reduce GI Toxicity during Melphalan-Conditioned Autologous Hematopoietic Cell Transplantation for Multiple Myeloma

Meaghan Ryan, Zachary David Crees, Michael Slade, Mark A. Schroeder, Ravi Vij, Geoffrey L Uy, Keith Stockerl-Goldstein
Journal: Blood
Blood (2023) 142 (Supplement 1): 2217.
https://doi.org/10.1182/blood-2023-179604
Published: 2023
Journal Articles

Multiomic Single-Cell Sequencing May Distinguish BCR-ABL-Mutated Acute Myeloid Leukemia (AML) from Blast Crisis Chronic Myelogenous Leukemia (BC-CML)

Vanessa E. Kennedy, Cheryl A C Peretz, Andrew Koh, Elaine Tran, Dalia Dhingra, Saurabh Gulati, Adam Sciambi, Olga Sala-Torra, Lan Beppu, Aaron C. Logan, Alexander Perl, Wendy Stock, Geoffrey L Uy, Ann-Kathrin Eisfeld, Jerald P. Radich, Catherine C. Smith
Journal: Blood
Blood (2023) 142 (Supplement 1): 4334.
https://doi.org/10.1182/blood-2023-182454
Published: 2023
Journal Articles

Consolidation Therapy with Blinatumomab Improves Overall Survival in Newly Diagnosed Adult Patients with B-Lineage Acute Lymphoblastic Leukemia in Measurable Residual Disease Negative Remission: Results from the ECOG-ACRIN E1910 Randomized Phase III National Cooperative Clinical Trials Network Trial

Mark R. Litzow, Zhuoxin Sun, Elisabeth Paietta, Ryan J. Mattison, Hillard M Lazarus, Jacob M. Rowe, Daniel A. Arber, Charles G. Mullighan, Cheryl L Willman, Yanming Zhang, Matthew Wieduwilt, Michaela Liedtke, Julie Bergeron, Keith W. Pratz, Shira Dinner, Noelle V. Frey, Steven D. Gore, Bhavana Bhatnagar, Ehab L. Atallah, Geoffrey L. Uy, Deepa Jeyakumar, Tara L. Lin, Richard F. Little, Selina M. Luger, Martin S. Tallman
Journal: Blood
Blood (2022) 140 (Supplement 2): LBA-1.
https://doi.org/10.1182/blood-2022-171751
Published: 2022
Journal Articles

The role of allogeneic transplant for adult Ph + ALL in CR1 with complete molecular remission: a retrospective analysis

CME Clinical Trials & Observations
Armin Ghobadi, Michael Slade, Hagop Kantarjian, Julio Alvarenga, Ibrahim Aldoss, Kahee A. Mohammed, Elias Jabbour, Rawan Faramand, Bijal Shah, Frederick Locke, Warren Fingrut, Jae H. Park, Nicholas J. Short, Feng Gao, Geoffrey L. Uy, Peter Westervelt, John F. DiPersio, Richard E. Champlin, Monzr M. Al Malki, Farhad Ravandi, Partow Kebriaei
Journal: Blood
Blood (2022) 140 (20): 2101–2112.
https://doi.org/10.1182/blood.2022016194
Published: 2022
Includes: Supplemental data