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Journal Articles

The biological and clinical impact of deletions before and after large chromosomal gains in multiple myeloma

Anthony M. Cirrincione, Alexandra M. Poos, Bachisio Ziccheddu, Marcella Kaddoura, Marc-Andrea Bärtsch, Kylee Maclachlan, Monika Chojnacka, Benjamin Diamond, Lukas John, Philipp Reichert, Stefanie Huhn, Patrick Blaney, Dylan Gagler, Karsten Rippe, Yanming Zhang, Ahmet Dogan, Alexander M. Lesokhin, Faith Davies, Hartmut Goldschmidt, Roland Fenk, Katja C. Weisel, Elias K. Mai, Neha Korde, Gareth J. Morgan, Saad Usmani, Ola Landgren, Marc S. Raab, Niels Weinhold, Francesco Maura
Journal: Blood
Blood (2024) 144 (7): 771–783.
https://doi.org/10.1182/blood.2024024299
Published: 2024
Includes: Supplemental data
Journal Articles

Clinical Outcomes Associated with Del(17p) in Newly Diagnosed Multiple Myeloma Treated with Triplet and Daratumumab-Based Quadruplet Induction Regimens

Eric Jurgens, Ross Firestone, Kylee H Maclachlan, David Nemirovsky, Andriy Derkach, Malin Hultcrantz, Hani Hassoun, Sham Mailankody, Urvi A Shah, Sridevi Rajeeve, Dhwani Patel, Tala Shekarkhand, Colin Rueda, Yanming Zhang, Oscar Boutros Lahoud, Gunjan L. Shah, Michael Scordo, David Chung, Heather Landau, Sergio A. Giralt, Alexander Lesokhin, Neha Korde, Saad Z Usmani, Carlyn Tan
Journal: Blood
Blood (2023) 142 (Supplement 1): 2024.
https://doi.org/10.1182/blood-2023-190728
Published: 2023
Journal Articles

Sitagliptin for Prevention of aGVHD in Patients Received Alternative Donor Transplantations: A Prospective, Multicenter, Open-Label, Randomized Controlled Trial

Man Qiao, Xiaofei Yang, Xiebing Bao, Jihao Zhou, Han Zhu, Yanming Zhang, Tao You, Huiying Qiu, Ying Wang, Shengli Xue, Aining Sun, Yue Han, Xiao Ma, Xiaojin Wu, Depei Wu, Suning Chen
Journal: Blood
Blood (2023) 142 (Supplement 1): 4922.
https://doi.org/10.1182/blood-2023-189348
Published: 2023
Journal Articles

Haploidentical Hematopoietic Cell Transplantation Combined with an Unrelated Cord Blood Unit for Adult Acute Myeloid Leukemia Results in Improved Survival Compared to Haploidentical Hematopoietic Cell Transplantation: Results of a Multicenter, Randomized, Phase III Trial

Biqi Zhou, Jia Chen, Tianhui Liu, Yanming Zhang, Yishan Ye, Yiyang Ding, Mingqing Zhu, Xiao Ma, Xiaoli Li, Zhihong Lin, He Huang, Yang Xu, Depei Wu
Journal: Blood
Blood (2023) 142 (Supplement 1): 1041.
https://doi.org/10.1182/blood-2023-180993
Published: 2023
Journal Articles

Assessment of Outcomes of Consolidation Therapy By Number of Cycles of Blinatumomab Received in Newly Diagnosed Measurable Residual Disease Negative Patients with B-Lineage Acute Lymphoblastic Leukemia: In the ECOG-ACRIN E1910 Randomized Phase III National Clinical Trials Network Trial

Selina M Luger, Zhuoxin Sun, Ryan J Mattison, Elisabeth Paietta, Kathryn G. Roberts, Yanming Zhang, Janis Racevckis, Hillard M. Lazarus, Jacob M. Rowe, Daniel A. Arber, Matthew J. Wieduwilt, Michaela Liedtke, Julie Bergeron, Brent L. Wood, Yaqi Zhao, Gang Wu, Ti-Cheng Chang, Wenchao Zhang, Keith W Pratz, Shira N. Dinner, Noelle V. Frey, Steven D. Gore, Bhavana Bhatnagar, Ehab L. Atallah, Geoffrey L Uy, Deepa Jeyakumar, Tara L Lin, Cheryl L. Willman, Daniel J. DeAngelo, Elad Sharon, Richard F. Little, Harry P. Erba, Richard M Stone, Charles G. Mullighan, Mark R. Litzow, Martin S. Tallman
Journal: Blood
Blood (2023) 142 (Supplement 1): 2877.
https://doi.org/10.1182/blood-2023-189648
Published: 2023
Journal Articles

Clinical Characteristics and Outcomes of Limited Stage High Grade B-Cell Lymphoma with MYC/BCL2 and/or BCL6 Rearrangements: A Single Center Experience

Jennifer Kimberly Lue, Efrat Luttwak, Philip Caron, Alexander P. Boardman, Kevin A. David, Alfredo Rivas-Delgado, Zachary D. Epstein-Peterson, Lorenzo Falchi, Paola Ghione, Paul A. Hamlin, Steven M. Horwitz, Andrew M. Intlekofer, William Johnson, Anita Kumar, Alison Moskowitz, Ariela Noy, Maria Lia Palomba, Robert Stuver, Pallawi Torka, Santosha A Vardhana, Andrew D. Zelenetz, Yanming Zhang, Pallavi Galera, Ahmet Dogan, Umut Aypar, Gilles Salles
Journal: Blood
Blood (2023) 142 (Supplement 1): 3129.
https://doi.org/10.1182/blood-2023-173562
Published: 2023
Journal Articles

The Complex Structural Variant Chromothripsis Can be Defined on Targeted Sequencing Panels, Allowing Direct Clinical Translation in Order to Improve Multiple Myeloma Prognostication

Kylee H Maclachlan, Bachisio Ziccheddu, Carlyn Tan, Tala Shekarkhand, Colin Rueda, Edith Serrano, Benjamin Diamond, Hani Hassoun, Sham Mailankody, Urvi A Shah, Malin Hultcrantz, Sergio A. Giralt, David Chung, Heather Landau, Oscar Boutros Lahoud, Michael Scordo, Gunjan L. Shah, Yanming Zhang, Robert Cimera, Maria E. Arcila, Ola Landgren, Alexander Lesokhin, Neha Korde, Francesco Maura, Saad Z Usmani
Journal: Blood
Blood (2023) 142 (Supplement 1): 3343.
https://doi.org/10.1182/blood-2023-189316
Published: 2023
Journal Articles

Revealing Novel Mechanisms Underlying Inactivation of Tumor Suppressor Genes on Duplicated Chromosomes in Multiple Myeloma

Anthony Cirrincione, Marcella Kaddoura, Alexandra Maria Poos, Bachisio Ziccheddu, Kylee H Maclachlan, Monika Chojnacka, Benjamin Diamond, Patrick Blaney, Dylan Gagler, Yanming Zhang, Ahmet Dogan, Alexander Lesokhin, Faith E. Davies, Hartmut Goldschmidt, Katja Weisel, Roland Fenk, Elias K. Mai, Neha Korde, Gareth J. Morgan, Marc S. Raab, Saad Z Usmani, Ola Landgren, Niels Weinhold, Francesco Maura
Journal: Blood
Blood (2023) 142 (Supplement 1): 874.
https://doi.org/10.1182/blood-2023-186802
Published: 2023
Journal Articles

Comprehensive Genomic Characterization of Response and Resistance to Daratumumab-Based Quadruplet Induction in Newly Diagnosed Multiple Myeloma Patients

Kylee H Maclachlan, Carlyn Rose Tan, Tala Shekarkhand, Colin Rueda, Edith Serrano, David Nemirovsky, Andriy Derkach, Andrew McPherson, Benjamin Diamond, Bachisio Ziccheddu, Eileen Boyle, Hani Hassoun, Sham Mailankody, Urvi A Shah, Malin Hultcrantz, Sergio A. Giralt, David Chung, Heather Landau, Oscar Boutros Lahoud, Michael Scordo, Gunjan L. Shah, Yanming Zhang, Robert Cimera, Maria E. Arcila, Ahmet Dogan, Alexander Lesokhin, Gareth J. Morgan, Ola Landgren, Francesco Maura, Neha Korde, Saad Z Usmani
Journal: Blood
Blood (2023) 142 (Supplement 1): 3370.
https://doi.org/10.1182/blood-2023-187891
Published: 2023
Journal Articles

A Pro-Inflammatory Gene Signature Characterizes a Better Risk Aged AML Patient Group in ECOG-ACRIN Cancer Research Group's Clinical Trial E3999

Yaseswini Neelamraju, Franck Rapaport, Jorge A Gandara, Nicholas Dunham, Hao Fan, Tak Lee, Subhash Prajapati, Caroline Sheridan, Ling Wang, Larry D. Cripe, Richard Dillon, Maria Kleppe, Ross L Levine, Christopher Mason, Ari M Melnick, Elisabeth Paietta, Gail J. Roboz, Zhuoxin Sun, Martin S. Tallman, Yanming Zhang, Stefan Bekiranov, Francine E. Garrett-Bakelman
Journal: Blood
Blood (2023) 142 (Supplement 1): 4326.
https://doi.org/10.1182/blood-2023-179569
Published: 2023
Journal Articles

Chidamide Combined with a Modified Bu-Cy Conditioning Regimen Improves Survival in Patients with T-Cell Acute Lymphoblastic Leukemia/Lymphoma Undergoing Allogeneic Hematopoietic Stem Cell Transplantation

Xuanqi Cao, Zheng Li, Yanming Zhang, Qingya Cui, Yunju Ma, Mengyun Li, Sifan Chen, Jia Yin, Wei Cui, Jia Chen, Aining Sun, Huiying Qiu, Suning Chen, Zhengming Jin, Xiaming Zhu, De-Pei Wu, Xiaowen Tang
Journal: Blood
Blood (2023) 142 (Supplement 1): 6959.
https://doi.org/10.1182/blood-2023-185258
Published: 2023
Journal Articles

Tracking the evolution of therapy-related myeloid neoplasms using chemotherapy signatures

Benjamin Diamond, Bachisio Ziccheddu, Kylee Maclachlan, Justin Taylor, Eileen Boyle, Juan Arango Ossa, Jacob Jahn, Maurizio Affer, Tulasigeri M. Totiger, David Coffey, Namrata Chandhok, Justin Watts, Luisa Cimmino, Sydney X. Lu, Niccolò Bolli, Kelly Bolton, Heather Landau, Jae H. Park, Karuna Ganesh, Andrew McPherson, Mikkael A. Sekeres, Alexander Lesokhin, David J. Chung, Yanming Zhang, Caleb Ho, Mikhail Roshal, Jeffrey Tyner, Stephen Nimer, Elli Papaemmanuil, Saad Usmani, Gareth Morgan, Ola Landgren, Francesco Maura
Journal: Blood
Blood (2023) 141 (19): 2359–2371.
https://doi.org/10.1182/blood.2022018244
Published: 2023
Includes: Supplemental data
Journal Articles

Consolidation Therapy with Blinatumomab Improves Overall Survival in Newly Diagnosed Adult Patients with B-Lineage Acute Lymphoblastic Leukemia in Measurable Residual Disease Negative Remission: Results from the ECOG-ACRIN E1910 Randomized Phase III National Cooperative Clinical Trials Network Trial

Mark R. Litzow, Zhuoxin Sun, Elisabeth Paietta, Ryan J. Mattison, Hillard M Lazarus, Jacob M. Rowe, Daniel A. Arber, Charles G. Mullighan, Cheryl L Willman, Yanming Zhang, Matthew Wieduwilt, Michaela Liedtke, Julie Bergeron, Keith W. Pratz, Shira Dinner, Noelle V. Frey, Steven D. Gore, Bhavana Bhatnagar, Ehab L. Atallah, Geoffrey L. Uy, Deepa Jeyakumar, Tara L. Lin, Richard F. Little, Selina M. Luger, Martin S. Tallman
Journal: Blood
Blood (2022) 140 (Supplement 2): LBA-1.
https://doi.org/10.1182/blood-2022-171751
Published: 2022
Journal Articles

Quantitative Cytogenetic Analysis with karyoParser Allows for More Precise Identification of Disease Biology, Clonal Evolution, and Etiology of Relapse in Acute Myeloid Leukemia

Deepika Dilip, Andriy Derkach, Kamal Menghrajani, Aaron D Goldberg, Hannah May, Virginia M. Klimek, Pallavi K Galera, Wenbin Xiao, Yanming Zhang, Olivier Elemento, Ross L. Levine, Jacob L Glass
Journal: Blood
Blood (2022) 140 (Supplement 1): 9119–9121.
https://doi.org/10.1182/blood-2022-170847
Published: 2022
Journal Articles

Tracking the Evolution of Therapy-Related Myeloid Neoplasms Using Chemotherapy Signatures

Bachisio Ziccheddu, Benjamin Diamond, Kylee H Maclachlan, Justin Taylor, Eileen M Boyle, Juan E. Arango Ossa, Jahn Jacob, Maurizio Affer, Tulasigeri M Totiger, David Coffey, Justin Watts, Sydney X. Lu, Niccolo Bolli, Kelly L Bolton, Jae H Park, Heather Landau, Karuna Ganesh, Andrew McPherson, Mikkael A. Sekeres, Alexander M Lesokhin, David J. Chung, Yanming Zhang, Caleb Ho, Mikhail Roshal, Jeffrey W. Tyner, Stephen D Nimer, Elli Papaemmanuil, Saad Usmani, Gareth J. Morgan, Ola Landgren, Francesco Maura
Journal: Blood
Blood (2022) 140 (Supplement 1): 2088–2090.
https://doi.org/10.1182/blood-2022-158992
Published: 2022
Journal Articles

Genomic Determinants of Resistance in Newly Diagnosed Multiple Myeloma Treated with Targeted-Immunotherapy

Francesco Maura, Eileen Boyle, David Coffey, Kylee H Maclachlan, Benjamin Diamond, Patrick Blaney, Dylan Gagler, Bachisio Ziccheddu, Hussein Ghamlouch, Yubao Wang, James E. Hoffman, Dickran Kazandjian, Hani Hassoun, Emily Guzman, Sham Mailankody, Urvi A Shah, Carlyn Tan, Malin Hultcrantz, Michael Scordo, Gunjan L. Shah, Heather Landau, David J. Chung, Sergio A. Giralt, Yanming Zhang, Ahmet Dogan, Alexander M Lesokhin, Dennis Verducci, Faith E. Davies, Saad Usmani, Neha Korde, Gareth J. Morgan, Ola Landgren
Journal: Blood
Blood (2022) 140 (Supplement 1): 1137–1139.
https://doi.org/10.1182/blood-2022-160308
Published: 2022
Journal Articles

Autologous Versus Haploidentical Stem Cell Transplantation in Adult Patients with Intermediate Risk Actue Myelogenous Leukemia in First Complete Remission and Undetectable Minimal Residual Disease: A Global Preliminary Analysis of Chinese Data

Jia Chen, Yiyang Ding, Xi Zhang, Erlie Jiang, Lin Liu, He Huang, Jiong Hu, Jishi Wang, Yanming Zhang, Myriam Labopin, Irma Khvedelidze, Emmanuelle Polge, Arnon Nagler, Mohamad Mohty, Depei Wu, Norbert Claude Gorin, Sr.
Journal: Blood
Blood (2022) 140 (Supplement 1): 12952–12953.
https://doi.org/10.1182/blood-2022-165709
Published: 2022
Journal Articles

Erythroid and Megakaryocytic Differentiation Program in JAK2 -Mutated Acute Myeloid Leukemia with or without Antecedent Myeloproliferative Neoplasm

Ying Liu, Shenon Sethi, Richard Koche, Qi Gao, Deepika Dilip, Jacob L Glass, Pallavi K Galera, Sonali Persaud, Tanmay Mishra, Xiaotian Sun, Dory Londono, Robert Cimera, Menglei Zhu, Christopher Famulare, Jeeyeon Baik, Himanshu Bhurtel, Maria E. Arcila, Ahmet Dogan, Ross L. Levine, Yanming Zhang, Mikhail Roshal, Raajit K Rampal, Wenbin Xiao
Journal: Blood
Blood (2022) 140 (Supplement 1): 9160–9162.
https://doi.org/10.1182/blood-2022-169215
Published: 2022
Journal Articles

Fc-Mediated Antibody Effector Function, Inflammation Resolution and Oligoclonality on TCR Rearrangements Predict Sustained MRD Negativity in Newly Diagnosed Multiple Myeloma Treated with Immunotherapy Regimens

Eileen M Boyle, Francesco Maura, David Coffey, Kylee H Maclachlan, Benjamin Diamond, Hussein Ghamlouch, Dylan Gagler, Patrick Blaney, Bachisio Ziccheddu, Yubao Wang, Emily Guzman, Avital Tenenbaum, Ariel Siegel, Xiaoyi Chen, Gaurav Varma, James E Hoffman, Dickran Kazandjian, Hani Hassoun, Sham Mailankody, Urvi A Shah, Carlyn Tan, Malin Hultcrantz, Michael Scordo, Gunjan L. Shah, Heather Landau, David J. Chung, Sergio A Giralt, Yanming Zhang, Ahmet Dogan, Alexander M Lesokhin, Dennis Verducci, Faith E Davies, Saad Usmani, Neha Korde, Ola Landgren, Gareth J. Morgan
Journal: Blood
Blood (2022) 140 (Supplement 1): 249–251.
https://doi.org/10.1182/blood-2022-165500
Published: 2022
Journal Articles

Tracking the Earliest Genomic Events in Multiple Myeloma Life-History

Anthony Cirrincione, Bachisio Ziccheddu, Kylee H Maclachlan, Alexandra M. Poos, Monika Chojnacka, Benjamin Diamond, Eileen M Boyle, Patrick Blaney, Dylan Gagler, Yanming Zhang, Ahmet Dogan, Alexander M Lesokhin, Faith E. Davies, Neha Korde, Marc S Raab, Niels Weinhold, Saad Usmani, Gareth J. Morgan, Ola Landgren, Francesco Maura
Journal: Blood
Blood (2022) 140 (Supplement 1): 1553–1555.
https://doi.org/10.1182/blood-2022-164742
Published: 2022