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Journal Articles

Changes in Methylation and Chromatin Accessibility Underlie Subtype Classification and Disease Evolution in Waldenström's Macroglobulinemia

Zachary R Hunter, Nickolas Tsakmaklis, Kris Richardson, Maria Luisa Guerrera, Amanda Kofides, Xia Liu, Shirong Liu, Catherine A. Flynn, Kirsten Meid, Christopher J Patterson, Mariateresa Fulciniti, Mehmet K. Samur, Kenneth C. Anderson, Nikhil C Munshi, Shayna R Sarosiek, Jorge J. Castillo, Ari M Melnick, Steven P Treon

Blood (2023) 142 (Supplement 1): 755.

https://doi.org/10.1182/blood-2023-190825

Published: 2023

Journal Articles

Inhibition of EZH2 Improves CART19 Immunotherapy By Reprogramming Lymphoma Tumor Cells and Enhancing T-Cell Functionality

Patrizia Porazzi, Yusuke Isshiki, Guido Ghilardi, Siena Nason, Ziqi Yang, Alberto Carturan, Linhui Chen, Yunlin Zhang, Ruchi P. Patel, Puneeth Guruprasad, Ositadimma Ugwuanyi, Ivan J Cohen, Stephen J Schuster, Ari M Melnick, Wendy BÃ©guelin, Marco Ruella

Blood (2023) 142 (Supplement 1): 1018.

https://doi.org/10.1182/blood-2023-182440

Published: 2023

Journal Articles

Cooperative Super-Enhancer Inactivation through Loss of Crebbp and KMT2D Skews B Cell Fate Decisions and Yields T Cell-Depleted Lymphomas

Jie Li, Christopher Chin, Hsia-Yuan Ying, Cem Meydan, Matthew Teater, Min Xia, Pedro Farinha, Katsuyoshi Takata, Chi-Shuen Chu, Martin A Rivas, Amy Chadburn, Christian Steidl, David W. Scott, Robert G. Roeder, Christopher Mason, Wendy BÃ©guelin, Ari M Melnick

Blood (2023) 142 (Supplement 1): 2776.

https://doi.org/10.1182/blood-2023-174501

Published: 2023

Journal Articles

EZH2 Inhibitors Enhance CART Cell Quality, Efficacy, In Vivo Homing, Tumor Cell Binding and Killing of Fully Syngeneic Primary B Cell Lymphomas, As Well As Reprogramming Lymphoma Cells to a Highly Immunogenic and T Cell Adherent Phenotype

Yusuke Isshiki, Patrizia Porazzi, Xi Chen, Matthew Teater, Ioannis Karagiannidis, Henna S. Nam, Ari M Melnick, Marco Ruella, Wendy BÃ©guelin

Blood (2023) 142 (Supplement 1): 432.

https://doi.org/10.1182/blood-2023-190610

Published: 2023

Journal Articles

T-Cell Signaling Mediates the Epigenetic Priming of Germinal Center B-Cell Plasticity and Stem Functionality

Laurianne Scourzic, Franco Izzo, Lucretia Cucereavii, Matthew Teater, Alexander Polyzos, Christopher Chin, Coraline Mlynarczyk, Ioanna Tsialta, Robert M Myers, Wendy BÃ©guelin, Matthias Stadtfeld, Zhengming Chen, Dan A. Landau, Ari M Melnick, Eftychia Apostolou

Blood (2023) 142 (Supplement 1): 2767.

https://doi.org/10.1182/blood-2023-190437

Published: 2023

Journal Articles

SWI/SNF Chromatin Remodeling Complex Orchestrates Sequential Binding of Key Transcription Factors in B Cells and Restricts Aggressive Lymphoma

Darko Barisic, Christopher Chin, Cem Meydan, Matthew Teater, Ioanna Tsialta, Coraline Mlynarczyk, Amy Chadburn, Min Xia, Christian Steidl, David W. Scott, Andrew P. Weng, Christopher Mason, Michael R. Green, Ari M Melnick

Blood (2023) 142 (Supplement 1): 718.

https://doi.org/10.1182/blood-2023-190494

Published: 2023

Journal Articles

CTCF Is a Haploinsufficient Tumor Suppressor in B-Cell Lymphoma

Martin A Rivas, Dajiang Guo, Catherine Do, Jane Skok, Ari M Melnick

Blood (2023) 142 (Supplement 1): 1398.

https://doi.org/10.1182/blood-2023-173696

Published: 2023

Journal Articles

Development of Syngeneic Murine Cell Lines of Germinal Center-Derived B-Cell Lymphomas

Henna S. Nam, Yusuke Isshiki, Min Xia, Sanket Shah, Meng Li, Ioannis Karagiannidis, Matthew Teater, Ari M Melnick, Wendy BÃ©guelin

Blood (2023) 142 (Supplement 1): 4365.

https://doi.org/10.1182/blood-2023-186686

Published: 2023

Journal Articles

A Pro-Inflammatory Gene Signature Characterizes a Better Risk Aged AML Patient Group in ECOG-ACRIN Cancer Research Group's Clinical Trial E3999

Blood (2023) 142 (Supplement 1): 4326.

https://doi.org/10.1182/blood-2023-179569

Published: 2023

Journal Articles

Loss of CCAAT‐Enhancer Binding Protein Delta Promotes Acute Myeloid Leukemia Cell Proliferation and Survival By Upregulating Cyclin D1 Expression

Blood (2023) 142 (Supplement 1): 1380.

https://doi.org/10.1182/blood-2023-181946

Published: 2023

Journal Articles

Endothelial cell–leukemia interactions remodel drug responses, uncovering T-ALL vulnerabilities

Blood (2023) 141 (5): 503–518.

https://doi.org/10.1182/blood.2022015414

Published: 2023

Includes: Supplemental data

Journal Articles

Genomic profiling for clinical decision making in lymphoid neoplasms

Laurence de Leval, Ash A. Alizadeh, P. Leif Bergsagel, Elias Campo, Andrew Davies, Ahmet Dogan, Jude Fitzgibbon, Steven M. Horwitz, Ari M. Melnick, William G. Morice, Ryan D. Morin, Bertrand Nadel, Stefano A. Pileri, Richard Rosenquist, Davide Rossi, Itziar Salaverria, Christian Steidl, Steven P. Treon, Andrew D. Zelenetz, Ranjana H. Advani, Carl E. Allen, Stephen M. Ansell, Wing C. Chan, James R. Cook, Lucy B. Cook, Francesco d’Amore, Stefan Dirnhofer, Martin Dreyling, Kieron Dunleavy, Andrew L. Feldman, Falko Fend, Philippe Gaulard, Paolo Ghia, John G. Gribben, Olivier Hermine, Daniel J. Hodson, Eric D. Hsi, Giorgio Inghirami, Elaine S. Jaffe, Kennosuke Karube, Keisuke Kataoka, Wolfram Klapper, Won Seog Kim, Rebecca L. King, Young H. Ko, Ann S. LaCasce, Georg Lenz, José I. Martin-Subero, Miguel A. Piris, Stefania Pittaluga, Laura Pasqualucci, Leticia Quintanilla-Martinez, Scott J. Rodig, Andreas Rosenwald, Gilles A. Salles, Jesus San-Miguel, Kerry J. Savage, Laurie H. Sehn, Gianpietro Semenzato, Louis M. Staudt, Steven H. Swerdlow, Constantine S. Tam, Judith Trotman, Julie M. Vose, Oliver Weigert, Wyndham H. Wilson, Jane N. Winter, Catherine J. Wu, Pier L. Zinzani, Emanuele Zucca, Adam Bagg, David W. Scott

Blood (2022) 140 (21): 2193–2227.

https://doi.org/10.1182/blood.2022015854

Published: 2022

Includes: Supplemental data

Journal Articles

The International Consensus Classification of Mature Lymphoid Neoplasms: a report from the Clinical Advisory Committee

Elias Campo, Elaine S. Jaffe, James R. Cook, Leticia Quintanilla-Martinez, Steven H. Swerdlow, Kenneth C. Anderson, Pierre Brousset, Lorenzo Cerroni, Laurence de Leval, Stefan Dirnhofer, Ahmet Dogan, Andrew L. Feldman, Falko Fend, Jonathan W. Friedberg, Philippe Gaulard, Paolo Ghia, Steven M. Horwitz, Rebecca L. King, Gilles Salles, Jesus San-Miguel, John F. Seymour, Steven P. Treon, Julie M. Vose, Emanuele Zucca, Ranjana Advani, Stephen Ansell, Wing-Yan Au, Carlos Barrionuevo, Leif Bergsagel, Wing C. Chan, Jeffrey I. Cohen, Francesco d’Amore, Andrew Davies, Brunangelo Falini, Irene M. Ghobrial, John R. Goodlad, John G. Gribben, Eric D. Hsi, Brad S. Kahl, Won-Seog Kim, Shaji Kumar, Ann S. LaCasce, Camille Laurent, Georg Lenz, John P. Leonard, Michael P. Link, Armando Lopez-Guillermo, Maria Victoria Mateos, Elizabeth Macintyre, Ari M. Melnick, Franck Morschhauser, Shigeo Nakamura, Marina Narbaitz, Astrid Pavlovsky, Stefano A. Pileri, Miguel Piris, Barbara Pro, Vincent Rajkumar, Steven T. Rosen, Birgitta Sander, Laurie Sehn, Margaret A. Shipp, Sonali M. Smith, Louis M. Staudt, Catherine Thieblemont, Thomas Tousseyn, Wyndham H. Wilson, Tadashi Yoshino, Pier-Luigi Zinzani, Martin Dreyling, David W. Scott, Jane N. Winter, Andrew D. Zelenetz

Blood (2022) 140 (11): 1229–1253.

https://doi.org/10.1182/blood.2022015851

Published: 2022

Includes: Supplemental data

Journal Articles

Evolution of the Tumor Microenvironment throughout Progression and Transformation of EZH2 Mutant Follicular Lymphoma

Yusuke Isshiki, Dylan McNally, Ari M. Melnick, Wendy Béguelin

Blood (2021) 138 (Supplement 1): 446.

https://doi.org/10.1182/blood-2021-148996

Published: 2021

Journal Articles

Allele-specific expression of GATA2 due to epigenetic dysregulation in CEBPA double-mutant AML

Roger Mulet-Lazaro, Stanley van Herk, Claudia Erpelinck, Eric Bindels, Mathijs A. Sanders, Carlo Vermeulen, Ivo Renkens, Peter Valk, Ari M. Melnick, Jeroen de Ridder, Michael Rehli, Claudia Gebhard, Ruud Delwel, Bas J. Wouters

Blood (2021) 138 (2): 160–177.

https://doi.org/10.1182/blood.2020009244

Published: 2021

Includes: Supplemental data

Journal Articles

The dangers of déjà vu: memory B cells as the cells of origin of ABC-DLBCLs

Leandro Venturutti, Ari M. Melnick

Blood (2020) 136 (20): 2263–2274.

https://doi.org/10.1182/blood.2020005857

Published: 2020

Journal Articles

Characterization of Complete Lncrnas Transcriptome Reveals Expression of Lncrnas As a Prognostic Factor and Linc-Smilo As a Potential Therapeutic Target in Multiple Myeloma

Blood (2019) 134 (Supplement_1): 4323.

https://doi.org/10.1182/blood-2019-123008

Published: 2019

Journal Articles

Computational Systems Biology Models for the Identification of Metabolic Vulnerabilities in Multiple Myeloma

Luis Vitores V. Valcárcel, MSc, Raquel Ordoñez, PhD, Iñigo Apaolaza, MSc, Ana Valcárcel, Leire Garate, Cem Meydan, PhD, Bruno Paiva, PhD, Ari M Melnick, MD, Jesús San-Miguel, Francisco J. Planes, Xabier Agirre, PhD, Felipe Prosper, MD PhD

Blood (2019) 134 (Supplement_1): 3084.

https://doi.org/10.1182/blood-2019-123970

Published: 2019

Journal Articles

Small-molecule BCL6 inhibitor effectively treats mice with nonsclerodermatous chronic graft-versus-host disease

Blood (2019) 133 (1): 94–99.

https://doi.org/10.1182/blood-2018-03-839993

Published: 2019

Journal Articles

Molecular and Genetic Characterization of MHC Deficiency Identifies EZH2 As a Therapeutic Target for Restoring MHC Expression in Diffuse Large B-Cell Lymphoma

Blood (2018) 132 (Supplement 1): 1560.

https://doi.org/10.1182/blood-2018-99-112010

Published: 2018

NARROW

Changes in Methylation and Chromatin Accessibility Underlie Subtype Classification and Disease Evolution in Waldenström's Macroglobulinemia

Inhibition of EZH2 Improves CART19 Immunotherapy By Reprogramming Lymphoma Tumor Cells and Enhancing T-Cell Functionality

Cooperative Super-Enhancer Inactivation through Loss of Crebbp and KMT2D Skews B Cell Fate Decisions and Yields T Cell-Depleted Lymphomas

EZH2 Inhibitors Enhance CART Cell Quality, Efficacy, In Vivo Homing, Tumor Cell Binding and Killing of Fully Syngeneic Primary B Cell Lymphomas, As Well As Reprogramming Lymphoma Cells to a Highly Immunogenic and T Cell Adherent Phenotype

T-Cell Signaling Mediates the Epigenetic Priming of Germinal Center B-Cell Plasticity and Stem Functionality

SWI/SNF Chromatin Remodeling Complex Orchestrates Sequential Binding of Key Transcription Factors in B Cells and Restricts Aggressive Lymphoma

CTCF Is a Haploinsufficient Tumor Suppressor in B-Cell Lymphoma

Development of Syngeneic Murine Cell Lines of Germinal Center-Derived B-Cell Lymphomas

A Pro-Inflammatory Gene Signature Characterizes a Better Risk Aged AML Patient Group in ECOG-ACRIN Cancer Research Group's Clinical Trial E3999

Loss of CCAAT‐Enhancer Binding Protein Delta Promotes Acute Myeloid Leukemia Cell Proliferation and Survival By Upregulating Cyclin D1 Expression

Endothelial cell–leukemia interactions remodel drug responses, uncovering T-ALL vulnerabilities

Genomic profiling for clinical decision making in lymphoid neoplasms

The International Consensus Classification of Mature Lymphoid Neoplasms: a report from the Clinical Advisory Committee

Evolution of the Tumor Microenvironment throughout Progression and Transformation of EZH2 Mutant Follicular Lymphoma

Allele-specific expression of GATA2 due to epigenetic dysregulation in CEBPA double-mutant AML

The dangers of déjà vu: memory B cells as the cells of origin of ABC-DLBCLs

Characterization of Complete Lncrnas Transcriptome Reveals Expression of Lncrnas As a Prognostic Factor and Linc-Smilo As a Potential Therapeutic Target in Multiple Myeloma

Computational Systems Biology Models for the Identification of Metabolic Vulnerabilities in Multiple Myeloma

Small-molecule BCL6 inhibitor effectively treats mice with nonsclerodermatous chronic graft-versus-host disease

Molecular and Genetic Characterization of MHC Deficiency Identifies EZH2 As a Therapeutic Target for Restoring MHC Expression in Diffuse Large B-Cell Lymphoma

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American Society of Hematology

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American Society of Hematology

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