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Journal Articles

Spen loss drives extra-follicular diffuse large B cell lymphoma with female-specific lethality and TLR pathway therapeutic vulnerabilities

Free
Benedikt Pelzer, Cem Meydan, Isaac Spiegel, Ioannis Karagiannidis, Min Xia, Matthew Teater, Emma Welter, Zowie Searcy, Laura Hilton, Darko Barisic, Pengyan Fa, Shenon Sethi, Irem Isgor, Jessie Fielding, Alireza Karbalyhareh, Colin Burdette, Sravya Tumuluru, Sonia Debek, Sunjae Lee, Ramon Massoni-Badosa, Ceyda Durmaz, Eralda Salataj, Prasath Pararajalingam, Zhengming Chen, Richard Pelzl, Sanket Shah, Martin Rivas, Kenneth Hoehn, Coraline Mlynarczyk, Hannah Isles, Ahmet Dogan, Kojo Elenitoba-Johnson, David Scott, Kostiantyn Dreval, Ryan Morin, Christina Leslie, Rishi Puri, Jacob Geri, Christopher Chin, Amy Chadburn, Christopher Mason, Hans Christian Reinhardt, Montserrat Anguera, Wendy Béguelin, Leandro Venturutti, Ari Melnick
Journal: Blood
Blood (2025) 146 (Supplement 1): 140.
https://doi.org/10.1182/blood-2025-140
Published: 2025
Journal Articles

Development of Syngeneic Murine Cell Lines of Germinal Center-Derived B-Cell Lymphomas

Free
Henna S. Nam, Yusuke Isshiki, Min Xia, Sanket Shah, Meng Li, Ioannis Karagiannidis, Matthew Teater, Ari M Melnick, Wendy Béguelin
Journal: Blood
Blood (2023) 142 (Supplement 1): 4365.
https://doi.org/10.1182/blood-2023-186686
Published: 2023
Journal Articles

Cooperative Super-Enhancer Inactivation through Loss of Crebbp and KMT2D Skews B Cell Fate Decisions and Yields T Cell-Depleted Lymphomas

Free
Jie Li, Christopher Chin, Hsia-Yuan Ying, Cem Meydan, Matthew Teater, Min Xia, Pedro Farinha, Katsuyoshi Takata, Chi-Shuen Chu, Martin A Rivas, Amy Chadburn, Christian Steidl, David W. Scott, Robert G. Roeder, Christopher Mason, Wendy Béguelin, Ari M Melnick
Journal: Blood
Blood (2023) 142 (Supplement 1): 2776.
https://doi.org/10.1182/blood-2023-174501
Published: 2023
Journal Articles

SWI/SNF Chromatin Remodeling Complex Orchestrates Sequential Binding of Key Transcription Factors in B Cells and Restricts Aggressive Lymphoma

Free
Darko Barisic, Christopher Chin, Cem Meydan, Matthew Teater, Ioanna Tsialta, Coraline Mlynarczyk, Amy Chadburn, Min Xia, Christian Steidl, David W. Scott, Andrew P. Weng, Christopher Mason, Michael R. Green, Ari M Melnick
Journal: Blood
Blood (2023) 142 (Supplement 1): 718.
https://doi.org/10.1182/blood-2023-190494
Published: 2023
Journal Articles

MALT1 Degradation with a Proteolysis-Targeting Chimera for the Treatment of Activated B-Cell Type Diffuse Large B-Cell Lymphoma

Free
Madhav R Seshadri, Lorena Fontan, Prasanna Sreevatsan, David Scott, John Hatcher, Guangyan Du, Min Xia, Ilkay Us, Nathanael Gray, Ari Melnick
Journal: Blood
Blood (2021) 138 (Supplement 1): 269.
https://doi.org/10.1182/blood-2021-153855
Published: 2021
Journal Articles

Identification of MALT1 feedback mechanisms enables rational design of potent antilymphoma regimens for ABC-DLBCL

Free
Lorena Fontan, Rebecca Goldstein, Gabriella Casalena, Matthew Durant, Matthew R. Teater, Jimmy Wilson, Jude Phillip, Min Xia, Shivem Shah, Ilkay Us, Himaly Shinglot, Ankur Singh, Giorgio Inghirami, Ari Melnick
Journal: Blood
Blood (2021) 137 (6): 788–800.
https://doi.org/10.1182/blood.2019004713
Published: 2021
Includes: Supplemental data
Journal Articles

BCL10 Gain-of-Function Mutations Aberrantly Induce Canonical and Non-Canonical NF-Kb Activation and Resistance to Ibrutinib in ABC-DLBCL

Free
Min Xia, Liron David, PhD, Matthew Teater, PhD, Ozlem Onder, PhD MSc, Kojo S. J. Elenitoba-Johnson, MD, Lorena Fontan, PhD, Hao Wu, PhD, Ari Melnick, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 2–3.
https://doi.org/10.1182/blood-2020-141363
Published: 2020
Journal Articles

Mapping MALT1 Signaling Connectivity Unveils Novel B-Cell Feedback Mechanisms Directing Assembly of Potent Anti-Lymphoma Regimens

Free
Lorena Fontan, PhD, Matthew Durant, Rebecca Goldstein, PhD, Matthew R Teater, PhD, Gabriella Casalena, PhD, Min Xia, PhD, Jimmy Wilson, Ilkay Us, Giorgio Inghirami, MD, Ari Melnick, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 173.
https://doi.org/10.1182/blood-2019-130516
Published: 2019