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Journal Articles

Gene expression profiling reveals two overarching types of ALCL with distinct targetable biology: an LLMPP study

Andrew L. Feldman, Surendra Dasari, Lisa M. Rimsza, David W. Scott, Naoki Oishi, Guangzhen Hu, Pedro Farinha, Catalina Amador, Elías Campo, Wing C. Chan, James R. Cook, Jan Delabie, Kai Fu, Timothy C Greiner, Laura K Hilton, Giorgio GA Inghirami, Javeed Iqbal, Elaine S Jaffe, Ryan Morin, Sarah L. Ondrejka, German Ott, Stefania Pittaluga, Philipp W Raess, Andreas Rosenwald, Kerry J. Savage, Graham W. Slack, Susan L. Slager, Joo Y Song, George Wright, Hao-Wei Wang, Yu Zeng, Tadashi Yoshino, Xiaojun Wu, Ryan A Wilcox, xueju wang, Min Shi, Akira Satou, Anamarija M Perry, Roberto Nicolas Miranda, L.Jeffrey Jeffrey Medeiros, Matthew J Maurer, Eric Mou, Young Hyeh Ko, Kennosuke Karube, Brad S Kahl, Liuyan Jiang, David L Jaye, Alejandro Gru, Laurence L de Leval, Weina Chen, Jennifer R. Chapman, James R Cerhan, Carlos Barrionuevo, Stephen M. Ansell, Ahmed Aljudi

Blood blood.2024027700.

https://doi.org/10.1182/blood.2024027700

Published: 2025

Includes: Supplemental data

Journal Articles

Evaluating targeted long-read sequencing as a diagnostic tool for burkitt lymphoma

Giuliano Banco, Kostiantyn Dreval, Laura Hilton, David Scott, Michael J. Trimble, Amy H. Y. Lee, Krysta Coyle, Ryan Morin

Blood (2025) 146 (Supplement 1): 3547.

https://doi.org/10.1182/blood-2025-3547

Published: 2025

Journal Articles

Spen loss drives extra-follicular diffuse large B cell lymphoma with female-specific lethality and TLR pathway therapeutic vulnerabilities

Blood (2025) 146 (Supplement 1): 140.

https://doi.org/10.1182/blood-2025-140

Published: 2025

Journal Articles

Integrated multi-omic profiling reveals two biologically distinct subgroups of splenic marginal zone lymphoma with prognostic relevance

Blood (2025) 146 (Supplement 1): 353.

https://doi.org/10.1182/blood-2025-353

Published: 2025

Journal Articles

Multiomic Profiling Reveals Pleiotropic Effects of Somatic IRF4-C99R Mutations in Primary Mediastinal Large B-Cell Lymphomas

Blood (2024) 144 (Supplement 1): 2966.

https://doi.org/10.1182/blood-2024-199227

Published: 2024

Journal Articles

A Novel Genetics-Based Classification of Advanced Follicular Lymphoma Identifies Prognostic Subgroups Following Bendamustine-Rituximab Immunochemotherapy

Haya Shaalan, Fabian Frontzek, Ciare Louise Freeman, Andrew Lytle, Pedro Farinha, Waleed Alduaij, Susana Ben-Neriah, Merrill Boyle, Barbara Meissner, Andrew P. Weng, Laurie H. Sehn, Christian Steidl, Laura Hilton, David W. Scott, Ryan Morin

Blood (2024) 144 (Supplement 1): 742.

https://doi.org/10.1182/blood-2024-204219

Published: 2024

Journal Articles

The Fusion Landscape of Anaplastic Large Cell Lymphoma: An L.L.M.P.P. Study

Andrew L. Feldman, Guangzhen Hu, Surendra Dasari, Lisa M. Rimsza, David W. Scott, Jimena B. Gimenez, Farah M. Salama, Min Shi, Elías Campo, Wing Chung Chan, James R. Cook, Giorgio Inghirami, Elaine S. Jaffe, Ryan Morin, Phillipp W. Raess, Andreas Rosenwald, Kerry J. Savage, Louis M. Staudt, George W. Wright, Catalina Amador, Jan Delabie, Timothy C. Greiner, Javeed Iqbal, Laura K. Hilton, Sarah L. Ondrejka, German Ott, Stefania Pittaluga, Graham W. Slack, Susan L. Slager, Joo Y. Song, Hao-Wei Wang, Ahmed A. Aljudi, Stephen M. Ansell, Carlos Barrionuevo, James R. Cerhan, Jennifer R. Chapman-Fredricks, Weina Chen, Laurence de Leval, Alejandro A. Gru, David L. Jaye, Liuyan Jiang, Brad S. Kahl, Kennosuke Karube, Young Hyeh Ko, Eric Mou, Matthew J. Maurer, L. Jeffrey Medeiros, Roberto N. Miranda, Naoki Oishi, Perry M. Anamarija, Akira Satou, Xueju Wang, Ryan A. Wilcox, Xiaojun Wu, Tadashi Yoshino, Yu Zeng

Blood (2024) 144 (Supplement 1): 2974.

https://doi.org/10.1182/blood-2024-202410

Published: 2024

Journal Articles

Biological and Prognostic Subgroups of Plasmablastic Lymphoma Defined By EBV Status and MYC Rearrangement- an L.L.M.P.P. Study

Blood (2024) 144 (Supplement 1): 231.

https://doi.org/10.1182/blood-2024-208880

Published: 2024

Journal Articles

Hnrnpu mutations Are Haploinsufficient and Alter the Transcriptome of MYC-Driven Lymphomas

Qurat Ul Ain Qureshi, Krysta Mila Coyle, Nicole Thomas, Brett Collinge, Kostiantyn Dreval, Laura Hilton, Jasper Wong, David W. Scott, Timothy Audas, Ryan Morin

Blood (2023) 142 (Supplement 1): 1399.

https://doi.org/10.1182/blood-2023-190409

Published: 2023

Journal Articles

Oligomannose-Type Glycans in the Antigen Binding Site Identify Origin and Prognosis of Diffuse Large B Cell Lymphoma

Dylan J. Tatterton, Benjamin Sale, Joel Allen, Maddy L. Newby, Giorgia Chiodin, Patrick J. Duriez, John Butler, Katy J. McCann, David W. Scott, Ryan Morin, Andrew S. Davies, Dean J. Bryant, Freda K. Stevenson, Max Crispin, Francesco Forconi

Blood (2023) 142 (Supplement 1): 428.

https://doi.org/10.1182/blood-2023-188721

Published: 2023

Journal Articles

Early Identification of Refractory/Relapsed Diffuse Large B Cell Lymphoma with Serial Ctdna Sampling

Ryan N Rys, Elie Ritch, Christopher Rushton, Abdelrahman Ahmed, Eugene Brailovski, Christian Steidl, David W. Scott, Ryan Morin, Nathalie A. Johnson

Blood (2023) 142 (Supplement 1): 2996.

https://doi.org/10.1182/blood-2023-190649

Published: 2023

Journal Articles

BTG2 Super-Enhancer Mutations Disrupt TFAP4 Binding and Deregulate BTG2 Expression in Diffuse Large B-Cell Lymphoma

Pantaleo De Simone, Elodie Bal, Antony Holmes, Laura Hilton, Katia Basso, Rajesh K Soni, Ryan Morin, Riccardo Dalla-Favera, Laura Pasqualucci

Blood (2023) 142 (Supplement 1): 523.

https://doi.org/10.1182/blood-2023-190230

Published: 2023

Journal Articles

Large-Scale Genomic Analysis of Mutational Hotspots in Burkitt Lymphoma and Diffuse Large B-Cell Lymphoma

Manuela Cruz, Kostiantyn Dreval, Prasath Pararajalingam, Laura Hilton, Jasper Wong, Christopher Rushton, Ryan Morin

Blood (2023) 142 (Supplement 1): 2992.

https://doi.org/10.1182/blood-2023-185914

Published: 2023

Journal Articles

Pediatric-type nodal follicular lymphoma: a biologically distinct lymphoma with frequent MAPK pathway mutations

Blood (2016) 128 (8): 1093–1100.

https://doi.org/10.1182/blood-2015-12-682591

Published: 2016

Includes: Supplemental data

Journal Articles

A Randomized, Phase II Study with Biomarker Analysis of Panobinostat with or without Rituximab in Relapsed Diffuse Large B Cell Lymphoma

Sarit Assouline, Michael Crump, MD, Torsten Holm Nielsen, Miguel Alcaide, B. Sc., Ph. D., David Macdonald, MD FRCPC, Axel Tosikyan, Tina Haliotis, Celia Greenwood, Kathleen Klein Oros, Ryan Morin, PhD, Nathalie Johnson, MD PhD, Koren Kathleen Mann, PhD

Blood (2015) 126 (23): 2719.

https://doi.org/10.1182/blood.V126.23.2719.2719

Published: 2015

Journal Articles

Comprehensive MYC and BCL2 Genetic Profiling in De Novo Diffuse Large B-Cell Lymphoma Demonstrates Clinically Relevant Genetic Alterations According to Cell of Origin Subtype

Daisuke Ennishi, MD PhD, Anja Mottok, MD, Kerry J. Savage, MDMSc, Susana Ben-Neriah, Hennady Shulha, Pedro Farinha, MD, Fong Chun Chan, MSc, Barbara Meissner, Merrill Boyle, BSc, Christoffer E Hother, MD PhD, Robert Kridel, MD MPH, Ryan Morin, PhD, Marco A Marra, PhD, Laurie H. Sehn, Christian Steidl, MD, Joseph M. Connors, MD, David W Scott, MBChB, PhD, Randy D. Gascoyne

Blood (2015) 126 (23): 109.

https://doi.org/10.1182/blood.V126.23.109.109

Published: 2015

Journal Articles

Genetic Alterations of Gα13 Signaling Pathway with BCL2 over-Expression Confers Lymphoma Dissemination and Inferior Outcome in Germinal Center B Cell Diffuse Large B Cell Lymphoma

Daisuke Ennishi, MD PhD, Anja Mottok, MD, Hennady Shulha, Pedro Farinha, MD, Fong Chun Chan, MSc, Barbara Meissner, Merrill Boyle, BSc, Susana Ben-Neriah, Christoffer E Hother, MD PhD, Robert Kridel, MD MPH, Ryan Morin, PhD, Marco A Marra, PhD, Kerry J. Savage, MDMSc, Laurie H. Sehn, Joseph M. Connors, MD, Christian Steidl, MD, David W Scott, MBChB, PhD, Randy D. Gascoyne

Blood (2015) 126 (23): 111.

https://doi.org/10.1182/blood.V126.23.111.111

Published: 2015

Journal Articles

Genome-wide identification of human microRNAs located in leukemia-associated genomic alterations

Daniel T. Starczynowski, Ryan Morin, Andrew McPherson, Jeff Lam, Raj Chari, Joanna Wegrzyn, Florian Kuchenbauer, Martin Hirst, Kaoru Tohyama, R. Keith Humphries, Wan L. Lam, Marco Marra, Aly Karsan

Blood (2011) 117 (2): 595–607.

https://doi.org/10.1182/blood-2010-03-277012

Published: 2011

Includes: Supplemental data

Journal Articles

Next Generation Transcriptomic Resequencing Identifies Novel Genetic Alterations in High-Risk (HR) Childhood Acute Lymphoblastic Leukemia (ALL): A Report From the Children's Oncology Group (COG) HR ALL TARGET Project.

Blood (2009) 114 (22): 704.

https://doi.org/10.1182/blood.V114.22.704.704

Published: 2009

Journal Articles

Tyrosine 641 of the EZH2 Oncogene Is Frequently Mutated in Follicular and Diffuse Large B-Cell Lymphomas of Germinal Center Origin.

Blood (2009) 114 (22): 139.

https://doi.org/10.1182/blood.V114.22.139.139

Published: 2009

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Gene expression profiling reveals two overarching types of ALCL with distinct targetable biology: an LLMPP study

Evaluating targeted long-read sequencing as a diagnostic tool for burkitt lymphoma

Spen loss drives extra-follicular diffuse large B cell lymphoma with female-specific lethality and TLR pathway therapeutic vulnerabilities

Integrated multi-omic profiling reveals two biologically distinct subgroups of splenic marginal zone lymphoma with prognostic relevance

Multiomic Profiling Reveals Pleiotropic Effects of Somatic IRF4-C99R Mutations in Primary Mediastinal Large B-Cell Lymphomas

A Novel Genetics-Based Classification of Advanced Follicular Lymphoma Identifies Prognostic Subgroups Following Bendamustine-Rituximab Immunochemotherapy

The Fusion Landscape of Anaplastic Large Cell Lymphoma: An L.L.M.P.P. Study

Biological and Prognostic Subgroups of Plasmablastic Lymphoma Defined By EBV Status and MYC Rearrangement- an L.L.M.P.P. Study

Hnrnpu mutations Are Haploinsufficient and Alter the Transcriptome of MYC-Driven Lymphomas

Oligomannose-Type Glycans in the Antigen Binding Site Identify Origin and Prognosis of Diffuse Large B Cell Lymphoma

Early Identification of Refractory/Relapsed Diffuse Large B Cell Lymphoma with Serial Ctdna Sampling

BTG2 Super-Enhancer Mutations Disrupt TFAP4 Binding and Deregulate BTG2 Expression in Diffuse Large B-Cell Lymphoma

Large-Scale Genomic Analysis of Mutational Hotspots in Burkitt Lymphoma and Diffuse Large B-Cell Lymphoma

Pediatric-type nodal follicular lymphoma: a biologically distinct lymphoma with frequent MAPK pathway mutations

A Randomized, Phase II Study with Biomarker Analysis of Panobinostat with or without Rituximab in Relapsed Diffuse Large B Cell Lymphoma

Comprehensive MYC and BCL2 Genetic Profiling in De Novo Diffuse Large B-Cell Lymphoma Demonstrates Clinically Relevant Genetic Alterations According to Cell of Origin Subtype

Genetic Alterations of Gα13 Signaling Pathway with BCL2 over-Expression Confers Lymphoma Dissemination and Inferior Outcome in Germinal Center B Cell Diffuse Large B Cell Lymphoma

Genome-wide identification of human microRNAs located in leukemia-associated genomic alterations

Next Generation Transcriptomic Resequencing Identifies Novel Genetic Alterations in High-Risk (HR) Childhood Acute Lymphoblastic Leukemia (ALL): A Report From the Children's Oncology Group (COG) HR ALL TARGET Project.

Tyrosine 641 of the EZH2 Oncogene Is Frequently Mutated in Follicular and Diffuse Large B-Cell Lymphomas of Germinal Center Origin.

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