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Journal Articles

Drivers of crizotinib resistance in ALK + ALCL

Guangzhen Hu, Andrew L. Feldman
Journal: Blood
Blood (2020) 136 (14): 1573–1575.
https://doi.org/10.1182/blood.2020007226
Published: 2020
Journal Articles

Recurrent MSC E116K mutations in ALK-negative anaplastic large cell lymphoma

Rebecca A. Luchtel, Michael T. Zimmermann, Guangzhen Hu, Surendra Dasari, Manli Jiang, Naoki Oishi, Hailey K. Jacobs, Yu Zeng, Tanya Hundal, Karen L. Rech, Rhett P. Ketterling, Jeong-Heon Lee, Bruce W. Eckloff, Huihuang Yan, Krutika S. Gaonkar, Shulan Tian, Zhenqing Ye, Marshall E. Kadin, Jagmohan Sidhu, Liuyan Jiang, Jesse Voss, Brian K. Link, Sergei I. Syrbu, Fabio Facchetti, N. Nora Bennani, Susan L. Slager, Tamas Ordog, Jean-Pierre Kocher, James R. Cerhan, Stephen M. Ansell, Andrew L. Feldman
Journal: Blood
Blood (2019) 133 (26): 2776–2789.
https://doi.org/10.1182/blood.2019000626
Published: 2019
Includes: Supplemental data
Journal Articles

Molecular profiling reveals immunogenic cues in anaplastic large cell lymphomas with DUSP22 rearrangements

Rebecca A. Luchtel, Surendra Dasari, Naoki Oishi, Martin Bjerregård Pedersen, Guangzhen Hu, Karen L. Rech, Rhett P. Ketterling, Jagmohan Sidhu, Xueju Wang, Ryohei Katoh, Ahmet Dogan, N. Sertac Kip, Julie M. Cunningham, Zhifu Sun, Saurabh Baheti, Julie C. Porcher, Jonathan W. Said, Liuyan Jiang, Stephen Jacques Hamilton-Dutoit, Michael Boe Møller, Peter Nørgaard, N. Nora Bennani, Wee-Joo Chng, Gaofeng Huang, Brian K. Link, Fabio Facchetti, James R. Cerhan, Francesco d’Amore, Stephen M. Ansell, Andrew L. Feldman
Journal: Blood
Blood (2018) 132 (13): 1386–1398.
https://doi.org/10.1182/blood-2018-03-838524
Published: 2018
Includes: Supplemental data
Journal Articles

Recurrent STAT3-JAK2 fusions in indolent T-cell lymphoproliferative disorder of the gastrointestinal tract

Ayush Sharma, Naoki Oishi, Rebecca L. Boddicker, Guangzhen Hu, Hailey K. Benson, Rhett P. Ketterling, Patricia T. Greipp, Darlene L. Knutson, Sara M. Kloft-Nelson, Rong He, Bruce W. Eckloff, Jin Jen, Asha A. Nair, Jaime I. Davila, Surendra Dasari, Konstantinos N. Lazaridis, N. Nora Bennani, Tsung-Teh Wu, Grzegorz S. Nowakowski, Joseph A. Murray, Andrew L. Feldman
Journal: Blood
Blood (2018) 131 (20): 2262–2266.
https://doi.org/10.1182/blood-2018-01-830968
Published: 2018
Journal Articles

DUSP22 Rearrangements Identify a Molecularly Distinct Type of Anaplastic Large Cell Lymphoma Characterized By DNA Hypomethylation and Lack of Activated STAT3

Rebecca Boddicker, PhD, Surendra Dasari, PhD, Naoki Oishi, MD PhD, Guangzhen Hu, PhD, Jagmohan Sidhu, MD, Julie Cunningham, PhD, Zhifu Sun, MD, Saurabh Baheti, MS, Julie C Porcher, Stephen M Ansell, MD PhD, Nabila Nora Bennani, MD, James R. Cerhan, MD PhD, Andrew L Feldman, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1456.
https://doi.org/10.1182/blood.V130.Suppl_1.1456.1456
Published: 2017
Journal Articles

Integrated mate-pair and RNA sequencing identifies novel, targetable gene fusions in peripheral T-cell lymphoma

Clinical Trials & Observations
Rebecca L. Boddicker, Gina L. Razidlo, Surendra Dasari, Yu Zeng, Guangzhen Hu, Ryan A. Knudson, Patricia T. Greipp, Jaime I. Davila, Sarah H. Johnson, Julie C. Porcher, James B. Smadbeck, Bruce W. Eckloff, Daniel D. Billadeau, Paul J. Kurtin, Mark A. McNiven, Brian K. Link, Stephen M. Ansell, James R. Cerhan, Yan W. Asmann, George Vasmatzis, Andrew L. Feldman
Journal: Blood
Blood (2016) 128 (9): 1234–1245.
https://doi.org/10.1182/blood-2016-03-707141
Published: 2016
Includes: Supplemental data
Journal Articles

Loss-of-Function Missense Mutations in Tyrosine Phosphatase PTPN6 Deregulate STAT3 Signaling in Diffuse Large B-Cell Lymphoma

Christos Demosthenous, Guangzhen Hu, PhD, Thomas E Witzig, MD, Mamta Gupta, PhD
Journal: Blood
Blood (2014) 124 (21): 707.
https://doi.org/10.1182/blood.V124.21.707.707
Published: 2014
Journal Articles

Mantle Cell Lymphoma Associated Long Non-Coding RNAs Regulate Polycomb Repressive Complex-2

Guangzhen Hu, PhD, Asha Nair, M.S, Tammy Price-Troska, B.S, Eric D Wieben, PhD, Mamta Gupta, PhD
Journal: Blood
Blood (2014) 124 (21): 140.
https://doi.org/10.1182/blood.V124.21.140.140
Published: 2014
Journal Articles

SHP1 Suppression In Diffuse Large B Cell Lymphoma Is Regulated Through Promoter Hypermethylation At Novel CpG2 Island and H3K27 Trimethylation Histone Mark

Mamta Gupta, Ph.D, Guangzhen Hu, Linda E Wellik, Jing Jing Han, Mary Stenson, B.S, Ahmet Dogan, MD, PhD, Thomas E Witzig, MD
Journal: Blood
Blood (2013) 122 (21): 632.
https://doi.org/10.1182/blood.V122.21.632.632
Published: 2013
Journal Articles

A Novel Long Non-Coding RNA, SNHG4 Complex With Eukaryotic Initiation Factor-4E and Regulate Aberrant Protein Translation In Mantle Cell Lymphoma: Implications For Novel Biomarker

Guangzhen Hu, Thomas E Witzig, MD, Mamta Gupta, Ph.D
Journal: Blood
Blood (2013) 122 (21): 81.
https://doi.org/10.1182/blood.V122.21.81.81
Published: 2013
Journal Articles

A Novel STAT3 mutation Associated with Diffuse Large B Cell Lymphoma Deregulates STAT3 Signaling.

Guangzhen Hu, Thomas E. Witzig, MD, Mamta Gupta, Ph.D
Journal: Blood
Blood (2012) 120 (21): 2690.
https://doi.org/10.1182/blood.V120.21.2690.2690
Published: 2012
Journal Articles

Expression but Not Promoter Hypermethylation of the Tyrosine Phosphatase PTPN6 Is Associated with Activated STAT3 and Inferior Prognosis in Diffuse Large B Cell Lymphoma Molecular Subtypes.

Mamta Gupta, Ph.D, Guangzhen Hu, Steven Offer, Matthew J Maurer, MS, Linda Wellik, Jing Jing Han, Ahmet Dogan, MD, PhD, Robert B. Diasio, MD, Thomas E. Witzig, MD
Journal: Blood
Blood (2012) 120 (21): 2655.
https://doi.org/10.1182/blood.V120.21.2655.2655
Published: 2012
Journal Articles

Elevated serum IL-10 levels in diffuse large B-cell lymphoma: a mechanism of aberrant JAK2 activation

Mamta Gupta, Jing Jing Han, Mary Stenson, Matthew Maurer, Linda Wellik, Guangzhen Hu, Steve Ziesmer, Ahmet Dogan, Thomas E. Witzig
Journal: Blood
Blood (2012) 119 (12): 2844–2853.
https://doi.org/10.1182/blood-2011-10-388538
Published: 2012
Includes: Supplemental data