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Journal Articles

The Expression of Chromosome Region Maintenance Protein 1 (CRM1) in Large Cell Lymphoma

Jithma P. Abeykoon, MD, Paul J. Hampel, MD, Rebecca L. King, MD, Adam J Wood, MD, Melissa C. Larson, MD, Kevin E. Nowakowski, Saurabh Zanwar, MDMBBS, Aishwarya Ravindran, MBBS, Matthew J. Maurer, MS, Linda Wellik, Jonas Paludo, MD, Brian K. Link, MD, James R. Cerhan, MD PhD, Xiaosheng Wu, MD, Thomas M. Habermann, MD, Thomas E. Witzig, MD

Blood (2020) 136 (Supplement 1): 39–40.

https://doi.org/10.1182/blood-2020-138628

Published: 2020

Journal Articles

Targeting glycogen synthase kinase 3 for therapeutic benefit in lymphoma

Xiaosheng Wu, Mary Stenson, Jithma Abeykoon, Kevin Nowakowski, Lianwen Zhang, Joshua Lawson, Linda Wellik, Ying Li, Jordan Krull, Kerstin Wenzl, Anne J. Novak, Stephen M. Ansell, Gail A. Bishop, Daniel D. Billadeau, Kah Whye Peng, Francis Giles, Daniel M. Schmitt, Thomas E. Witzig

Blood (2019) 134 (4): 363–373.

https://doi.org/10.1182/blood.2018874560

Published: 2019

Includes: Supplemental data

Journal Articles

Expression of MYC but Not pSTAT3 Is an Adverse Prognostic Factor for Diffuse Large B Cell Lymphoma (DLBCL) Treated with Epratuzumab/R-CHOP

Mamta Gupta, Ph.D, Matthew J Maurer, MS, Linda Wellik, Mark E Law, Jing Jing Han, Ivana N. Micallef, MD, Ahmet Dogan, MD, PhD, Thomas E. Witzig, MD

Blood (2012) 120 (21): 1575.

https://doi.org/10.1182/blood.V120.21.1575.1575

Published: 2012

Journal Articles

Expression but Not Promoter Hypermethylation of the Tyrosine Phosphatase PTPN6 Is Associated with Activated STAT3 and Inferior Prognosis in Diffuse Large B Cell Lymphoma Molecular Subtypes.

Mamta Gupta, Ph.D, Guangzhen Hu, Steven Offer, Matthew J Maurer, MS, Linda Wellik, Jing Jing Han, Ahmet Dogan, MD, PhD, Robert B. Diasio, MD, Thomas E. Witzig, MD

Blood (2012) 120 (21): 2655.

https://doi.org/10.1182/blood.V120.21.2655.2655

Published: 2012

Journal Articles

Elevated serum IL-10 levels in diffuse large B-cell lymphoma: a mechanism of aberrant JAK2 activation

Mamta Gupta, Jing Jing Han, Mary Stenson, Matthew Maurer, Linda Wellik, Guangzhen Hu, Steve Ziesmer, Ahmet Dogan, Thomas E. Witzig

Blood (2012) 119 (12): 2844–2853.

https://doi.org/10.1182/blood-2011-10-388538

Published: 2012

Includes: Supplemental data

Journal Articles

Elevated Serum IL-10 Levels in Patients with Diffuse Large B Cell Lymphoma: A Mechanism of Aberrant JAK2 Kinase Activation

Mamta Gupta, Ph.D, Mary Stenson, Jing Jing Han, Matthew J Maurer, MS, Linda Wellik, Steven C. Ziesmer, Ahmet Dogan, Thomas E. Witzig, MD

Blood (2011) 118 (21): 960.

https://doi.org/10.1182/blood.V118.21.960.960

Published: 2011

Journal Articles

Examining Measures of Proliferation for Use in Risk Stratification of Myeloma

Mark R.E. Coyne, MBBCh, BAO, MRCPI, Linda Wellik, Esteban Braggio, PhD, Michael E O'Dwyer, MD, FRCPI, FRCPath, Corrado Santocanale, PhD, Riccardo Valdez, MD, P.Leif Bergsagel, MD, Marta Chesi

Blood (2011) 118 (21): 5093.

https://doi.org/10.1182/blood.V118.21.5093.5093

Published: 2011

Journal Articles

Silencing of SHP1 Is Frequent in Phospho-STAT3 Positive Diffuse Large Cell Lymphoma and This Silencing Is Independent of Methylation of Cpg Islands,

Mamta Gupta, Ph.D, Gaungzhen Hu, Linda Wellik, Steven Offer, Robert B. Diasio, MD, Ahmet Dogan, Thomas E. Witzig, MD

Blood (2011) 118 (21): 3678.

https://doi.org/10.1182/blood.V118.21.3678.3678

Published: 2011

Journal Articles

Dual Inhibition of mTORC1/mTORC2 Induces Apoptosis of Mantle Cell Lymphoma by Preventing Rictor Mediated AKT S473 Phosphorylation by Potentiating AKT2-PHLPP1 Association

Mamta Gupta, Ph.D, Andrea Wahner Hendrickson, Jing Jing Han, Mary Stenson, Linda Wellik, Sharon Barr, Scott H. Kaufmann, MD, PhD, Thomas E. Witzig, MD

Blood (2010) 116 (21): 772.

https://doi.org/10.1182/blood.V116.21.772.772

Published: 2010

Journal Articles

GATA-3 or T-Bet Expression In PTCL-U Identify High-Risk Patients with Poor Outcomes and Distinct Clinical Characteristics Suggesting Their Derivation From Specific Subsets of T Helper Cells

Ryan A. Wilcox, MD, PhD, Andrew L Feldman, MD, Kay Ristow, Thomas M. Habermann, MD, Steven Ziesmer, Linda Wellik, Thomas E. Witzig, MD, Stephen M. Ansell, MD, PhD

Blood (2010) 116 (21): 4125.

https://doi.org/10.1182/blood.V116.21.4125.4125

Published: 2010

Journal Articles

HDAC Class I Inhibition Acetylates a Non-Histone Protein STAT3 by Modulating p300-STAT3-HDAC1 Interaction In Activated B- Cell Like (ABC) Diffuse Large B Cell Lymphoma

Mamta Gupta, Ph.D, Jing Jing Han, Mary Stenson, Linda Wellik, Thomas E. Witzig, MD

Blood (2010) 116 (21): 115.

https://doi.org/10.1182/blood.V116.21.115.115

Published: 2010

Journal Articles

Mechanism of Action of a Novel c-Met Inhibitor MK2461 In Multiple Myeloma

Vijay G. Ramakrishnan, PhD, Teresa Kimlinger, Jessica Haug, Timothy Halling, Linda Wellik, S. Vincent Rajkumar, MD, Shaji Kumar, MD

Blood (2010) 116 (21): 4078.

https://doi.org/10.1182/blood.V116.21.4078.4078

Published: 2010

Journal Articles

Significant In Vitro Activity of a Novel Inhibitor of Apoptosis (IAP) Inhibitor LC161 In Multiple Myeloma

Jessica Haug, Vijay G. Ramakrishnan, PhD, Teresa Kimlinger, Timothy Halling, Linda Wellik, S. Vincent Rajkumar, MD, Shaji Kumar, MD

Blood (2010) 116 (21): 2998.

https://doi.org/10.1182/blood.V116.21.2998.2998

Published: 2010

Journal Articles

Significant in-Vitro Activity of a Novel JAK2 Inhibitor in Multiple Myeloma Associated with Preferential Cytotoxicity for CD45+ Myeloma Cells.

Vijay Ramakrishnan, PhD, Jessica Haug, Teresa Kimlinger, Timothy Halling, Linda Wellik, Animesh D. Pardanani, MBBS, PhD, Ayalew Tefferi, MD, S. Vincent Rajkumar, MD, Shaji Kumar, MD

Blood (2009) 114 (22): 2848.

https://doi.org/10.1182/blood.V114.22.2848.2848

Published: 2009

Journal Articles

Aberrant Regulation of pVHL Levels by Microrna May Explain Autocrine Secretion of VEGF in CLL B Cells.

Asish K Ghosh, PhD, Tait Shanafelt, MD, George A Calin, MD, PhD, Carlo M. Croce, MD, Linda Wellik, Debabrata Mukhopadhyay, Neil Kay

Blood (2008) 112 (11): 1064.

https://doi.org/10.1182/blood.V112.11.1064.1064

Published: 2008

Journal Articles

Epigallocatechin-3-Gallate (EGCG), a Polyphenol Extracted from Green Tea, Has Significant In Vitro Activity Against Myeloma Cells.

Shaji Kumar, MD, Michael M. Timm, Jessica L. Haug, Teresa K. Kimlinger, Linda Wellik, Michael P. Kline, Ph.D, S. Vincent Rajkumar, MD

Blood (2006) 108 (11): 3465.

https://doi.org/10.1182/blood.V108.11.3465.3465

Published: 2006

Journal Articles

Thymoglobulin (Polyclonal Rabbit Anti Thymocyte Globulin) Has In Vivo Activity in a Mouse Model of Myeloma.

Michael Timm, Linda Wellik, Teresa Kimlinger, Jessica Haug, Michael Kline, Ph.D, S. Vincent Rajkumar, MD, Philip Greipp, MD, Shaji Kumar, MD

Blood (2006) 108 (11): 3487.

https://doi.org/10.1182/blood.V108.11.3487.3487

Published: 2006

Journal Articles

Induction of Vascular Endothelial Growth Factor (VEGF) and Interleukin 6 (IL-6) in Stromal Cells by Plasma Cells from Different Stages of Myeloma.

Jessica L. Haug, S. Vincent Rajkumar, MD, John A. Lust, MD, Thomas E. Witzig, MD, Teresa K. Kimlinger, Michael M. Timm, Michael P. Kline, Ph.D, Linda Wellik, Shaji Kumar, MD

Blood (2006) 108 (11): 5065.

https://doi.org/10.1182/blood.V108.11.5065.5065

Published: 2006

Journal Articles

Expression of CD126 (IL-R alpha) on Plasma Cells in Monoclonal Gammopathies.

Syed T. Mahmood, MD, Shaji Kumar, MD, Teresa K. Kimlinger, Jessica L. Haug, Michael Timm, Linda Wellik, Michael Kline, Ph.D, S. Vincent Rajkumar, MD

Blood (2006) 108 (11): 5066.

https://doi.org/10.1182/blood.V108.11.5066.5066

Published: 2006

Journal Articles

Identification of Genes Associated with Increased Bone Marrow Angiogenesis in Multiple Myeloma.

Michael Kline, PhD, S. Vincent Rajkumar, MD, Jessica Haug, Linda Wellik, John A. Lust, MD, PhD, Rafael Fonseca, MD, Philip R. Greipp, MD, Shaji Kumar, MD

Blood (2005) 106 (11): 5109.

https://doi.org/10.1182/blood.V106.11.5109.5109

Published: 2005

NARROW

The Expression of Chromosome Region Maintenance Protein 1 (CRM1) in Large Cell Lymphoma

Targeting glycogen synthase kinase 3 for therapeutic benefit in lymphoma

Expression of MYC but Not pSTAT3 Is an Adverse Prognostic Factor for Diffuse Large B Cell Lymphoma (DLBCL) Treated with Epratuzumab/R-CHOP

Expression but Not Promoter Hypermethylation of the Tyrosine Phosphatase PTPN6 Is Associated with Activated STAT3 and Inferior Prognosis in Diffuse Large B Cell Lymphoma Molecular Subtypes.

Elevated serum IL-10 levels in diffuse large B-cell lymphoma: a mechanism of aberrant JAK2 activation

Elevated Serum IL-10 Levels in Patients with Diffuse Large B Cell Lymphoma: A Mechanism of Aberrant JAK2 Kinase Activation

Examining Measures of Proliferation for Use in Risk Stratification of Myeloma

Silencing of SHP1 Is Frequent in Phospho-STAT3 Positive Diffuse Large Cell Lymphoma and This Silencing Is Independent of Methylation of Cpg Islands,

Dual Inhibition of mTORC1/mTORC2 Induces Apoptosis of Mantle Cell Lymphoma by Preventing Rictor Mediated AKT S473 Phosphorylation by Potentiating AKT2-PHLPP1 Association

GATA-3 or T-Bet Expression In PTCL-U Identify High-Risk Patients with Poor Outcomes and Distinct Clinical Characteristics Suggesting Their Derivation From Specific Subsets of T Helper Cells

HDAC Class I Inhibition Acetylates a Non-Histone Protein STAT3 by Modulating p300-STAT3-HDAC1 Interaction In Activated B- Cell Like (ABC) Diffuse Large B Cell Lymphoma

Mechanism of Action of a Novel c-Met Inhibitor MK2461 In Multiple Myeloma

Significant In Vitro Activity of a Novel Inhibitor of Apoptosis (IAP) Inhibitor LC161 In Multiple Myeloma

Significant in-Vitro Activity of a Novel JAK2 Inhibitor in Multiple Myeloma Associated with Preferential Cytotoxicity for CD45+ Myeloma Cells.

Aberrant Regulation of pVHL Levels by Microrna May Explain Autocrine Secretion of VEGF in CLL B Cells.

Epigallocatechin-3-Gallate (EGCG), a Polyphenol Extracted from Green Tea, Has Significant In Vitro Activity Against Myeloma Cells.

Thymoglobulin (Polyclonal Rabbit Anti Thymocyte Globulin) Has In Vivo Activity in a Mouse Model of Myeloma.

Induction of Vascular Endothelial Growth Factor (VEGF) and Interleukin 6 (IL-6) in Stromal Cells by Plasma Cells from Different Stages of Myeloma.

Expression of CD126 (IL-R alpha) on Plasma Cells in Monoclonal Gammopathies.

Identification of Genes Associated with Increased Bone Marrow Angiogenesis in Multiple Myeloma.

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American Society of Hematology

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American Society of Hematology

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