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David W. Scott
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Journal Articles

CNS Relapse in High-Grade B-cell Lymphoma with MYC and BCL2 Rearrangements and Dark-Zone Signature-Expressing DLBCL

Clinical Trials & Observations
Waleed Alduaij, Aixiang Jiang, Diego Villa, Brett J Collinge, Susana Ben-Neriah, Merrill Boyle, Barbara Meissner, Laura K Hilton, Pedro Farinha, Graham W. Slack, Jeffrey W Craig, Alina S. Gerrie, Ciara L Freeman, Andrew J Mungall, Christian Steidl, Laurie H. Sehn, David W. Scott, Kerry J. Savage
Journal: Blood
Blood blood.2024025725.
https://doi.org/10.1182/blood.2024025725
Published: 2024
Includes: Supplemental data
Journal Articles

Unbalanced MYC break-apart FISH patterns indicate the presence of a MYC rearrangement in HGBCL-DH- BCL2

Brief Report
Brett Collinge, Susana Ben-Neriah, Laura K. Hilton, Waleed Alduaij, Tracy Tucker, Graham W. Slack, Pedro Farinha, Jeffrey W. Craig, Merrill Boyle, Barbara Meissner, Diego Villa, Alina S. Gerrie, Laurie H. Sehn, Kerry J. Savage, Ryan D. Morin, Andrew J. Mungall, Christian Steidl, David W. Scott
Journal: Blood
Blood (2024) 144 (15): 1611–1616.
https://doi.org/10.1182/blood.2024025603
Published: 2024
Includes: Supplemental data
Journal Articles

Motive and opportunity: MYC rearrangements in high-grade B-cell lymphoma with MYC and BCL2 rearrangements (an LLMPP study)

Laura K. Hilton, Brett Collinge, Susana Ben-Neriah, Waleed Alduaij, Haya Shaalan, Andrew P. Weng, Manuela Cruz, Graham W. Slack, Pedro Farinha, Tomoko Miyata-Takata, Merrill Boyle, Barbara Meissner, James R. Cook, Sarah L. Ondrejka, German Ott, Andreas Rosenwald, Elias Campo, Catalina Amador, Timothy C. Greiner, Philipp W. Raess, Joo Y. Song, Giorgio Inghirami, Elaine S. Jaffe, Dennis D. Weisenburger, Wing C. Chan, Klaus Beiske, Kai Fu, Jan Delabie, Stefania Pittaluga, Javeed Iqbal, George Wright, Laurie H. Sehn, Kerry J. Savage, Andrew J. Mungall, Andrew L. Feldman, Louis M. Staudt, Christian Steidl, Lisa M. Rimsza, Ryan D. Morin, David W. Scott
Journal: Blood
Blood (2024) 144 (5): 525–540.
https://doi.org/10.1182/blood.2024024251
Published: 2024
Includes: Supplemental data
Journal Articles

Gene Expression Profiling Reveals Two Overarching Types of Anaplastic Large Cell Lymphoma with Distinct Targetable Biology: An L.L.M.P.P. Study

Andrew L. Feldman, Surendra Dasari, Lisa M. Rimsza, David W. Scott, Naoki Oishi, Catalina Amador, Elias Campo, Wing C. Chan, James R. Cook, Jan Delabie, Pedro Farinha, Kai Fu, Timothy C. Greiner, Giorgio Inghirami, Javeed Iqbal, Elaine S. Jaffe, Sarah L. Ondrejka, German Ott, Stefania Pittaluga, Phil Raess, Andreas Rosenwald, Kerry J. Savage, Graham Slack, Susan L. Slager, Joo Y. Song, Louis M. Staudt, George Wright, Hao-Wei Wang, Yu Zeng, Tadashi Yoshino, Xiaojun Wu, Ryan A. Wilcox, Xueju Wang, Akira Satou, Anamarija M. Perry, Roberto Miranda, L. Jeffrey Medeiros, Matthew J. Maurer, Eric Mou, Young Hyeh Ko, Kennosuke Karube, Brad S. Kahl, Liuyan Jiang, David L Jaye, Laurence de Leval, Weina Chen, Jennifer R. Chapman-Fredricks, James R. Cerhan, Carlos Barrionuevo, Stephen M Ansell, Ahmed Aljudi
Journal: Blood
Blood (2023) 142 (Supplement 1): 847.
https://doi.org/10.1182/blood-2023-186969
Published: 2023
Journal Articles

A CD5 Gene Signature Identifies Diffuse Large B-Cell Lymphomas Sensitive to Brutonʼs Tyrosine Kinase Inhibition

Alan Cooper, Sravya Tumuluru, Kyle Kissick, Girish Venkataraman, Joo Y Song, Andrew Lytle, Gerben Duns, Jovian Yu, Nikita Kotlov, Alexander Bagaev, Brendan Paul Hodkinson, Srimathi Srinivasan, Sonali M. Smith, David W. Scott, Christian Steidl, James Godfrey, Justin Kline
Journal: Blood
Blood (2023) 142 (Supplement 1): 851.
https://doi.org/10.1182/blood-2023-182390
Published: 2023
Journal Articles

Multi-Dimensional Molecular and Tumor-Microenvironment Analysis of Classic Hodgkin Lymphoma

Tomohiro Aoki, Gerben Duns, Shinya Rai, Andrew Lytle, Yifan Yin, Clementine Sarkozy, Stacy Hung, Katy Milne, Adele Telenius, Luke O'Brien, Celia Strong, Talia Goodyear, Shaocheng Wu, Katsuyoshi Takata, Tomoko Miyata-Takata, Merrill Boyle, Susana Ben-Neriah, Andrew P. Weng, Andrew Roth, Anca Prica, Robert Kridel, Brad Nelson, Pedro Farinha, Kerry J. Savage, David W. Scott, Christian Steidl
Journal: Blood
Blood (2023) 142 (Supplement 1): 172.
https://doi.org/10.1182/blood-2023-174139
Published: 2023
Journal Articles

Early Identification of Refractory/Relapsed Diffuse Large B Cell Lymphoma with Serial Ctdna Sampling

Ryan N Rys, Elie Ritch, Christopher Rushton, Abdelrahman Ahmed, Eugene Brailovski, Christian Steidl, David W. Scott, Ryan Morin, Nathalie A. Johnson
Journal: Blood
Blood (2023) 142 (Supplement 1): 2996.
https://doi.org/10.1182/blood-2023-190649
Published: 2023
Journal Articles

Results from an Intergroup Randomized Phase II Study of the Combinations of Ipilimumab, Nivolumab and Brentuximab Vedotin in Patients with Relapsed/Refractory Classic Hodgkin Lymphoma: A Trial of the ECOG-ACRIN Research Group (E4412)

Catherine S Diefenbach, Opeyemi Jegede, Stephen M Ansell, Christian Steidl, Yasodha Natkunam, David W. Scott, Neha Mehta-Shah, Jennifer E Amengual, Christopher J. Forlenza, Peter D. Cole, Nancy L. Bartlett, Kevin A. David, Ranjana H. Advani, Richard F. Ambinder, Sachdev Thomas, Sami Ibrahimi, Brad S. Kahl
Journal: Blood
Blood (2023) 142 (Supplement 1): 607.
https://doi.org/10.1182/blood-2023-184531
Published: 2023
Journal Articles

Cooperative Super-Enhancer Inactivation through Loss of Crebbp and KMT2D Skews B Cell Fate Decisions and Yields T Cell-Depleted Lymphomas

Jie Li, Christopher Chin, Hsia-Yuan Ying, Cem Meydan, Matthew Teater, Min Xia, Pedro Farinha, Katsuyoshi Takata, Chi-Shuen Chu, Martin A Rivas, Amy Chadburn, Christian Steidl, David W. Scott, Robert G. Roeder, Christopher Mason, Wendy Béguelin, Ari M Melnick
Journal: Blood
Blood (2023) 142 (Supplement 1): 2776.
https://doi.org/10.1182/blood-2023-174501
Published: 2023
Journal Articles

Oligomannose-Type Glycans in the Antigen Binding Site Identify Origin and Prognosis of Diffuse Large B Cell Lymphoma

Dylan J. Tatterton, Benjamin Sale, Joel Allen, Maddy L. Newby, Giorgia Chiodin, Patrick J. Duriez, John Butler, Katy J. McCann, David W. Scott, Ryan Morin, Andrew S. Davies, Dean J. Bryant, Freda K. Stevenson, Max Crispin, Francesco Forconi
Journal: Blood
Blood (2023) 142 (Supplement 1): 428.
https://doi.org/10.1182/blood-2023-188721
Published: 2023
Journal Articles

SWI/SNF Chromatin Remodeling Complex Orchestrates Sequential Binding of Key Transcription Factors in B Cells and Restricts Aggressive Lymphoma

Darko Barisic, Christopher Chin, Cem Meydan, Matthew Teater, Ioanna Tsialta, Coraline Mlynarczyk, Amy Chadburn, Min Xia, Christian Steidl, David W. Scott, Andrew P. Weng, Christopher Mason, Michael R. Green, Ari M Melnick
Journal: Blood
Blood (2023) 142 (Supplement 1): 718.
https://doi.org/10.1182/blood-2023-190494
Published: 2023
Journal Articles

CD79 Expression Is Associated with Cell-of-Origin and Outcome in Diffuse Large B-Cell Lymphoma

Yusuke Naoi, Ryota Chijimatsu, Tomohiro Urata, Kazutaka Sunami, Toshi Imai, Yuichiro Nawa, Yasushi Hiramatsu, Kazuhiko Yamamoto, Soichiro Fujii, Isao Yoshida, Tomofumi Yano, Kazuhiro Ikeuchi, Hiroki Kobayashi, Katsuma Tani, Hiroyuki Murakami, Hideki Ujiie, Yasuharu Sato, Katsuyoshi Takata, Merrill Boyle, Aixiang Jiang, Yoshinobu Maeda, David W. Scott, Daisuke Ennishi
Journal: Blood
Blood (2023) 142 (Supplement 1): 1760.
https://doi.org/10.1182/blood-2023-172972
Published: 2023
Journal Articles

Hnrnpu mutations Are Haploinsufficient and Alter the Transcriptome of MYC-Driven Lymphomas

Qurat Ul Ain Qureshi, Krysta Mila Coyle, Nicole Thomas, Brett Collinge, Kostiantyn Dreval, Laura Hilton, Jasper Wong, David W. Scott, Timothy Audas, Ryan Morin
Journal: Blood
Blood (2023) 142 (Supplement 1): 1399.
https://doi.org/10.1182/blood-2023-190409
Published: 2023
Journal Articles

Rituximab Combined with Chemotherapy and Acalabrutinib Prior to Autologous Stem Cell Transplantation in Mantle Cell Lymphoma: The Rectangle Trial

Diego Villa, Jean-Francois Larouche, Matthew C. Cheung, Mary-Margaret Keating, Katherine Zukotynski, Petter Tonseth, Samantha Mayo, Robert Laister, David W. Scott, John Kuruvilla
Journal: Blood
Blood (2023) 142 (Supplement 1): 3042.
https://doi.org/10.1182/blood-2023-179375
Published: 2023
Journal Articles

Evaluation of a Prognostic 23-Gene Expression Panel in a Set of 390 Multiethnic Hodgkin Lymphoma Patients

Anthony Colombo, Jia Yin Wan, Aixiang Jiang, Jose Aparicio, Esther Lam, Tomohiro Aoki, Joo Y Song, Sheeja Pullarkat, Chun Chao, Juan Manuel Mejia-Arangure, Brenda Hernandez, Pamela B. Allen, Christopher R. Flowers, Sophia S. Wang, Juanita Evans, Owen Chan, Jakub Svoboda, Anja Mottok, Leon Bernal-Mizrachi, Megan Lim, David W. Scott, Imran Siddiqi, David Conti, Christian Steidl, Wendy Cozen
Journal: Blood
Blood (2023) 142 (Supplement 1): 4379.
https://doi.org/10.1182/blood-2023-182906
Published: 2023
Journal Articles

Identification and Clinical Characterization of CNS Relapse in DLBCL Patients across 19 Prospective Phase 2 and 3 Trials - a GLA/ DSHNHL and LYSA Collaboration

Fabian Frontzek, Loïc Renaud, Ulrich Duehrsen, Viola Poeschel, Sophie Bernard, Loïc Chartier, Nicolas Ketterer, Christian Recher, Olivier Fitoussi, Gerhard Held, Rene-Olivier Casasnovas, Corinne Haioun, Nicolas Mounier, Hervé Tilly, Franck Morschhauser, Steven Le Gouill, Imke E. Karsten, Gerben Duns, Christian Steidl, David W. Scott, Wolfram Klapper, Andreas Rosenwald, German Ott, Thierry Jo Molina, Georg Lenz, Marita Ziepert, Bettina Altmann, Catherine Thieblemont, Norbert Schmitz
Journal: Blood
Blood (2023) 142 (Supplement 1): 71.
https://doi.org/10.1182/blood-2023-178815
Published: 2023
Journal Articles

EBV Prevalence and Overall Survival in the M ulti e thnic S tudy of H odgkin Lymphoma (MESH)

Esther Lam, Jia Yin Wan, Jose Aparicio, Sheeja Pullarkat, Anthony Colombo, Joo Y Song, Chun Chao, Juan Manuel Mejia-Arangure, Brenda Hernandez, Aixiang Jiang, Tomohiro Aoki, Pamela B. Allen, Christopher R. Flowers, Sophia S. Wang, Juanita Evans, Owen Chan, Leon Bernal-Mizrachi, David W. Scott, Megan Lim, Jakub Svoboda, Christian Steidl, Anja Mottok, David Conti, Imran Siddiqi, Wendy Cozen
Journal: Blood
Blood (2023) 142 (Supplement 1): 6188.
https://doi.org/10.1182/blood-2023-182919
Published: 2023
Journal Articles

Genetic subdivisions of follicular lymphoma defined by distinct coding and noncoding mutation patterns

Kostiantyn Dreval, Laura K. Hilton, Manuela Cruz, Haya Shaalan, Susana Ben-Neriah, Merrill Boyle, Brett Collinge, Krysta M. Coyle, Gerben Duns, Pedro Farinha, Bruno M. Grande, Barbara Meissner, Prasath Pararajalingam, Christopher K. Rushton, Graham W. Slack, Jasper Wong, Andrew J. Mungall, Marco A. Marra, Joseph M. Connors, Christian Steidl, David W. Scott, Ryan D. Morin
Journal: Blood
Blood (2023) 142 (6): 561–573.
https://doi.org/10.1182/blood.2022018719
Published: 2023
Includes: Supplemental data
Journal Articles

Molecular determinants of clinical outcomes in a real-world diffuse large B-cell lymphoma population

Clinical Trials & Observations
Waleed Alduaij, Brett Collinge, Susana Ben-Neriah, Aixiang Jiang, Laura K. Hilton, Merrill Boyle, Barbara Meissner, Lauren Chong, Tomoko Miyata-Takata, Graham W. Slack, Pedro Farinha, Jeffrey W. Craig, Andrew Lytle, Kerry J. Savage, Diego Villa, Alina S. Gerrie, Ciara L. Freeman, Randy D. Gascoyne, Joseph M. Connors, Ryan D. Morin, Laurie H. Sehn, Andrew J. Mungall, Christian Steidl, David W. Scott
Journal: Blood
Blood (2023) 141 (20): 2493–2507.
https://doi.org/10.1182/blood.2022018248
Published: 2023
Includes: Supplemental data
Journal Articles

Genetic subgroups inform on pathobiology in adult and pediatric Burkitt lymphoma

Nicole Thomas, Kostiantyn Dreval, Daniela S. Gerhard, Laura K. Hilton, Jeremy S. Abramson, Richard F. Ambinder, Stefan Barta, Nancy L. Bartlett, Jeffrey Bethony, Kishor Bhatia, Jay Bowen, Anthony C. Bryan, Ethel Cesarman, Corey Casper, Amy Chadburn, Manuela Cruz, Dirk P. Dittmer, Maureen A. Dyer, Pedro Farinha, Julie M. Gastier-Foster, Alina S. Gerrie, Bruno M. Grande, Timothy Greiner, Nicholas B. Griner, Thomas G. Gross, Nancy L. Harris, John D. Irvin, Elaine S. Jaffe, David Henry, Rebecca Huppi, Fabio E. Leal, Michael S. Lee, Jean Paul Martin, Marie-Reine Martin, Sam M. Mbulaiteye, Ronald Mitsuyasu, Vivian Morris, Charles G. Mullighan, Andrew J. Mungall, Karen Mungall, Innocent Mutyaba, Mostafa Nokta, Constance Namirembe, Ariela Noy, Martin D. Ogwang, Abraham Omoding, Jackson Orem, German Ott, Hilary Petrello, Stefania Pittaluga, James D. Phelan, Juan Carlos Ramos, Lee Ratner, Steven J. Reynolds, Paul G. Rubinstein, Gerhard Sissolak, Graham Slack, Shaghayegh Soudi, Steven H. Swerdlow, Alexandra Traverse-Glehen, Wyndham H. Wilson, Jasper Wong, Robert Yarchoan, Jean C. ZenKlusen, Marco A. Marra, Louis M. Staudt, David W. Scott, Ryan D. Morin
Journal: Blood
Blood (2023) 141 (8): 904–916.
https://doi.org/10.1182/blood.2022016534
Published: 2023
Includes: Supplemental data