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Journal Articles

Development and Characterization of a Novel Murine Peripheral T-Cell Lymphoma Cell Line Which Closely Mimics Human Disease

Larry Milshteyn, Joseph Lownik, Anton Villamejor, Akil Merchant
Journal: Blood
Blood (2023) 142 (Supplement 1): 3021.
https://doi.org/10.1182/blood-2023-188299
Published: 2023
Journal Articles

Metabolic Reprograming of Exhausted Intratumoral CD8+ T-Cell Underlies Anti-Tumor Activity of Sumoylation Inhibitors in Large B Cell Lymphoma

Joseph Lownik, Larry Milshteyn, Anton Villamejor, Jude Canon, Akil Merchant
Journal: Blood
Blood (2023) 142 (Supplement 1): 3009.
https://doi.org/10.1182/blood-2023-188238
Published: 2023
Journal Articles

Phase 2 Randomized, Open-Label, Multicenter Study to Evaluate the Efficacy and Safety of Plamotamab Combined with Tafasitamab (Tafa) + Lenalidomide (Len) Vs Tafa+Len in Relapsed or Refractory DLBCL

Krish Patel, Youngil Koh, Sabarish Ayyappan, Yasmin Karimi, Izidore S. Lossos, Akil Merchant, Phuong Lee, Jianhua Jin, Raphael Clynes, Jitendra Kanodia, Michael T. Chiarella, Steve Kye, Jean-Marie Michot
Journal: Blood
Blood (2022) 140 (Supplement 1): 12066–12067.
https://doi.org/10.1182/blood-2022-158042
Published: 2022
Journal Articles

Spatial Protein Analysis of the Tumor Microenvironment and Biomarkers in Hodgkin's Lymphoma

Alexander Xu, Tomohiro Aoki, Aixiang Jiang, Alicia Gamboa, Anthony R. Colombo, Christian Steidl, Akil Merchant
Journal: Blood
Blood (2022) 140 (Supplement 1): 3564–3565.
https://doi.org/10.1182/blood-2022-170737
Published: 2022
Journal Articles

Integrative Analysis of Genetic and Tumor Microenvironment Topology to Delineate Prognostic Subtypes in Mantle Cell Lymphoma

Sunandini Sharma, Alyssa C. Bouska, Alicia Gamboa, Roshia Ali, Issa Ismail Issa, Waseem G. Lone, Dylan T. Jochum, Weiwei Zhang, Salma Elhag, Dario Ghersi, Dalia ElGamal, Julie M. Vose, Chengfeng Bi, Akil Merchant, Javeed Iqbal
Journal: Blood
Blood (2022) 140 (Supplement 1): 3601–3602.
https://doi.org/10.1182/blood-2022-169933
Published: 2022
Journal Articles

Spatial Tumor Microenvironment Characterization and Outcome of Relapsed/Refractory Classic Hodgkin Lymphoma

Tomohiro Aoki, Aixiang Jiang, Alexander Xu, Alicia Gamboa, Yifan Yin, Katy Milne, Celia Strong, Talia Goodyear, Shaocheng Wu, Lauren C. Chong, Katsuyoshi Takata, Elizabeth Chavez, Tomoko Miyata-Takata, Anthony R. Colombo, Monirath Hav, Adele Telenius, Susana Ben-Neriah, Andrew P. Weng, Kerry J. Savage, David W. Scott, Andrew Roth, Pedro Farinha, Brad H Nelson, Akil Merchant, Christian Steidl
Journal: Blood
Blood (2022) 140 (Supplement 1): 170–171.
https://doi.org/10.1182/blood-2022-158709
Published: 2022
Journal Articles

A Pilot/Safety Study of sEphB4-Hsa in Combination with a Hypomethylating Agent for Patients with Relapsed or Refractory Myelodysplastic Syndrome and Acute Myeloid Leukemia Previously Treated with a Hypomethylating Agent

Caitlin O'Neill, MD, Akil Merchant, MD, Parkash S. Gill, MD, Casey L. O'Connell, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 40–41.
https://doi.org/10.1182/blood-2020-141340
Published: 2020
Journal Articles

Single Cell Transcriptome Analysis Reveals Disease-Defining T Cell Subsets in the Tumor Microenvironment of Classic Hodgkin Lymphoma

Tomohiro Aoki, MD PhD, Lauren C. Chong, MSc, Katsuyoshi Takata, MD PhD, Katy Milne, Monirath Hav, PhD, Anthony Colombo, MS, Elizabeth Chavez, BSc, Cg RT, Tomoko Miyata-Takata, Vivian Lam, Chanel Ghesquiere, Daniel Kos, Talia Goodyear, Allen W. Zhang, Xuehai Wang, PhD, Saeed Saberi, Jiarui W. Ding, Pedro Farinha, MD PhD, Andrew P. Weng, MD PhD, Kerry J Savage, BSc, MD MSc, David W. Scott, MBChB, PhD, Gerald Krystal, PhD, Brad H. Nelson, Anja Mottok, MD PhD, Akil Merchant, MD, Sohrab P Shah, Christian Steidl, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 547.
https://doi.org/10.1182/blood-2019-121584
Published: 2019
Journal Articles

Highly Multiplexed Single Cell Spatial Analysis of the Tumor Microenvironment in Lymphoma Predicts Clinical Outcomes

Monirath Hav, PhD, Anthony Colombo, MS, Erik Gerdtsson, MS, Mohan Singh, PhD, Denaly Chen, MD, James Hicks, PhD, Peter Kuhn, PhD, Imran Siddiqi, MD PhD, Akil Merchant, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2789.
https://doi.org/10.1182/blood-2019-130831
Published: 2019
Journal Articles

Biomarkers of Overall Survival and Response to Glasdegib and Intensive or Non-Intensive Chemotherapy in Patients with Acute Myeloid Leukemia

Jorge E. Cortes, MD, Akil Merchant, MD, Catriona Jamieson, MD PhD, Daniel A Pollyea, MD, Michael Heuser, MD, Geoffrey Chan, MD, Panpan Wang, Keith A Ching, Jillian Johnson, Thomas O'Brien
Journal: Blood
Blood (2018) 132 (Supplement 1): 2733.
https://doi.org/10.1182/blood-2018-99-111239
Published: 2018
Journal Articles

Highly Multiplexed Imaging Mass Cytometry Allows Visualization of Tumor and Immune Cell Interactions of the Tumor Microenvironment in FFPE Tissue Sections

Mohan Singh, PhD, Parvesh Chaudhry, PhD, Erik Gerdtsson, MS, Asaf Maoz, MD, Wendy Cozen, DO,MPH, James Hicks, PhD, Peter Kuhn, PhD, Stephen Gruber, MD PhD MPH, Imran Siddiqi, MDPhD, Akil Merchant, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2751.
https://doi.org/10.1182/blood.V130.Suppl_1.2751.2751
Published: 2017
Journal Articles

Clonal Competition of Cancer Cells During Acute Lymphoblastic Leukemia Treatment

Humberto Contreras Trujillo, BS, Akil Merchant, MD, Rong Lu, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 480.
https://doi.org/10.1182/blood.V130.Suppl_1.480.480
Published: 2017
Journal Articles

Role of Remission Status and Prior Transplant in Optimizing Survival Outcomes Following Allogeneic Hematopoietic Stem Transplantation (HSCT) in Patients Who Received Inotuzumab Ozogamicin (INO) for Relapsed / Refractory (R/R) Acute Lymphoblastic Leukemia (ALL)

Partow Kebriaei, MD, Matthias Stelljes, MD, Daniel J. DeAngelo, MD, Nicola Goekbuget, MD, Hagop M. Kantarjian, MD, Anjali S. Advani, MD, Akil Merchant, MD, Wendy Stock, MD, Tao Wang, PhD, Hui Zhang, Fausto Loberiza, Erik Vandendries, MD PhD, David Marks
Journal: Blood
Blood (2017) 130 (Supplement 1): 886.
https://doi.org/10.1182/blood.V130.Suppl_1.886.886
Published: 2017
Journal Articles

Modulating Hedgehog Signaling Reduces MAPK, TGF-β, and Marrow Fibrosis in a Transgenic Mouse Model of JAK2V617F Associated Myeloproliferative Disease

Parvesh Chaudhry, PhD, Mohan Singh, PhD, Imran Siddiqi, MDPhD, Casey L. O'Connell, MD, Zhizhuang Joe Zhao, PhD, Akil Merchant, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 4216.
https://doi.org/10.1182/blood.V130.Suppl_1.4216.4216
Published: 2017
Journal Articles

The Hedgehog Regulated Transcription Factor and Tumor Suppressor, Gli3, Regulates Hematopoietic Stem Cell Number, Self-Renewal and Differentiation

Parvesh Chaudhry, PhD, Mohan Singh, PhD, Amy R McManus, Aparna Jorapur, Stephen James Capone, BS, Giridharan Ramsingh, MD, Akil Merchant, MD
Journal: Blood
Blood (2015) 126 (23): 2381.
https://doi.org/10.1182/blood.V126.23.2381.2381
Published: 2015
Journal Articles

Presence of Primary Cilia in Human Hematopoietic System

Mohan Singh, PhD, Parvesh Chaudhry, PhD, Giridharan Ramsingh, MD, Akil Merchant, MD
Journal: Blood
Blood (2015) 126 (23): 4762.
https://doi.org/10.1182/blood.V126.23.4762.4762
Published: 2015
Journal Articles

PI3Kdelta Inhibitor, CAL-101, De-Adheres Primary Pre-B ALL from VCAM-1 and Induces Apoptosis in Primary Pre-B ALL

Sajad Khazal, MD, Enzi Jiang, MD PhD, Stephanie Shishido, Osanna Kosoyan, Kim Hye-Na, Alexa Velasquez, Yao-Te Hsieh, Hisham Abdel-Azim, MD, Ann M Mohrbacher, MD, Akil Merchant, MD, Alan S. Wayne, MD, Nora Heisterkamp, PhD, Yong-Mi Kim, MD MPH, PhD
Journal: Blood
Blood (2014) 124 (21): 3715.
https://doi.org/10.1182/blood.V124.21.3715.3715
Published: 2014
Journal Articles

DNA Methylation Changes In Aging Human CD34+ Cells Coincide With Hotspots Of Disordered Methylation In AML At Imprinted and Allelically Methylated Regions

Tim Triche, Jr, Ph.D, Stephen Capone, B.S, Akil Merchant, MD, Preet Chaudhary, MD, PhD, Giridharan Ramsingh, M.D
Journal: Blood
Blood (2013) 122 (21): 1193.
https://doi.org/10.1182/blood.V122.21.1193.1193
Published: 2013
Journal Articles

A Functional Thrombopoietin Receptor Is Required for Full Expression of Phenotype in a JAK2 V617F Transgenic Mouse Model of Polycythemia Vera

Jerry L. Spivak, MD, Akil Merchant, MD, Donna M. Williams, PhD, Ophelia Rogers, Wanming Zhao, Alison R. Moliterno, MD, Zhizhuang Joe Zhao, PhD
Journal: Blood
Blood (2012) 120 (21): 427.
https://doi.org/10.1182/blood.V120.21.427.427
Published: 2012
Journal Articles

The TGF- β Family Member Growth Differentiation Factor 15 (GDF15) Regulates the Self-Renewal of Multiple Myeloma Cancer Stem Cells

Toshihiko Tanno, DVM, PhD, Akil Merchant, MD, Jasmin R. Agarwal, MD, MSc, Qiuju Wang, MA, William Matsui, MD
Journal: Blood
Blood (2011) 118 (21): 2954.
https://doi.org/10.1182/blood.V118.21.2954.2954
Published: 2011