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Journal Articles

Diffuse Large B-Cell Lymphoma Has a Low Frequency of dMMR and High Frequencies of DNA Mismatch Repair Protein High Expression Associated with Lower T-Cell Infiltration

Zijun Y. Xu-Monette, Li Yu, Cancan Luo, Yong Li, Govind Bhagat, Alexandar Tzankov, Carlo Visco, Xiangshan Fan, Xiaosheng Fang, Karen Dybkaer, Ali Sakhdari, April Chiu, Wayne Tam, Youli Zu, Eric D. Hsi, F. B. Hagemeister, Dennis O'Malley, Qingyan Au, Harry Nunns, Heounjeong Go, Maurilio Ponzoni, Andrés José María Ferreri, Michael Møller, Benjamin M. Parsons, Joannes H.J.M. Van Krieken, Miguel Piris, Jane Winter, Bing Xu, Mingzhi Zhang, Ken H. Young
Journal: Blood
Blood (2023) 142 (Supplement 1): 6079.
https://doi.org/10.1182/blood-2023-178366
Published: 2023
Journal Articles

Tumor-Infiltrating Normal B Lymphocytes Have Remarkable Prognostic Effects and Are Crucial for Antitumor Immune Responses in Diffuse Large B-Cell Lymphoma

Zijun Y. Xu-Monette, Yong Li, Thomas Snyder, Tiantian Yu, Tingxun LU, Alexandar Tzankov, Carlo Visco, Govind Bhagat, Wenbin Qian, Karen Dybkaer, April Chiu, Wayne Tam, Youli Zu, Eric D. Hsi, Frederick Hagemeister, Heounjeong Go, Maurilio Ponzoni, Andrés José María Ferreri, Michael Møller, Benjamin M. Parsons, Joannes H.J.M. Van Krieken, Yingjun Wang, Miguel Angel Piris, Jane Winter, Qingyan Au, Ilan Kirsch, Mingzhi Zhang, John D Shaughnessy, Jr, Bing Xu, Ken H. Young
Journal: Blood
Blood (2023) 142 (Supplement 1): 429.
https://doi.org/10.1182/blood-2023-179972
Published: 2023
Journal Articles

Disease-Modifying Potential of BET Inhibitor Pelabresib (CPI-0610) As Demonstrated By Improvements in Bone Marrow Function and Clinical Activity in Patients with Myelofibrosis - Preliminary Data

Srdan Verstovsek, Mohamed E Salama, John Mascarenhas, Moshe Talpaz, Ruben A. Mesa, Alessandro Vannucchi, Raajit Rampal, Stephen T. Oh, Horatiu Olteanu, April Chiu, Dong Chen, Curtis A. Hanson, Natalia Curto-Garcia, Pietro Taverna, Jike Cui, Oksana Zavidij, Zehua Chen, Gozde Colak, Sergey Efuni, Patricia J Keller, Patrick Trojer, Claire N. Harrison
Journal: Blood
Blood (2021) 138 (Supplement 1): 2568.
https://doi.org/10.1182/blood-2021-152267
Published: 2021
Journal Articles

Determining Clinical Course of Diffuse Large B-Cell Lymphoma Using Targeted Transcriptome and Machine Learning Algorithms

Maher Albitar, Hong Zhang, Andre H. Goy, Zijun Xu-Monette, Govind Bhagat, Carlo Visco, Alexandar Tzankov, Xiaosheng Fang, Feng Zhu, Karen Dybkaer, April Chiu, Wayne Tam, Youli Zu, Eric D. Hsi, F. B. Hagemeister, Jooryung Huh, Maurilio Ponzoni, Andrés J M Ferreri, Michael Moller, Benjamin M Parsons, Joannes H.J.M. Van Krieken, Miguel Angel Piris, Jane N. Winter, Yong Li, Bing Xu, Ken H. Young
Journal: Blood
Blood (2021) 138 (Supplement 1): 2395.
https://doi.org/10.1182/blood-2021-148841
Published: 2021
Journal Articles

Indoleamine 2,3-Dioxygenase-1 Expressing Dendritic Cell Populations Are Associated with Tumor-Induced Immune Tolerance & Aggressive Disease Biology in Chronic Myelomonocytic Leukemia

Abhishek A. Mangaonkar, MD, Kaaren K. Reichard, MD, April Chiu, MD, Matthew T Howard, MD, Rebecca L King, MD, Ryan M. Carr, MD, PhD, Bonnie M Alver, Keith D. Robertson, Margot Cousin, PhD, Jose C Villasboas, Martin E. Fernandez-Zapico, MD, Terra L. Lasho, PhD, Naseema Gangat, MBBS, Aref Al-Kali, MD, Michelle A. Elliott, MD, William J. Hogan, MBBCh, Mark R. Litzow, MD, Animesh Pardanani, MBBS, PhD, Eric Solary, MD PhD, Ayalew Tefferi, MD, Mrinal M. Patnaik, MD MBBS
Journal: Blood
Blood (2018) 132 (Supplement 1): 4344.
https://doi.org/10.1182/blood-2018-99-113881
Published: 2018
Journal Articles

Clinical Significance of PD-1 and PD-L1 Expression and Ongoing Interaction in the Tumor Microenvironment in Diffuse Large B Cell Lymphoma (DLBCL) Treated with R-CHOP

Zijun Yidan Xu-Monette, PhD, Li Yu, MD, Thai Tran, Lisa Adams, Nathan Roscoe, Ganiraju Manyam, Carlo Visco, Alexandar Tzankov, Karen Dybkær, PhD, Govind Bhagat, MD, April Chiu, MD, Wayne Tam, MD PhD, Youli Zu, MD PhD, Eric D. Hsi, MD, Joannes H.J.M. Van Krieken, PhDMD, Jooryung Huh, MD PhD, Maurilio Ponzoni, MD, Andres Ferreri, MD, Michael Boe Møller, Miguel Angel Piris, PhDMD, Jane N. Winter, MD, L. Jeffrey Medeiros, MD, George Rassidakis, MD PhD, Christine Angela Vaupel, PhD, Yong Li, PhD, Naveen Dakappagari, Ken H. Young, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 197.
https://doi.org/10.1182/blood.V130.Suppl_1.197.197
Published: 2017
Journal Articles

Assessment of CD37 B-cell antigen and cell of origin significantly improves risk prediction in diffuse large B-cell lymphoma

Clinical Trials & Observations
Zijun Y. Xu-Monette, Ling Li, John C. Byrd, Kausar J. Jabbar, Ganiraju C. Manyam, Charlotte Maria de Winde, Michiel van den Brand, Alexandar Tzankov, Carlo Visco, Jing Wang, Karen Dybkaer, April Chiu, Attilio Orazi, Youli Zu, Govind Bhagat, Kristy L. Richards, Eric D. Hsi, William W. L. Choi, Jooryung Huh, Maurilio Ponzoni, Andrés J. M. Ferreri, Michael B. Møller, Ben M. Parsons, Jane N. Winter, Michael Wang, Frederick B. Hagemeister, Miguel A. Piris, J. Han van Krieken, L. Jeffrey Medeiros, Yong Li, Annemiek B. van Spriel, Ken H. Young
Journal: Blood
Blood (2016) 128 (26): 3083–3100.
https://doi.org/10.1182/blood-2016-05-715094
Published: 2016
Includes: Supplemental data
Journal Articles

Brentuximab vedotin and AVD followed by involved-site radiotherapy in early stage, unfavorable risk Hodgkin lymphoma

Clinical Trials & Observations
Anita Kumar, Carla Casulo, Joachim Yahalom, Heiko Schöder, Paul M. Barr, Philip Caron, April Chiu, Louis S. Constine, Pamela Drullinsky, Jonathan W. Friedberg, John F. Gerecitano, Audrey Hamilton, Paul A. Hamlin, Steven M. Horwitz, Alexandra G. Jacob, Matthew J. Matasar, Gianna N. McArthur, Susan J. McCall, Alison J. Moskowitz, Ariela Noy, Maria L. Palomba, Carol S. Portlock, David J. Straus, Nicholas VanderEls, Stephanie L. Verwys, Joanna Yang, Anas Younes, Andrew D. Zelenetz, Zhigang Zhang, Craig H. Moskowitz
Journal: Blood
Blood (2016) 128 (11): 1458–1464.
https://doi.org/10.1182/blood-2016-03-703470
Published: 2016
Includes: Supplemental data
Journal Articles

Dose-Dependent Role of the Cohesin Complex in Normal and Malignant Hematopoiesis

Aaron D. Viny, MD MS, Christopher J. Ott, PhD, Barbara Spitzer, MD, Martin A Rivas, PhD, Cem Meydan, Efthymia Papalexi, Dana Yelin, MD, Kaitlyn Shank, BS, Jaime Reyes, April Chiu, MD, Swapna Thota, MD, Jaroslaw P Maciejewski, MD PhD FACP, Ari Melnick, MD, James E. Bradner, MD, Ross L. Levine, MD
Journal: Blood
Blood (2015) 126 (23): 435.
https://doi.org/10.1182/blood.V126.23.435.435
Published: 2015
Journal Articles

Akt Activation Confers an Inferior Survival in Patients with Activated B-Cell Subtype of Diffuse Large B-Cell Lymphoma: A Report from the International DLBCL Rituximab-CHOP Consortium Program

Qi Shen, Zijun Yidan Xu-Monette, PhD, Ganiraju Manyam, Carlo Visco, Alexander Tzankov, MD PhD, Xin Cao, Lijuan Deng, Santiago Montes-Moreno, MD PhD, Karen Dybkær, April Chiu, MD, Attilio Orazi, MD, Youli Zu, MD PhD, Govind Bhagat, MD, Kristy L. Richards, MDPhD, Eric D. Hsi, MD, William Choi, Joannes H.J.M. Van Krieken, PhDMD, Jooryung Huh, Maurilio Ponzoni, MD, Andres J.M. Ferreri, MD PhD, John P. Farnen, MD, Michael B. Møller, MD DMSc, Jane N. Winter, MD, Miguel Angel A. Piris, MD PhD, L. Jeffrey Medeiros, MD, Ken H. Young, MD PhD
Journal: Blood
Blood (2014) 124 (21): 143.
https://doi.org/10.1182/blood.V124.21.143.143
Published: 2014
Journal Articles

NF-κB Subunit c-Rel Cooperates with Myc and Mutated p53 to Confer Significantly Worse Survival in Patients with Diffuse Large B-Cell Lymphoma: A Report from the International DLBCL Rituximab-CHOP Consortium Program

Ling Li, MD, Zijun Yidan Xu-Monette, PhD, Chi Young Ok, MD, Alexander Tzanko, Carlo Visco, Nora Gisin, Santiago Montes-Moreno, MD PhD, Karen Dybkær, April Chiu, MD, Attilio Orazi, MD, Youli Zu, MD PhD, Govind Bhagat, MD, Kristy L. Richards, MDPhD, Eric D. Hsi, MD, William W. L. Choi, MD PhD, Joannes H.J.M. Van Krieken, PhDMD, Jooryung Huh, Maurilio Ponzoni, Andres J.M. Ferreri, MD PhD, Michael B. Møller, MD DMSc, Ronald S. Go, MD, Jane N. Winter, MD, Miguel A. Piris, MD PhD, L. Jeffrey Medeiros, MD, Ken H. Young, MD PhD
Journal: Blood
Blood (2014) 124 (21): 1620.
https://doi.org/10.1182/blood.V124.21.1620.1620
Published: 2014
Journal Articles

STAT3 Expression and Clinical Implications In De Novo Diffuse Large B-Cell Lymphoma: A Report From The International DLBCL Rituximab-CHOP Consortium Program

Chi Young Ok, MD, Zijun Y. Xu-Monette, PhD, Alexander Tzankov, MD, PhD, Carlo Visco, MD, Santiago M. Montes, MD, PhD, Karen Dybkaer, PhD, April Chiu, MD, Attilio Orazi, MD, Youli Zu, MD, PhD, Govind Bhagat, MD, PhD, Kristy L. Richards, MD PhD, Eric D. Hsi, MD, William W. L. Choi, MD, PhD, Joannes H.J.M. Van Krieken, PhD, MD, Qin Huang, MD, PhD, Jooryung Huh, MD, Weiyun Z. Ai, MD, PhD, Maurilio Ponzoni, MD, AndrÉs J.M. Ferreri,, MD, PhD, John P. Farnen, MD, FACP, Michael B. Moller, MD, PhD, Jane N. Winter, MD, Miguel A. Piris, MD, PhD, L. Jeffrey Medeiros, MD, Ken H. Young, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 365.
https://doi.org/10.1182/blood.V122.21.365.365
Published: 2013
Journal Articles

MYC Mutation Profiling In 708 De Novo Diffuse Large B-Cell Lymphoma Demonstrates That Genetic Abnormalities In The Coding Sequence and Untranslated Regions Have Different Prognostic and Clinical Significance: A Report From The International DLBCL Rituximab-CHOP Consortium Program

Zijun Y. Xu-Monette, PhD, Alexander Tzankov, MD, Yong Li, PhD, Carlo Visco, MD, Santiago Montes-Moreno, MD, PhD, Karen Dybkaer, PhD, April Chiu, MD, Attilio Orazi, MD, Youli Zu, MD, PhD, Govind Bhagat, MD, Kristy L. Richards, MD PhD, Eric D. Hsi, MD, William W. L. Choi, MD, PhD, Joannes H.J.M. Van Krieken, PhD, MD, Jooryung Huh, MD, Weiyun Z. Ai, MD, PhD, Maurilio Ponzoni, MD, Andres J.M. Ferreri, MD, PhD, John P. Farnen, MD, FACP, Michael B. Moller, MD, PhD, Jane N. Winter, MD, Miguel A. Piris, MD, PhD, L. Jeffrey Medeiros, MD, Ken H. Young, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 363.
https://doi.org/10.1182/blood.V122.21.363.363
Published: 2013
Journal Articles

Radiation Therapy Significantly Improves Survival Of Patients With Diffuse Large B-Cell Lymphoma Associated With MYC Translocation: A Report From The International DLBCL Rituximab-CHOP Consortium Program

Zijun Y. Xu-Monette, PhD, Bouthaina S. Dabaja, MD, Alexander Tzankov, MD, PhD, Carlo Visco, MD, Roberto N. Miranda, MD, Karen Dybkaer, PhD, April Chiu, MD, Attilio Orazi, MD, Youli Zu, MD, PhD, Govind Bhagat, MD, Kristy L. Richards, MD PhD, Eric D. Hsi, MD, Wai Lap Choi, MD, Joannes H.J.M. Van Krieken, PhD, MD, Jooryung Huh, MD, Weiyun Z. Ai, MD, PhD, Maurilio Ponzoni, MD, Andres Ferreri, MD, PhD, Michael B. Moller, MD, PhD, Xiaoying Zhao, MD, Ronald S. Go, MD, Jane N. Winter, MD, Miguel Angel A. Piris, MD, PhD, Timothy J. McDonnell, MD, PhD, Yong Li, PhD, L. Jeffrey Medeiros, MD, Ken H. Young, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 641.
https://doi.org/10.1182/blood.V122.21.641.641
Published: 2013
Journal Articles

Radiation Therapy Significantly Improves Survival Of Patients With Diffuse Large B-Cell Lymphoma Associated With MYC Translocation: A Report From The International DLBCL Rituximab-CHOP Consortium Program

Zijun Y. Xu-Monette, PhD, Bouthaina S. Dabaja, MD, Alexander Tzankov, MD, PhD, Carlo Visco, MD, Roberto N. Miranda, MD, Karen Dybkaer, PhD, April Chiu, MD, Attilio Orazi, MD, Youli Zu, MD, PhD, Govind Bhagat, MD, Kristy L. Richards, MD PhD, Eric D. Hsi, MD, Wai Lap Choi, MD, Joannes H.J.M. Van Krieken, PhD, MD, Jooryung Huh, MD, Weiyun Z. Ai, MD, PhD, Maurilio Ponzoni, MD, Andres Ferreri, MD, PhD, Michael B. Moller, MD, PhD, Xiaoying Zhao, MD, Ronald S. Go, MD, Jane N. Winter, MD, Miguel Angel A. Piris, MD, PhD, Timothy J. McDonnell, MD, PhD, Yong Li, PhD, L. Jeffrey Medeiros, MD, Ken H. Young, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 213.
https://doi.org/10.1182/blood.V122.21.213.213
Published: 2013
Journal Articles

MDM2 phenotypic and genotypic profiling, respective to TP53 genetic status, in diffuse large B-cell lymphoma patients treated with rituximab-CHOP immunochemotherapy: a report from the International DLBCL Rituximab-CHOP Consortium Program

Zijun Y. Xu-Monette, Michael B. Møller, Alexander Tzankov, Santiago Montes-Moreno, Wenwei Hu, Ganiraju C. Manyam, Louise Kristensen, Lei Fan, Carlo Visco, Karen Dybkær, April Chiu, Wayne Tam, Youli Zu, Govind Bhagat, Kristy L. Richards, Eric D. Hsi, William W. L. Choi, J. Han van Krieken, Qin Huang, Jooryung Huh, Weiyun Ai, Maurilio Ponzoni, Andrés J. M. Ferreri, Lin Wu, Xiaoying Zhao, Carlos E. Bueso-Ramos, Sa A. Wang, Ronald S. Go, Yong Li, Jane N. Winter, Miguel A. Piris, L. Jeffrey Medeiros, Ken H. Young
Journal: Blood
Blood (2013) 122 (15): 2630–2640.
https://doi.org/10.1182/blood-2012-12-473702
Published: 2013
Includes: Supplemental data
Journal Articles

Detection of an NRAS mutation in Erdheim-Chester disease

Eli L. Diamond, Omar Abdel-Wahab, Elena Pentsova, Laetitia Borsu, April Chiu, Julie Teruya-Feldstein, David M. Hyman, Marc Rosenblum
Journal: Blood
Blood (2013) 122 (6): 1089–1091.
https://doi.org/10.1182/blood-2013-02-482984
Published: 2013
Journal Articles

MYC/BCL2 protein coexpression contributes to the inferior survival of activated B-cell subtype of diffuse large B-cell lymphoma and demonstrates high-risk gene expression signatures: a report from The International DLBCL Rituximab-CHOP Consortium Program

CME
Shimin Hu, Zijun Y. Xu-Monette, Alexander Tzankov, Tina Green, Lin Wu, Aarthi Balasubramanyam, Wei-min Liu, Carlo Visco, Yong Li, Roberto N. Miranda, Santiago Montes-Moreno, Karen Dybkaer, April Chiu, Attilio Orazi, Youli Zu, Govind Bhagat, Kristy L. Richards, Eric D. Hsi, William W. L. Choi, Xiaoying Zhao, J. Han van Krieken, Qin Huang, Jooryung Huh, Weiyun Ai, Maurilio Ponzoni, Andrés J. M. Ferreri, Fan Zhou, Graham W. Slack, Randy D. Gascoyne, Meifeng Tu, Daina Variakojis, Weina Chen, Ronald S. Go, Miguel A. Piris, Michael B. Møller, L. Jeffrey Medeiros, Ken H. Young
Journal: Blood
Blood (2013) 121 (20): 4021–4031.
https://doi.org/10.1182/blood-2012-10-460063
Published: 2013
Includes: Supplemental data
Journal Articles

CD30 expression defines a novel subgroup of diffuse large B-cell lymphoma with favorable prognosis and distinct gene expression signature: a report from the International DLBCL Rituximab-CHOP Consortium Program Study

Shimin Hu, Zijun Y. Xu-Monette, Aarthi Balasubramanyam, Ganiraju C. Manyam, Carlo Visco, Alexander Tzankov, Wei-min Liu, Roberto N. Miranda, Li Zhang, Santiago Montes-Moreno, Karen Dybkær, April Chiu, Attilio Orazi, Youli Zu, Govind Bhagat, Kristy L. Richards, Eric D. Hsi, William W. L. Choi, J. Han van Krieken, Qin Huang, Jooryung Huh, Weiyun Ai, Maurilio Ponzoni, Andrés J. M. Ferreri, Xiaoying Zhao, Jane N. Winter, Mingzhi Zhang, Ling Li, Michael B. Møller, Miguel A. Piris, Yong Li, Ronald S. Go, Lin Wu, L. Jeffrey Medeiros, Ken H. Young
Journal: Blood
Blood (2013) 121 (14): 2715–2724.
https://doi.org/10.1182/blood-2012-10-461848
Published: 2013
Includes: Supplemental data
Journal Articles

Prognostic Significance and Phenotypic Manifestations of MYC/BCL2 Protein Expression in Diffuse Large B-Cell Lymphoma (DLBCL) with Extranodal Organ Involvement: A Report of the International DLBCL Rituximab-CHOP Consortium Program Study

Anusha Madadi, MD, Meghana Raghavendra, MD, Shimin Hu, Zijun Y. Xu-Monette, PhD, Carlo Visco, MD, Alexander Tzankov, MD, Santiago Montes-Moreno, MD, Karen Dybkaer, April Chiu, MD, Attilio Orazi, MD, Youli Zu, MD, PhD, Govind Bhagat, MD, Cherie H. Dunphy, MD, Eric D. Hsi, MD, Frank X. Zhao, MD, PhD, William W. L. Choi, MD, Xiaoying Zhao, MD, Joannes H.J.M. Van Krieken, PhD, MD, Jooryung Huh, MD, Qin Huang, MD, PhD, Wei Ai, MD, Maurilio Ponzoni, Andrés J.M. Ferreri, MD, Fan Zhou, MD, PhD, Jane N. Winter, MD, Miguel Piris, MD, Michael B. Møller, MD, DMSc, L. Jeffrey Medeiros, MD, Ronald S. Go, MD, Ken H. Young, MD
Journal: Blood
Blood (2012) 120 (21): 544.
https://doi.org/10.1182/blood.V120.21.544.544
Published: 2012