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Journal Articles

Near early T-precursor lymphoblastic leukemia with marked flower petal nuclei: blast with unique cyanthiform nucleus

Qian Wu, Dong Chen
Journal: Blood
Blood (2024) 144 (17): 1846.
https://doi.org/10.1182/blood.2024026443
Published: 2024
Journal Articles

Targeted Protein Degradation for c-MYC Overcomes Therapy Resistance in T-Cell Acute Lymphoblastic Leukemias

Faryal Munir, Shayaun Khazaei, Phoebe H. Calkins, Darah Scruggs, Hideaki Mizuno, Lauren B. Ostermann, Branko Cuglievan, Miriam B. Garcia, Dong Chen, Youzhi Tong, Zhihua Ren, Michael Andreeff, Yuki Nishida
Journal: Blood
Blood (2023) 142 (Supplement 1): 1447.
https://doi.org/10.1182/blood-2023-187496
Published: 2023
Journal Articles

ELISA-Negative Platelet-Activating Anti-PF4 Antibodies Can Cause HIT and Monoclonal Gammopathy of Thrombotic Significance (MGTS)

Adam Kanack, Nelson Leung, Noah Splinter, Emily Mauch, Morayma Reyes Gil, Leben Tefera, Sakshi Jasra, Andrew Goodwin, Hadiyah Audil, Aneel Ashrani, Nathaniel L. Robinson, Ana I. Casanegra, Curtis Jones, Shannon Pechauer, Erin Yttre, Mindy Kohlhagen, Rachel Leger, David L Murray, Dong Chen, Rajiv K. Pruthi, Anand Pabmanabhan
Journal: Blood
Blood (2023) 142 (Supplement 1): 682.
https://doi.org/10.1182/blood-2023-181121
Published: 2023
Journal Articles

Genetic Study of Patients with Severe Dense Granule Deficiency: Unraveling the Underlying Genetic Complexity of Hermansky-Pudlak Syndrome

Rajiv K. Pruthi, Julie Majerus, Dong Chen
Journal: Blood
Blood (2023) 142 (Supplement 1): 1221.
https://doi.org/10.1182/blood-2023-179976
Published: 2023
Journal Articles

Comparison of World Health Organization and International Consensus Classification Guidelines for Myeloid Neoplasms Harboring TP53 -Mutations Using an Independent International Cohort

Mithun V Shah, Monika Kutyna, Syed Shah, Elizabeth Ngoc Hoa Tran, Anmol Baranwal, Dariusz Ladon, Aref Al-Kali, Anna Brown, Dong Chen, Patricia Greipp, Kebede Begna, Mark R. Litzow, William J. Hogan, Peter Bardy, Sharad Kumar, David T Yeung, Mrinal M. Patnaik, James M. Foran, Rong He, Naseema Gangat, Hamish S Scott, Cecilia Y. Arana Yi, Hassan Alkhateeb, Abhishek A Mangaonkar, Daniel Thomas, Christopher Norman Hahn, Attilio Orazi, Daniel A. Arber, Chung Hoow Kok, Ayalew Tefferi, Devendra Hiwase
Journal: Blood
Blood (2023) 142 (Supplement 1): 3243.
https://doi.org/10.1182/blood-2023-187860
Published: 2023
Journal Articles

Single-Hit TP53 mut Is Associated with Poor Outcomes in Therapy-Related but Not De Novo Myelodysplastic Syndromes: Importance of Clinical History

Devendra Hiwase, Anmol Baranwal, Syed Shah, Monika Kutyna, Christopher Norman Hahn, Maymona Abdelmajid, Danielle Rud, Rakchha Chhetri, Kaaren K. Reichard, Dong Chen, Thomas Wiseman, Anna Brown, Hamish S Scott, David T Yeung, David M. Ross, Daniel Thomas, Aref Al-Kali, Hassan Alkhateeb, James M. Foran, Cecilia Y. Arana Yi, Naseema Gangat, Mrinal M. Patnaik, Ayalew Tefferi, Chung Hoow Kok, Rong He, Mithun V Shah
Journal: Blood
Blood (2023) 142 (Supplement 1): 4608.
https://doi.org/10.1182/blood-2023-187905
Published: 2023
Journal Articles

Stem-Cell Enriched Cellular Hierarchy of TP53 Mutant Acute Myeloid Leukemia Is Vulnerable to Targeted Protein Degradation of c-MYC

Yuki Nishida, Edward Ayoub, Darah Scruggs, Shayaun Khazaei, Faryal Munir, Lauren B. Ostermann, Po Yee Mak, Ke Baozhen, Bing Z. Carter, Natalia Baran, Abhishek Maiti, Vakul Mohanty, Ken Chen, Nicholas Navin, Torsten Haferlach, Zhihua Ren, Youzhi Tong, Dong Chen, Ghayas C. Issa, Michael Andreeff
Journal: Blood
Blood (2023) 142 (Supplement 1): 583.
https://doi.org/10.1182/blood-2023-174938
Published: 2023
Journal Articles

Aberrant Activity of the Calcium Sensor STIM1 Underlies Congenital Platelet Disorders and Myeloproliferative Neoplasms

Molly Brakhane, Vittorio Abbonante, Angelo B. A. Laranjeira, Christian Di Buduo, Brooke Sadler, Katrina Ashworth, Tim Kong, Fan He, Mary C. Fulbright, Dong Chen, Regina Clemens, Elena Pegoraro, Michele P. Lambert, Kandace Gollomp, Jorge Di Paola, Alessandra Balduini, Stephen T. Oh
Journal: Blood
Blood (2023) 142 (Supplement 1): 995.
https://doi.org/10.1182/blood-2023-186413
Published: 2023
Journal Articles

G Protein-Coupled Receptor 183 Plays a Prognostic Factor in Acute Myeloid Leukemia By Regulating Immune Regulation

Fenglin Li, Dong Chen, Chen Li, Haihui Zhuang, Peipei Ye, Jie Jin, Ying Lu
Journal: Blood
Blood (2023) 142 (Supplement 1): 6043.
https://doi.org/10.1182/blood-2023-185692
Published: 2023
Journal Articles

Cytarabine Plus Etoposideis+Peg-Rhg-CSF Is More Effective Than Cyclophosphamide + G-CSF As a Stem Cell Mobilization Regimen in Poorly Mobilized MM and Lymphoma

Yixuan Cheng, Dong Chen, Renzhi Pei, Xiaohong Du, Chen Li, Xianxu Zhuang, Fenglin Li, Peipei Ye, Ying Lu
Journal: Blood
Blood (2023) 142 (Supplement 1): 7103.
https://doi.org/10.1182/blood-2023-185595
Published: 2023
Journal Articles

Off-the-shelf cryopreserved platelets for the detection of HIT and VITT antibodies

Adam J. Kanack, Curtis G. Jones, Bandana Singh, Rachel R. Leger, Noah P. Splinter, Nahla M. Heikal, Rajiv K. Pruthi, Dong Chen, Gemlyn George, Mouhamed Y. Abou-Ismail, Geoffrey D. Wool, Krishna Gundabolu, Anand Padmanabhan
Journal: Blood
Blood (2022) 140 (25): 2722–2729.
https://doi.org/10.1182/blood.2022017283
Published: 2022
Includes: Supplemental data
Journal Articles

"Autoimmune HIT", a Potential Diagnostic Artifact Due to Remnant Heparin in HIT Samples, Is Not Associated with More Severe Outcomes

Adam Kanack, Rachel Leger, Abdulrahman Saadalla, Nahla Heikal, Dong Chen, David Garcia, Rajiv K. Pruthi, Anand Padmanabhan
Journal: Blood
Blood (2022) 140 (Supplement 1): 1963–1964.
https://doi.org/10.1182/blood-2022-169711
Published: 2022
Journal Articles

The Lupus Anticoagulant Titer Is Associated with Elevated Anti-Phosphatidyl-Serine/Prothrombin Antibody Levels

Abdulrahman Saadalla, Dong Chen, Rajiv K. Pruthi, Nahla Heikal, Melissa Snyder, Aneel A. Ashrani, Jansen Seheult
Journal: Blood
Blood (2022) 140 (Supplement 1): 2669–2670.
https://doi.org/10.1182/blood-2022-170992
Published: 2022
Journal Articles

Combination of Menin and IDH Mutant Inhibition in Acute Myeloid Leukemia

James J. Yoon, Hongzhi Miao, Trupta Purohit, Dong Chen, Tomasz Cierpicki, Jolanta Grembecka
Journal: Blood
Blood (2022) 140 (Supplement 1): 5946.
https://doi.org/10.1182/blood-2022-168834
Published: 2022
Journal Articles

Venetoclax in Combination with Homoharringtonine and Cytarabine in the Treatment of Relapsed/Refractory Early T-Cell Precursor Acute Lymphoblastic Leukaemia: A Single Arm, Multicenter, Prospective, Phase II, Pilot Trial

Wenjuan Yu, Hongsheng Zhou, Lijing Shen, Dong Chen, Xiang Zhang, Yanan Zhu, Xin Huang, Ying Lu, Jian Hou, Qifa Liu, Jie Jin
Journal: Blood
Blood (2022) 140 (Supplement 1): 3260–3261.
https://doi.org/10.1182/blood-2022-164933
Published: 2022
Journal Articles

Clinical Benefit Associated with Biomarker Changes Indicative of Disease Modification in Patients with Myelofibrosis Treated with the BET Inhibitor Pelabresib As Monotherapy or in Combination with Ruxolitinib

Joseph Scandura, Srdan Verstovsek, Marina Kremyanskaya, Moshe Talpaz, Raajit K Rampal, Alessandro Vannucchi, Vikas Gupta, Francesca Palandri, Andrea Patriarca, Prithviraj Bose, Dong Chen, Oksana Zavidij, Jike Cui, Tzuu-Wang Chang, Pietro Taverna, John Mascarenhas, Claire Harrison
Journal: Blood
Blood (2022) 140 (Supplement 1): 1523–1525.
https://doi.org/10.1182/blood-2022-159409
Published: 2022
Journal Articles

Reappraisal of Mast Cell Leukemia Based on a Single Institution Review of 16 Cases: Role of Mast Cell Morphology in Determining Clinical Outcome

Animesh Pardanani, Ayalew Tefferi, Amritpal Singh, Aref Al-Kali, Mrinal M. Patnaik, William J. Hogan, Kebede Begna, Michelle A Elliott, Nandita Khera, Jeanne M. Palmer, Naseema Gangat, Attilio Orazi, Katalin Kelemen, Kaaren K. Reichard, Dong Chen
Journal: Blood
Blood (2022) 140 (Supplement 1): 6872–6873.
https://doi.org/10.1182/blood-2022-167720
Published: 2022
Journal Articles

Disease-Modifying Potential of BET Inhibitor Pelabresib (CPI-0610) As Demonstrated By Improvements in Bone Marrow Function and Clinical Activity in Patients with Myelofibrosis - Preliminary Data

Srdan Verstovsek, Mohamed E Salama, John Mascarenhas, Moshe Talpaz, Ruben A. Mesa, Alessandro Vannucchi, Raajit Rampal, Stephen T. Oh, Horatiu Olteanu, April Chiu, Dong Chen, Curtis A. Hanson, Natalia Curto-Garcia, Pietro Taverna, Jike Cui, Oksana Zavidij, Zehua Chen, Gozde Colak, Sergey Efuni, Patricia J Keller, Patrick Trojer, Claire N. Harrison
Journal: Blood
Blood (2021) 138 (Supplement 1): 2568.
https://doi.org/10.1182/blood-2021-152267
Published: 2021
Journal Articles

Anthracycline Choices for Induction Chemotherapy Among 797 Consecutive Adult Patients with Acute Myeloid Leukemia: Daunorubicin-60 Vs Idarubicin-12 Vs Daunorubicin-90

Kebede H. Begna, Naseema Gangat, Mithun V. Shah, Hassan B. Alkhateeb, Mrinal M. Patnaik, Aref Al-Kali, Michelle A. Elliot, William J Hogan, Mark R. Litzow, C. Christopher Hook, Abhishek A. Mangaonkar, David S Viswanatha, Dong Chen, Animesh D. Pardanani, Rhett P. Ketterling, Ayalew Tefferi
Journal: Blood
Blood (2021) 138 (Supplement 1): 1267.
https://doi.org/10.1182/blood-2021-147485
Published: 2021
Journal Articles

Diagnostic Utility of High Dose Heparin Confirmation Step in Heparin Induced Thrombocytopenia ELISA Assay

Abdulrahman Saadalla, Rachel Leger, Aneel A. Ashrani, Rajiv K. Pruthi, Dong Chen, Anand Padmanabhan, Nahla Heikal
Journal: Blood
Blood (2021) 138 (Supplement 1): 3228.
https://doi.org/10.1182/blood-2021-154504
Published: 2021