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Journal Articles

Aberrant Activity of the Calcium Sensor STIM1 Underlies Congenital Platelet Disorders and Myeloproliferative Neoplasms

Molly Brakhane, Vittorio Abbonante, Angelo B. A. Laranjeira, Christian Di Buduo, Brooke Sadler, Katrina Ashworth, Tim Kong, Fan He, Mary C. Fulbright, Dong Chen, Regina Clemens, Elena Pegoraro, Michele P. Lambert, Kandace Gollomp, Jorge Di Paola, Alessandra Balduini, Stephen T. Oh

Blood (2023) 142 (Supplement 1): 995.

https://doi.org/10.1182/blood-2023-186413

Published: 2023

Journal Articles

Newly Identified Roles for PIEZO1 Mechanosensor in Controlling Normal Megakaryocyte Development and in Primary Myelofibrosis

Iris Karkempetzaki, Vittorio Abbonante, Catherine Leon, Nasi Huang, Christian Di Buduo, Daniele Cattaneo, Christina Ward, Shinobu Matsuura, Alessandra Iurlo, Alessandra Balduini, Katya Ravid

Blood (2023) 142 (Supplement 1): 6355.

https://doi.org/10.1182/blood-2023-180117

Published: 2023

Journal Articles

Proteomic Screening Identifies Megakaryocyte Derived PF4/Cxcl4 As a Critical Driver of Myelofibrosis

Alessandro Malara, Daniele Capitanio, Francesca Rossella Calledda, Vittorio Abbonante, Daniele Cattaneo, Alessandra Iurlo, Cecilia Gelfi, Alessandra Balduini

Blood (2023) 142 (Supplement 1): 1793.

https://doi.org/10.1182/blood-2023-188967

Published: 2023

Journal Articles

Novel variants in GALE cause syndromic macrothrombocytopenia by disrupting glycosylation and thrombopoiesis

Ana Marín-Quílez, Christian Andrea Di Buduo, Lorena Díaz-Ajenjo, Vittorio Abbonante, Elena Vuelta, Paolo Maria Soprano, Cristina Miguel-García, Sandra Santos-Mínguez, Inmaculada Serramito-Gómez, Pedro Ruiz-Sala, María Jesús Peñarrubia, Emilia Pardal, Jesús María Hernández-Rivas, José Ramón González-Porras, Ignacio García-Tuñón, Rocío Benito, José Rivera, Alessandra Balduini, José María Bastida

Blood (2023) 141 (4): 406–421.

https://doi.org/10.1182/blood.2022016995

Published: 2023

Includes: Supplemental data

Journal Articles

Increased B4GALT1 expression is associated with platelet surface galactosylation and thrombopoietin plasma levels in MPNs

Christian A. Di Buduo, Silvia Giannini, Vittorio Abbonante, Vittorio Rosti, Karin M. Hoffmeister, Alessandra Balduini

Blood (2021) 137 (15): 2085–2089.

https://doi.org/10.1182/blood.2020007265

Published: 2021

Includes: Supplemental data

Journal Articles

Defective interaction of mutant calreticulin and SOCE in megakaryocytes from patients with myeloproliferative neoplasms

Christian A. Di Buduo, Vittorio Abbonante, Caroline Marty, Francesco Moccia, Elisa Rumi, Daniela Pietra, Paolo M. Soprano, Dmitry Lim, Daniele Cattaneo, Alessandra Iurlo, Umberto Gianelli, Giovanni Barosi, Vittorio Rosti, Isabelle Plo, Mario Cazzola, Alessandra Balduini

Blood (2020) 135 (2): 133–144.

https://doi.org/10.1182/blood.2019001103

Published: 2020

Includes: Supplemental data

Journal Articles

Increased STAT5/STAT3 Intracellular Signaling in Circulating CD34+ Cells of Patients with PMF Correlates with Disease Severity

Carlotta Abbà, MSc, Rita Campanelli, Paolo Catarsi, Laura Villani, Vittorio Abbonante, PhD, Christian Andrea Di Buduo, PhD, Melania Antonietta Sesta, Vittorio Rosti, MD, Giovanni Barosi, MD, Margherita Massa

Blood (2018) 132 (Supplement 1): 4337.

https://doi.org/10.1182/blood-2018-99-114684

Published: 2018

Journal Articles

EDA Fibronectin-TLR4 Axis Sustains Megakaryocyte Expansion and Inflammation during Bone Marrow Fibrosis Progression

Alessandro Malara, PhD, Cristian Gruppi, PhD, Vittorio Abbonante, PhD, Daniele Cattaneo, MD, Luigi De Marco, MD, Alessandra Iurlo, Umberto Gianelli, MD, Andrés F Muro, PhD, Anil K Chauhan, PhD, Vittorio Rosti, MD, Giovanni Barosi, MD, Alessandra Balduini, MD

Blood (2018) 132 (Supplement 1): 1781.

https://doi.org/10.1182/blood-2018-99-116454

Published: 2018

Journal Articles

Abnormal Regulation of Intracellular Calcium in Human Megakaryocytes Contributes to the Pathophysiology of Calr-Mutant Myeloproliferative Neoplasms

Christian Andrea Di Buduo, PhD, Vittorio Abbonante, PhD, Elisa Rumi, MD, Daniela Pietra, PhD, Francesco Moccia, PhD, Giovanni Barosi, MD, Vittorio Rosti, MD, Mario Cazzola, Alessandra Balduini, MD

Blood (2018) 132 (Supplement 1): 1782.

https://doi.org/10.1182/blood-2018-99-116166

Published: 2018

Journal Articles

Upregulation of lysyl oxidase and adhesion to collagen of human megakaryocytes and platelets in primary myelofibrosis

Vittorio Abbonante, Vipul Chitalia, Vittorio Rosti, Orly Leiva, Shinobu Matsuura, Alessandra Balduini, Katya Ravid

Blood (2017) 130 (6): 829–831.

https://doi.org/10.1182/blood-2017-04-777417

Published: 2017

Includes: Supplemental data

Journal Articles

A Newly Identified Platelet and Megakaryocyte Lysyl Oxidase-Adhesion to Collagen Axis in Human Primary Myelofibrosis

Alessandra Balduini, MD, Vittorio Abbonante, PhD, Shinobu Matsuura, DVM, PhD, Vittorio Rosti, Katya Ravid, PhD DSc

Blood (2016) 128 (22): 3133.

https://doi.org/10.1182/blood.V128.22.3133.3133

Published: 2016

Journal Articles

Mutation Type As a Major Determinant of Clinical Phenotype in Myeloproliferative Neoplasms Associated with Mutant Calreticulin

Daniela Pietra, PhD, Elisa Rumi, MD, Chiara Milanesi, BS, Christian A Di Buduo, PhD, Marta Bellini, MD, Ilaria Carola Casetti, MD, Chiara Cavalloni, MD, Emanuela Sant'Antonio, Vittorio Abbonante, PhD, Maria C Renna, BS, Virginia Ferretti, PhD, Emanuela Boveri, MD, Alessandra Balduini, MD, Cristiana Pascutto, PhD, Mario Cazzola, MD

Blood (2014) 124 (21): 3215.

https://doi.org/10.1182/blood.V124.21.3215.3215

Published: 2014

Journal Articles

Phenotypical, Functional and Genetic Characterization of Mesenchymal Stem Cells Derived from the Spleen of Patients with Myelofibrosis

Blood (2014) 124 (21): 3227.

https://doi.org/10.1182/blood.V124.21.3227.3227

Published: 2014

Journal Articles

JAK2 exon 14 Skipping in Patients with Primary Myelofibrosis (PMF),

Paolo Catarsi, PhD, Vittorio Rosti, MD, Vittorio Abbonante, BS, Alessandra Balduini, MD, Gaetano Bergamaschi, MD, Elisa Bonetti, Biol Sci, Valentina Poletto, Biol Sci, Laura Villani, Biol Sci, Giovanni Barosi, MD

Blood (2011) 118 (21): 3844.

https://doi.org/10.1182/blood.V118.21.3844.3844

Published: 2011

Journal Articles

DDR1 Activation Determines Megakaryocyte Migration on Type I Collagen

Vittorio Abbonante, BS, Luca Monti, BS, Alessandra Balduini, MD

Blood (2011) 118 (21): 1330.

https://doi.org/10.1182/blood.V118.21.1330.1330

Published: 2011

NARROW

Aberrant Activity of the Calcium Sensor STIM1 Underlies Congenital Platelet Disorders and Myeloproliferative Neoplasms

Newly Identified Roles for PIEZO1 Mechanosensor in Controlling Normal Megakaryocyte Development and in Primary Myelofibrosis

Proteomic Screening Identifies Megakaryocyte Derived PF4/Cxcl4 As a Critical Driver of Myelofibrosis

Novel variants in GALE cause syndromic macrothrombocytopenia by disrupting glycosylation and thrombopoiesis

Increased B4GALT1 expression is associated with platelet surface galactosylation and thrombopoietin plasma levels in MPNs

Defective interaction of mutant calreticulin and SOCE in megakaryocytes from patients with myeloproliferative neoplasms

Increased STAT5/STAT3 Intracellular Signaling in Circulating CD34+ Cells of Patients with PMF Correlates with Disease Severity

EDA Fibronectin-TLR4 Axis Sustains Megakaryocyte Expansion and Inflammation during Bone Marrow Fibrosis Progression

Abnormal Regulation of Intracellular Calcium in Human Megakaryocytes Contributes to the Pathophysiology of Calr-Mutant Myeloproliferative Neoplasms

Upregulation of lysyl oxidase and adhesion to collagen of human megakaryocytes and platelets in primary myelofibrosis

A Newly Identified Platelet and Megakaryocyte Lysyl Oxidase-Adhesion to Collagen Axis in Human Primary Myelofibrosis

Mutation Type As a Major Determinant of Clinical Phenotype in Myeloproliferative Neoplasms Associated with Mutant Calreticulin

Phenotypical, Functional and Genetic Characterization of Mesenchymal Stem Cells Derived from the Spleen of Patients with Myelofibrosis

JAK2 exon 14 Skipping in Patients with Primary Myelofibrosis (PMF),

DDR1 Activation Determines Megakaryocyte Migration on Type I Collagen

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American Society of Hematology

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