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Michele P. Lambert
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Journal Articles

Aberrant Activity of the Calcium Sensor STIM1 Underlies Congenital Platelet Disorders and Myeloproliferative Neoplasms

Molly Brakhane, Vittorio Abbonante, Angelo B. A. Laranjeira, Christian Di Buduo, Brooke Sadler, Katrina Ashworth, Tim Kong, Fan He, Mary C. Fulbright, Dong Chen, Regina Clemens, Elena Pegoraro, Michele P. Lambert, Kandace Gollomp, Jorge Di Paola, Alessandra Balduini, Stephen T. Oh
Journal: Blood
Blood (2023) 142 (Supplement 1): 995.
https://doi.org/10.1182/blood-2023-186413
Published: 2023
Journal Articles

Genetic Variants in Canonical Wnt Signaling Pathway Associated with Pediatric ITP

Taylor Olmsted Kim, Jennifer M. Geris, Amanda B. Grimes, Rachael F. Grace, Michele P. Lambert, Melissa J. Rose, Kristin A. Shimano, Omar Niss, Cindy Neunert, Taizo A. Nakano, Derek Macmath, Bogdan Dinu, Susan E. Kirk, Jenny M. Despotovic, Jonathan M. Flanagan, Michael E. Scheurer
Journal: Blood
Blood (2023) 142 (Supplement 1): 2593.
https://doi.org/10.1182/blood-2023-175013
Published: 2023
Journal Articles

Platelet Electron Microscopy Does Not Correlate with Bleeding Scores in a Pediatric Population

Hilary Whitworth, Elizabeth Andrews, Eric Thompson, Leslie Raffini, Bhavya S Doshi, Michele P. Lambert
Journal: Blood
Blood (2023) 142 (Supplement 1): 1222.
https://doi.org/10.1182/blood-2023-181252
Published: 2023
Journal Articles

A Phase 3 Study of Eltrombopag Vs. Standard First-Line Management for Newly Diagnosed Immune Thrombocytopenia in Children: Trial in Progress Update

Amanda B. Grimes, Rachael F. Grace, Melissa J. Rose, Sanjay J. Shah, Shipra Kaicker, Carolyn Bennett, Michael Briones, Taizo A. Nakano, Stephanie A. Fritch Lilla, Jeffrey D. Lebensburger, Alexis A. Thompson, Rukhmi Bhat, Rohith Jesudas, Michele P. Lambert, Shelley E. Crary, Kerry Hege, Cathy A. Lee-Miller, Suvankar Majumdar, James B. Ford, Joshua J. Bies, Vandy Black, John Fort, Manpreet Kochhar, Julia MW Wong, Bogdan Dinu, Pei-Chi Kao, Wendy B. London, Jenny M. Despotovic, Robert J. Klaassen, Ellis J. Neufeld, Cindy Neunert, Kristin A. Shimano
Journal: Blood
Blood (2023) 142 (Supplement 1): 1223.
https://doi.org/10.1182/blood-2023-172819
Published: 2023
Journal Articles

Analysis of Clinical Cytokine Panel Profiles As Diagnostic and Prognostic Biomarkers in Pediatric Hyperinflammatory Conditions

Paul Gallo, Kevin McNerney, Caelin Foley, Laura Kagami, Kristina Wagner, Whitney Petrosa, Scott Canna, Caroline Diorio, Kathleen Sullivan, Hamid Bassiri, David T. Teachey, Edward M Behrens, Michele Paessler, Michele P. Lambert
Journal: Blood
Blood (2022) 140 (Supplement 1): 8341–8342.
https://doi.org/10.1182/blood-2022-170411
Published: 2022
Journal Articles

Quantification of Neutrophil Extracellular Traps (NETs) in Pediatric Patients with COVID-19 and Multisystem Inflammatory Syndrome (MIS-C) through Plasma and Peripheral Smear Analysis

Rachelle Thompson, Megan Zoltowski, Derick Lim, Caroline Diorio, Elizabeth Margolskee, Michele Paessler, Veronica Bochenek, Edward M Behrens, David T. Teachey, Hamid Bassiri, Michele P. Lambert, Kandace Gollomp
Journal: Blood
Blood (2022) 140 (Supplement 1): 5481–5482.
https://doi.org/10.1182/blood-2022-170932
Published: 2022
Journal Articles

An update on pediatric ITP: differentiating primary ITP, IPD, and PID

Rachael F. Grace, Michele P. Lambert
Journal: Blood
Blood (2022) 140 (6): 542–555.
https://doi.org/10.1182/blood.2020006480
Published: 2022
Journal Articles

Comprehensive Secretome Profiling Elucidates Novel Disease Biology and Identifies Pre-Infusion Candidate Biomarkers to Predict the Development of Severe Cytokine Release Syndrome in Pediatric Patients Receiving CART19

Caroline Diorio, Rawan Shraim, Regina M. Myers, Chakkapong Burudpakdee, Allison Barz Leahy, Richard Aplenc, Michele P. Lambert, Hamid Bassiri, Edward M Behrens, Vanessa E. Gonzalez, Fang Chen, Bruce L Levine, Shannon L. Maude, Amanda M. DiNofia, Alix E. Seif, J. Joseph Melenhorst, Simon F Lacey, Carl H June, David Barrett, Stephan A. Grupp, David T. Teachey
Journal: Blood
Blood (2021) 138 (Supplement 1): 167.
https://doi.org/10.1182/blood-2021-149477
Published: 2021
Journal Articles

LUNA3 Phase III Multicenter, Double-Blind, Randomized, Placebo-Controlled Trial of the Oral BTK Inhibitor Rilzabrutinib in Adults and Adolescents with Persistent or Chronic Immune Thrombocytopenia

David J. Kuter, James B Bussel, Nichola Cooper, Terry Gernsheimer, Michele P. Lambert, Howard Liebman, Michael D Tarantino, Olga Bandman, Puneet Arora, Ann Neale, Regan Burns, Mengjie Yao, Waleed Ghanima
Journal: Blood
Blood (2021) 138 (Supplement 1): 1010.
https://doi.org/10.1182/blood-2021-144504
Published: 2021
Journal Articles

The Role of PF4 Antibodies in Pediatric Sars-Cov-2 Infections

Meady Chiem, Lubica Rauova, Caroline Diorio, Kevin O McNerney, Hamid Bassiri, Kathleen Sullivan, Edward M Behrens, David T. Teachey, Michele P. Lambert
Journal: Blood
Blood (2021) 138 (Supplement 1): 1004.
https://doi.org/10.1182/blood-2021-151529
Published: 2021
Journal Articles

Immature Platelet Fraction Does Not Correlate with Treatment Response in Immune Thrombocytopenia

Emily M. Harris, Michele P. Lambert, Jenny M. Despotovic, Susan E Kirk, Abinaya Arulselvan, Matthew Basara, Brenna Cannon, Sam King, David N Williams, Rachael F. Grace
Journal: Blood
Blood (2021) 138 (Supplement 1): 1024.
https://doi.org/10.1182/blood-2021-151681
Published: 2021
Journal Articles

Premedication with Hydrocortisone Increases Risk of Adverse Drug Events and Return to Medical Care Among Pediatric Patients with ITP Treated with IVIG

Megan M Gilbert, Taylor Olmsted Kim, Susan E Kirk, Hyojeong Han, Xiaofan Huang, Kristen A Staggers, Rachael F. Grace, Cindy Neunert, Michele P. Lambert, Jenny M. Despotovic, Amanda B Grimes
Journal: Blood
Blood (2021) 138 (Supplement 1): 1917.
https://doi.org/10.1182/blood-2021-153385
Published: 2021
Journal Articles

Pediatric Patients with Immune Thrombocytopenic Purpura Have a Dysbiotic Gut Microbiome at Time of Diagnosis

Joseph H Oved, Caitlin W Elgarten, Scott G Daniel, Lidiya Denu, Michael Silverman, Kyle Bittinger, Timothy S. Olson, Michele P. Lambert
Journal: Blood
Blood (2021) 138 (Supplement 1): 3169.
https://doi.org/10.1182/blood-2021-154180
Published: 2021
Journal Articles

Transcription Factor RUNX1 Regulates Factor FXIIIA Subunit ( F13A1 ) Expression in Megakaryocytic Cells and Platelet F13A1 Expression is Downregulated in RUNX1 Haplodeficiency

Natthapol Songdej, Fabiola Del carpio-cano, MS, Guangfen Mao, MD, Jeremy Wurtzel, Lawrence Goldfinger, PhD, Michele P. Lambert, MD MSTR, Angara Koneti Rao, MBBS
Journal: Blood
Blood (2020) 136 (Supplement 1): 25–26.
https://doi.org/10.1182/blood-2020-141382
Published: 2020
Journal Articles

Anxiety in Adult Patients Living with ITP Stratified across Different Treatment Types and Groups

Jennifer Diraimo, MS, CCGC, Caroline Kruse, Michele P. Lambert, MD MSTR, Alexandra Kruse
Journal: Blood
Blood (2020) 136 (Supplement 1): 18.
https://doi.org/10.1182/blood-2020-139681
Published: 2020
Journal Articles

Tapering Thrombopoietin Receptor Agonists in Primary Immune Thrombocytopenia: Recommendations Based on the RAND/UCLA Modified Delphi Panel Method

Adam Cuker, MD, Jenny M. Despotovic, DO, Rachael F. Grace, MD, Caroline Kruse, Michele P. Lambert, MD MSTR, Howard Liebman, MD, Roger M. Lyons, MD, Keith R McCrae, MD, Vinod A. Pullarkat, MD, Jeffrey Wasser, MD, David Beenhouwer, MD, Sarah N Gibbs, MPH, Irina Yermilov, MD MPH, MS, Michael S Broder, MD MSHS
Journal: Blood
Blood (2020) 136 (Supplement 1): 6–8.
https://doi.org/10.1182/blood-2020-133262
Published: 2020
Journal Articles

Evidence of Microangiopathy in Children with Sars-Cov-2 Regardless of Clinical Presentation

Caroline Diorio, MD, Kevin O McNerney, MD MSTR, Michele P. Lambert, MD MSTR, Michele Paessler, D.O., Julie Chase, MD PhD, Kandace Gollomp, MD, Benjamin L Laskin, MD, Laura A Vella, MD PhD, Sarah E Henrickson, MDPhD, Emily Liebling, MD, Chakkapong Burudpakdee, BS, Jessica Lee, BS, Fran Balamuth, MDPhD, Allison M Blatz, MD, Kathleen Chiotos, MD MSCE, Julie C Fitzgerald, MD, Therese Giglia, MD MSCE, Audrey R Odom John, MDPhD, Whitney Petrosa, CPNP, Kathleen Sullivan, MD PhD, Char M Witmer, MD, Hamid Bassiri, MDPhD, Edward M Behrens, MD, David T. Teachey, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 28–29.
https://doi.org/10.1182/blood-2020-137240
Published: 2020
Journal Articles

Impact of Therapy Choice on Fatigue in Adults with Immune Thrombocytopenia

Jennifer Diraimo, MS, CCGC, Caroline Kruse, Michele P. Lambert, MD MSTR, Alexandra Kruse
Journal: Blood
Blood (2020) 136 (Supplement 1): 19–20.
https://doi.org/10.1182/blood-2020-139746
Published: 2020
Journal Articles

Racial variation in ITP prevalence and chronic disease phenotype suggests biological differences

Clinical Trials & Observations
Taylor Olmsted Kim, Amanda B. Grimes, Susan E. Kirk, Megan M. Gilbert, Helen D. Reed, Kristen A. Staggers, Lauryn A. Walker, Abinaya Arulselvan, A. Sarah Cohen, Michele P. Lambert, Jenny M. Despotovic
Journal: Blood
Blood (2020) 136 (5): 640–643.
https://doi.org/10.1182/blood.2020004888
Published: 2020
Includes: Supplemental data
Journal Articles

Racial Variation in ITP Prevalence and Rate of Chronic Disease Suggests Biological Differences

Lauryn S. Walker, Taylor Olmsted Kim, MD, Amanda Bell Grimes, MD, Susan Kirk, PA-C, Audrey S. Cohen, Abinaya Arulselvan, Scott E. Wenderfer, MD, Michele P. Lambert, MD, Jenny M. Despotovic, DO, MS
Journal: Blood
Blood (2019) 134 (Supplement_1): 387.
https://doi.org/10.1182/blood-2019-130418
Published: 2019