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Journal Articles

Ianalumab, a Novel Anti-B-Cell Activating Factor (BAFF) Receptor (BAFF-R) Monoclonal Antibody (mAb) in Development for Immune Thrombocytopenia (ITP) and Warm Autoimmune Hemolytic Anemia (wAIHA), Has Demonstrated a Favorable Safety Profile in Sjögren's Syndrome (SjS), Systemic Lupus Erythematosus (SLE) and Chronic Lymphocytic Leukemia (CLL)

Adam Cuker, Hanny Al-Samkari, Wilma Barcellini, Nichola Cooper, Waleed Ghanima, Marc Michel, Raymond SM Wong, Francesco Zaja, Fengkui Zhang, Patrick Urban, Roberto Abi Rached, David J Kuter

Blood (2023) 142 (Supplement 1): 5427.

https://doi.org/10.1182/blood-2023-180055

Published: 2023

Journal Articles

Initial Report of Part B Phase 1/2 Efficacy and Safety Results for Bruton Tyrosine Kinase Inhibitor Rilzabrutinib in Patients with Relapsed Immune Thrombocytopenia

Nichola Cooper, A.J. Gerard Jansen, Robert Bird, Jiří Mayer, Michelle Sholzberg, Michael D. Tarantino, Mamta Garg, Paula F Ypma, Vickie McDonald, Charles Percy, Milan Košťál, Isaac Goncalves, Lachezar H. Bogdanov, Terry B Gernsheimer, Remco Diab, Mengjie Yao, Ahmed Daak, David J Kuter

Blood (2023) 142 (Supplement 1): 685.

https://doi.org/10.1182/blood-2023-177808

Published: 2023

Journal Articles

Patient Experience with Signs, Symptoms, and Daily Impacts of Immune Thrombocytopenia

Waleed Ghanima, Nichola Cooper, Sylvie Bozzi, Ahmed Daak, Imene Gouia, Matias Cordoba, Javier Barrio, Michael Kostikas, Owen Cooper, Howard A. Liebman

Blood (2023) 142 (Supplement 1): 2379.

https://doi.org/10.1182/blood-2023-179124

Published: 2023

Journal Articles

The Effects of Rilzabrutinib, an Oral Bruton Tyrosine Kinase Inhibitor, on Bleeding Symptoms and Health-Related Quality of Life in Patients with Immune Thrombocytopenia

Michael D. Tarantino, A.J. Gerard Jansen, Nichola Cooper, Imene Gouia, Mengjie Yao, Ahmed Daak, David J Kuter

Blood (2023) 142 (Supplement 1): 690.

https://doi.org/10.1182/blood-2023-177811

Published: 2023

Journal Articles

The Lack of Tolerable Treatments Options That Can Induce Durable Responses without Fear of Relapse after Discontinuation Represents a Significant Unmet Need for Patients (Pts) with Immune Thrombocytopenia (ITP): Results from the ITP World Impact Survey (I-WISh) 2.0

James B. Bussel, Nichola Cooper, Waleed Ghanima, Drew Provan, Yoshiaki Tomiyama, Ming Hou, Donald Arnold, Cristina Santoro, Francesco Zaja, Barbara Lovrencic, Mervyn Morgan, Leron Lahav, Michal Winograd, Jennifer MacWhirter - DiRaimo, Tom Bailey, Moyra Aziz, Roberto Abi Rached, Caroline Kruse

Blood (2023) 142 (Supplement 1): 1212.

https://doi.org/10.1182/blood-2023-188527

Published: 2023

Journal Articles

Treatment of Critical Bleeding Events in Patients with Immune Thrombocytopenia: A Systematic Review

Blood (2023) 142 (Supplement 1): 7239.

https://doi.org/10.1182/blood-2023-179448

Published: 2023

Journal Articles

A Phase III Clinical Trial Program Investigating the Efficacy and Safety of Ianalumab in Patients with Primary Immune Thrombocytopenia (VAYHIT1 and VAYHIT2) and Warm Autoimmune Hemolytic Anemia (VAYHIA)

Hanny Al-Samkari, Wilma Barcellini, Nichola Cooper, Waleed Ghanima, Marc Michel, Raymond SM Wong, Francesco Zaja, Fengkui Zhang, Patrick Urban, Alex Allepuz, Justyna Fronczek-Sokol, Jens Haenig, Pascal Edrich, Adam Cuker

Blood (2023) 142 (Supplement 1): 5456.

https://doi.org/10.1182/blood-2023-180647

Published: 2023

Journal Articles

The role of CD8 + T-cell clones in immune thrombocytopenia

Blood (2023) 141 (20): 2417–2429.

https://doi.org/10.1182/blood.2022018380

Published: 2023

Includes: Multimedia, Supplemental data

Journal Articles

Characterisation of Platelet Sensitivity in Severe COVID-19

Rocel C. Saputil, Joanne L. Dunster, Neline Kriek, Yunchuan Ding, Michelle M.H. Tan, Emma Thorley, Clio Pillay, Asad Charania, Margarita Dominguez-Villar, Wayne A. Mitchell, Amna Malik, Jonathan M. Gibbins, Nichola Cooper

Blood (2022) 140 (Supplement 1): 11263–11264.

https://doi.org/10.1182/blood-2022-169954

Published: 2022

Journal Articles

Safety and Efficacy of SARS-CoV-2 Vaccination in Patients with Immune Thrombocytopaenia: a Multi-Centre Review

Sara Stefani, Rocel C. Saputil, Michelle MH Tan, Noora Buti, Deena Paul, Naghma Rizvi, Vashti Ragoonanan, Emma Thorley, Ariam Teklemichael, Camelia Vladescu, Amna Malik, Christine Ademokun, Alice C J Hart, Richard Szydlo, George Adams, James B. Bussel, A.J. Gerard Jansen, Nichola Cooper

Blood (2022) 140 (Supplement 1): 5546–5548.

https://doi.org/10.1182/blood-2022-167614

Published: 2022

Journal Articles

Characterisation of Platelet Sensitivity in Immune Thrombocytopenia Identifies Distinct Subgroups with Either Higher or Lower Platelet Sensitivity

Rocel C. Saputil, Joanne L. Dunster, Neline Kriek, Yunchuan Ding, Anuradha Bhide, Alice C J Hart, Michelle MH Tan, Emma Thorley, Ariam Teklemichael, Wayne A. Mitchell, Amna Malik, Jonathan M. Gibbins, Nichola Cooper

Blood (2022) 140 (Supplement 1): 2691–2692.

https://doi.org/10.1182/blood-2022-167798

Published: 2022

Journal Articles

Retrospective, Observational, Multicenter Study Assessing the Thrombopoietin Receptor Agonist (TPO-RA) Romiplostim and Other Treatments for Patients with Newly Diagnosed or Persistent Primary Immune Thrombocytopenia (ITP) in Routine Clinical Practice in the United Kingdom (UK)

Vickie McDonald, Charlotte Bradbury, Kate Talks, Gillian Lowe, Sue Pavord, Gillian Evans, Manoharan Andiappan, Darcie Sandschafer, Vitor Jose De Sousa Barbosa, Lorraine Stephens, Nichola Cooper

Blood (2022) 140 (Supplement 1): 2678–2680.

https://doi.org/10.1182/blood-2022-157698

Published: 2022

Journal Articles

CD8 + TEMRA Clones Cause Platelet Lysis in Immune Thrombocytopenia

Blood (2022) 140 (Supplement 1): 2209–2210.

https://doi.org/10.1182/blood-2022-166348

Published: 2022

Journal Articles

Total Body Irradiation Is Associated with Higher Prevalence of Cerebral Microbleeds in Haematopoietic Stem Cell Transplant Survivors

Jure Hederih, Asad Charania, Adam Waldman, Jiri Pavlu, Richard Szydlo, Dragana Milojkovic, Eduardo Olavarria, Renuka Palanicawandar, Camelia Vladescu, Jose Ros Soto, Andrew J. Innes, Nichola Cooper

Blood (2022) 140 (Supplement 1): 12910–12912.

https://doi.org/10.1182/blood-2022-168057

Published: 2022

Journal Articles

Eltrombopag Causes Cell Cycle Arrest of T Cells through Iron Chelation and Could Modulate the Immune Response in ITP

Michelle MH Tan, Amna Malik, Anwar A Sayed, Rocel C. Saputil, Sara Zafar, Yunchuan Ding, Emma Thorley, Ariam Teklemichael, Camelia Vladescu, Alice C J Hart, Christine Ademokun, Deena Paul, Naghma Rizvi, Vashti Ragoonanan, Nichola Cooper

Blood (2022) 140 (Supplement 1): 5562–5563.

https://doi.org/10.1182/blood-2022-170449

Published: 2022

Journal Articles

Clinical Predictors of Response to Rilzabrutinib Therapy in Patients with Immune Thrombocytopenia: Exploratory Analysis of a Phase 1/2 Study

David J. Kuter, Waleed Ghanima, Umer Khan, Mengyao Li, Jenny Shan, Ahmed Daak, Nichola Cooper

Blood (2022) 140 (Supplement 1): 5559–5561.

https://doi.org/10.1182/blood-2022-162426

Published: 2022

Journal Articles

Cognitive Impairment in Patients with Immune Thrombocytopenia

Camelia Vladescu, Alice C J Hart, Deena Paul, Christine Ademokun, Ariam Teklemichael, Bridget Chivers, Billy Hopkins, Richard Syzdlo, Naghma Rizvi, Vashti Ragoonanan, Sandra Sigudu, James B. Bussel, Anastastia Gontsarova, Adam Waldman, Nichola Cooper

Blood (2022) 140 (Supplement 1): 5553–5554.

https://doi.org/10.1182/blood-2022-166412

Published: 2022

Journal Articles

Do Children with Immune Thrombocytopenia Have Cerebral Microbleeds?

Alice C J Hart, Ana Maria Cabrera, Camelia Vladescu, Sobia Mustafa, Richard Syzdlo, Rocel C. Saputil, Michelle MH Tan, Amna Malik, David Sharp, Pedro Vicente, Albert Busza, Michael Laffan, Anastasia Gontsarova, Adam Waldman, Nichola Cooper

Blood (2022) 140 (Supplement 1): 48–49.

https://doi.org/10.1182/blood-2022-158176

Published: 2022

Journal Articles

Updated Phase I/II Safety and Efficacy Results for Oral Bruton Tyrosine Kinase Inhibitor Rilzabrutinib in Patients with Relapsed/Refractory Immune Thrombocytopenia

Blood (2021) 138 (Supplement 1): 14.

https://doi.org/10.1182/blood-2021-145128

Published: 2021

Journal Articles

Multi-Arm Trial of Inflammatory Signal Inhibitors (MATIS) for Hospitalised Patients with Mild or Moderate COVID-19 Pneumonia: A Structured Summary of a Study Protocol for a Randomised Controlled Trial

Blood (2021) 138 (Supplement 1): 4200.

https://doi.org/10.1182/blood-2021-148480

Published: 2021

NARROW

Initial Report of Part B Phase 1/2 Efficacy and Safety Results for Bruton Tyrosine Kinase Inhibitor Rilzabrutinib in Patients with Relapsed Immune Thrombocytopenia

Patient Experience with Signs, Symptoms, and Daily Impacts of Immune Thrombocytopenia

The Effects of Rilzabrutinib, an Oral Bruton Tyrosine Kinase Inhibitor, on Bleeding Symptoms and Health-Related Quality of Life in Patients with Immune Thrombocytopenia

The Lack of Tolerable Treatments Options That Can Induce Durable Responses without Fear of Relapse after Discontinuation Represents a Significant Unmet Need for Patients (Pts) with Immune Thrombocytopenia (ITP): Results from the ITP World Impact Survey (I-WISh) 2.0

Treatment of Critical Bleeding Events in Patients with Immune Thrombocytopenia: A Systematic Review

A Phase III Clinical Trial Program Investigating the Efficacy and Safety of Ianalumab in Patients with Primary Immune Thrombocytopenia (VAYHIT1 and VAYHIT2) and Warm Autoimmune Hemolytic Anemia (VAYHIA)

The role of CD8 + T-cell clones in immune thrombocytopenia

Characterisation of Platelet Sensitivity in Severe COVID-19

Safety and Efficacy of SARS-CoV-2 Vaccination in Patients with Immune Thrombocytopaenia: a Multi-Centre Review

Characterisation of Platelet Sensitivity in Immune Thrombocytopenia Identifies Distinct Subgroups with Either Higher or Lower Platelet Sensitivity

Retrospective, Observational, Multicenter Study Assessing the Thrombopoietin Receptor Agonist (TPO-RA) Romiplostim and Other Treatments for Patients with Newly Diagnosed or Persistent Primary Immune Thrombocytopenia (ITP) in Routine Clinical Practice in the United Kingdom (UK)

CD8 + TEMRA Clones Cause Platelet Lysis in Immune Thrombocytopenia

Total Body Irradiation Is Associated with Higher Prevalence of Cerebral Microbleeds in Haematopoietic Stem Cell Transplant Survivors

Eltrombopag Causes Cell Cycle Arrest of T Cells through Iron Chelation and Could Modulate the Immune Response in ITP

Clinical Predictors of Response to Rilzabrutinib Therapy in Patients with Immune Thrombocytopenia: Exploratory Analysis of a Phase 1/2 Study

Cognitive Impairment in Patients with Immune Thrombocytopenia

Do Children with Immune Thrombocytopenia Have Cerebral Microbleeds?

Updated Phase I/II Safety and Efficacy Results for Oral Bruton Tyrosine Kinase Inhibitor Rilzabrutinib in Patients with Relapsed/Refractory Immune Thrombocytopenia

Multi-Arm Trial of Inflammatory Signal Inhibitors (MATIS) for Hospitalised Patients with Mild or Moderate COVID-19 Pneumonia: A Structured Summary of a Study Protocol for a Randomised Controlled Trial

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American Society of Hematology

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American Society of Hematology

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