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Journal Articles

The role of CD8 + T-cell clones in immune thrombocytopenia

Blood (2023) 141 (20): 2417–2429.

https://doi.org/10.1182/blood.2022018380

Published: 2023

Includes: Multimedia, Supplemental data

Journal Articles

CD8 + TEMRA Clones Cause Platelet Lysis in Immune Thrombocytopenia

Blood (2022) 140 (Supplement 1): 2209–2210.

https://doi.org/10.1182/blood-2022-166348

Published: 2022

Journal Articles

Eltrombopag: More Than Just a Thrombopoietin Receptor Agonist (TPO-RA) in Immune Thrombocytopenia (ITP)

Anwar A. Sayed, MBBS, MSc, PhD, Amna Malik, PhD, Grace Ayoola, BSc., Elisa Lucchini, MD, Sasfia Candrianita, MD, Michelle H Tan, BSc, Camelia Vladescu, MSc, Deena Paul, Alice C J Hart, MBBS, BSc, MRCP, FRCPath(Haem), Ahmad Khoder, MD PhD MRCP, ASCP, Nesrina Imami, PhD, Nichola Cooper, MD MRCP

Blood (2019) 134 (Supplement_1): 2364.

https://doi.org/10.1182/blood-2019-122848

Published: 2019

Journal Articles

Active Immune Thrombocytopenia (ITP) Disease Is Characterised By a Reduced Treg:CD8 Effector T Cell Ratio Which Is Modulated By Thrombopoietin-Receptor Agonists (TPO-RA)

Anwar A. Sayed, MBBS, MSc, Amna Malik, PhD, Ahmad Khoder, MD PhD MRCP, George Adams, MBChB, Nichola Cooper, MRCP

Blood (2018) 132 (Supplement 1): 2430.

https://doi.org/10.1182/blood-2018-99-113563

Published: 2018

Journal Articles

A subset of virus-specific CD161 + T cells selectively express the multidrug transporter MDR1 and are resistant to chemotherapy in AML

Blood (2017) 129 (6): 740–758.

https://doi.org/10.1182/blood-2016-05-713347

Published: 2017

Includes: Supplemental data

Journal Articles

IL-10 + regulatory B cells are enriched in cord blood and may protect against cGVHD after cord blood transplantation

Blood (2016) 128 (10): 1346–1361.

https://doi.org/10.1182/blood-2016-01-695122

Published: 2016

Includes: Supplemental data

Journal Articles

Regulatory B cells are enriched within the IgM memory and transitional subsets in healthy donors but are deficient in chronic GVHD

Blood (2014) 124 (13): 2034–2045.

https://doi.org/10.1182/blood-2014-04-571125

Published: 2014

Includes: Supplemental data

Journal Articles

CD161 Expression Identifies a Distinct Subset Of Drug-Effluxing Viral-Specific Memory CD4+ T Cells That Preferentially Survive Cytotoxic Chemotherapy

MD Muharrem Muftuoglu, Abdullah Alsuliman, PhD, Ahmad Khoder, MD, Yong-Oon Ahn, PhD, Enli Liu, MD, MS, Claude Chew, Amir Hamdi, MD, Takuya Sekine, Anushruti Sarvaria, Nichola Cooper, MD, Hugues de Lavallade, MD, David Marin, MD, Kate Stringaris, MD, MRCP, FRCPath, Michael R. Verneris, MD, Elizabeth J Shpall, MD, Katayoun Rezvani, MD, PhD

Blood (2013) 122 (21): 2024.

https://doi.org/10.1182/blood.V122.21.2024.2024

Published: 2013

Journal Articles

B Cell With Regulatory Function Are Enriched Within Transitional and IgM Memory B Cell Subsets In Healthy Donors But Are Reduced and Functionally Impaired In Patients With Chronic Graft-Versus-Host Disease

Blood (2013) 122 (21): 4478.

https://doi.org/10.1182/blood.V122.21.4478.4478

Published: 2013

Journal Articles

Tyrosine kinase inhibitors impair B-cell immune responses in CML through off-target inhibition of kinases important for cell signaling

Blood (2013) 122 (2): 227–238.

https://doi.org/10.1182/blood-2012-11-465039

Published: 2013

Includes: Supplemental data

Journal Articles

Defective Natural Killer (NK) Receptor Expression and Effector Function in Acute Myeloid Leukemia Partially Normalize At Remission and Predict Response to Chemotherapy.

Kate Stringaris, MD, MRCP, FRCPath, Takuye Sekine, Ahmad Khoder, M.D., Abdullah Alsuliman, Pavlu Jiri, Anushruthi Sarvaria, David Marin, Jane Apperley, A. John Barrett, MD, Katayoun Rezvani, M.D., PhD

Blood (2012) 120 (21): 2591.

https://doi.org/10.1182/blood.V120.21.2591.2591

Published: 2012

Journal Articles

Dasatinib may overcome the negative prognostic impact of KIR2DS1 in newly diagnosed patients with chronic myeloid leukemia

Sara Ali, Ruhena Sergeant, Stephen G. O'Brien, Letizia Foroni, Corinne Hedgley, Gareth Gerrard, Dragana Milojkovic, Kate Stringaris, Ahmad Khoder, Abdullah Alsuliman, Maria Gilleece, Ian H. Gabriel, Nichola Cooper, John M. Goldman, Jane F. Apperley, Richard E. Clark, David Marin, Katayoun Rezvani

Blood (2012) 120 (3): 697–698.

https://doi.org/10.1182/blood-2012-04-421016

Published: 2012

Journal Articles

Chronic Myeloid Leukemia Patients on Tyrosine Kinase Inhibitor Have Normal T Cell Responses to Vaccination but An Impaired IgM Humoral Response Associated with Loss of Discrete Memory B Cell Subsets,

Blood (2011) 118 (21): 3753.

https://doi.org/10.1182/blood.V118.21.3753.3753

Published: 2011

Journal Articles

2009 Pandemic Influenza A H1N1 Vaccination In the Patients with Hematologic Malignancies: Requirement for Repeated Dosing to Optimize Seroprotection

Blood (2010) 116 (21): 677.

https://doi.org/10.1182/blood.V116.21.677.677

Published: 2010

Journal Articles

KIR2DS1 Genotype Predicts for Cytogenetic Response, Progression-Free Survival and Overall Survival In Patients with Chronic Phase CML on Imatinib

Ian H Gabriel, MD, David Marin, MD, FRCP, Shahzad Ahmad, Mr, Letizia Foroni, Hugues de Lavallade, MD, Richard E. Clark, MBBS, MD, FRCP, FRCPath, Stephen O'Brien, PhD, Ruhena Sergeant, Dragana Milojkovic, MD, Marco Bua, Abdullah Alsuliman, Ahmad Khoder, Dr, Kate Stringaris, MD, MRCP, FRCPath, Nichola Cooper, MD, John M. Goldman, DM, FRCP, FRCPath, FMedSci, Jane F. Apperley, Katayoun Rezvani, MD, PhD

Blood (2010) 116 (21): 888.

https://doi.org/10.1182/blood.V116.21.888.888

Published: 2010

Journal Articles

A Distinct Signature of Natural Killer Cell KIR Gene Frequencies In Secondary AML Compared with De Novo AML and Normal Controls

Kate Stringaris, MD, MRCP, FRCPath, A. John Barrett, MD, Robert Hills, MA, MSc, DPhil, David C Linch, MD, FMedSci, Rosemary Gale, PhD, Christopher Allen, Paula Garland, MBBS, MRCP, Ruhena Sargent, Hugues de Lavallade, Abdullah Alsuliman, Ahmad Khoder, Dr, Ian H Gabriel, Dr, Takuya Sekine, Alan Burnett, Katayoun Rezvani, Jane F. Apperley

Blood (2010) 116 (21): 1697.

https://doi.org/10.1182/blood.V116.21.1697.1697

Published: 2010

Journal Articles

Interaction between KIR3DS1 and HLA-Bw4 predicts for progression-free survival after autologous stem cell transplantation in patients with multiple myeloma

Ian H. Gabriel, Ruhena Sergeant, Richard Szydlo, Jane F. Apperley, Hugues deLavallade, Abdullah Alsuliman, Ahmad Khoder, David Marin, Edward Kanfer, Nichola Cooper, John Davis, Donald MacDonald, Marco Bua, Letizia Foroni, Chrissy Giles, Dragana Milojkovic, Amin Rahemtulla, Katayoun Rezvani

Blood (2010) 116 (12): 2033–2039.

https://doi.org/10.1182/blood-2010-03-273706

Published: 2010

Journal Articles

T-Cell and B-Cell Responses After Vaccination against Influenza Virus and Pneumococcus in Chronic Phase CML Patients Treated with Tyrosine Kinase Inhibitors.

Hugues de Lavallade, MD, MsC, Melanie Hart, PhD, Ian H Gabriel, Dr, Peter Kelleher, MD, PhD, Abdullah Alsuliman, PhD, Ahmad Khoder, MD, Dragana Milojkovic, MD, Letizia Foroni, Marco Bua, MD, Jane F. Apperley, MBChB, FRCP, FRCPath, John M Goldman, DM, FCRP, David Marin, MD, Katayoun Rezvani, MD, PhD

Blood (2009) 114 (22): 2214.

https://doi.org/10.1182/blood.V114.22.2214.2214

Published: 2009

Journal Articles

Presence of the Killer Immunoglobulin-Like Gene KIR3DS1 Is Associated with Poor Progression Free and Overall Survival Following Autologous Stem Cell Transplantation in Patients with Myeloma.

Ian H Gabriel, Dr, Ruhena Sargent, Dr, Hugues de Lavallade, Richard Szydlo, Jane Apperley, Ahmad Khoder, Dr, Abdullah Alsuliman, David Marin, Letizia Foroni, John Davis, Chrissy Giles, Edward Kanfer, MD, Amin Rahemtulla, MBBS, PhD, FRCP, Katayoun Rezvani, MD, PhD

Blood (2009) 114 (22): 2840.

https://doi.org/10.1182/blood.V114.22.2840.2840

Published: 2009

NARROW

The role of CD8 + T-cell clones in immune thrombocytopenia

CD8 + TEMRA Clones Cause Platelet Lysis in Immune Thrombocytopenia

Eltrombopag: More Than Just a Thrombopoietin Receptor Agonist (TPO-RA) in Immune Thrombocytopenia (ITP)

Active Immune Thrombocytopenia (ITP) Disease Is Characterised By a Reduced Treg:CD8 Effector T Cell Ratio Which Is Modulated By Thrombopoietin-Receptor Agonists (TPO-RA)

A subset of virus-specific CD161 + T cells selectively express the multidrug transporter MDR1 and are resistant to chemotherapy in AML

IL-10 + regulatory B cells are enriched in cord blood and may protect against cGVHD after cord blood transplantation

Regulatory B cells are enriched within the IgM memory and transitional subsets in healthy donors but are deficient in chronic GVHD

CD161 Expression Identifies a Distinct Subset Of Drug-Effluxing Viral-Specific Memory CD4+ T Cells That Preferentially Survive Cytotoxic Chemotherapy

B Cell With Regulatory Function Are Enriched Within Transitional and IgM Memory B Cell Subsets In Healthy Donors But Are Reduced and Functionally Impaired In Patients With Chronic Graft-Versus-Host Disease

Tyrosine kinase inhibitors impair B-cell immune responses in CML through off-target inhibition of kinases important for cell signaling

Defective Natural Killer (NK) Receptor Expression and Effector Function in Acute Myeloid Leukemia Partially Normalize At Remission and Predict Response to Chemotherapy.

Dasatinib may overcome the negative prognostic impact of KIR2DS1 in newly diagnosed patients with chronic myeloid leukemia

Chronic Myeloid Leukemia Patients on Tyrosine Kinase Inhibitor Have Normal T Cell Responses to Vaccination but An Impaired IgM Humoral Response Associated with Loss of Discrete Memory B Cell Subsets,

2009 Pandemic Influenza A H1N1 Vaccination In the Patients with Hematologic Malignancies: Requirement for Repeated Dosing to Optimize Seroprotection

KIR2DS1 Genotype Predicts for Cytogenetic Response, Progression-Free Survival and Overall Survival In Patients with Chronic Phase CML on Imatinib

A Distinct Signature of Natural Killer Cell KIR Gene Frequencies In Secondary AML Compared with De Novo AML and Normal Controls

Interaction between KIR3DS1 and HLA-Bw4 predicts for progression-free survival after autologous stem cell transplantation in patients with multiple myeloma

T-Cell and B-Cell Responses After Vaccination against Influenza Virus and Pneumococcus in Chronic Phase CML Patients Treated with Tyrosine Kinase Inhibitors.

Presence of the Killer Immunoglobulin-Like Gene KIR3DS1 Is Associated with Poor Progression Free and Overall Survival Following Autologous Stem Cell Transplantation in Patients with Myeloma.

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American Society of Hematology

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American Society of Hematology

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